Challenging the One-Size-Fits-All Approach in Rheumatoid Arthritis Management by Addressing Serostatus-Driven Differences by Andrei-Flavius Radu, Ada Radu, Carmen Delia Nistor-Cseppento, Delia Mirela Tit, Lavinia Cristina Moleriu, Nicoleta Anamaria Pascalau, Radu Dumitru Moleriu, Simona Gabriela Bungau

“…Autoantibodies like RF and ACPA correlated with more severe disease and a higher risk of unfavorable progression. …”
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Distinct patterns of osteoradionecrosis after photon-based radiotherapy and carbon ion radiotherapy for unresectable adenoid cystic carcinoma of the head and neck: case series from... by Eivind Storaas, Marta D. Switlyk, Sigrun Dahl, Cecilie D. Amdal, Åse Bratland, Thuy-Tien M. Huynh, Hanne A. Eide, Barbara Vischioni, Ester Orlandi, Einar Dale

“…Patients with ACC referred for CIRT often have a worse prognosis and more advanced disease than patients treated with photons. …”
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E3 ubiquitin ligase FBXW11-mediated downregulation of S100A11 promotes sensitivity to PARP inhibitor in ovarian cancer by Ligang Chen, Mingyi Wang, Yunge Gao, Yanhong Lv, Lianghao Zhai, Jian Dong, Yan Chen, Xia Li, Xin Guo, Biliang Chen, Yi Ru, Xiaohui Lv

“…Resistance to poly adenosine diphosphate (ADP)-ribose polymerase inhibitor (PARPi) presents a considerable obstacle in the treatment of ovarian cancer. …”
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Estimating program coverage in the treatment of acute malnutrition using population-based cluster survey methods: results from surveys in Burkina Faso, Chad, Democratic Republic of... by Grace Heymsfield, Elizabeth Radin, Marie Biotteau, Suvi Kangas, Zachary Tausanovitch, Casie Tesfai, Léonard Kiema, Wenldasida Thomas Ouedraogo, Badou Seni Mamoudou, Mahamat Garba Issa, Lievin Bangali, Marie Christine Atende Wa Ngboloko, Balki Chaïbou, Maman Bachirou Maman, Eva Leidman, Oleg Bilukha

“…We present this methodology as an alternative to existing primary methods and a complement to coverage estimates from routine program and population data.…”
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Low-density lipoprotein receptor-related protein 2 (LRP2) is required for lipid export in the midgut of the migratory locust, Locusta migratoria by Yiyan Zhao, Weimin Liu, Xiaoming Zhao, Zhitao Yu, Hongfang Guo, Yang Yang, Hans Merzendorfer, Kun Yan Zhu, Jianzhen Zhang

“…However, little is known about the role of LRP2 in lipid homeostasis in insects. In the present study, we investigated the function of LRP2 in the migratory locust Locusta migratoria (LmLRP2). …”
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Patellar motion and dysfunction of its stabilizers in a biomechanical model of the knee joint by A. S. Yurova, A. I. Tyagunova, F. B.  Loginov, Yu. V. Vassilevski, A. V. Lychagin, E. B. Kalinsky, E. V. Larina, N.  V. Gorohova, K. A. Devyatyarov, O. N. Bogdanov, I. B. Kovalenko, K. V. Chesnokova, M. A.  Dergachev, E. Yu. Mychka, O. N. Kosukhin

“…Additionally, deactivation of LR components 1 and 2 induces more medial tilt and translation. Deactivating LR components 3 and 4 leads to further lateral translation and slight additional medial tilt.Conclusion. …”
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Analysis of advanced cooling strategies for rocket engines conveying ternary hybrid nanofluids with second slip conditions and melting heat transfer by Hatem Gasmi, A.M. Obalalu, Umair Khan, Anuar Ishak, Hami Gündoğdu, Nermeen Abdullah, Samia Elattar, Ahmed M. Galal

“…Among the studied nanofluids, Graphene-Al2O3-SiO2/kerosene demonstrates superior performance compared to Copper-Al2O3-SiO2/kerosene, making it a more effective choice for applications like rocket engine cooling and fuel systems. …”
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Cost and benefit analysis of Climate-Smart Agriculture interventions in the dryland farming systems of northern Ghana by Felix KPENEKUU, Philip ANTWI-AGYEI, Fred NIMOH, Andrew DOUGILL, Albert BANUNLE, Jonathan ATTA-AIDOO, Frank BAFFOUR-ATA, Thomas Peprah AGYEKUM, Godfred ADDAI, Lawrence GUODAAR

“…There is a need for more focus in understanding the economic benefits of Climate-Smart Agriculture (CSA) interventions, particularly in sub-Saharan Africa, where extreme climate events are significantly affecting agriculture and rural livelihoods. …”
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Design of a multi-epitope vaccine against drug-resistant mycobacterium tuberculosis and mycobacterium bovis using reverse vaccinology by Eva Akurut, Yahaya Gavamukulya, Julius Mulindwa, Moses Isiagi, Ronald Galiwango, Mudarshiru Bbuye, Ibra Lujumba, Davis Kiberu, Patricia Nabisubi, Grace Kebirungi, Andrew Kambugu, Barbara Castelnuovo, Gyaviira Nkurunungi, Daudi Jjingo, Brenda Oketch, David Patrick Kateete, Gerald Mboowa

“…Abstract The global burden of Mycobacterium tuberculosis (M. tuberculosis) and Mycobacterium bovis (M. bovis), the rise of drug-resistant strains, necessitates an urgent need for developing more effective vaccines. This study employed an in-silico approach to design a multi-epitope vaccine targeting the PE_PGRS16 protein, a conserved virulence factor found across both species, including drug-resistant strains. …”
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Evaluation of screw pull-out from plate fixation of en bloc distal radius resection with ulnar reconstruction: Finite element analysis and comparison with experiments on Thiel cada... by Wares Chancharoen, Theingi Nwe, Saran Seehanam, Napawan Taradolpisut, Thewarid Berkband, Thanapon Chobpenthai, Chavin Jongwannasiri, Laphatrada Yurasakpong

“…In comparison with previous investigations that used computational modeling or fresh-frozen cadaveric specimens, in the present research, FEA predictions specifically experimentally confirm the usage of Thiel cadavers, which better preserve soft tissue elasticity and hydration, thus more closely reflect in vivo conditions. …”
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Main-oval Auroral Emission from a T6 Brown Dwarf: Observations, Modeling, and Astrometry by J. C. Guirado, J. B. Climent, J. D. Bergasa, M. A. Pérez-Torres, J. M. Marcaide, L. Peña-Moñino

“…From a series of 5 GHz Very Long Baseline Array (VLBA) radio observations taken over a 1 yr span, we present the detection of compact, highly polarized radio emission from the T6 brown dwarf WISE J112254.72+255022.2, compatible with electron cyclotron maser emission. …”
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Surface Fluorination for the Stabilization in Air of Garnet-Type Oxide Solid Electrolyte for Lithium Ion Battery by Michael Herraiz, Saida Moumen, Kevin Lemoine, Laurent Jouffret, Katia Guérin, Elodie Petit, Nathalie Gaillard, Laure Bertry, Reka Toth, Thierry Le Mercier, Valérie Buissette, Marc Dubois

“…More interestingly, contrary to the pristine LLZO, the contents of these groups are drastically reduced even after storage in air up to 45 days when the powder is covered with the LiF layer. …”
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Hybrid Capture-Based Sequencing Enables Highly Sensitive Zoonotic Virus Detection Within the One Health Framework by Weiya Mao, Jin Wang, Ting Li, Jiani Wu, Jiangrong Wang, Shubo Wen, Jicheng Huang, Yongxia Shi, Kui Zheng, Yali Zhai, Xiaokang Li, Yan Long, Jiahai Lu, Cheng Guo

“…In both sample types, our hybrid capture-based sequencing method exhibited heightened sensitivity, increased viral genome coverage, and more comprehensive viral identification and characterization. …”
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Initial Diagnostic Strategies for Helicobacter Pylori in Patients With Bleeding Peptic Ulcers Undergoing Endoscopy: A Cost-Effectiveness Analysis by Michael G. Artin, Josephine Soddano, Sheila D. Rustgi, Zainab Aziz, Francesca Lim, Jeong Yun Yang, Myles A. Ingram, John T. Nathanson, John Y. Kao, Chin Hur

“…UBT was the preferred strategy as it was both less costly and more effective than no testing. Conclusion: Our findings suggest that UBT is the cost-effective strategy to identify H. pylori in patients admitted with PUD. …”
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Application of the Original Agroecological Survey and Indicator System tool (OASIS) to organic and conventional farms in Belgium, France, and Italy by Alexander Wezel, Alexander Wezel, Paola Migliorini, Paola Migliorini, Anna Brumer, Tommaso Gaifami, Tommaso Gaifami, Angelica Marchetti, Geoffrey Floymont, Garance Guizard, Elsa Michel, Marie-Alix Renaud, Karla Škorjanc, Nicolas Allard, Stefano Bocchi, Alain Peeters, Alain Peeters, Alain Peeters

“…European agriculture faces major challenges in adapting and transforming current farming and food systems to become more sustainable. Agroecology is one transition pathway. …”
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Visual impairments associated with the treatment of malignant tumors of the female reproductive system: a literature review and practical recommendations for oncogynecologists by Y. A. Chuikova, O. A. Odintsova, D. V. Skalozub, A. G. Antonyuk, A. A. Kabartai, A. N. Nurmamatova, R. M. Azimov, P. A. Snatenkova, A. A. Silantyev, S. R. Osina, D. S. Minasyan, S. A. Lashevich, I. A. Isaeva, E. A. Rukhlyadyeva

“…In addition, it also presents differentiated approaches to diagnosing and managing ophthalmic toxicity related to the specific drug class. …”
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A comparative study of plasmonic nanoparticles for targeted photothermal therapy of melanoma tumors using various irradiation modes by Lidia Mikhailova, Elizaveta Vysotina, Maria Timofeeva, Elena Kopoleva, Van Gulinyan, Olesia Pashina, Konstantin Arabuli, Olga Gusliakova, Ekaterina Prikhozhdenko, Xiaoli Qi, Andrey Petrov, Eduard Ageev, Mihail Petrov, Constantino De Angelis, Mikhail Durymanov, Gleb Sukhorukov, Mikhail V. Zyuzin

“…Our investigation reveals greater heat release from Au NRs under irradiation with FS laser, due to the relaxation rates of the electron and phonon temperatures dissipating in the surrounding, which correlates with a more pronounced 17.6 times inhibition of tumor growth when using FS-pulsed regime.…”
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Characterizing Advanced Parkinson’s Disease: Romanian Subanalysis from the OBSERVE-PD Study by Jozsef Attila Szasz, Dragos Catalin Jianu, Mihaela Adriana Simu, Viorelia Adelina Constantin, Adriana Octaviana Dulamea, Koray Onuk, Diana Popescu, Mihai-Titus Vasile, Bogdan Ovidiu Popescu, Alfonso Fasano, Ovidiu Alexandru Bajenaru

“…Our results highlight the importance of earlier recognition of APD, by combining clinical judgement with more standardized clinical tools, such as generally recognized APD criteria. …”
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The mediating role of family adaptability in the relationship between insecure attachment and family functioning in patients with major depression disorder: a cross-sectional study by Xinlei Cheng, Xinlei Cheng, Xinfei Li, Jinlong Zhao, Jinlong Zhao, Lei Wang, Lei Wang, Xiaoning Shi, Xiaoning Shi

“…IntroductionDepression ranks as the second leading cause of the global health burden; therefore, identification of its risk and influencing factors is essential to develop more effective multidimensional interventions. The aim of the present study was to analyze the mediating role of family adaptability (FA) on the relationship between insecure attachment (IA) and family functioning (FF) in patients with major depressive disorder (MDD), which currently remains unclear. …”
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Differential responses of coolwater fishes to a whole‐lake reduction of a warmwater thermal guild by Holly S. Embke, Stephen R. Carpenter, T. Douglas Beard Jr., Giancarlo Coppola, Daniel A. Isermann, Eric J. Pedersen, Andrew L. Rypel, Christopher J. Sullivan, Tyler D. Tunney, M. Jake Vander Zanden

“…As a result, warmwater fishes are increasingly becoming more prevalent in lakes where they already existed, altering the patterning and strength of species interactions. …”
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