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2661
Integrative machine learning and molecular simulation approaches identify GSK3β inhibitors for neurodegenerative disease therapy
Published 2025-07-01“…Abstract Neurodegenerative diseases (NDDs), including Alzheimer’s disease (AD) and Parkinson’s disease (PD), are a growing global health concern, especially among the elderly, posing significant challenges to well-being and survival. …”
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2662
Detection of Aflatoxin B1 in Maize Silage Based on Hyperspectral Imaging Technology
Published 2025-05-01“…Aflatoxin B1 (AFB1) is widely present in maize silage feed and poses strong toxicity, seriously threatening livestock production and food safety. …”
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2663
ENGLISH VERSION: AGE FEATURES OF RADIOACTIVE IODINE (131I) ABSORPTION BY RAT THYROID GLANDS IN CORRECTION OF THE DIETARY IODINE DEFICIENCY WITH ORGANIC IODINE
Published 2021-04-01“…The insufficient efficacy of inorganic iodine drugs poses the problem of search for new means for iodine deficiency treatment and prevention. …”
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2664
Predicting emotional responses in interactive art using Random Forests: a model grounded in enactive aesthetics
Published 2025-08-01“…However, these emotional responses’ inherently dynamic, subjective, and often pre-reflective nature poses significant challenges to their systematic prediction and computational modeling.MethodsTo address these challenges, the present study introduces an interpretable machine learning framework grounded in the Random Forest (RF) algorithm, which provides a balanced trade-off between predictive performance and model transparency, thereby aligning with the needs of theory-driven emotion research. …”
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2665
Abstract 212: Percutaneous Carotid access in Mechanical Thrombectomy ‐ a safe alternative to transfemoral approach
Published 2023-11-01“…Methods 75‐year‐old left‐handed functional male (mRs:0) with past medical history of HTN, HLD presented to ED after being found on the floor by his family with slurred speech, new onset right sided weakness, with a last known well of 17 hours. …”
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2666
Epidemic Keratoconjunctivitis: A Growing Concern in Pakistan
Published 2024-07-01“…While EKC is typically a self-limiting condition with a relatively low risk of severe complications, corneal involvement poses a concern. Within the first week of adenoviral conjunctivitis, individuals may experience the onset of punctate or geographic epithelial keratitis. …”
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2667
CrysMTM: a multiphase, temperature-resolved, multimodal dataset for crystalline materials
Published 2025-01-01“…We present CrysMTM, a large-scale, multimodal dataset designed to benchmark temperature- and phase-sensitive machine learning models for crystalline materials. …”
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2668
A Digital Shadow for Modeling, Studying and Preventing Urban Crime
Published 2025-01-01“…This paper presents the development and validation of a digital shadow platform for macro-modeling and simulating urban crime. …”
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2669
Targeting ESKAPE pathogens with ZnS and Au@ZnS Core–Shell nanoconjugates for improved biofilm control
Published 2025-07-01“…This research highlights the potential of Au@ZnS nanoconjugates to revolutionize infection control on medical devices and implants, offering a promising solution to the global healthcare challenge posed by biofilm-forming pathogens as we also observed minimal bacterial colonization on Au@ZnS treated urinary catheters.…”
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2670
Characterization of Field of View in Visible Light Communication Systems for Intelligent Transportation Systems
Published 2020-01-01“…Despite the implementation of long-sought ITS protocols poses the crucial need to detail how the features of optical stages influence the overall performances of a VLC system in realistic configurations, such characterization has rarely been addressed at present. …”
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2671
Evaluating trauma severity scores: Predicting mortality in patients with geriatric trauma
Published 2025-06-01“…Abstract Background Trauma in older adults poses distinct challenges due to age‐related physiology changes, increased comorbidities, and diminished physiological reserves. …”
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2672
D-optimal candexch algorithm-enhanced machine learning UV-spectrophotometry for five-analyte determination in novel anti-glaucoma formulations and ocular fluids: four-color sustain...
Published 2025-07-01“…Abstract The novel anti-glaucoma ophthalmic preparation containing latanoprost, netarsudil, and benzalkonium chloride has posed a significant challenge due to its complexity and the lack of environmentally sustainable quantification methods, with only a single published method available for its quantification that lacks environmental consideration. …”
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2673
LNT-YOLO: A Lightweight Nighttime Traffic Light Detection Model
Published 2025-06-01“…Traffic light detection systems, as a key part of autonomous vehicles, play a key role in navigation during challenging traffic scenarios. Nighttime driving poses significant challenges for autonomous vehicle navigation, particularly in regard to the accuracy of traffic lights detection (TLD) systems. …”
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2674
Development of a candidate mRNA vaccine based on Multi-Peptide targeting VP4 of rotavirus A: an immunoinformatics and molecular dynamics approach
Published 2025-07-01“…With significant morbidity and mortality, this pathogen poses a serious global health challenge, particularly in underdeveloped countries. …”
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2675
Wearable device-based interventions in heat-exposed outdoor workers — a scoping review and an explanatory intervention model
Published 2025-08-01“…Abstract Background Global climate change poses a challenge to the health prevention of heat-exposed outdoor workers. …”
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2676
Attapulgite/oyster shell composite reduces cadmium and lead bioavailability in acidic agricultural soils through synergistic adsorption and pH regulation
Published 2025-05-01“…Abstract Heavy metal contamination in acidified agricultural soils poses significant environmental and health risks. …”
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2677
An Optimal Internet of Things-Driven Intelligent Decision-Making System for Real-Time Fishpond Water Quality Monitoring and Species Survival
Published 2024-12-01“…This study marks a significant step forward in climate-smart aquaculture, contributing to enhanced fish health, survival, and yield while mitigating the risks posed by climate change on aquatic ecosystems.…”
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2678
Use of agroindustrial wastes as pozzolanic materials in cementitious systems: A review
Published 2025-07-01“…Additionally, solid waste management poses a major challenge for society, given the diversity and quantity of waste, as well as population growth and consumption trends. …”
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2679
N‐methylation of histidine to tune tautomeric preferences in histidine‐heme coordination and enzyme‐mimetic catalysis
Published 2024-09-01“…However, evaluating the impact of Nδ and Nε is difficult, and directly integrating noncanonical N‐methylated histidine within enzymes poses risks due to laborious procedures. In this study, we present the self‐assembly of Fmoc‐Histidine (Fmoc‐His) with hemin to create a peroxidase‐mimetic catalyst, in which either the Nε or Nδ of histidine is methylated to modify the tautomeric preferences, thereby tuning hemin catalysis. …”
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2680
YOLOv8-Scm: an improved model for citrus fruit sunburn identification and classification in complex natural scenes
Published 2025-07-01“…In recent years, global warming has intensified extreme weather events, such as prolonged high temperature and strong solar radiation, posing increasing risks to citrus production,leading to significant economic losses. …”
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