Vesicouterine fistula with vesical calculi secondary to IUD migration: a case report by Yiyang Tian, Han Li, Xianhui Hu, Xiefeng Hu

“…This case is notable due to the absence of typical Youssef’s syndrome symptoms and the insidious presentation of a Type III VUF, complicating timely diagnosis. …”
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The Dilemma of Human Cloning in Islamic Theology: A Critique of the Uniqueness of Human Creation and Implications for Maqashid al-Shariah by Feni Khairifa, Endrise Septina Rawanoko, Indira Fatra Deni Peranginangin

“…This study aims to analyse the ethical and theological dilemmas of human cloning within the context of Islamic theology, with a particular focus on the challenges it poses to the principles of Maqashid al-Shariah. With increasing advancements in cloning technology, this research becomes crucial to identify the ethical and spiritual implications of creating genetically identical life forms. …”
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Primary cardiac diffuse large B-cell lymphoma patient: clinical, histologic, immunophenotypic feature and a novel surgical technology: a case report by Chenxi Ying, Weidong Li, Yu Zou, Bohao Dai, Xin Chen

“…Non-germinal center B-cell (non-GCB) diffuse large B-cell lymphoma (DLBCL), a subtype of PCL, often presents with severe symptoms due to its cardiac involvement, and poses diagnostic and therapeutic challenges. …”
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Recurrent giant retroperitoneal dedifferentiated liposarcoma requiring challenging multiorgan resection: a case report by Cesar Prugue, Emma Bao, Camden Pereira, Bing Yi

“…The tumor’s proximity to the abdominal aorta and invasion into the psoas muscle posed significant surgical challenges, requiring careful resection. …”
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An extralingual Ectomesenchymal chondromyxoid tumor with RREB1::MRTFB fusion: a rare case report of plantar fascia involvement by Yu Deng, Wei Liu, Ke Sun

“…Abstract Background Ectomesenchymal chondromyxoid tumor (ECT) is a rare benign intraoral tumor that almost exclusively presents as a small mass on the anterior dorsal tongue. …”
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Demographic Insights into One-Year Mortality Following Proximal Femur Fracture Surgery in India by Shivanshu Mittal, Vivek Kumar David

“…Introduction: Proximal femur fractures are a significant public health issue and a leading cause of morbidity and mortality in the elderly. It poses a remarkable burden on healthcare resources. …”
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Bipolar Disorder after COVID-19 Infection: A Case Report from an Ethiopian Perspective by Elias Tesfaye, Selamawit Alemayehu, Elias Gebru

“…Case Presentation. The patient presented with behavioral disturbance after a diagnosis of COVID-19. …”
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A rare case of adult ovarian inguinal hernia with an associated pelvic ectopic kidney by Komal Mishra, Pratapsingh Parihar, Rakshanda Agrawal

“…Ovarian inguinal hernia is an uncommon condition, particularly in adult females, and poses significant diagnostic challenges. This report details the case of a 40-year-old female presenting with a left-sided ovarian hernia, highlighting the clinical presentation, imaging findings, surgical management, and postoperative outcomes. …”
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Excellent Response to Trastuzumab Deruxtecan of a Large Medullary Metastasis from Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer: A Case Report by Aoi Kuroda, Mao Uematsu, Mai Shimura, Akira Hirota, Misao Fukuda, Nobuyuki Takahashi, Hiromichi Nakajima, Chikako Funasaka, Chihiro Kondoh, Kenichi Harano, Nobuaki Matsubara, Ako Hosono, Yoichi Naito, Toru Mukohara

“…Surgery was deemed infeasible because the lesion’s location and size posed high risks of toxicity from SRS. Promising intracranial responses to trastuzumab deruxtecan (T-DXd) have been reported; therefore, T-DXd was chosen. …”
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Successful Long-Term Treatment of Pediatric Relapsing Idiopathic Optic Neuritis with Mycophenolate Mofetil by Shuhei Fujino, Keiji Akamine, Eiichiro Noda, Sahoko Miyama

“…Corticosteroids are typically used for acute management; however, their prolonged use in children poses significant risks, including central obesity, hypertension, and growth impairment, underscoring the need for nonsteroidal, long-term treatment options. …”
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Management of an infectious complication appearing in a transcanine implant: a case report by Maxime Delarue, Pierre Klienkoff, Mélanie Le Ven, Fabien Bornert

“…But in the longer term an implant therapy is nevertheless indicated. Case presentation A 42-year-old man presented with persistent swelling and pain in the maxillary region associated with a transcanine implant placed one year ago by his dental practitioner. …”
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The enigmatic wandering spleen: managing three cases in a tertiary setting by Mohammed Al Blooshi, Abdalla Aboelkheir, Avinash Hiremath, Ghadir Jaber, Mamoun AlMarzouqi

“…In pediatric patients, this condition can present with vague abdominal symptoms or acute torsion leading to infarction, posing a significant diagnostic challenge. …”
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Breast cancer survival in a rural setting in the Busoga Region of Uganda by Rasmus Kallestrup, Katinka Bolette Lorentzen, John Mwayi, Joanita Mbabazi, Per Kallestrup, Troels Alnor Einarson

“…Abstract Background Breast cancer (BC) poses a significant health challenge globally. While high-income countries benefit from robust healthcare systems, sub-Saharan Africa (SSA) faces elevated BC mortality rates. …”
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Confronting Dual Therapeutic Hurdles in Advanced HIV: A Case Report on INSTIs Resistance and Talaromyces marneffei Coinfection by Zou L, Diao Y, Huang Z, You C

“…Lun Zou, Yuting Diao, Zhihao Huang, Chunfang You Department of Infectious Diseases, Zigong First People’s Hospital, Zigong, Sichuan, People’s Republic of ChinaCorrespondence: Chunfang You, Department of Infectious Diseases, Zigong First People’s Hospital, No. 42, Shangyihao Branch Road 1, Zigong, Sichuan, 643000, People’s Republic of China, Email 2421662719@qq.comBackground: Treating patients with human immunodeficiency virus (HIV) integrase strand transfer inhibitors (INSTIs) resistance and concurrent Talaromyces marneffei (T. marneffei) infection poses a significant clinical challenge, requiring precise antiretroviral adjustments, timely anti-infection, and management of complex drug interactions.Case Presentation: Interrupted antifungal therapy and INSTIs resistance in an HIV patient coinfected with T. marneffei resulted in severe immunosuppression. …”
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Internet generation in religious cyberspace: worldview challenges of the digital age by Ірина Ломачинська, Юлія Гришина

“…The relevance and novelty of the research consists in determining the specifics of the religious cyberspace func-tioning in the context of the spiritual and intellectual needs of the Internet generation, clarifying the essence of worldview challenges that the globalized digital age poses to young people in the religious cyberspace. …”
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Primary Cerebral Venous Thrombosis in a Patient with Immune Thrombocytopenic Purpura by M. Taher Farfouti, Christina Masri, Mike Ghabally, George Roumieh

“…Her past medical history was significant for immune thrombocytopenic purpura that was treated with prednisolone 40 mg per day which posed a therapeutic challenge. High-dose prednisolone and platelet transfusion were initiated; enoxaparin was administrated and switched to warfarin after stabilization of platelet count. …”
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Lactic acidosis in hemophagocytic syndrome: diagnostic and therapeutic challenges in the intensive care unit—a case series by Tianqi Xu, Ming Tang, Meiqing Wu, Xiaoyan Xue

“…Severe lactic acidosis (lactate ≥ 10 mmol/L), a rare yet critical manifestation, poses unique diagnostic and therapeutic challenges in the intensive care unit. …”
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Application of Nuclear Medicine Liver-Spleen Scan for Evaluation of Littoral Cell Angioma of the Spleen: A Case Report by Aren Dermarderosian BS, Raffi Boghossian, Derek Tai DO, Javid Sadjadi MD, Mojtaba Akhtari MD

“…This case highlights the diagnostic challenge posed by LCA due to its nonspecific clinical presentation and imaging findings. …”
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Polymyalgia rheumatica - risk factors, pathogenesis, diagnostic methods, treatment - new literature reports by Anita Warzocha, Anita Krowiak, Gabriela Majka, Piotr Pitrus, Karolina Krowiak, Magdalena Kowalczyk, Karol Bednarz, Maria Jasiewicz, Wiktoria Hander, Aleksandra Karnas

“…Summary Polymyalgia rheumatica continues to pose diagnostic and therapeutic challenges, particularly in patients with atypical presentations or treatment resistance. …”
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Enhanced prefrontal nicotinic signaling as evidence of active compensation in Alzheimer’s disease models by Saige K. Power, Sridevi Venkatesan, Sarah Qu, JoAnne McLaurin, Evelyn K. Lambe

“…We identified a significant and selective increase in post-synaptic nicotinic receptor signalling on prefrontal cortical neurons. …”
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