High-throughput LDI MS technology decodes the distinct metabolic landscape of prostate cancer in a large-scale cohort by Xinrong Jiang, Chen Zhang, Jing Le, Jie Zhang, Shuo Cao, Xinran Xu, Xiaoming Chen, Sheng Cheng, Haitao Yu, Haofei Jiang, Ruichen Zang, Kunyu Wang, Weiwu Chen, Haobo Fan, Jianmin Wu, Yanlan Yu, Guoqing Ding

“…Abstract Background Prostate cancer (PCa) remains a leading global malignancy, yet current diagnostic reliance on prostate-specific antigen (PSA) testing is limited by suboptimal sensitivity and specificity for early-stage detection. The present study aims to establish an effective high-throughput screening technique for accurate PCa diagnosis. …”
Get full text

Molecular identification of zoonotic taeniids metacestodes in several rodent species trapped in Central Europe by Tomáš Husák, Zuzana Čadková, Ondřej Máca, Ondřej Máca, Marek Kouba, Zdeňka Klimková, Richard Sehnal, Jana Nápravníková, Václava Hrabětová, Ivana Jankovská, Jaroslav Vadlejch, Iva Langrová

“…Further, we also identified co-infection by more metacestode species or haplotypes. No rodent liver samples tested were positive for Echinococcus multilocularis or Hydatigera taeniaeformis sensu stricto, either through morphological or molecular identification methods. …”
Get full text

Behaviour change interventions to promote physical activity in people with intermittent claudication: the OPTIMA systematic review by Ukachukwu O Abaraogu, Philippa Dall, Chris Seenan, Sarah Rhodes, Trish Gorely, Joanna McParland, Julie Brittenden, Ebuka M Anieto, Lorna Booth, Cathy Gormal, Jeremy Dearling, Candida Fenton, Sarah Audsley, Kimberley Fairer, Lindsay Bearne, Dawn A Skelton

“…Although some costs were presented, no studies considered the cost of implementation. …”
Get full text

Hypocalcemia associated with adverse outcomes following severe traumatic injury in the Western Cape of South Africa: a secondary analysis of multicenter data from the Epidemiology... by Christiaan A. Rees, Jessica L. Wild, Mengli Xiao, Lani L. Finck, Jessica B. Oudakker, Hendrick J. Lategan, George Oosthuizen, Shaheem de Vries, Janette Verster, Mohammed Mayet, Lesley Hodsdon, Karlien Doubell, Leigh Wagner, L’Oreal Snyders, Denise Lourens, Elmin Steyn, Julia M. Dixon, Steven G. Schauer, Nee-Kofi Mould-Millman

“…Here, we describe adverse outcomes associated with severe hypocalcemia among a cohort of individuals presenting to emergency care following acute traumatic injury in a resource-limited setting. …”
Get full text

A survey of hormone replacement therapy use among resistance-trained women across states of menopause transition – a preliminary analysis by John Holtje, Anna Oelmann, Valeria V. Silva Ramirez, Gretchen Shelton, Landon Shannahan, Nam Nguyen, Jacey Greece, Laura Pyott, Stacy Ann Cunnington, Laurin Conlin, Vonda J. Wright, Bill I. Campbell

“…In the survey, HRT use was defined as taking estrogen or progesterone. Data is presented descriptively.Results A total of 943 subjects identified themselves as post-menopausal. …”
Get full text

Regional and whole-brain neurofunctional alterations during pain empathic processing of physical but not affective pain in migraine patients by Dan Liu, Menghan Li, Heng Jiang, Yiqi Mi, Xiaolei Xu, Yali Zhou, Yaxian Hou, Yuquan Shen, Michael Maes, Xiao Xiao, Feng Zhou, Luca Giani, Keith M. Kendrick, Benjamin Becker, Stefania Ferraro

“…Abstract Background Accumulating evidence suggests that migraine patients present abnormal brain responses to salient sensory and emotional stimuli. …”
Get full text

Presence and Evolution of Radiological Changes at 6 and 12 Months After COVID-19 Pneumonia and Their Risk Factors by Celia Roig-Martí, Antonio Navarro-Ballester, María-Pilar Fernández-García, Ignacio Pérez-Catalán, Ana Segura-Fábrega, María Varea-Villanueva, Sofía Folgado-Escudero, Germán Herrero-Rodríguez, Elena Domínguez-Bajo, Sergio Fabra-Juana, María-José Esteve-Gimeno, María-Lidón Mateu-Campos, Jorge Usó-Blasco, José-Manuel Ramos-Rincón

“…<i>Conclusions</i>: Parenchymal patterns seem to be more frequent than reticular and fibrotic patterns after COVID-19 pneumonia. …”
Get full text

Comparative analysis of data-driven models on detection and classification of electrical faults in transmission systems: Explainability, applicability and industrial implications by Chibueze D. Ukwuoma, Dongsheng Cai, Chiagoziem C. Ukwuoma, Chinedu I. Otuka, Qi Huang

“…These findings highlight the model's potential to improve fault detection accuracy and reliability, contributing to more efficient and secure energy transmission infrastructures.…”
Get full text

Arrhythmia burden, symptoms and quality of life in female and male endurance athletes with paroxysmal atrial fibrillation: a multicentre cohort study in Norway, Australia and Belgi... by Adrian Elliott, Andre La Gerche, Bente Morseth, Maja-Lisa Løchen, Arnljot Tveit, Marius Myrstad, Jon Magne Letnes, Guido Claessen, Rik Willems, Bjarne Martens Nes, Turid Apelland, Amy Mitchell, Kristel Janssens, Hielko Miljoen, Kristoffer Robin Johansen, Eivind Sørensen, Jan Pål Loennechen, Kristine Folkenborg, Kristin Espolin Johnson, Vegard Malmo, Andreas Berg Sellevold, Rune Byrkjeland, Steve Enger, Sophia Onarheim, Ingrid Haagenrud Langmo, Fedelix Pethogo Brown, Lena Marie Kristiansen, Sevda Ece Kizilkilic, Vigdis Bache Semb

“…There were large individual variations between the athletes concerning AF burden, symptoms and QoL.Conclusions Although most athletes were still competing, more than half had troublesome symptoms. One-third had reduced QoL, which was associated with higher AF burden and longer duration of AF episodes. …”
Get full text

Comparison of Valve Academic Research Consortium (VARC)‐2 and VARC‐3 Criteria for Bleeding Complications After Transcatheter Aortic Valve Replacement by Stephan Nienaber, Janosch Himken, Max Meertens, Victor Mauri, Samuel Lee, Jonathan Curio, Elmar Kuhn, Richard Nies, Kaveh Eghbalzadeh, Johannes Dohr, Stephan Baldus, Hendrik Wienemann, Matti Adam

“…Results VARC‐3 bleeding was 2.5 times more prevalent than VARC‐2 (13.9% versus 34.4%), as VARC‐3 includes nonattributable blood loss >3 g/dL as a bleeding event. …”
Get full text

Direct-fed microbials optimize ruminal fermentation, microbial ecosystem and milk quality to enhance the lactation performance of Sanhe dairy cows by Aoyu Jiang, Zixin Liu, Ziyan Yang, Shizhe Zhang, Jian Wu, Chuanshe Zhou, Zhiliang Tan

“…In predictive analysis of microbial functional genes, the treatment group was enriched with more genes encoding hemicellulose-degrading enzymes such as GH10, GH30, and GH67, while the relative abundance of genes encoding enzymes that metabolize ammonia was increased. …”
Get full text

A decomposition of Fisher’s information to inform sample size for developing or updating fair and precise clinical prediction models for individual risk—part 1: binary outcomes by Richard D. Riley, Gary S. Collins, Rebecca Whittle, Lucinda Archer, Kym I. E. Snell, Paula Dhiman, Laura Kirton, Amardeep Legha, Xiaoxuan Liu, Alastair K. Denniston, Frank E. Harrell, Laure Wynants, Glen P. Martin, Joie Ensor

“…For models estimating the risk of a binary outcome, previous research has outlined sample size calculations that target low overfitting and a precise overall risk estimate. However, more guidance is needed for targeting precise and fair individual-level risk estimates. …”
Get full text

Genetic Divergence and Isolation of the Green Sea Turtle (Chelonia mydas) in the Red Sea by K. Scott, S. He, R. S. Hardenstine, L. K. Tanabe, H. Barrios‐Garrido, M. P. Jensen, L. Afiq‐Rosli, N. E. Wildermann, C. M. Duarte, J. E. M. Cochran, M. L. Berumen

“…Haplogroup one comprised 85% of our sample library and four haplotypes (CmP71.1–CmP71.4), three of which were previously unreported, while haplogroup two was much less prevalent (15% of the sample library) and consisted of a single novel haplotype (CmP62.2) more closely related to Arabian Gulf haplotypes. …”
Get full text

Mutations in the “hot spots” of the <i>FLT3</i>, <i>NPM1</i>, <i>IDH1</i>, <i>IDH2</i> and <i>DNMT3A</i> genes in acute myeloid leukemia by E. N. Voropaeva, M. V. Burundukova, A. A. Lyzlova, I. A. Chukhontseva, V. N. Maksimov, T. I. Pospelova

“…The purpose of the study was to systematize and present up-to-date data on the prevalence, combination and clinical significance of mutations in the “hot spots” of the FLT3, NPM1, IDH1, IDH2, DNMT3A genes in acute myeloid leukemia (AML). …”
Get full text

Algoritmo para generar formulas de características geométricas de las secciones planas, su implementación en DERIVE // Algorithm for the calculation of the geometric characteristic... by Rolando Rivero-Galán

“…</p><p>The present work has as objective the making of a program for computer, using the mathematical</p><p>assistant DERIVE, for the determination of the geometric characteristics of plane sections whose</p><p>contour this constituted by segments of right.…”
Get full text

Distribution patterns of HLA-A^*, B^*, DRB1^* allele groups among persons who underwent COVID-19 by L. N. Bubnova, I. E. Pavlova, A. S. Berkos, M. A. Terentyeva, T. V. Glazanova, L. V. Erokhina, E. V. Belyaeva, A. V. Chechetkin, N. S. Bashketova, I. G. Chkhindzheria, M. А. Kozhemyakina, D. V. Azarov, R. N. Kuznetsova, Areg A. Totolyan

“…At the same time, the frequency of HLA-A*29 was increased more than 2-fold (5.80% versus 2.47%, χ2 = 4.03). …”
Get full text

Soft Power of Higher Education as a Global Leadership Factor by N. L. Antonova, A. D. Sushchenko, N. G. Popova

“…It is possible to enter the Top 500 best world universities; however, the task of maintaining the achieved position in global rankings is more complicated and cannot be completed without a steady increase in the performance over several years. …”
Get full text

Uso de los residuos sólidos mineros de la extracción del níquel como estimulantes para la producción de biogás. // Use of the nickel solid mining residuals as stimulants for the bi... by I. Pereda Reyes, R. Irusta Mata, D. Oliva Terencio

“…In all cases, the<br />best answer was obtained when Cola concentration was around 3mg/l, with an organic matter removing of more than 80%.</p><p><br />Keywords: Anaerobic digestion, biogas, trace metals, mining residues.…”
Get full text

Molecular dissection of oil content with respect to fatty acid compositions by conditional QTL analysis in oilseed rape by WANG Jibian, CHEN Hongcheng, CHEN Yubo, ZHANG Xiaoyu, XU Haiming, ZHAO Jianyi

“…The numbers of QTL identified in present study for four fatty acid compositions are clearly more than that detected in populations with segregation for erucic acid content, indicating that the existence of allelic differentia in two major erucic acid gene loci might restrain or hide the expression of QTL with minor genetic effects. …”
Get full text

THE OUTCOMES OF FUNCTIONING OF THE UNIFIED SYSTEM OF INDIVIDUAL DOSE CONTROL OF THE RUSSIAN FEDERATION CITIZENS BASED ON THE 2015 DATA by A. N. Barkovsky, R. R. Akhmatdinov, N. K. Baryshkov, A. A. Bratilova, T. A. Kormanovskaya, S. I. Kuvshinnikov, L. V. Repin, I. P. Stamat, O. E. Tutelyan

“…According to the No.3-DOZ data, more than 272 mln X-ray diagnostics were conducted in theRussian Federation in 2015. …”
Get full text