Molecular basis of ligand binding and receptor activation at the human A3 adenosine receptor by Liudi Zhang, Jesse I. Mobbs, Felix M. Bennetts, Hariprasad Venugopal, Anh T. N. Nguyen, Arthur Christopoulos, Daan van der Es, Laura H. Heitman, Lauren T. May, Alisa Glukhova, David M. Thal

“…Our comprehensive structural and functional characterisation of A3AR advances our understanding of adenosine receptor pharmacology and establishes a foundation for developing more selective therapeutics for various disorders, including inflammatory diseases, cancer, and glaucoma.…”
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The role of grid geometry and relative orientation in the performance of a retarding potential analyzer by Thomas Trottenberg, Florian Bansemer, Marcel Hesse, Holger Kersten, Jens Laube, Viktor Schneider, Björn Schuster, Lars Seimetz, Robert F. Wimmer-Schweingruber

“…Several models are presented to reproduce and understand these observations. …”
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Metabolic acclimation to warming links unexpected immune activation and sexual dimorphism attenuation in Xenopus tropicalis by Jiaying Li, Jiahao Zhu, Ayi Budian, Yiwei Zeng, Shouhong Wang, Yuzhou Gong, Xungang Wang, Longhui Zhao, Na Tang, Si Zheng, Rong Han, Songping Zhan, Ting Xie, Ting Chen, Xiangzhen Li, Jianping Jiang

“…These results not only indicate a far more complex adaptive response to future climate change than previously anticipated, but also provide a concise method for constructing animal models to explore diseases related to homeostatic disorders.…”
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Quantum Surface Topological Code for Bell State Stabilization in Superconducting Physical Qubit Systems by Jordi Fabián González-Contreras, Erik Zamora, Jesús Yaljá Montiel-Pérez, Juan Humberto Sossa-Azuela, Elsa Rubio-Espino, Víctor Hugo Ponce-Ponce

“…In this study, an experimental advancement in Bell state stabilization is presented, which utilizes surface codes for quantum error correction across three quantum computers: ibm_fez, ibm_torino, and ibm_brisbane. …”
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The evolution of virtual identity: a systematic review of avatar customization technologies and their behavioral effects in VR environments by Hamid Ouhnni, Acim Btissam, Belhiah Meryam, Karim El Bouchti, Zaoui Seghroucheni Yassine, Souad Najoua Lagmiri, Benachir Rigalma, Soumia Ziti

“…The concluding section articulates prospective trajectories for innovation within this domain, underscoring opportunities for further inquiry and the formulation of more diverse and adaptable strategies for avatar customization, thereby accommodating users across a spectrum of virtual environments.…”
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Contested logistics: Resilience of strategic highways and railways by Sukhwan Chung, Daniel Sardak, Maksim Kitsak, Andrew Jin, Igor Linkov

“…Our findings reveal that highways are more resilient than railways, with greater capacity to absorb targeted disruptions.. …”
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Lateral Percolation and Its Effect on Shale Gas Accumulation on the Basis of Complex Tectonic Background by Kun Zhang, Zhenxue Jiang, Xuelian Xie, Zhiye Gao, Tianlin Liu, Lishi Yin, Chengzao Jia, Yan Song, Chang’an Shan, Yinghui Wu, Pengfei Wang

“…Gas in the shale layer percolates much more in the direction parallel to the plane. Therefore, the accumulation pattern of shale gas indicates a complex tectonic background. …”
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Bringing students closer to the issues of indoor environmental quality and technology using nEMoS device: an experience in Albania by Salamone Francesco, Lorenzo Belussi, Ludovico Danza, Etleva Dobjani, Matteo Ghellere, Italo Meroni, Arben Shtylla, Saimir Shtylla

“…The article presents the outcomes of a monitoring campaign and a survey performed in a~school building in Tirana. …”
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Substantial continental temperature rise over the Paleocene-Eocene Thermal Maximum in the Pyrenees by Gábor Újvári, Sándor Kele, László Rinyu, Aitor Payros, Kim H. Stadelmaier, János Kovács, Ivett Kovács, Bernadett Bajnóczi, Victoriano Pujalte, Birger Schmitz, Stefano M. Bernasconi

“…Continental proxy and model data indicate reduced (0.7–0.4 °C/degree) meridional temperature gradients between 25 and 75°N latitudes, indicating more uniform heat distribution across latitudes than at present.…”
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Role of Intramedullary Fibular Fixation: Strategies for Addressing Complex Pilon Fractures by Kyle Auger, Ian S Hong, Jaclyn M Jankowski, Richard S Yoon

“…Aim and background: Pilon fractures are usually the result of a high-energy mechanism and are widely considered more of a soft tissue injury secondary to the high rates of soft tissue complications that arise from them. …”
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The EU global health strategy: from policy to implementation by Jolene Skordis, Guenter Froeschl, Sante Leandro Baldi, Astrid Berner-Rodoreda, Nuria Casamitjana, Frank Cobelens, Kerstin Klipstein-Grobusch, Mario Raviglione, Alberto Rocamora, Anne-Mieke Vandamme, Antoni Plasència

“…The trategy currently lacks a fully-resourced and clearly hypothecated funding mechanism and there is little evidence to date of the stated commitment that Global Health will be considered in all EU policy areas. In the present geopolitical climate, a speedy acceptance of both the policy and an implementation plan is needed more than ever.…”
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Wheat improves the quality of coarse cereals steamed bread by changing the gluten network by Mengru Han, Jiayue Zhou, Jiale Wang, Aliaksandr Ivanistau, Qinghua Yang, Baili Feng

“…Compared with the coarse cereal doughs, the reconstituted doughs presented a significantly lower free sulfhydryl content but more intermolecular disulfide bonds, which enhanced gluten network formation. …”
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Evolutionary age correlates with range size across plants and animals by Adriana Alzate, Roberto Rozzi, Julian A. Velasco, D. Ross Robertson, Alexander Zizka, Joseph A. Tobias, Adrian Hill, Christine D. Bacon, Thijs Janzen, Loïc Pellissier, Fons van der Plas, James Rosindell, Renske E. Onstein

“…Abstract More than 40 thousand species of plants and animals are facing extinction worldwide. …”
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A companion to the preclinical common data elements for rodent genetic epilepsy models. A report of the TASK3‐WG1B: Paediatric and genetic models working group of the ILAE/AES join... by Massimo Mantegazza, Stėphane Auvin, Melissa Barker‐Haliski, Anna‐Maria Katsarou, Hana Kubova, Aristea S. Galanopoulou, Bridgette Semple, Christopher A. Reid

“…These CRFs provide tools that allow investigators to more uniformly describe core experimental data on different genetic models across laboratories, with the aim of improving experimental reproducibility and thus translational impact of such studies.…”
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Generation of Orbital Angular Momentum Beam With Circular Polarization Ceramic Antenna Array by Ke Bi, Jianchun Xu, Daquan Yang, Yanan Hao, Xinlu Gao, Shanguo Huang

“…Even considering the enormous loss in cables and power divider, the receiving antenna still can receive the electromagnetic characteristic of the OAM beams at a place more than 2 m away from the antenna array. Experimental results presented in this paper demonstrate the excellent performance of the OAM beams when generated with the proposed ceramic antenna array configuration.…”
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Controlled Inflammation Drives Neutrophil‐Mediated Precision Drug Delivery in Heterogeneous Tumors by Yunfei Guo, Yiming Li, Jianmin Li, Haoran Cai, Kangkang Liu, Dengyi Duan, Wenyi Zhang, Gang Han, Yang Zhao

“…The findings pave the way for more effective and broadly applicable cancer treatments, potentially addressing the long‐standing challenge of tumor heterogeneity.…”
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Ileocecal and appendiceal intussusception associated with typhlitis in a child with medullary aplasia: A case report by Fatima Zohra El Yaagoubi, MD, Youssef Berday, MD, Fatima Ellachgar, MD, Mounir El Bied, MD, Adam Hajine, MD, Soukaina Wakrim, MD

“…Its association with ileocolic intussusception, particularly in the context of mural thickening caused by typhlitis, is even more uncommon. We present a 9-year-old boy with medullary aplasia who developed diffuse abdominal pain, vomiting, and dark stools. …”
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Enhancing the Biological Functionality of Hydrogels Using Self-Assembling Peptides by Woo Hyun Kwon, Kyoung Choi, Sang Jun Park, GeumByeol Park, Cho Young Park, Yoo Han Seo, Chun-Ho Kim, Jun Shik Choi

“…Hydrogels are ECM-mimicking three-dimensional (3D) networks that are widely used in biomedical applications; however, conventional natural and synthetic polymer-based hydrogels present limitations such as poor mechanical strength, limited bioactivity, and low reproducibility. …”
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Kawasaki disease in children: diagnosis, treatment, and therapeutic guidelines in light of a clinical case by Mateusz Heba, Aleksandra Kocjan, Elżbieta Rychlicka, Jakub Kozłowski, Alicja Kamińska, Bartłomiej Żaczek, Marta Czubaj-Kowal

“…The primary symptoms include a high fever persisting for more than 5 days, lymphadenopathy, and skin changes. …”
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Ranges of B, Cd, Cr, Cu, Fe, Pb, Sr, Tl, and Zn Concentrations and Isotope Ratios in Environmental Matrices from an Urban Area by Nicola Pallavicini, Emma Engström, Douglas C. Baxter, Björn Öhlander, Johan Ingri, Scott Hawley, Catherine Hirst, Katerina Rodushkina, Ilia Rodushkin

“…Sequential extractions were also performed on soil samples from 6 depth profiles providing more detailed information on the variability of elemental concentrations and isotope ratios between the elemental pools present in soil. …”
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