Long-term outcomes of light chain amyloidosis patients receiving heart transplant: A single-center experience by Khush Patel, MD, Zoe H. Tu, PharmD, Carrie Yuen, MD, Siddhartha Ganguly, MD, Allison N. Yun, PharmD, BCTXP, Janardhana R. Gorthi, MD, MBBS, Barry H. Trachtenberg, MD, Ashrith Guha, MD, MPH, Mahwash Kassi, MD, Ju Kim, MD, Rayan Yousefzai, MD, Kelty Baker, MD, Lawrence Rice, MD, Rammurti T. Kamble, MD, Horacio E. Adrogue, MD, Erik E. Suarez, MD, Mark Ghobrial, MD PhD, Ashish Saharia, MD, Constance M. Mobley, MD PhD, David W. Victor, MD, Jill C. Krisl, PharmD, BCPS, BCTXP, Richard Knight, MD, A. Osama Gaber, MD, Arvind Bhimaraj, MD, MPH, FACC, FHFSA

“…Light chain (AL) amyloidosis specifically poses challenges. While previous small studies have established the validity of OHT for AL amyloidosis, we present experience from a large contemporary series at a single center. …”
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Clinical and Molecular Characterization of Feline Sporotrichosis in the Brazilian Amazon: PCR-Based Identification of <i>Sporothrix brasiliensis</i> by Nayara Fátima Lazameth-Diniz, Danielle Barreto de Almeida, Flávia da Silva Fernandes, Adriana Oliveira da Silva Queiroz, Érica Simplicio de Souza, Kátia Santana Cruz, Ani Beatriz Jackisch Matsuura, Hagen Frickmann, João Vicente Braga de Souza

“…Sporotrichosis is a zoonotic fungal infection with increasing incidence in the Brazilian Amazon, primarily affecting domestic cats and posing risks to human health. This study characterized the clinical and epidemiological profiles of 29 feline sporotrichosis cases in Manaus and optimized molecular diagnostic methods for <i>Sporothrix</i> species identification. …”
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Anti-BCL2 therapy eliminates giant congenital melanocytic nevus by senolytic and immune induction by Boxuan Wei, Qingxiong Yu, Jiamin Jin, Danli Zhu, Bohan Lai, Jieyu Gu, Ran Yang, Huailiang Huang, Hongzhan Lin, Liang Zhang, Tao Zan, Feng Xie, Kang Zhang, Qingfeng Li

“…Abstract Giant congenital melanocytic nevus (GCMN) is a RAS/RAF mutation-driven syndrome characterized by extensive melanocytic lesions, posing psychological challenges and a lifelong risk of malignancy. …”
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A machine learning approach to predict phyllosphere resistome abundance across urbanization gradients by Rui-Ao Ma, Yi-Hui Ding, Shifa Zhong, Ting-Ting Jing, Xuechu Chen, Si-Yu Zhang

“…The heightened transmission potential in urban greenspaces may facilitate the spread of antibiotic resistance spread to human pathogens, which poses significant public health threats.…”
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An Oxidation Gradient Straddling the Small Planet Radius Valley by Collin Cherubim, Robin Wordsworth, Dan J. Bower, Paolo A. Sossi, Danica Adams, Renyu Hu

“…We present a population-level view of volatile gas species (H _2 , He, H _2 O, O _2 , CO, CO _2 , CH _4 ) distribution during the sub-Neptune to rocky planet transition, revealing in detail the dynamic nature of small planet atmospheric compositions. …”
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Exploring dihydropyrimidone derivatives as modulators of carbohydrate catabolic enzyme to mitigate diabetes by Syed Parween Ali, Farheen Mansoor, Shaymaa Fadhel Abbas Albaayit, Farman Ali, Ayed A. Dera, Muhammad Shahbaz, Jawad Ullah, Hailah M. Almohaimeed, Reem M. Gahtani, Ahmed M. Abdulfattah, Fahad M. Alshabrmi, Sarfaraz Alam, Saeed Ullah

“…Abstract Diabetes is a prevalent and serious metabolic disorder affecting millions globally, and it poses extensive health risks due to elevated blood glucose levels. …”
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Seasonal drought classification and its characteristics in the red soil region of southern China by Yong Zhong, Lei Gao, Xinhua Peng, Asim Biswas, Wei Hu, Yaji Wang

“…Study region: The red soil region of southern China Study focus: The red soil region of southern China faces serious seasonal drought, which poses a great threat to the sustainable development of local agriculture. …”
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Detection of Four Intermediate-mass Stars with Cool Companions in Low Mass Ratio Eclipsing Binaries by Linfeng Chang, Shengbang Qian, Lei Zang, Fuxing Li

“…\limits^{{\rm{d}}}$ 8) does not, which poses a challenge to the Kraft break. By plotting these components in the H-R diagram, it hints that all systems are main-sequence (MS) primaries with pre-MS companions. …”
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Microneedles-based local photothermal therapy promotes browning of white adipose tissue and combats obesity by Le Li, Hanxing Chen, Kexin Zhang, Xinying Hu, Mengfan Xu, Taotao Wen, Jialuo Ding, Mengyuan Zhao, Yeying Li, Yu Su, Zhenkun Lin

“…Obesity has emerged as a global epidemic, posing a significant threat to human health and imposing a huge burden on healthcare systems worldwide. …”
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Research on the Data-Driven Identification of Control Parameters for Voltage Ride-Through in Energy Storage Systems by Liming Bo, Jiangtao Wang, Xu Zhang, Yimeng Su, Xueting Cheng, Zhixuan Zhang, Shenbing Ma, Jiyu Wang, Xiaoyu Fang

“…By relying on measured data for parameter inversion, the method circumvents the limitations posed by commercial confidentiality, providing a novel technical pathway to enhance the fault ride-through (FRT) performance of energy storage systems (ESSs). …”
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Optimizing the lead time of operational flexibility trading from distributed industrial energy systems in future energy and flexibility markets by Daniel Bull, Adrian Bürger, Markus Bohlayer, Marco Braun, Anke Weidlich

“…To address the challenges posed by increasing shares of variable renewable power generation in the electric grid, flexibility procurement platforms are being actively developed. …”
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Unravelling climate misinformation: fact-checking of climate disinformation in spanish-speaking podcasts by Mercè Cisneros, Jon X Olano Pozo, Anna Boqué-Ciurana, Caterina Cimolai, Daniel Dermit, Andrea Arnal, Marc Masip, Javier Sigro, Enric Aguilar

“…Climate misinformation poses a major obstacle, with radio podcasts—an influential medium—contributing to its spread. …”
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Injuries in German national short-track speed skating athletes by Jan Ziegler, Heidrun Beck, Roland L. Bell, Dominik Matzner, Xinggui Tian, Stefan Zwingenberger

“…Objectives: Short-Track Speed Skating (STSS) is a high-intensity ice sport characterized by fast-paced races and proximity among athletes, which inherently poses a risk for falls and injuries. This paper presents a comprehensive analysis of orthopedic-traumatological injuries in German national STSS athletes with comparisons to previous studies. …”
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Role of extracellular vesicles in immune modulation, angiogenesis, progression and therapeutic resistance of glioblastoma by Muhammad Izhar, Ahed H. Kattaa, Amirhossein Akhavan-Sigari, Elaheh Shaghaghian, Yusuke S. Hori, Fred C. Lam, Deyaaldeen AbuReesh, Sara C. Emrich, Louisa Ustrzynski, Armine Tayag, Steven D. Chang, David J. Park

“…Targeting EV-mediated communication presents a promising therapeutic strategy for addressing the challenges posed by this deadly brain tumor.…”
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Health risk assessment of heavy metals based on source analysis and Monte Carlo in the Lijiang River Basin, China by Wanjun Zhang, Cunlin Xin, Wenyue Du, Shi Yu

“…Monte Carlo risk assessments indicate that Al poses non-carcinogenic risks to both adults and children, whereas Cd presents non-carcinogenic risks specifically to children and significant carcinogenic risks to all populations. …”
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Perfusion process with tangential flow filtration for oncolytic VSV-GP production by Orsolya Hamusics, Anja Wittmann, Katrin Hasler, Sabrina Müller, Daniel Birk, Ingo H. Gorr, Alexander Brix, Jorge Soza-Ried

“…To ensure clinical efficacy, doses with high titers are required, which poses a challenge for the manufacturing process. …”
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Dysregulated Adaptive Immune Responses to SARS-CoV-2 in Immunocompromised Individuals by Núria Mayola Danés, Demi Brownlie, Rebecca Folkman, Anna Nordlander, Kim Blom, Renata Varnaite, Julia Niessl, Oskar Karlsson Lindsjö, Sandra Söderholm, Mira Akber, Puran Chen, Marcus Buggert, Andreas Bråve, Jonas Klingström, Piotr Nowak, Nicole Marquardt, Klara Sondén, Ola Blennow, Sara Gredmark-Russ

“…The SARS-CoV-2 virus poses a significant risk to immunocompromised patients, who display weakened immunity and reduced seroconversion following infection and vaccination. …”
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Molecular Genotyping by 20K Gene Arrays (Genobait) to Unravel the Genetic Structure and Genetic Diversity of the <i>Puccinia striiformis</i> f. sp. <i>tritici</i> Population in the... by Mudi Sun, Wenbin Chen, Qianrong Yong, Xinyu Kong, Xue Qiu, Jie Zhao

“…<i>tritici</i> (<i>Pst</i>), poses a significant threat to wheat production in China. …”
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Aptamer-Conjugated Magnetic Nanoparticles Integrated with SERS for Multiplex Salmonella Detection by Fan Sun, Kun Pang, Keke Yang, Li Zheng, Mengmeng Wang, Yufeng Wang, Qiang Chen, Zihong Ye, Pei Liang, Xiaoping Yu

“…<i>Salmonella</i> is a rapidly spreading and widespread zoonotic infectious disease that poses a serious threat to the safety of both poultry and human lives. …”
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Global equine parasite control guidelines: Consensus or confusion? by Martin K. Nielsen, Alison Pyatt, Jodie Perrett, Eva Tydén, Deborah van Doorn, Tina H. Pihl, Jennifer S. Schmidt, Georg von Samson-Himmelstjerna, Anne Beasley, Ghazanfar Abbas, Abdul Jabbar

“…Equine parasite control has historically been characterized by confusing and conflicting information, posing significant challenges for veterinarians and horse owners to make evidence-based decisions. …”
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