High-Dose Inhaled Nitric Oxide as Adjunct Therapy in Cystic Fibrosis Targeting Burkholderia multivorans by Bethany L. Bartley, Kelly J. Gardner, Stefano Spina, Bryan P. Hurley, David Campeau, Lorenzo Berra, Lael M. Yonker, Ryan W. Carroll

“…Case Presentation. Here, we present the case of a 16-year-old female with CF who experienced a precipitous decline in lung function over the prior year in conjunction with worsening antibiotic resistance of her primary pathogen, Burkholderia multivorans. …”
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An ultrasound-guided modified iliac fascia and sacral plexus block application in a critically ill patient undergoing artificial femoral head replacement surgery: a case report by Muyan Shi, Ping Huang, Jie Tian, Ruixin Lin, Xiaoqiang Wang, Qiuyue Lian, Diansan Su, Zhenling Huang

“…The burgeoning aging population has exacerbated this issue, leading to a rise in the number of hip fracture cases coupled with concomitant geriatric ailments. Therefore, it poses a huge challenge to anesthesiologists with the increasing number of critically ill patients who are not suitable for general anesthesia and intrathecal anesthesia. …”
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Plant-based traditional remedies and their role in public health: ethnomedicinal perspectives for a growing population by Xueqin Wang, Tauseef Anwar, Huma Qureshi, Hossam S. El-Beltagi, Zobia Sehar, Dilafruz Solieva, Bakhrom Azizov, Nazih Y. Rebouh, Mehraj A. Abbasov, Farrukh Yakubov, Maryam M. Alomran

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Case Report: A rare case of coronary artery anomaly (right coronary artery-pulmonary artery fistula with diffuse dilatation) by Xiaoming Wang, Jie Yu, Changzheng Chen, Zhihua Yang, Lixia Yang

“…In addition, the treatment options for CAAs vary depending on the type and severity of the anomaly, posing further therapeutic challenges for healthcare providers.Case presentationThis case report describes a 39-year-old male presenting with heart failure secondary to a giant right coronary artery-pulmonary artery fistula (RCA-PA fistula) accompanied by diffuse aneurysmal dilatation. …”
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Follicular Lymphoma of the Gallbladder in an Octogenarian: A Case Report and Literature Review by Mikayla Myers MD, Bassel Dakkak MD, Swapna Sirigireddy MD, Ibrahim Shanti MD, Drew Ferguson MD, Abdelwahap Elghezewi MD, Mustafa Ben Khayal MD, Zakaria Alagha MD, MSc, Ahmed Sherif MD, AGAF, FASGE, Eva-Pattont Tackett MD, FACP

“…Herein, we present the case of an 82-year-old male who presented with acute abdominal pain and unintentional weight loss. …”
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Expanding Treatment Horizons with Chemical Agents and Drug Adjuvants in Odontogenic Keratocyst: A Comprehensive Review by Nidhi Vijaykumar Bodiwala, Nitin D Bhola, Chetan S Gupta

“…The scope of this review extends beyond conventional treatments, addressing the nuances of OKC from molecular and genetic perspectives to the challenges posed by its anatomical location. By providing a comprehensive resource for clinicians, researchers, and dental healthcare professionals, the present review aimed to contribute to the evolving understanding of OKC, guiding future research endeavours and enhancing the clinical management of this intriguing odontogenic lesion.…”
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Anaesthetic management of twin pregnancy with complete heart block: A continuing dilemma by Anju Rani, Alka Dahiya, Sudha Puhal, Vasudha Govil, Ritu Baloda, Sudhir Bisherwal

“…Background: Complete heart block (CHB) during pregnancy poses significant anesthetic challenges, particularly when associated with bradycardia, and in the absence of established perioperative management guidelines. …”
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Carbon Hollow Fiber Penetration Electrode with Unsaturated Ni‐N2 Coordination for Enhanced CO2 Electroreduction by Xiaotong Wang, Yiheng Wei, Yanfang Song, Jianing Mao, Xiaohu Liu, Shoujie Li, Guihua Li, Huanyi Zhu, Jiayu Xia, Cheng Luo, Aohui Chen, Xiao Dong, Wei Wei, Wei Chen

“…Abstract Hollow fiber gas penetration electrodes with a compact hierarchical pore structure have emerged as promising platforms for CO2 electroreduction. …”
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Drinking water access and quality in the Gaza Strip prior to 7 October 2023 and implications for reconstruction by Curdin Brugger, Branwen Nia Owen, Bassam Abu Hamad, Tammo van Gastel, Federico Sittaro, Rodolfo Rossi, Nicole Probst-Hensch, Mirko S. Winkler

“…Conclusions The water quality and insecurity about accessibility and quality of water pose a health threat and need to be addressed at system level. …”
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Digitising wound care: a cost-consequence analysis of the Wound Care Command Centre™ in Australia by Michelle Barakat-Johnson, Meg Newton, Crispin Cayley, Michelle Lai, Laura Dixie, Nathaniel Alexander, Marc Pelusi, Jimmy Chan, Anna Cohen

“…Abstract Background Chronic wounds pose considerable financial challenges for healthcare systems globally, with most cases requiring hospital care and extended lengths of stay, particularly due to delayed access to treatment. …”
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Clinical characteristics of and diagnostic approaches to human Francisella tularensis infection: a retrospective, monocentric case study from Germany by Sophie E. Müller, Sophie Schneitler, Sabine Zange, Maximilian Linxweiler, Arne Simon, Lorenz Thurner, Sören L. Becker

“…Francisella tularensis, the causative agent of tularemia, poses a challenge for diagnosis and treatment due to its diverse clinical presentations and low incidence. …”
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Emerging frontiers in epigenetic-targeted therapeutics for pediatric neuroblastoma by Xiaokang Wang, Gengrui Xu, Hongyan Ma, Xiaoyan Deng, Guiping Ma

“…Neuroblastoma (NB), the most prevalent extracranial solid malignancy in children, poses significant therapeutic challenges, particularly concerning high-risk subtypes characterized by an immunologically “cold” phenotype. …”
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Guided Bone Regeneration Using a Modified Occlusive Barrier with a Window: A Case Report by Luis Leiva-Gea, Alfonso Lendínez-Jurado, Paulino Sánchez-Palomino, Bendición Delgado-Ramos, María Daniela Corte-Torres, Isabel Leiva-Gea, Antonio Leiva-Gea

“…Background: Bone resorption following tooth loss poses significant challenges for dental implant success. …”
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Clinical and sociodemographic aspects of inflammatory bowel disease patients by Meenakshi Gururani, Joshi SC, Arun Joshi, Aishwary Bajpai

“…Data on demographic details, clinical presentation, laboratory findings, and treatment were collected and analyzed using SPSS. …”
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The Effectiveness of Teaching Spiritual Concepts Based on Mention and Prayer on Moral Intelligence and Quality of Attachment in Students by سارا آقابابایی, Fateme Hekmatzade

“…The research method was quasi-experimental with a pre-test, post-test, and follow-up design (for a period of 3 months) with a control group. …”
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Monolayer graphene/platinum-modified 3D origami microfluidic paper-based biosensor for smartphone-assisted biomarkers detection by Arda Fridua Putra, Annisa Septyana Ningrum, Suyanto Suyanto, Vania Mitha Pratiwi, Muhammad Yusuf Hakim Widianto, Irkham Irkham, Wulan Tri Wahyuni, Isnaini Rahmawati, Fu-Ming Wang, Chi-Hsien Huang, Ruri Agung Wahyuono

“…Conclusion: The 3D origami structure facilitates efficient fluid handling and multiplex detection, while the nanocatalyst modification improves pore infiltration and sensitivity. This work demonstrates, for the first time, a cost-effective, portable, and high-performance biosensor for dual biomarker detection, offering substantial promise for point-of-care diagnostics in neurological and metabolic health monitoring.   …”
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Single cell analysis of diverse immune cell in pneumococcal meningitis by Yujie Zhang, Jing Duan, Sufang Lin, Jialun Wen, Jianxiang Liao

“…Abstract Streptococcus pneumoniae, a Gram-positive, human-specific commensal infectious pathogen, poses a significant global health threat, especially in children under five, often resulting in fatalities. …”
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Biventricular arrhythmogenic cardiomyopathy and sudden cardiac death: forensic perspectives based on autopsy case report by Nora Fnon, Hazem Ali, Athar M Khalifa, Enas M A Mostafa, Khadiga M Abdelrahman, Mahrous A Ibrahim

“…The absence of significant medical or familial histories highlighted the diagnostic challenges posed by biventricular ACM which in this case was identified only through postmortem examination. …”
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Ultrasound-guided selective supraclavicular nerve block combined with modified clavipectoral fascial plane block for midshaft clavicule fracture surgery: a case report by Fei Jiang, Na-na Li, Yong Yang, Di Liu

“…Abstract Background Conventional anesthesia for clavicular fracture surgery poses significant challenges. General anesthesia risks pulmonary complications, while traditional nerve blocks may cause diaphragmatic paralysis or motor impairment. …”
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Two fatal cases of anti-melanoma differentiation-associated gene 5 antibody (anti-MDA5) rapidly progressive interstitial lung disease (RP-ILD): Exploring pitfalls and differences by Dina Ismail, Fatema Ezzy, Bibi Ayesha

“…Introduction: Rapidly progressive interstitial lung disease (RP-ILD) poses a critical challenge in clinical practice, characterized by nonspecific symptoms that rapidly progress to respiratory failure despite intensive management. …”
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