Differentiating between adrenocortical carcinoma and pheochromocytoma by a CT-based radiomics model: a multicenter retrospective study by Yinyao Chao, Hongzhang Zhu, Wenyi Yang, Haohua Yao, Nan Ma, Xianda Chen, Jing Zhao, Huali Ma, Zhenhua Liu, Hui Han, Zhuowei Liu, Kai Yao, Yiyao Li, Peng Wu, Jingtong Zhang, Bin Li, Shengjie Guo

“…Radiomics features were extracted from different phases of contrast-enhanced CT and then selected by a two-step procedure. The radiomics model was developed in a cohort of 109 patients from Institution 1, then the model performance was evaluated in the external test cohort of 49 patients from Institutions 2 and 3. …”
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Establishment of <i>Agrobacterium</i>-Mediated Transient Transformation System in Sunflower by Fangyuan Chen, Lai Wang, Qixiu Huang, Run Jiang, Wenhui Li, Xianfei Hou, Zihan Tan, Zhonghua Lei, Qiang Li, Youling Zeng

“…In this study, we established an efficient transient expression transformation system for sunflower using three methods: <i>Agrobacterium</i>-mediated infiltration, injection, and ultrasonic-vacuum. The detailed procedures were as follows: <i>Agrobacterium</i> GV3101 carrying a <i>GUS</i> reporter gene on the pBI121 vector with an OD₆₀₀ of 0.8 as the bacterial suspension and 0.02% Silwet L-77 as the surfactant were utilized in all three approaches. …”
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Study of the immunological efficacy and safety of a candidate vaccine against Lassa hemorrhagic fever by O. Popova, O. V. Zubkova, T. A. Ozharovskaia, D. I. Zrelkin, D. V. Voronina, P. P. Goldovskaya, V. Yu. Kan, I. V. Dolzhikova, A. V. Kovyrshina, D. M. Grousova, I. A. Ermolova, D. V. Shcheblyakov, D. Yu. Logunov, A. L. Gintsburg

“…Standard genetic engineering techniques, molecular biology techniques, virological methods, and animal testing procedures were used in the course of the study. A combined vector candidate vaccine for the prevention of Lassa hemorrhagic fever has been designed and characterized. …”
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Surgical Outcomes of Video‐Assisted Thoracic Surgery Combined With Computed Tomography‐Guided Microwave Ablation for Lung Cancer Presenting as Multiple Ground‐Glass Opacities: A 5‐... by Bin Huang, Chuanfei Zhan, Pengcheng Yu, Yifan Xu, Muhammad Zunair Bhatti, TianMing Chen, WenDa Yin, Zhifei Ma, Chi Su, Zhongqiu Wang, Dongjie Feng, Tian Shen, Xiaokang Shen, Dongqing Lu, Lin Zheng, Shilin Chen

“…The outcomes assessed in this study included the feasibility and safety profile of the combined procedure, as well as event‐free survival (EFS), local progression‐free survival (LPFS), and overall survival (OS). …”
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Radioresistant mouse pheochromocytoma cell lines by Sandy Lemm, Sandy Lemm, Marcel Gebhardt, Thomas Groß, Susan Richter, Susan Richter, Martin Ullrich, Jens Pietzsch, Jens Pietzsch

“…However, the underlying mechanisms of radioresistance in PCC/PGL remain largely unknown and appropriate models are missing.MethodsTwo genetically modified mouse pheochromocytoma (MPC) cell lines, one positive and one negative for hypoxia-inducible factor 2α expression (MPC+HIF-2α and MPC+EV [empty vector], respectively), were X-ray-conditioned through fractionated irradiation at sublethal doses. Two procedures were tested: one allowed for recovery between each irradiation step (recIR), while the other demanded daily irradiation (dayIR). …”
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Biodegradation and biocompatibility of calcium phosphate-coated magnesium in eye environment, in vitro and in vivo by Yi Chen, Yi Lin, Wangdu Luo, Huanhuan Gao, Yaobo Hu, Liying Qiao, Jia She, Lin Xie, Xiangji Li, Yong Wang, Fusheng Pan

“…It is concluded that HA-coated Mg implantation is a promising adjunctive procedure to improve the success rate of trabeculectomy. …”
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Variability of important fatty acids and vitamin E in Almond (Prunus dulcis) genotypes of Kashmir estimated by validated GC-FID and HPLC by Mohsin Ahmad Hajam, Asif Mohi Ud Din Rather, Ghulam Irshad Hassan, Ejaz Ahmad Parray, Ifshan Malik, Waseem Raja, Ishrat Jan, Gholamreza Abdi, Rana Muhammad Aadil

“…All the validated parameters are well demonstrated in the method validation procedure and the corresponding values were found within acceptable range. …”
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Nontoxic Multinodular Goitre and Incidental Thyroid Cancer: What Is the Best Surgical Strategy?—A Retrospective Study of 2032 Patients by Krzysztof Kaliszewski, Beata Wojtczak, Jędrzej Grzegrzółka, Jacob Bronowicki, Sawsan Saeid, Bartłomiej Knychalski, Zdzisław Forkasiewicz

“…A discussion with regard to the most optimal surgical procedure in nontoxic multinodular goitre (NTMNG). …”
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Comparison of outcome of conventional bipolar vs. laser en bloc transurethral resection of bladder tumor: A prospective study by Apurv Shukla, Partha Protim Mondal, Sudipta Kumar Singh, Shashi Kant Tewary, Arvind Arvind, Ankit Agarwal, Ranjan Kumar Dey

“…Although the vast majority of newly diagnosed bladder cancers are for nonmuscle-invasive disease and may be treated with endourological procedures, correct initial staging is critical. The quality of transurethral resection of bladder tumors (TURBT) strongly determines patient prognosis and overall UBC treatment costs Goals of new strategies should include avoiding second TURBTs and lowering overall treatment regimens. …”
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Deep sedation using intranasal dexmedetomidine followed by intravenous propofol for pediatric dental treatment by Yun Liu, Binghua Li, Xiaoran Wu, Bin Xia, Xudong Yang, Tong Cheng

“…Conclusions This study establishes intranasal dexmedetomidine premedication followed by target-controlled propofol infusion sedation as a safe, effective alternative to general anesthesia for short-duration pediatric dental procedures (< 2 h).…”
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The effects of vaginal infections on pregnancy outcomes: a retrospective cohort study in China by Dongting Yao, Xinyu Tang, Minghui Xue, Keyu Zhu, Wei Li, Ze Chen, Meng Ni, Baihe Li, Yanan Tang, Zhenying Lin, Chunyu Cheng, Yi Hu, Xiaorui Liu, Qianqian Zhang, Jiuru Zhao, Haiou Yang, Zhiwei Liu

“…Data were collected from medical records, with vaginal infection diagnoses confirmed through standard laboratory procedures. This study included women who registered and delivered at our hospital between 2021 and 2023. …”
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Spinal cord stimulator utilization trends and predictors of unsuccessful trial-to-implant conversion by Wesley Day, BS, Gwyneth C Maloy, BA, Adam D. Winter, BS, Kenneth B Chapman, MD, Anthony E Seddio, BS, Rushabh H Doshi, BS, Philip P Ratnasamy, BS, Arya G Varthi, MD, Mitchell S. Fourman, MD, Jonathan N Grauer, MD

“…By defining clinical and nonclinical factors associated with failure for conversion from trial to implant, selection processes can be further optimized by specialists performing these procedures.…”
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Mapping patient encounters to identify recruitment timepoints after brain tumour surgery: a cohort and cross-sectional study by Lewis Thorne, Siddharth Sinha, Hani J Marcus, Jack Penn, Michael Kosmin, Naomi Fersht, James Booker, Nicola Newall, John G Hanrahan, Simon C Williams, Ciaran S Hill

“…The flow of encounters reflected the process map with 90.7% accuracy, with key timepoints identified at imaging and biopsy/surgical procedures. A cross-sectional survey conducted during outpatient neuro-oncology clinics identified that patients predominantly used self-directed internet searches (n=17, 68%) and verbal information from their neurosurgeon (n=16, 64%) to learn about clinical trials.Conclusions This study demonstrates the effectiveness of process mapping in identifying key timepoints for automated data collection and opportunities for quality improvement for clinical trial recruitment. …”
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The establishment of a clinical protocol for hostages returning from captivity by Daniel Trotzky, Idit Segal, Ronit Koren, Orna Tal, Gal Pachys, Galina Goltzman, Karen Or, Margarita Alpro, Ronit Zaidenstein, Maayan Bachar, Baruch Berzon, Roni Enten Vissoker, Inbar Hartmann, Miri Avraham, Vered Shinar, Ada Azar, Osnat Levtzion Korach

“…Method The process of the creation of procedures for implementation of and the clinical protocol itself is described. …”
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Higher levels of D2R and D3R in the frontal–striatal regions are associated with reduced perseverative reward seeking after opioid abstinence by Yingying Li, Yingying Li, Xigeng Zheng, Xigeng Zheng, Cong Gao, Cong Gao, Shao Li, Zhengkui Liu, Zhengkui Liu, Meixuan Lv, Meixuan Lv, Fei Xiao, Fei Xiao, Yunjing Bai, Yunjing Bai

“…While D3R has been considered a potential target for treating drug dependence, the connection between D3R in the prefrontal-striatal regions and maladaptive drug-related behaviors remains poorly understood.MethodsThis study utilized two high-cost tasks to investigate perseverative reward seeking, specifically conflict-based approaching behavior and persistent responding behavior under a progesterone receptor (PR) procedure. Additionally, D2R and D3R levels in the medial prefrontal cortex (mPFC) and striatum were examined through Western blotting.ResultsAfter each task, male rats were divided into two subpopulations: high-approaching vs. low-approaching and high-responding vs. low-responding. …”
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Health-related quality of life in patients with gastrointestinal stromal tumor: data from a real-world cohort compared with a normative population by D. van de Wal, D. den Hollander, I.M.E. Desar, H. Gelderblom, A.W. Oosten, A.K.L. Reyners, N. Steeghs, W.T.A. van der Graaf, O. Husson

“…Background: Treatment and follow-up (FU) care procedures for gastrointestinal stromal tumors (GISTs) impose great challenges on patients and could potentially affect their health-related quality of life (HRQoL). …”
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First-in-man Experience of a New Transcatheter Edge-to-edge Repair System Neoblazar in Patients With Severe Tricuspid Regurgitation by Xiang Chen, Da Zhu, Maolong Su, Xu Chen, Pianpian Yan, Hongmei Wen, Bin Wang, Nianguo Dong, Xiangbin Pan, Yan Wang

“…Immediately after the TEER procedure with the Neoblazar system, massive tricuspid regurgitation (grade 5+) at baseline decreased to moderate-severe tricuspid regurgitation (grade 3+) in 2 patients and the optimal tricuspid regurgitation reduction (severe tricuspid regurgitation (grade 4+) to mild tricuspid regurgitation (grade 1+)) were achieved in 6 patients. …”
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Therapeutic efficacy of intra-arterial administration of induced pluripotent stem cells-derived neural progenitor cells in acute experimental ischemic stroke in rats by D. D. Namestnikova, I. L. Gubskiy, D. I. Salikhova, G. E. Leonov, K. K. Sukhinich, P. A. Melnikov, D. A. Vishnevskiy, E. A. Cherkashova, A. N. Gabashvili, T. B. Bukharova, V. V. Burunova, T. Kh. Fatkhudinov, V. P. Chekhonin, L. V. Gubsky, S. L. Kiselev, D. V. Goldstein, K. N. Yarygin

“…However, exploration of less invasive transplantation options is essential, because stereotaxic transplantation is a complex procedure and can be applied to humans only by vital indications in a specialized neurological ward. …”
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Dose Calibrator Linearity Testing: Radioisotope 99mTc or 18F? An Alternative for Reducing Costs in Nuclear Medicine Quality Control by José Willegaignon, Marcelo Sapienza, George Coura-Filho, Alexandre Garcez, Carlos Alves, Marissa Cardona, Ricardo Gutterres, Carlos Buchpiguel

“…Nevertheless, this information, along with the high potential of exposure and the high cost of 18 F, implies that 99m Tc should preferably be employed for linearity testing in clinics that normally use 18 F, without the risk of prejudicing either the procedure itself or the guarantee of a high-quality nuclear medicine service.…”
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Neonatal factors predictive for respiratory and gastro-intestinal morbidity after esophageal atresia repair by Maissa Rayyan, Malaika Embrechts, Hans Van Veer, Raf Aerts, Ilse Hoffman, Marijke Proesmans, Karel Allegaert, Gunnar Naulaers, Nathalie Rommel

“…We used linear models with a binomial distribution to determine risk factors for gastro-intestinal or respiratory complicated evolution and a backward stepwise elimination procedure to reduce models until only significant variables remained in the model. …”
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