A deep learning model based on chest CT to predict benign and malignant breast masses and axillary lymph node metastasis by Jingxiang Sun, Xiaoming Xi, Mengying Wang, Menghan Liu, Xiaodong Zhang, Haiyan Qiu, Youxin Zhang, Taian Fu, Yanan Du, Wanqing Ren, Dawei Wang, Guang Zhang

“…This study aims to develop a deep learning model based on chest CT imaging to improve the preliminary assessment of breast lesions, potentially reducing the need for costly follow-up procedures such as magnetic resonance imaging (MRI) or positron emission tomography-CT and alleviating the financial and emotional burden on patients. …”
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‘High hopes for treatment’: Australian stakeholder perspectives of the clinical translation of advanced neurotherapeutics for rare neurological diseases by Christina Q. Nguyen, Didu S. T. Kariyawasam, Tsz Shun Jason Ngai, James Nguyen, Kristine Alba‐Concepcion, Sarah E. Grattan, Elizabeth E. Palmer, Kate Hetherington, Claire E. Wakefield, Russell C. Dale, Sue Woolfenden, Shekeeb Mohammad, Michelle A. Farrar

“…Participants were motivated to intensify RND clinical trial activity and access to advanced therapies; however, concerns around informed consent, first‐in‐human trials and clinical trial procedures were evident. There was high‐risk tolerance despite substantial uncertainties and knowledge gaps. …”
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A multidimensional comparison of the benefit degrees for patients between ileostomy and colostomy by Yuhang Wang, Lei Cheng, Weichao Li, Zhaowei Gao, Jiayuan Miao, Chunlei Zhang, Zhiqiang Zhu, Feng Zhao, Jing Yi, Chunyuan Liu

“…This may be related to factors such as anatomical and physiological characteristics, the nature of intestinal contents, the location of the stoma, and surgical procedures. At the same time, complications can be prevented through multiple measures before, during, and after the operation. …”
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Aquatic Education for School Children: An Educational Expert Statement from the Nordic Consortium by Monika Haga, Arja Sääkslahti, Katarina Schenker, Tine Hedegaard Bruun, Julie Dalgaard Guldager, Þórdís Lilja Gísladóttir, Bára Berghamar Danielsen, Egil Galaaen Gjølme, Jon Sundan, Helgi Winther Olsen, Øyvind Bjerke

“…The data for this position statement were generated through presentations, discussions and comparisons of documents, and were analyzed using Eggebø’s (2020) collective qualitative analysis procedure. Analysis and statement outcome: Aquatic education and swimming lessons are mandatory in all Nordic countries, teaching swimming skills from grades 1–10. …”
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Management of biological waste of patients after radionuclide therapy by L. A. Chipiga, A. V. Vodovatov, I. A. Zvonova, A. A. Stanzhevsky, A. V. Petryakova, E. E. Anokina, K. S. Velichkina, S. A. Ryzhov

“…As a results of preliminary computations, some nuclear medicine procedure will not lead to generation of liquid radioactive waste from biological waste of patients in sewerage system in usual operating condition and special sewerage is not strictly necessary. …”
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Histology and Immunohistochemistry of Adipose Tissue: A Scoping Review on Staining Methods and Their Informative Value by Tom Schimanski, Rafael Loucas, Marios Loucas, Oliver Felthaus, Vanessa Brébant, Silvan Klein, Alexandra Anker, Konstantin Frank, Andreas Siegmund, Andrea Pagani, Sebastian Geis, Sophia Theresa Diesch, Andreas Eigenberger, Lukas Prantl

“…Background: Histological and immunohistochemical analyses of adipose tissue are essential for evaluating the quality and functionality of lipoaspirates in regenerative medicine and fat grafting procedures. These methods provide insights into tissue viability, cellular subtypes, and extracellular matrix (ECM) composition—all factors influencing graft retention and clinical outcomes. …”
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Modified pulmonary artery banding: A novel strategy for balancing pulmonary blood flow with transposed great arteriesCentral MessagePerspective by Gananjay G. Salve, MS, MCh, Andrew D. Cole, BAppSci (Hon), Ian A. Nicholson, FRACS, David S. Winlaw, MD, FRACS, Richard B. Chard, FRACS, Yishay Orr, PhD, FRACS

“…Results: The disease spectrum included dextro transposition of the great arteries (d-TGA) with multiple ventricular septal defects (VSDs) (n = 4), Taussig–Bing anomaly (n = 3), d-TGA with VSD and hypoplastic right ventricle (RV) (n = 3), double-inlet left ventricle with l-TGA (n = 2), and congenitally corrected TGA with double-outlet RV (n = 1). The Lecompte procedure was performed in 10 patients. Predischarge echocardiography revealed a band gradient of 61 mm Hg (interquartile range [IQR], 40-90 mm Hg) for BVR/1-1/2 ventricular repair (n = 7) and 49 mm Hg (IQR, 37-61 mm Hg) for UVR (n = 6). …”
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Comparison of the proteomic landscape in experimental ischemia reperfusion with versus without ischemic preconditioning by Yalda Kakaei, Shafaat Hussain, Ahmed Elmahdy, Evelin Berger, Aaron Shekka Espinosa, Valentyna Sevastianova, Zahra Sheybani, Amin Al-Awar, Mana Kalani, Sandeep Jha, Ermir Zulfaj, Amirali Nejat, Abhishek Jha, Tetiana Pylova, Maryna Krasnikova, Erik Axel Andersson, Vagner Ramon Rodrigues Silva, Elmir Omerovic, Björn Redfors

“…Rats underwent either IPC with two 5-minute ischemia/reperfusion cycles followed by a 13.5-minute ischemic period or the procedure without IPC (no ischemic preconditioning, NIPC). …”
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Non-eosinophilic esophagitis eosinophilic gastrointestinal diseases are more prevalent than eosinophilic esophagitis in Korean children: from a multicenter study based on new diagn... by Kunsong Lee, Ben Kang, Eun Sil Kim, Dae Yong Yi, Tae Hyeong Kim, Yoo Min Lee, Sujin Choi, Byung-Ho Choe

“…Clinical, laboratory, and endoscopic findings were analyzed.ResultsAmong a total of 4,972 pediatric endoscopic procedures (3,300 upper and 1,672 lower), 63 cases (1.3%) of EGIDs were diagnosed, with non-EoE EGIDs (65.1%) being more prevalent than EoE (34.9%). …”
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Population differences in vaccine responses (POPVAC): scientific rationale and cross-cutting analyses for three linked, randomised controlled trials assessing the role, reversibili... by Pontiano Kaleebu, Emily Webb, Moses Muwanga, Gyaviira Nkurunungi, Ludoviko Zirimenya, Agnes Natukunda, Jacent Nassuuna, Gloria Oduru, Caroline Ninsiima, Christopher Zziwa, Florence Akello, Robert Kizindo, Mirriam Akello, Anne Wajja, Henry Luzze, Stephen Cose, Alison M Elliott, Alison Elliott, Rebecca Amongin, Beatrice Nassanga, Irene Nambuya, Prossy Kabuubi, Emmanuel Niwagaba, Grace Kabami, Helen Akurut, Alex Mutebe, Milly Namutebi, Caroline Onen, Esther Nakazibwe, Josephine Tumusiime, Susan Amongi, Moses Sewankambo, Denis Nsubuga, Samuel Kiwanuka, Fred Kiwudhu, David Abiriga, Moses Kizza, Samsi Nansukusa, Hermelijn Smits, Maria Yazdanbakhsh, Govert van Dam, Paul Corstjens, Sarah Staedke, James Kaweesa, Edridah Tukahebwa, Elly Tumushabe

“…We hypothesise that urban–rural (and regional and international) differences in vaccine responses are mediated to an important extent by differential exposure to chronic infections, particularly parasitic infections.Methods and analysis Three related trials sharing core elements of study design and procedures (allowing comparison of outcomes across the trials) will test the effects of (1) individually randomised intervention against schistosomiasis (trial A) and malaria (trial B), and (2) Bacillus Calmette-Guérin (BCG) revaccination (trial C), on a common set of vaccine responses. …”
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Cognition and experience of surgical incisions in patients undergoing laparoscopic surgery with enhanced recovery after surgery protocol: A qualitative study by Hongxia Xu, Yihong Xu, Gongjie Shi, Jiaqi Lu, Liping Zhu, Guibing He, Xiao Liang

“…The participants were adults (≥18 years) who underwent elective laparoscopic abdominal surgery under ERAS, excluding those with cognitive impairments, language barriers, or emergency procedures. Semi-structured interviews, covering physical function, social function, emotional function, self and others’ acceptance, and confidence in the nature and treatment of the disease, were audio-recorded and transcribed verbatim and guided by a thematic framework co-developed by surgeons, nurses, and psychologists. …”
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Vaporized hydrogen peroxide sterilization of powered air-purifying respirators: Efficacy and safety assessment by Yeerzati Tuluhongtayi, Wenjun He, Kun Cai, Weifang Han, Sheng Zhang, Jun Liu, Wenwen Lei, Zongxing Zhang, Jiancheng Qi, Guizhen Wu

“…However, brand-specific protocols and extended ventilation procedures are required to ensure effective sterilization and reduce H2O2 residues to safe level.…”
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Comparative outcomes of transcatheter aortic valve replacement in bicuspid vs. tricuspid aortic valve stenosis patients: insights from the SWEDEHEART registry by Antros Louca, Petur Petursson, Joakim Sundström, Araz Rawshani, Henrik Hagström, Magnus Settergren, Stefan James, Sasha Koul, Kristofer Skoglund, Dan Ioanes, Sebastian Völz, Anna Myredal, Oskar Angerås, Truls Råmunddal

“…Methods: This observational study included all patients who underwent TAVR in Sweden from 2016 to 2022, excluding those with pure aortic insufficiency and valve-in-valve procedures. Only Evolut-, SAPIEN-, ACURATE-, and Portico/Navitor-family devices were included. …”
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An Automated Microfluidic Platform for In Vitro Raman Analysis of Living Cells by Illya Klyusko, Stefania Scalise, Francesco Guzzi, Luigi Randazzini, Simona Zaccone, Elvira Immacolata Parrotta, Valeria Lucchino, Alessio Merola, Carlo Cosentino, Ulrich Krühne, Isabella Aquila, Giovanni Cuda, Enzo Di Fabrizio, Patrizio Candeloro, Gerardo Perozziello

“…This study highlights the potential use of this platform as an alternative to conventional culturing and analysis procedures, considering that cell culturing, optical imaging, and Raman spectroscopy can be performed simultaneously on living cells with minimal cellular stress and without the need for labeling or fixation.…”
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MODELING PROCESS OF PALLIATIVE PHARMACEUTICAL CARE AS A COMPONENT OF PHARMACEUTICAL SAFETY AT THE LOCAL LEVEL by I. A. Tueva, L. N. Geller, A. L. Myimrina, L. A. Escheva, I. V. Vidyasova

“…The introduction of a cluster model of interaction between medical and pharmaceutical staff at the outpatient stage of palliative care minimizesthe time spent on performing auxiliary procedures. Conclusion. In the conditions of an industrial center for 100 thousand inhabitants, at least one pharmacy organization dealing with the release of narcotic drug and psychotropic substances and their precursors is necessary for the proper and stable provision of patients in need of palliative care. …”
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Patient characteristics and adverse effects of allogeneic blood transfusion following lower extremity joint replacement in rheumatoid arthritis: a nationwide inpatient sample datab... by Wenyan Geng, Lulu Ye, Xuegao Yu, Qinfeng Yang, Linlin Wang, Xiaodan Li, Qing Xiao, Jian Wang

“…Despite the potential for adverse outcomes associated with blood transfusion, the risks related to this procedure in RA patients remain underexplored, particularly within the framework of a large-scale national dataset. …”
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Laparoscopic excision of deep rectovaginal endometriosis in BSGE endometriosis centres: a multicentre prospective cohort study by Paul Smith, Lucky Saraswat, Sanjay Vyas, Thomas Ind, Ertan Saridogan, Elizabeth Ball, Edward Morris, James Clark, Tony Chalhoub, David Rowlands, Moiad Alazzam, Dominic Byrne, Tamara Curnow, Alfred Cutner, T Justin Clark, Iris Menninger, Yousri Afifi, Kevin Phillips, Saikat Banerjee, Robert Richardson, Jeremy Hawe, Barry Whitlow, Emmanuel Ofuasia, Ashwini Trehan, Tyrone Carpenter, Christian Becker, Stuart Jack, Kumar Kunde, Chris Barnick, Alan Farthing, Graham Phillips, John Bidmead, Mohamed Abdel-aty, George Botros, Marlin Mubarak, Christian Kremer, Stanley Okolo, Edmond Edi-osagi, Kamel Shehata-iskander, Gaity Ahmad, Jonathan Frappell, Brice Rodriguez, Yemi Coker, Gourab Misra, Adam Moors, Chris Guyer, Caroline Overton, Suku George, Oliver Chappatte, Richard Penketh, Funlayo Odejinmi, Keith Louden, Jon Hughes

“…Gastrointestinal complications (enterotomy, anastomotic leak or fistula) occurred in 52 (1.1%) operations and of the urinary tract (ureteric/bladder injury or leak) in 49 (1.0%) procedures.Conclusion Laparoscopic surgical excision of rectovaginal endometriosis appears to be effective in treating pelvic pain and bowel symptoms and improving health-related quality of life and has a low rate of major complications when performed in specialist centres.…”
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Long-term kidney complications in childhood leukemia survivors: a study from the Childhood and Adolescent Leukaemia (LEA) project by Carine Domenech, Paul Saultier, Zeinab Hamidou, Marie-Dominique Tabone, Marlène Pasquet, Virginie Gandemer, Stéphane Ducassou, Marilyne Poirée, Dominique Plantaz, Jean-Hugues Dalle, Pascal Chastagner, Sandrine Thouvenin, Justyna Kanold, Alexandre Theron, Isabelle Pellier, Yves Reguerres, André Baruchel, Pascal Auquier, Justine Bacchetta, Gérard Michel, Laurence Derain-Dubourg

“…Among the 1676 patients included, the median [interquartile range] age at evaluation was 15.8 [11.3-20.5] years, with a median follow-up of 9.2 [5.8-13.9] years. aHSCT was performed on 343 (20.6%) patients, half of whom have undergone the procedure after achieving 2nd or greater remission. …”
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Direct economic burden of acute coronary syndromes in the Portuguese National Health Service—facts and trends between 2002 and 2022 by Francisco Madeira, Carla Martins, Susana Viegas, Ana Teresa Timóteo, Ana Teresa Timóteo, Fátima Loureiro, Julian Perelman

“…As resources, we considered health professional working hours, non-medical resources used during in-patient stays, laboratory and diagnostic tests, interventional cardiology procedures, pharmaceuticals, hospitalization-related complications, rehabilitation services, and death costs. …”
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Surgical site infections following oral cavity cancer resection and reconstruction is a risk factor for plate exposure by Christopher M. Yao, Hedyeh Ziai, Gordon Tsang, Andrea Copeland, Dale Brown, Jonathan C. Irish, Ralph W. Gilbert, David P. Goldstein, Patrick J. Gullane, John R. de Almeida

“…Plate exposure may require multiple procedures to manage and occasionally free flap reconstruction.…”
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