Assessing Implantation Sites for Pancreatic Islet Cell Transplantation: Implications for Type 1 Diabetes Mellitus Treatment by Vinícius Gabriel Silvério Scholl, Leonardo Todeschini Justus, Otávio Simões Girotto, Kelly Karine Pasqual, Matheus Henrique Herminio Garcia, Fernando Gonçalves da Silva Petronio, Aline Flores de Moraes, Sandra Maria Barbalho, Adriano Cressoni Araújo, Lucas Fornari Laurindo, Cristina Pires Camargo, Maria Angélica Miglino

“…The subcutaneous space is notable for its accessibility and lower invasiveness, although its poor vascularization poses significant challenges. These challenges can be mitigated with bioengineering strategies. …”
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Downshifting Encapsulant: Optical Simulation Evaluation of the Solution to Ultraviolet‐Induced Degradation in Silicon Heterojunction Solar Cells by Binbin Xu, Karsten Bittkau, Alexander Eberst, Kai Zhang, Yanxin Liu, Jinli Yang, Weiyuan Duan, Muhammad Ainul Yaqin, Vladimir Smirnov, Chunlan Zhou, Wenjing Wang, Xiaohua Xu, Andreas Lambertz, Uwe Rau, Kaining Ding

“…Ultraviolet (UV)‐induced degradation (UVID) poses a significant challenge for the prospective mass production of silicon heterojunction (SHJ) solar cells, known for their high efficiency. …”
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Optimizing energy transfer in NIR ruthenium(II) complexes to enhance stability and efficiency in sonodynamic therapy by Dazhuang Xu, Qixuan Dai, Jian Sun, Yibo An, Ziying Wang, Lijuan Yang, Zhixiang Lu, Chengchao Chu, Gang Liu

“…Sonodynamic therapy (SDT) holds a distinct advantage over traditional photodynamic therapy (PDT) by harnessing ultrasound-triggered sonosensitizer activation, enabling deeper tissue penetration for treating deep-seated tumors. In this study, we present IR780-TPEY-Ru, a nanoplatform specifically engineered for imaging-guided SDT to address challenges posed by deep-seated tumors. …”
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Evaluation of the Bioactivity of Phenolic Compounds from the <i>Sargassum pallidum</i> and Development of Their Stable Emulsion and Cream by Shuoqi Wang, Li Wang, Yiqing Sun, Jia Yang, Wei Liu, Tingting Wu, Rui Jia

“…Chronic inflammation poses a significant threat to physical health. The increasing prevalence of skin disorders is attributed to external factors such as environmental pollution and UV-induced stress. …”
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Combined Localization Method for Multimodal Wheel-Track Robots in Sheltered Space by Jiazhen Lin, Zhong Su, Hui Zhao, Yuxin Zhao, Xinkai Wang, Hao Zhou

“…In response to the localization challenges posed by multi-modal motion mode transitions during the locomotion of tracked-wheel robots in sheltered spaces, this paper presents a combination localization method based on Inertial Navigation System/Odometry (INS/OD). …”
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Successful use of a fully closed-loop insulin delivery system in an adolescent with diabetes secondary to pancreatitis – a case report by Abirami Namasivayam, Sandra Walton-Betancourth, Helen Hysted, Vipan Datta, Cliodhna Myles, Charlotte Boughton, M. Loredana Marcovecchio, Ajay Thankamony

“…However, variable tolerance to nasogastric feeds and frequent titration of TPN posed significant challenges to insulin therapy. …”
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Unravelling the advances of CRISPR-Cas9 as a precise antimicrobial therapy: A systematic review by Hannay Crystynah Almeida de Souza, Pedro Panzenhagen, Anamaria Mota Pereira dos Santos, Ana Beatriz Portes, Juliana Fidelis, Carlos Adam Conte-Junior

“…Conclusions: Despite challenges in delivery strategies and clinical application, studies integrating nanotechnology present promising approaches to overcome these limitations. …”
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Exploring the potential of ultrasound: Novel approaches to collagen extraction, modifications, and polypeptide preparation by Yongjun Zhao, Mingming Zhong, Shuixiu Pang, Ping Liu, Yufan Sun, Qiufang Liang, Kai Yu, Junxia Wang, Abdur Rehman, Arif Rashid, Haile Ma, Xiaofeng Ren

“…Nevertheless, the suboptimal extraction rate and inefficiencies associated with conventional collagen processing posed significant barriers to its widespread application. …”
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A Novel BODIPY-Zn Complex as Innovative Sonosensitizer for Enhanced Sonodynamic Therapy by Jungmin Lee, Soeun Lee, Gihoon Jo, Eunbin Hwang, Junhyoung Lee, Jiyou Han, Hyo Sung Jung

“…Ultrasound (US)-based sonodynamic therapy (SDT) presents a promising and secure approach to treating cancer with the advantage of enhanced tissue penetration, making it a favorable option compared with traditional photodynamic therapy. …”
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Successful treatment of generalized pustular psoriasis during pregnancy with secukinumab in a patient hypersensitive to spesolimab: a case report by Shuang Zhang, Guoyao Peng, Yun Zhang, Liping Luo, You Li, Jiaxin Luo, Tao Yu, Hongwei Zhang, Xinyi Nie, Xia Li, Jie Xiang, Chengcheng Liao

“…In addition to skin manifestations, this condition may be accompanied by fever, muscle pain, joint pain, systemic inflammation, or organ failure. GPP during pregnancy poses a serious threat to both mother and fetus, with limited options for medication. …”
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Tuberculosis and COVID-19 interaction: A review of biological, clinical and public health effects by D. Visca, C.W.M. Ong, S. Tiberi, R. Centis, L. D’Ambrosio, B. Chen, J. Mueller, P. Mueller, R. Duarte, M. Dalcolmo, G. Sotgiu, G.B. Migliori, D. Goletti

“…Evidence is accumulating on the interaction between tuberculosis (TB) and COVID-19.The aim of the present review is to report the available evidence on the interaction between these two infections. …”
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Progressive Guided Fusion Network With Multi-Modal and Multi-Scale Attention for RGB-D Salient Object Detection by Jiajia Wu, Guangliang Han, Haining Wang, Hang Yang, Qingqing Li, Dongxu Liu, Fangjian Ye, Peixun Liu

“…Nevertheless, the acquired depth map is often with uneven quality, due to the interference of depth sensors and external environments, posing a challenge when trying to minimize the disturbances from low-quality depth maps during the fusion process. …”
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UV-Vis spectroscopy coupled with firefly algorithm-enhanced artificial neural networks for the determination of propranolol, rosuvastatin, and valsartan in ternary mixtures by Ahmed Serag, Maram H. Abduljabbar, Yusuf S. Althobaiti, Farooq M. Almutairi, Shaker T. Alsharif, Rami M. Alzhrani, Marwa F. Ahmed, Atiah H. Almalki

“…Abstract In the present study, a simple, rapid and cost-effective analytical method was developed for the simultaneous determination of three commonly prescribed cardiovascular drugs: propranolol, rosuvastatin and valsartan. …”
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Inhibitory Effects of Nisin and Gallium (III) Nitrate Hydrate on Planktonic and Adhered Cells and Implications for the Viable but Non-Culturable State by Valeria Poscente, Luciana Di Gregorio, Roberta Bernini, Annamaria Bevivino

“…A viable but non-culturable (VBNC) state, a survival strategy of non-spore-forming bacteria in response to adverse conditions, poses a significant challenge for public health and food safety. …”
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Backdoor Attack to Giant Model in Fragment-Sharing Federated Learning by Senmao Qi, Hao Ma, Yifei Zou, Yuan Yuan, Zhenzhen Xie, Peng Li, Xiuzhen Cheng

“…Compared with the previous works where the models are fully exchanged, the fragment-sharing pattern poses some new challenges for the backdoor attacks. …”
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Molecular Epidemiology of Beak and Feather Disease Virus (BFDV), Avian Polyomavirus (APV-1), Psittacid Herpesvirus 1 (PsHV-1), and Avian Metapneumovirus (aMPV) in Birds Kept as Non... by Riccardo Baston, Claudia Maria Tucciarone, Alberto Caudullo, Francesca Poletto, Matteo Legnardi, Mattia Cecchinato, Michele Drigo, Giovanni Franzo, Diego Cattarossi

“…These animals can harbor various pathogens and act as reservoirs, posing risks to native wildlife through legal or illegal trade, escapes, or intentional releases. …”
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Dynamic Cap‐Mediated Substrate Access and Potent Inhibitor Design of Monkeypox Virus I7L Protease by Haixia Su, Guoqing Wu, Muya Xiong, Yuhang Wang, Junyuan Cao, Mengyuan You, Yingchun Xiang, Tianqing Nie, Minjun Li, Gengfu Xiao, Leike Zhang, Qiang Shao, Yechun Xu

“…Abstract Monkeypox virus (MPXV), an orthopoxvirus that has long been endemic in Africa, has posed a significant global health threat since 2022. …”
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Solar-driven defluorination via hydroxyl radical spillover for complete mineralization of organofluorine pollutants without fluoride byproducts by Lei Zheng, Jing-Lan Zhang, Zhixin Zheng, Chujie Huang, Yi-Lin Xie, Xu-Bing Li, Wondu Dagnaw Fentahun, Tieyu Wang, Qing-Xiao Tong, Jing-Xin Jian

“…Abstract The recalcitrance of fluorinated organic pollutants—featuring robust Csp²-F and Csp³-F bonds—poses critical challenges to aquatic ecosystems due to their extreme persistence and bioaccumulation. …”
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Transcription regulation of African swine fever virus: dual role of M1249L by Dongming Zhao, Nan Wang, Xiaoying Feng, Zhenjiang Zhang, Kongen Xu, Tao Zheng, Yunge Yang, Xuemei Li, Xianjin Ou, Rui Zhao, Zihe Rao, Zhigao Bu, Yutao Chen, Xiangxi Wang

“…Abstract African swine fever virus (ASFV), which poses significant risks to the global economy, encodes a unique host-independent transcription system. …”
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Aging and urban innovation: a human capital perspective by Jinghang Cui, Jinghang Cui, Rong Zhou, K. Jason Crandall, K. Jason Crandall, Mingxuan Cui, Ruirui Bai, Ruirui Bai, Yi Jia

“…It is imperative for policymakers to implement recommendations that address population aging and encourage innovation in order to navigate the challenges posed by an aging population and promote a vibrant and dynamic economy.…”
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