QTL mapping for leaf rust resistance in a recombinant inbred line population from the cross of wheat cultivars Zhongmai 578/Jimai 22 by Yue Zhang, Lei Li, Zaifeng Li, Yubing Tian, Fangping Yang, Shuanghe Cao, Xianchun Xia, Yongjing Ni, Zhonghu He, Yan Zhang, Yong Zhang, Jindong Liu

“…Abstract Leaf rust is a highly destructive disease that poses a significant threat to both the yield and quality of wheat. …”
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Genome-wide characterization and comparative phylogenomics of three Salmonella Abortusequi strains isolated from equine abortions in Kazakhstan by Temirlan Bakishev, Asylulan Amirgazin, Marat Kuibagarov, Alexander Shevtsov, Zhanar Bakisheva, Gulzhan Yessembekova, Alma Kairzhanova, Ablaikhan Kadyrov, Kui Guo, Xiaojun Wang, Sarsenbay Abdrakhmanov, Sergey Borovikov

“…Twelve Salmonella pathogenicity islands and three prophages were identified, with ST64B present in all isolates. The ac(6’)-Iaa gene, which confers resistance to aminoglycosides, was detected in all strains. …”
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Clonal overlap and resistance profiles of multidrug-resistant Klebsiella pneumoniae in humans and domestic animals in Brazil: A One Health molecular epidemiology study by Alessandra Tammy Hayakawa Ito de Sousa, Herica Makino, Marco Túlio dos Santos Costa, Stefano Luis Cândido, Kaio Lierlyson Teles Gomes, Cristiane Silva Chitarra, Marco Andrey Pepato, Francisco Kennedy Scofoni Faleiros de Azevedo, Francisco Jose Dutra Souto, Arleana Bom Parto Ferreira de Almeida, Valeria Régia Franco Sousa, Luciano Nakazato, Valéria Dutra

“…Background and Aim: The global rise of multidrug-resistant (MDR) Klebsiella pneumoniae poses a serious threat to human and animal health. …”
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Integrated multiomics analysis identifies PHLDA1+ fibroblasts as prognostic biomarkers and mediators of biological functions in pancreatic cancer by Rui Wang, Rui Wang, Guan-Hua Qin, Guan-Hua Qin, Yifei Jiang, Fu-Xiang Chen, Fu-Xiang Chen, Zi-Han Wang, Zi-Han Wang, Lin-Ling Ju, Lin Chen, Da Fu, En-Yu Liu, Su-Qing Zhang, Wei-Hua Cai

“…BackgroundPancreatic cancer (PC) is marked by extensive heterogeneity, posing significant challenges to effective treatment. …”
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In silico evaluation of N-aryl-1,10-phenanthroline-2-amines as potential inhibitors of T. cruzi GP63 zinc-metalloprotease by docking and molecular dynamics simulations by Priscila Goes Camargo, Ramon Borges da Silva, Aline Araujo Zuma, Simon J. Garden, Magaly Girão Albuquerque, Carlos Rangel Rodrigues, Camilo Henrique da Silva Lima

“…Ligand-protein consensus docking simulations using four GOLD scoring functions revealed that N-(R-phenyl) derivatives (R = CH3, OCH3, CF3, CN, NO2, F, Cl, and Br) presented poses with higher fitness scores than the N-naphthyl ones, with the six para-substituted derivatives (Phen4, p-CH3; Phen7, p-OCH3; Phen10, p-CN; Phen14, p-F; Phen17, p-Cl; and Phen18, p-Br) being more favorable than the ortho or meta ones. …”
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CRISPR/Cas13a-Assisted accurate and portable hepatitis D virus RNA detection by Yuan Tian, Zihao Fan, Xiangying Zhang, Ling Xu, Yaling Cao, Zhenzhen Pan, Yinkang Mo, Yao Gao, Sujun Zheng, Jing Huang, Huaibin Zou, Zhongping Duan, Hao Li, Feng Ren

“…Background & Aims Hepatitis delta virus (HDV) infection accelerates the progression of chronic hepatitis B virus (HBV) infection, posing a large economic and health burden to patients. …”
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Comparative evaluation of live attenuated and killed tachyzoites as vaccine candidates for toxoplasmosis by Eman E. El Shanawany, Eman H. Abdel-Rahman, Waleed A. Nemr, Soad E. Hassan, Noha M. F. Hassan, Hassan M. Desouky, Rabab Zalat, Amany Ebrahim Nofal, Raafat M. Shaapan, Salwa Sami Younis

“…Abstract Toxoplasma gondii (T.gondii) an obligate intracellular protozoan, causes toxoplasmosis, leading to significant economic losses and posing serious public health challenges worldwide. …”
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Community-level mental health screening and referral using task-sharing with student volunteers in Kerala, India: a scalable model for low and middle income countries by Saju Madavanakadu Devassy, Lorane Scaria, Shyba Babu, Rajeev S.P., Lijo K.J., Amal Tom Jose, Kiran Thampi, Robin E. Gearing

“…Abstract Background Untreated mental illness poses a significant threat to achieving global mental health targets. …”
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Influence of load-bearing wall material properties on building mine-induced dynamic response by Maciej Zajac, Krystyna Kuzniar, Tadeusz Tatara

“…Additionally, it provides a practical finding that low-stiffness materials (especially cellular concrete) can lead to increased dynamic responses in mining areas, potentially posing a risk of damage.…”
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Navigating family-witnessed resuscitation in hospitals: content analysis of free-text survey data by Annette Waldemar, Ingela Thylén

“…Helping or harming the family captured the dual perception that family presence could facilitate understanding of the resuscitation process and support grieving if the patient did not survive, while also posing a risk of trauma for family members. Conclusions: Family-witnessed resuscitation presents significant ethical and practical challenges for healthcare professionals. …”
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Benchmark dataset for hydraulic simulations of flash floods in the French Mediterranean region by J. Godet, J. Godet, P. Nicolle, N. Hocini, E. Gaume, P. Davy, F. Pons, P. Javelle, P.-A. Garambois, D. Lague, O. Payrastre

“…<p>The absence of validation or comparison data for verifying flood mapping methods poses a significant challenge in developing operational hydraulic approaches. …”
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Sustainable nanophytosome-based therapies against multidrug-resistant Escherichia coli in urinary tract infections: an in Vitro and in vivo study by Ming Ming Wen, Ibrahim A. Abdelwahab, Rania Abozahra, Sarah M. Abdelhamid, Kholoud Baraka, Heba Essam Sedky Ahmed, Wessam F. El-Hadidy

“…The rise in multidrug-resistant (MDR) E. coli strains as the predominant cause of UTIs presents a substantial public health concern and poses a challenge to existing antibiotic treatments. …”
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Perspectives of primary care nurses on the organization of the COVID-19 vaccine rollout: a qualitative study by Rhiannon Lyons, Maria Mathews, Lindsay Hedden, Julia Lukewich, Emily Gard Marshall, Jennifer E. Isenor, Jamie Wickett, Emilie Dufour, Leslie Meredith, Dana Ryan, Sarah Spencer, Crystal Vaughan, Cheryl Cusack

“…Rapidly evolving information made it difficult for nurses to stay informed and training for vaccine delivery posed barriers due to time requirements and redundancy. …”
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PO27 | B-cell lymphoproliferative disorder and acquired coagulopathy: an insidious link

“…Case Report: An 81-year-old female presented with recurrent episodes of anterior epistaxis and ecchymoses, without history of personal bleeding disorders. …”
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Genotypic characterization of extended-spectrum beta-lactamase-producing E. coli from dogs in northern Germany by Marco Werhahn Beining, Sebastian Guenther, Antina Lüebke-Becker, Stefan E. Heiden, Katharina Schaufler, Lothar Kreienbrock, Michael Schwabe

“…Many of the isolates exhibited genetic multidrug resistance and virulence features, posing challenges for effective treatment and control. …”
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Cirrhosis epidemiology in Denmark 1998–2022, and 2030 forecast by Linda Skibsted Kornerup, Frederik Kraglund, Gro Askgaard, Hendrik Vilstrup, Peter Jepsen

“…Impact and implications: Alcohol-related liver (ALD) cirrhosis poses a substantial and growing burden on hospitals worldwide. …”
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Supporting Muslim undergraduate medical students through medical school: lessons from a novel, student-led case-based learning intervention by Zain Mohammed, Zain Mohammed, Hafsah Ba, Linta Nasim, Emily Roisin Reid

“…This promoted a sense of partnership that enabled participants in the sessions to take ownership of their own learning.DiscussionCBL presented a valuable format for student-faculty discussions to promote cultural competence and equity in medical education. …”
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Psychological insights for electric vehicles by Alexis Pengfei Zhao, Shuangqi Li, Mohannad Alhazmi, Zhaoyao Bao, Xi Cheng

“…However, managing the uncertainties associated with user behavior, renewable energy generation, and dynamic grid demand poses significant challenges to achieving optimal vehicle-to-grid (V2G) system performance. …”
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Climate-related financial policies as an enabler of circularity: a new insight from selected countries of the European Union by Nguyen Hong Yen, Le Thanh Ha

“…These countries’ aggressive economic progress necessitates considerable demands for energy and raw resources, posing environmental concerns like resource exploitation and garbage creation. …”
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The Effect of Hydrogen Peroxide on Biogas and Methane Produced from Batch Mesophilic Anaerobic Digestion of Spent Coffee Grounds by Siham Sayoud, Kerroum Derbal, Antonio Panico, Ludovico Pontoni, Massimiliano Fabbricino, Francesco Pirozzi, Abderrezzaq Benalia

“…AD of SCG, while promising, is hindered by its complex lignocellulosic structure, which poses a significant challenge. This study investigates the efficacy of hydrogen peroxide (H₂O₂) pretreatment in addressing this issue, with a particular focus on enhancing biogas and methane production. …”
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