Case Report: “DEK::AFF2 fusion associated sinonasal carcinomas: a novel oncogenic driver and emerging therapeutic strategies” by Moritz Knebel, Moritz Knebel, Abbas Agaimy, Jan Philipp Kühn, Jan Philipp Kühn, Sandrina Körner, Sandrina Körner, Felix Braun, Felix Braun, Lukas Brust, Lukas Brust, Veronika Flockerzi, Veronika Flockerzi, Silke Wemmert, Silke Wemmert, Benedikt Balensiefer, Benedikt Balensiefer, Bernhard Schick, Umut Yilmaz, Umut Yilmaz, Malek Zaito, Malek Zaito, Alessandro Bozzato, Alessandro Bozzato, Maximilian Linxweiler, Maximilian Linxweiler

“…Recently classified by the WHO as a distinct provisional subtype of non-keratinizing squamous cell carcinoma, these tumors pose significant diagnostic and therapeutic challenges. …”
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Device Therapy in Patients with Heart Failure: Is Medication Use Optimized and Are We Targeting Those Patients Most Likely to Benefit? by Robert Wannamaker, MD, MSc, Roopinder K. Sandhu, MD, MPH, Justin A. Ezekowitz, MBBCh, MSc, Sheri L. Koshman, PharmD, Derek S. Chew, MD, MSc, Luke R. Gagnon, MD, MSc, Chen-Hsiang Ma, MD, Chandu Sadasivan, Gavin Y. Oudit, MD, PhD, Finlay A. McAlister, MD, MSc

“…Résultats: Parmi les 250 patients potentiellement admissibles à la pose d’un défibrillateur cardioverteur implantable (DCI) en prévention primaire, 136 (54,4 %) ont été orientés dans les 6 mois suivant l’instauration du TMOLD : 34 (25 %) appartenaient au groupe MADIT-ICD présentant le rapport risque-bénéfice le plus faible tandis que 6 (9,7 %) des patients non orientés appartenaient au groupe présentant le rapport risque-bénéfice le plus élevé. …”
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A comprehensive analysis of organochlorine pesticides in Egyptian waters: distribution, ecological impacts, and health risks by Samir Shamma, Mohamed Ali Hussein, Mahmoud Dawood, Eslam M. A. El-Nahrery, Ahmed Shahat, Mohamed N. Hegazy, Hani N. Sewilam, Tamer Shoeib, Anwar Abdelnaser

“…These present a potential long-term risk to human health and ecosystems. …”
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Understanding the Paradigm of Treatment Dropouts in Diabetic Retinopathy Care: A Prospective Cohort Study by Alisha Elizabeth Alex, Inchara Nagraj, Sangeetha, BS Narendran

“…Diabetic Retinopathy (DR) if left untreated can pose a serious risk to one’s vision and treatment dropouts pose a significant challenge. …”
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Computational insights in CD58 binding to ASFV CD2v and in silico optimization of nanobody designs against the interface by Albert Neil Gura Dulay, Richelle Mae Evasco Padilla, Nyzar Mabeth Obenio Odchimar, Fredmoore Legaspi Orosco

“…Results: Simulations report poor affinity of CD2v to CD58 in the "canonical" pose and present a novel pose backed by docking, simulation data, and recent observations. …”
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Plastic waste recycling for the production of graphene nanomaterials using electric arc discharge by M. K. Kazankapova, B. T. Yermagambet, Z. T. Dauletzhanova, A. Akshekina, A. B. Malgazhdarova, Z. M. Kassenova, A. K. Kolpek

“…Abstract The increasing global consumption of plastic products has resulted in a growing accumulation of plastic waste, posing severe environmental challenges. The study aims to explore methods for recycling plastic macaque waste to produce carbon nanomaterials. …”
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Cryptic Temporal Bone Fibrous Dysplasia with Predominant Vestibular Symptoms: A Case Report by kenechukwu Uche-Okonkwo, Moses Ayodele Akinola, John Ifeanyi Nwadiokwu, Oluwapelumi Olusoga-Peters, Babatunde Akinola Bamgboye

“…While symptoms such as aural fullness, tinnitus, and hearing loss are commonly reported, specific vestibular symptoms like vertigo and nystagmus are considerably less frequent.  Case Presentation: In this report, we describe the diagnostic features, management, and outcome of a 37-year-old Nigerian patient with fibrous dysplasia of the right temporal bone, who presented with recurrent debilitating vertigo, along with tinnitus and aural fullness, but without any obvious temporal bone deformity, which posed an initial diagnostic dilemma. …”
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Acute Traumatic Musculotendinous Avulsion of the Flexor Pollicis Longus Tendon Treated with Primary Flexor Digitorum Superficialis Transfer: A Novel Technique of Management by P. Kiran Sasi, Swagath Mahapatra, Samuel C. Raj Pallapati, Binu P. Thomas

“…Traumatic musculotendinous junction avulsions are rare injuries except in avulsion amputations. They pose a significant challenge to the treating surgeon. …”
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Isolated Gastric Myeloid Sarcoma: A Case Report and Review of the Literature by Pankit Vachhani, Prithviraj Bose

“…While extramedullary involvement in AML is uncommon in itself, isolated myeloid sarcomas, that is, myeloid sarcomas without any bone marrow involvement, are extremely rare and pose a diagnostic and therapeutic challenge. Here, we present the case of a middle-aged woman with isolated myeloid sarcoma in the stomach—an organ seldom involved by this disease. …”
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Does an Algorithm Replace Clinical and Sports Judgment in Exercise Prescription? by Jhony Jairo Cárdenas Garay, Carlos Alberto Romero Cuestas, Brian Johan Bustos Viviescas

“…Artificial intelligence presents itself as a facilitator of connections, but it is not, in fact, a facilitator of specialized knowledge spaces. …”
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IMPACT ASSESSMENT OF IMAGE FEATURE EXTRACTORS ON THE PERFORMANCE OF SLAM SYSTEMS by Taihú Pire, Thomas Fischer, Jan Faigl

“…This work evaluates an impact of image feature extractors on the performance of a visual SLAM method in terms of pose accuracy and computational requirements. In particular, the S-PTAM (Stereo Parallel Tracking and Mapping) method is considered as the visual SLAM framework for which both the feature detector and feature descriptor are parametrized. …”
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Isolated Jejunal Perforation and Mesentery Injury following a Kick on the Abdomen of a College Student: A Case Report from a District Hospital in Northern Ghana by Engelbert A. Nonterah, Solomon Atindama, Emmanuel Achumbowina, Michael B. Kaburise, Edwin Saanwie, Aziz Ewura, Majeedallahi Al-Hassan

“…Isolated jejunal perforation from blunt abdominal trauma is an extremely rare intra-abdominal injury that poses a huge diagnostic challenge. Delay in diagnosis and initiation of treatment often leads to significant morbidity and mortality. …”
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Outcomes of ventral hernia repair in patients of severe obesity: An experience from a tertiary care centre by Sonali Mittal, Arun Kumar, Jagadeep Ajmera, Surabhi Vyas, Sandeep Aggarwal

“…Introduction: Ventral hernia (VH) in patients with severe obesity poses a surgical challenge during bariatric surgery (BS). …”
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Pediatric cancer mortality: Analyzing early deaths and fatalities in a resource-limited tertiary care context. by Ahmed Farrag, Amira Mahmoud Osman, Mohamed Hamdy Ghazaly

“…<h4>Conclusions</h4>Delayed presentation leading to early deaths poses a significant obstacle to the successful treatment of childhood cancers. …”
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Enhancing Torrefaction Process Modeling with Data Augmentation: a Study on Agri-food Residues by Bartolomeo Cosenza, Michele Miccio, Ahmad Adeed Arshad

“…Agri-Food residues can pose environmental challenges, but through proper valorization, they can support circular economy principles by providing alternatives to fossil fuels. …”
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Humanitarian intervention and human rights by Alkhattab REEM

“…Humanitarian interventions are mechanisms aimed to protecting human rights and reducing suffering, yet they pose ethical challenges due to the use of lethal force and its resulting harm to civilians. …”
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Carotid-cavernous fistula caused by laceration of persistent fetal trigeminal artery treated with single catheter coil embolization by Benjamin L. Brown, Anthony H. Sin, Hugo H. Cuellar

“…We present the endovascular treatment of traumatic carotid-cavernous fistula from persistent fetal trigeminal artery (PFTA) laceration. …”
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2019–2020 Florida Citrus Production Guide: Nematodes by Larry W. Duncan, Joe W. Noling, Renato N. Inserra

“…Similarly, some management methods pose risks to people and the environment, and therefore it is important to know that their use is justified by the actual conditions in a grove. …”
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Resilient DNN for joint sub-band allocation and power control in mobile factory subnetworks by Saeed Hakimi, Ramoni Adeogun, Gilberto Berardinelli

“…Abstract In industrial wireless communication environments, the complexity and rapid dynamics of mobile factory subnetworks pose substantial challenges for radio resource management. …”
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Driving into the Sunset: Supporting Cognitive Functioning in Older Drivers by Mark S. Young, David Bunce

“…The rise in the aging driver population presents society with a significant challenge—how to maintain safety and mobility on the roads. …”
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