Spectrum and epidemiology of rare diseases in a Chinese natural population of 14.31 million residents, 2012–2023 by Ming-Jia Li, Qi Li, Miao-Miao Zhao, Hanna Kim, Ruo-Qi Feng, Mo-Ning Guo, Jian-Peng heng, Jin-Kui Yang, Chang Liu

“…These findings underscore the critical need for healthcare policies that address the unique challenges posed by rare diseases in China.…”
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Landslide Detection in Long-Term and Low-Coherence Scenario Using Faster Intermittent Stacking InSAR Method by Huayan Dai, Lixin Wu, Yunping Liao, Lichuan Chen, Yong Yang

“…This often leads to the minimal capability of conventional time-series InSAR methods, which poses challenges for effective ground deformation detection, particularly in low-coherence areas over long-term scenarios. …”
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Prevalence of strongyloidiasis in immunocompromised patients in Mazandaran province of northern Iran: A comprehensive study utilizing simultaneous parasitological, serological, and... by Reza Saberi, Aliasghar Ghorbanzadeh, Rabeeh Tabaripour, Shahabeddin Sarvi, Shirzad Gholami, Seyed Abdollah Hosseini

“…This intestinal nematode poses significant health risks, particularly in immunocompromised individuals. …”
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Hepatoprotective effects of Curcuma xanthorrhiza Roxb. extract via free radical scavenger, inhibiting apoptosis and inflammation mechanisms in acetaminophen-induced liver injury by I Nyoman Lister, Linda Chiuman, Maya Mutia, Hartono Hartono, Ermi Girsang, Annisa Sutendi, Hanna Kusuma, Dhanar Hadiprasetyo, Wahyu Widowati

“…Objective(s): Acetaminophen (APAP)-mediated liver injury poses a significant public health concern. Curcuma xanthorrhiza extract (CXE) has been traditionally used for its hepatoprotective properties. …”
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Case Report: Whole genome sequencing identifies a novel deep intronic COL4A5 variant of uncertain significance in X-linked Alport syndrome by Hoon Seok Kim, Hoon Seok Kim, Myungshin Kim, Myungshin Kim, Jin-Soon Suh, Yeonhee Lee

“…Here, we report the case of a 4-year-old boy who presented with persistent microscopic hematuria detected during routine urinalysis. …”
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Phycomediation of cadmium contaminated aqueous solutions using Chlamydomonas sp.: process optimization and adsorption characterization by Reem Mohammed Alharbi, Neveen Abdel-Raouf, Neveen Abdel-Raouf, Mostafa Shaaban Mohamed, Wael A. Fathy, Ibraheem Borie M. Ibraheem, Walaa Gamal Hozayen

“…The contamination resulting from heavy metals present in industrial effluents represents a critical global challenge, posing profound risks to aquatic ecosystems and human health. …”
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A novel and secure artificial intelligence enabled zero trust intrusion detection in industrial internet of things architecture by Asif Ali Laghari, Abdullah Ayub Khan, Amel Ksibi, Fahima Hajjej, Natalia Kryvinska, Ahmad Almadhor, Mohamad Afendee Mohamed, Shtwai Alsubai

“…One of the major problems that arises as a malevolent possibility is cybercrime, which poses a threat to governments, corporations, and societies—most significantly, civil society. …”
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AN ADVANCED MACHINE LEARNING (ML) ARCHITECTURE FOR HEART DISEASE DETECTION, PREDICTION AND CLASSIFICATION USING MACHINE LEARNING by Muhammad Anas, Muhammad Atif Imtiaz, Saad Khan, Arshad Ali, Noor Fatima Naghman, Hamayun Khan, Sami Albouq

“…Some of these techniques do not easily diagnose heart diseases at early stages hence, getting treatment late poses a big risk. The present work attempts to better predict this disease from the chest pain symptom, and classify it by designing an efficient machine learning system based on a dataset with 303 patient data made available to the public domain. …”
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Multidrug-Resistant Infections and Metabolic Syndrome: An Overlooked Bidirectional Relationship by Carlo Acierno, Riccardo Nevola, Fannia Barletta, Luca Rinaldi, Ferdinando Carlo Sasso, Luigi Elio Adinolfi, Alfredo Caturano

“…Although current data remain largely associative and fragmented, the emerging MetS–MDR syndemic model poses substantial challenges for translational research, antimicrobial stewardship, and personalized therapeutic strategies. …”
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Effects of Antibiotic Residues on Fecal Microbiota Composition and Antimicrobial Resistance Gene Profiles in Cattle from Northwestern China by Wei He, Xiaoming Wang, Yuying Cao, Cong Liu, Zihui Qin, Yang Zuo, Yiming Li, Fang Tang, Jianjun Dai, Shaolin Wang, Feng Xue

“…Metagenomic sequencing revealed that carbapenemase-resistant genes (<i>bla</i>_KPC and <i>bla</i>_VIM) were also present in considerable abundance, accounting for about 10% of the total ARGs detected in three provinces. …”
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Comparative transcriptomic analysis reveals the important role of hepatic fatty acid metabolism in the acute heat stress response in chickens by Zi Mei, Zhenquan Song, Haobo Zhou, Bin Zheng, Yiwei Xiong, Zheya Sheng, Yanzhang Gong

“…Abstract Background Heat stress poses a major challenge to global poultry production, but the molecular mechanisms driving the acute heat stress response in multiple organs of chickens remain poorly understood. …”
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Trophic transfer of arsenic in the food chain from selected crops grown in long-term wastewater contaminated soil by Mudasra Munir, Kafeel Ahmad, Zafar Iqbal Khan, Shahzad Akhtar, Muhammad Nadeem, Asma Ashfaq, Mohammad Faisal, Abdulrahman A. Alatar, Hafiza Mamona Nazir, Ifra Saleem Malik

“…The study revealed a target hazard quotient (THQ) exceeding 2 at several sites, posing potential health risks. Leafy vegetables irrigated with wastewater accumulated arsenic above permissible limits due to soil contamination. …”
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Specific Detection of African Swine Fever Virus Variants: Novel Quadplex Real-Time PCR Assay with Internal Control by Lihua Wang, Yuzhen Li, Xirui Zhang, Rachel Madera, Homer Pantua, Aidan Craig, Nina Muro, Danqin Li, Jamie Retallick, Franco Matias Ferreyra, Quang Lam Truong, Lan Thi Nguyen, Jishu Shi

“…The emergence of ASF virus (ASFV) variants with varying genomic deletions poses significant challenges for ASF control. This study presents a novel, sensitive, and reliable quadplex real-time PCR assay for detecting ASFV variants lacking key genes (<i>I177L</i>, <i>EP402R</i>, and <i>MGF360-14L</i>), either individually or in combination. …”
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The value of prealbumin in predicting post hepatectomy liver failure for patients with hepatocellular carcinoma undergoing major hepatectomy by Hang-Dong Jia, Zhe-Jin Shi, Jian-Yong Yuan, Kai Wang, Yang Yu, Zheng-Kang Fang, Kai-Di Wang, Yi Lu, Guo-Liang Shen, Cheng-Wu Zhang, Lei Liang

“…Abstract Post hepatectomy liver failure (PHLF) poses a significant threat to the prognosis of patients with hepatocellular carcinoma (HCC), particularly those undergoing major hepatectomy. …”
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Model systems for emulating human tissue and physiology in psychiatric research by Kai Cheng, Anannya Kshirsagar, John Nixon, Jonathan Lau, Kun Yang, Akira Sawa, Annie Kathuria, Annie Kathuria

“…The modeling of psychiatric disorders poses significant challenges due to the complex nature of these conditions, which encompass a range of neuropsychiatric diseases such as autism spectrum disorder (ASD), schizophrenia (SCZ), bipolar disorder (BD), post-traumatic stress disorder (PTSD), anxiety disorder (AD) and depression. …”
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Identification of novel variants in carbamoyl phosphate synthetase 1 gene and comparative pathogenicity assessments of CPS1 missense variants following ACMG/AMP-ClinGen recommendat... by Fei Li, Qin Cai, Wei Ji, Miao Xu, Guoli Tian, Fanyi Zeng

“…Since the employment of genetic testing as a clinical diagnostic tool, distinguishing pathogenic from polymorphic changes poses significant problems for geneticists. As recommendation for PP3/BP4, the computational tools for missense variant have been published, we performed a comparative evaluation for pathogenicity interpretation in our patients and in ClinVar database regarding CPS1 missense variants under the updated guidelines of ACMG/AMP-ClinGen. …”
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Eco-friendly approach to corrosion inhibition of aluminum by Congo red dye in alkaline media: Experimental assessment, QSAR modeling, diffusion studies, and DFT/MC/MD simulations by Ayoub Chahid, Said Meftah, Mohamed Essahli, Mohammed Chafi, Rachid Kellal, Driss Benmessaoud Left, Mustapha Zertoubi

“…Aluminum corrosion in alkaline media poses a significant limitation for its industrial use. …”
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Prevalence of bacterial contamination on wild meat processing and cooking surfaces in rural Cameroon by Sara M. Soto, Laura Castellsagués, Victoria Ballén, Yaiza Gabasa, Pedro Mayor, Guillermo Ros Brull, Stephan M. Funk, Julia E. Fa

“…The transmission of food-borne pathogens from wildlife to humans presents a significant public health challenge. The recent COVID-19 pandemic has highlighted the critical need to enhance our understanding of wild animals' role in transmitting infectious diseases. …”
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Modern radiation-hygienic state of the territories of the Globus-4 and Gorizont-1 peaceful nuclear explosions in the Komi Republic by A. M. Biblin, K. V. Varfolomeeva, K. A. Sednev, S. A. Ivanov, V. S. Repin, A. G. Georgieva

“…The article presents results of a study of the radiation environment on territories adjacent to the sites of the “Globus-4” and “Gorizont-1” peaceful nuclear explosions in the Komi Republic. …”
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A phage-displayed nanobody-based competitive immunoassay for the detection of African swine fever virus antibodies by Wenting Chen, Jifei Yang, Qingli Niu, Jinming Wang, Yanghe Liu, Xuesai Li, Yaru Zhao, Zhonghui Zhang, Zhijie Liu, Guiquan Guan, Hong Yin

“…Abstract African swine fever (ASF) is a highly infectious and devastating disease that poses a significant threat to the global swine industry. …”
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