Comparative transcriptomic analysis reveals the important role of hepatic fatty acid metabolism in the acute heat stress response in chickens by Zi Mei, Zhenquan Song, Haobo Zhou, Bin Zheng, Yiwei Xiong, Zheya Sheng, Yanzhang Gong

“…Abstract Background Heat stress poses a major challenge to global poultry production, but the molecular mechanisms driving the acute heat stress response in multiple organs of chickens remain poorly understood. …”
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Specific Detection of African Swine Fever Virus Variants: Novel Quadplex Real-Time PCR Assay with Internal Control by Lihua Wang, Yuzhen Li, Xirui Zhang, Rachel Madera, Homer Pantua, Aidan Craig, Nina Muro, Danqin Li, Jamie Retallick, Franco Matias Ferreyra, Quang Lam Truong, Lan Thi Nguyen, Jishu Shi

“…The emergence of ASF virus (ASFV) variants with varying genomic deletions poses significant challenges for ASF control. This study presents a novel, sensitive, and reliable quadplex real-time PCR assay for detecting ASFV variants lacking key genes (<i>I177L</i>, <i>EP402R</i>, and <i>MGF360-14L</i>), either individually or in combination. …”
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Identification of novel variants in carbamoyl phosphate synthetase 1 gene and comparative pathogenicity assessments of CPS1 missense variants following ACMG/AMP-ClinGen recommendat... by Fei Li, Qin Cai, Wei Ji, Miao Xu, Guoli Tian, Fanyi Zeng

“…Since the employment of genetic testing as a clinical diagnostic tool, distinguishing pathogenic from polymorphic changes poses significant problems for geneticists. As recommendation for PP3/BP4, the computational tools for missense variant have been published, we performed a comparative evaluation for pathogenicity interpretation in our patients and in ClinVar database regarding CPS1 missense variants under the updated guidelines of ACMG/AMP-ClinGen. …”
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Eco-friendly approach to corrosion inhibition of aluminum by Congo red dye in alkaline media: Experimental assessment, QSAR modeling, diffusion studies, and DFT/MC/MD simulations by Ayoub Chahid, Said Meftah, Mohamed Essahli, Mohammed Chafi, Rachid Kellal, Driss Benmessaoud Left, Mustapha Zertoubi

“…Aluminum corrosion in alkaline media poses a significant limitation for its industrial use. …”
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A novel protein encoded by circUBE2G1 suppresses glycolysis in gastric cancer through binding to ENO1 by Lu Lu, Guoqing Guo, Jiahao Guo, Hanyang Li, Kexin Chen, Yuli Chen, Qiuhui Li, Qiunuo Li, Yuhao Diao, Ming Sun, Hao Wu, Xianghua Liu

“…Abstract Gastric cancer (GC), a malignant neoplasm originating in the stomach epithelium, is characterized by substantial global incidence and mortality rates, posing a substantial threat to public health systems worldwide. …”
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Whole genome sequence analysis reveals limited diversity among Clostridioides difficile ribotype 027 and 078 isolates collected in 22 hospitals in Berlin and Brandenburg, Germany by Esther E. Dirks, Vanessa Pfiffer, Genevieve Sohl, Fabian K. Berger, Ina Friesen, Johannes Friesen, Ralf Ignatius, Johannes Elias, Alexander Mellmann, Mardjan Arvand

“…Ribotype (RT) 027 poses a particular risk due to its proposed “hypervirulence”. …”
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Enhancing the Drug Release and Physicochemical Properties of Rivaroxaban via Cyclodextrin Complexation: A Comprehensive Analytical Approach by Cristina Solomon, Valentina Anuța, Iulian Sarbu, Emma Adriana Ozon, Adina Magdalena Musuc, Veronica Bratan, Adriana Rusu, Vasile-Adrian Surdu, Cătălin Croitoru, Abhay Chandak, Roxana Mariuca Gavriloaia, Teodora Dalila Balaci, Denisa Teodora Niță, Mirela Adriana Mitu

“…<b>Background/Objectives</b>: Rivaroxaban, an oral anticoagulant, shows poor aqueous solubility, posing significant challenges to its bioavailability and therapeutic efficiency. …”
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Epidemiology, Transmission, and Evolution of Japanese Encephalitis Virus by Chengcheng Peng, Huiling Qin, Fan Yu, Yujia Hao, Yuge Yuan, Wenzhou Ma, Duo Zhang, Pengpeng Xiao, Nan Li

“…The Japanese encephalitis virus is an arbovirus that causes severe damage to the central nervous system. At present, there are still 67,900 cases of Japanese encephalitis worldwide every year, which poses a global public health concern and causes great economic losses to animal husbandry. …”
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Coexistence of bla NDM-1, mcr-1 and bla CTX-M-199 in an ST499 multidrug resistant Klebsiella pneumoniae Isolate by Xinjun Hu, Bingyou Yin, Ruishan Liu, Lu Gong, Xiaolu Yang, Zhenghao Lou, Haowei Ye, Bingyang Shang, Yibing Shang, Yingjian Zhang

“…Enhanced surveillance and targeted interventions are essential to manage the public health risks posed by multidrug-resistant strains.…”
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Short‐Term Effects of Folate Supplementation in Combination With Vitamin B6 for Treating Acute Manic Episodes in Bipolar I Disorder: A Randomized Controlled Trial by Farzad Akbarzadeh, Andisheh Talaei, Mohsen Nematy, Dina Ganji, Alireza Ebrahimi, Ali Talaei

“…ABSTRACT Background Drug resistance poses a formidable challenge in managing acute manic episodes in bipolar I disorder, leading to suboptimal treatment outcomes. …”
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Use of an anatomical atlas in real-time EIT reconstructions of ventilation and pulsatile perfusion in preterm infants by Christopher J. Rocheleau, Trevor D. Overton, Nilton Barbosa da Rosa, Gary J. Saulnier, Omid Rajabi Shishvan, Christopher D. Baker, Katelyn G. Enzer, Jennifer L. Mueller

“…Due to the severe ill-posedness of the inverse problem, good spatial resolution poses a challenge in EIT. Conversely, the temporal resolution is high, facilitating dynamic bedside imaging. …”
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Exploring the Antifibrotic Mechanisms of Ghrelin: Modulating TGF-β Signalling in Organ Fibrosis by Mei Li, Chang Zheng, Huiyi Wang, Shan Wang

“…This imbalance can lead to compromised organ function and potential failure, posing significant health risks. The condition’s complexity necessitates the exploration of effective treatments to mitigate its progression and adverse outcomes. …”
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Production of Bioproducts from Wastewater Treatment Using the Microalga Neochloris oleoabundans by Fahd Mnasser, Mª Lourdes Martínez‐Cartas, Sebastián Sánchez

“…ABSTRACT Olive mill wastewater (OMW) poses an environmental risk due to its high chemical oxygen demand (COD). …”
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Life cycle environmental impacts and costs of water electrolysis technologies for green hydrogen production in the future by Jan Christian Koj, Petra Zapp, Christoph Wieland, Klaus Görner, Wilhelm Kuckshinrichs

“…Conclusions A unique combination of possible technological, environmental, and economic developments in the production of green hydrogen up to the year 2045 was presented. Based on a comprehensive literature review, several research gaps, such as a combined comparison of all three technologies by LCA and LCC, were identified, and research questions were posed and answered. …”
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Identification and direction of changes in work-life balance dimensions in Visegrad Group countries by Marta Domagalska Grędys, Adam Sagan, Katarzyna Piecuch

“… Objective: The article aimed to identify the dimensions and trajectories of work-life balance (WLB) across the Visegrad Group (V4) countries (Poland, the Czech Republic, Slovakia, and Hungary) during the period 2008-2022. We posed two research questions: which factors are most responsible for WLB and how do the dimensions of WLB evolve over time among the V4 countries? …”
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Potato Peels Waste Extract as Natural Antioxidant and Antimicrobial in Lemon Carbonated Soft Drink by Mohamed Mahmoud Helal, Tarek Ahmed El-Adawy, Alaa Ahmed El-Beltagy, Aboelfateh Abdelkader El-Bedawey, Saad Michael Youssef

“…Deterioration of these products by undesirable microorganisms can alter the sensory quality of the product which also poses a major public health risk. The soft drink category with lemon made up 85% of all bacterial contamination and was considered microbiologically unsafe due to a lack of preservatives. …”
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High tibial osteotomy in geriatric patients with gonarthrosis by Bedrettin Akar, Yusuf Oztürkmen, Mehmet B. Balioglu, Fatih Ugur, Erhan Sükür

“…In cases where radiological imaging posed difficulties in evaluation, classification was performed using magnetic resonance imaging. …”
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Mortality from acute types of coronary artery disease in men and women in Russia in 2015 and 2019 by I. V. Samorodskaya, M. G. Bubnova, O. A. Akulova, I. F. Matveeva

“…Greater regional variability in mortality, especially for other acute CAD types, poses the problem of finding organizational, methodological and strategic solutions to clarify the criteria for coding and refine the logistics schemes for providing healthcare for doubtful or uncertain diagnostic signs of acute CAD.…”
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Epidemiology and healthcare access inequities in diabetic foot disease: a retrospective study in Central Queensland, Australia by Michael Kirk, Gulam Khandaker, Yudish Kumar Soonarane, Ruth Varrall

“…Healthcare delivery has been shown to present significant challenges in rural and regional settings with Central Queensland being a large geographic area with limited local healthcare resources. …”
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Quantifying inter-dwelling air exchanges during fan pressurisation tests by David Glew, Felix Thomas, Dominic Miles-Shenton, James Parker

“…Not accounting for inter-dwelling air exchanges poses a risk of under-ventilation and misclassification of homes deemed suitable for natural ventilation. …”
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