FcRn-Driven Nanoengineered Mucosal Vaccine with Multi-Epitope Fusion Induces Robust Dual Immunity and Long-Term Protection Against <i>Brucella</i> by Tingting Tian, Yuejie Zhu, Kaiyu Shang, Huidong Shi, Ruixue Xu, Mingzhe Li, Fuling Pu, Junyu Kuang, Jianbing Ding, Fengbo Zhang

“…Background: Brucellosis poses a significant public health challenge, necessitating effective vaccine development. …”
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Thoracic Anaesthesia in a Patient with Mechanical Mitral Valve: A Case Report by Shilpa Sarang Kore, Reem Barkat Khatib, Shubhangi Vijay Humane

“…Hereby, the authors present case of a 49-year-old male with longstanding RVHD, Mitral Valve Replacement (MVR), and left ventricular systolic dysfunction (ejection fraction 35%) who presented with worsening dysphagia, regurgitation, and dyspnoea. …”
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“All things equal”: ethical principles governing why autonomous vehicle experts change or retain their opinions in trolley problems—a qualitative study by Stephen R. Milford, Stephen R. Milford, B. Zara Malgir, Bernice S. Elger, Bernice S. Elger, David M. Shaw, David M. Shaw

“…Much research has been conducted on public opinion, but there are no available research findings on the ethical opinions of AV experts.ResultsFollowing reflective thematic analysis, four important findings were deduced: 1) although the expert opinions are broadly utilitarian, they are nuanced in significant ways to focus on the impacts of collision scenarios on the community as a whole. 2) Obeying the rules of the road remains a significantly strong ethical opinion. 3) Responsibility and risk play important roles in how AVs should handle collision situations. 4) Egoistic opinions were present to a limited extent.DiscussionThe findings show that the ethics of AVs still pose a serious challenge; furthermore, while utilitarianism appears to be a driving ethical principle on the surface, along with the need for both AVs and vulnerable road users to obey the rules, questions concerning community impacts and risk vs. responsibility remain strong influences among AV experts.…”
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Considerations on Safety Parameters, Product Quality and Process Reliability for the Usage of Microwaves and Plasma Torch Burners in High-Temperature Processes by Ralph Behend, Dominik Liebsch, Andreas Pestel, Hartmut Krause, Sven Eckart

“…Microwave radiation can pose health hazards, particularly if handled improperly or without adequate shielding. …”
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Assessment of root and root canal morphology in maxillary molars with fused roots using Cone Beam Computer Tomography (CBCT) in a Sri Lankan population by Ruvienath Daham Weerasinghe Rajapaksa, Manil Christopher Nishan Fonseka, Ruwan Duminda Jayasinghe, Rasika Manori Jayasinghe

“…Fused roots in maxillary molars pose important clinical implications, mainly in the field of endodontics. …”
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Forefoot Tumor of Mesenchymal Origin with Hypophosphatemic Osteomalacia: A Case Report by Myilvahanan Ganesan, Shreya P Shenoy, Kumaravel Arukutty, Senthilraja Manickavasagam

“…Such paraneoplastic tumors pose a diagnostic dilemma as they present primarily with constitutional symptoms and pathological fractures. …”
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Introducing an oncoplastic approach for centrally located breast cancer patients by Mohammadreza Karoobi, Seyed Mostafa Meshkati Yazd, Fatemeh Aminolroaya, Hadiseh Mahram, Samineh Saghafinia, Stefano Pompei, Nahid Nafissi, Pantea Khalili

“…Abstract Introduction Central breast cancers pose a unique challenge to oncoplastic surgeons, given their proximity to the nipple-areola complex and the impact on cosmetic outcomes. …”
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L'ensenyament de la història i el living history by Joan Santacana, Núria Serrat Antolí

“…Objects and documents from the past allow students to participate by posing enigmas and questions that they can solve through a true historical research. …”
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A review on drug resistance patho-mechanisms in ESKAPE bacterial pathogens by Apoorva Jain, Ajay Kumar Oli, Sughosh Kulkarni, Raghavendra D. Kulkarni, Kelmani Chandrakanth

“…These pathogens, which are distinguished by their robust antibiotic resistance mechanisms, pose a significant threat to the public health. Their ability to evade traditional antimicrobial treatments underscores the urgent need for novel therapeutic stratifies or alternative approaches to mitigate their negative impact. …”
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Multicystic Hepatocarcinoma Mimicking Liver Abscess by Evangelos Falidas, Angelos Pazidis, Georgios Anyfantakis, Konstantinos Vlachos, Christina Goudeli, Constantinos Villias

“…Multicystic HCC mimicking a liver abscess associated with septic-type fever and leukocytosis is rare, has a poor prognosis, and poses diagnostic and therapeutic dilemmas. We present the case of an 80-year-old patient, who presented with fever, leukocytosis, and large cystic masses involving right and left lobes of the liver initially considered abscesses and finally diagnosed as HCC after open drainage and liver biopsy. …”
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Metal-based nanomedicines for cancer theranostics by Hai-Jia Yu, Jian-Hua Liu, Wei Liu, Rui Niu, Bin Zhang, Yuan Xiong, Yang Liu, Ying-Hui Wang, Hong-Jie Zhang

“…Abstract The heterogeneity and invasiveness of cancer cells pose serious challenges in cancer diagnosis and treatment. …”
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Genetic assessment of apolipoprotein E polymorphism and PRNP genotypes in rapidly progressive dementias in Pakistan by Urwah Rasheed, Minahil Khalid, Aneeqa Noor, Umar Saeed, Rizwan Uppal, Saima Zafar

“…It is noteworthy that the MM homozygous genotype was present in 71 samples, VV genotype was present in 29. …”
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Application of WDXRF and EDXRF Spectrometry for Chemical Characterization in Oil Sludge using the Fundamental Parameter Algorithm by Aline Leone Muguet Pinto, Marcos Antonio Scapin, Alexandre Luiz de Souza, Cláudia Monteiro Paixão, Marycel Elena Barboza Cotrim, Sabine Neusatz Guilhen

“…Furthermore, the storage and transportation of oil sludge pose significant environmental contamination risks. …”
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Mitigating Urban Congestion: A Cooperative Reservation Framework for Automated Vehicles by David Yagüe-Cuevas, Pablo Marín-Plaza, María Paz-Sesmero Lorente, Stephen F. Smith, Araceli Sanchis, José María Armingol Moreno

“…Today’s urban environments are complex, highly congested traffic scenarios that suffer from multiple unsolved problems such as traffic jams and congestion. These problems pose a significant increase in the risks and probability of traffic accidents in modern cities, which have experienced an enormous growth in the number of vehicles. …”
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La gestion des langues au sein des Associations des Parents d’Élèves dans la ville de Ouagadougou, entre libéralisme et domination linguistique by Wendnonga Gilbert KAFANDO

“… Les Assemblées générales des Associations des Parents d’Élèves dans la ville de Ouagadougou regroupent des participants appartenant à des communautés linguistiques diverses. Il se pose alors le problème de choix de langue(s) de communication. …”
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New insights into the bacterial fitness-associated mechanisms revealed by the characterization of large plasmids of an avian pathogenic E. coli. by Melha Mellata, Jacob T Maddux, Timothy Nam, Nicholas Thomson, Heidi Hauser, Mark P Stevens, Suman Mukhopadhyay, Shameema Sarker, Aurélie Crabbé, Cheryl A Nickerson, Javier Santander, Roy Curtiss

“…Extra-intestinal pathogenic E. coli (ExPEC), including avian pathogenic E. coli (APEC), pose a considerable threat to both human and animal health, with illness causing substantial economic loss. …”
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Challenges and constraints to the sustainability of poultry farming in Thailand by Sawitree Wongtangtintharn, Sudpradthana Chakkhambang, Padsakorn Pootthachaya, Anusorn Cherdthong, Metha Wanapat

“…The rising demand for organic and ethically produced poultry products presents both market opportunities and production challenges, necessitating significant adjustments in farming practices. …”
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Spinnaker-sail sign in full-term neonates with spontaneous pneumomediastinum: a case study and scoping literature review by Ali Zamlout, Bushra Jamahiri, Elisar Jabbour

“…Case-2: a 6-hour-old boy presented with respiratory distress shortly after birth. …”
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Methods of Controlling Microbial Contamination of Food by Renata Urban-Chmiel, Jacek Osek, Kinga Wieczorek

“…Microbial contamination of food is a significant problem for the accessibility of safe food which does not pose a threat to the life and health of consumers. …”
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Application of a special nasointestinal tube in the treatment of acute pancreatitis by A. A. Kashintsev, N. Yu. Kokhanenko, V. Yu. Proutski, S. V. Anisimov, A. A. Nadeeva, Yu. N. Ulyanov, A. L. Ivanov

“…This case presentation illustrates an original method of duodenal drainage and intestinal tube feeding.A case of a patient with moderately severe acute pancreatitis and a relatively high risk of a fatal outcome is presented. …”
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