Robust and Sustained Effect of Ketamine Infusions Coadministered with Conventional Antidepressants in a Patient with Refractory Major Depression by José Manuel Montes, Elena Luján, Fernado Pascual, Jose María Beleña, Jose Luis Perez-Santar, Luis Javier Irastorza, Jerónimo Saiz-Ruiz

“…Electroconvulsive therapy is an alternative treatment which has been shown to be more effective but it is not well tolerated and there are concerns regarding its safety. …”
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The MentalPlus® Digital Game Might Be an Accessible Open Source Tool to Evaluate Cognitive Dysfunction in Heart Failure with Preserved Ejection Fraction in Hypertensive Patients: A... by Valeria Fontenelle Angelim Pereira, Livia Stocco Sanches Valentin

“…The results disclosed 60 hypertensive patients. All of them presented with HFpEF. Patients presented a mean age of 56±10 years; 46% male; LVMi (g/m2) mean of 110±20; educational attainment of 9 years or more; mean income of 8 Brazilian minimum wages. …”
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Out of hospital cardiac arrest in STEMI patients: A six-year review of an Irish tertiary referral centre by Gregory Offiah, Darren Dahly, Adel Shelfah, Martin O. Quinn, Siobhan Masterson, Peter Kearney, Conor Deasy

“…Conclusion: Mortality rates amongst studied STEMI patients presenting with OHCA were high. Although transfer to ED was associated with increased mortality, this finding may be explained by confounding factors, including more profound haemodynamic instability precluding STEMI diagnosis, and/or requiring transfer to ED for stabilisation.…”
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Association of Peroxisome Proliferator-Activated Receptors (PPARs) with Diabetic Retinopathy in Human and Animal Models: Analysis of the Literature and Genome Browsers by Špela Tajnšek, Danijel Petrovič, Mojca Globočnik Petrovič, Tanja Kunej

“…Results of the present analysis will enable more holistic approach for understanding of PPARs in DR development. …”
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Acute Disseminated Encephalomyelitis Following Completion of Pneumococcal Meningitis Treatment: A Case Report and Review of the Literature by Ayşe Serra ÖZEL, Lütfiye Nilsun ALTUNAL, Zakir SAKCI, Ece Aslı YILMAZ, Mesut YILMAZ, Ayten KADANALI

“…ADEM is less common in adults and progresses with a more severe clinical course. Cases diagnosed with ADEM by CNS demyelination after streptococcal meningitis have rarely been reported in adult patients. …”
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THE RESULTS OF COMPUTER MORPHOMETRY USED IN ENDOMETRIAL HYPERPLASIA by Yu. Yu. Tabakman, I. B. Manukhin, A. G. Solopova, A. A. Kanibolotsky, A. Kh. Bishtavi, O. A. Gornykh, V. V. Samoylenko, V. N. Gulieva, Kh. T. Gogoladze, N. G. Chikovani

“…Differencial diagnostics of simple, complex and atypical hyperplasia and endometrial cancer(SEH, CEH, AEH, EC) presents a number of difficulties which often lead to a different interpretation of the same histologic samples. …”
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Longer-term virologic outcomes on tenofovir-lamivudine-dolutegravir in second-line ART by Jennifer K. van Heerden, Ying Zhao, Claire M. Keene, Rulan Griesel, Zaayid Omar, René Goliath, Kayla Delaney, Gert van Zyl, Gary Maartens, Graeme Meintjes

“…Background: Dolutegravir in second-line antiretroviral therapy (ART) is more effective with recycled tenofovir than switching to zidovudine. …”
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Nanotechnology-based theranostics for bone tumors by Wenwen Zhan, Shuyan Zeng, Lin Yang, Ye-Zhong Zhang, Jing Zhang

“…Recent rapid advancements in nanotechnology have introduced diverse and more effective strategies for the management of bone tumors. …”
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Diverse diagnostic and management approaches for acute rheumatic fever in Australia and New Zealand: findings of a prospective clinical study by David Broadhurst, Bo Remenyi, Nigel J Wilson, Jonathan R Carapetis, Shirley Lawrence, Florina Chan Mow, Joshua Reginald Francis, Jennifer Yan, Anna P Ralph, Glenn Pearson, Mark Mayo, Rachel Webb, Nicole J Moreland, Reuben McGregor, Julie Bennett, Ruwani Peiris, Rachel Burgess, Alicia Stanley, Laura Francis, Rhonda Holloway, Roxanne Westbury, Yolanda Hernandez-Gomez, Caroline Motteram

“…Positive throat Group A Streptococcus culture was more common in New Zealand than in Australian participants (69% vs 3%). …”
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Depletion of conventional CD4+ T cells is required for robust priming and dissemination of tumor antigen-specific CD8+ T cells in the setting of anti-CD4 therapy by Keisuke Shirai, Tiffany Chen, Mary Jo Turk, Delaney E Ramirez, Christo P C Dragnev, Tyler G Searles, Nathaniel Spicer, J Louise Lines, Aaron R Hawkes, Wilson L Davis, Asmaa Mohamed, Joseph D Phillips, Pamela C Rosato, Yina H Huang

“…We also show that depletion of CD4-expressing antigen-presenting cell subsets is not required for anti-CD4 efficacy. …”
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Comparative analysis of echocardiographic and electrocardiographic data of survivors and deceased patients with COVID-19 (sub-analysis of the international register “Dynamics analy... by G. P. Arutyunov, E. I. Tarlovskaya, A. G. Arutyunov, Y. N. Belenkov, A. O. Konradi, Y. M. Lopatin, A. P. Rebrov, S. N. Tereshchenko, A. I. Chesnikova, A. R. Vaisberg, N. Y. Grigorieva, B. B. Ogurlieva, I. V. Fomin, I. A. Frolova, O. Yu. Badina, O. E. Vilkova, N. V. Zarechnova, N. A. Kamardina, E. V. Koroleva, K. V. Mazalov, D. V. Soloveva

“…Comparative analysis of echocardiographic data showed that deceased patients have more pronounced right heart remodeling, higher PASP and lower LVEF. …”
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Fate and risks of potentially toxic elements associated with lacustrine groundwater discharge: quantification, modeling, and biogeochemistry by Shen Qu, Juliang Wang, Keyi Zhang, Mengyu Fan, Yuanzhen Zhao, Xu Yang, Zhongli Wang, Helena I. Gomes, Rachel L. Gomes, Limin Duan, Shaogang Dong, Ruihong Yu

“…Microbial analysis revealed higher diversity (ace index = 1751 ± 577) in groundwater, while surface water PTE had a more pronounced impact on microbial functionality than groundwater (p < 0.001). …”
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Clinical analysis of patients with idiopathic pulmonary fibrosis concurrent with surgery resectable lung cancer: a retrospective cohort study from perspective of ILD physicians by Qi Chen, Yujie Shi, Ruxuan Chen, Kai Xu, Cheng Huang, Ji Li, Zhiyi Li, Mengqi Wang, Chi Shao, Hui Huang, Mengzhao Wang

“…The serum Cyfra211 level was higher and the lung cancer stage was more advanced in the non-survival group than in the survival group. …”
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Vascular contributions to cognitive impairment and dementia: Research consortia that focus on etiology and treatable targets to lessen the burden of dementia worldwide by Jordan T. Gladman, Roderick A. Corriveau, Stephanie Debette, Martin Dichgans, Steven M. Greenberg, Perminder S. Sachdev, Joanna M. Wardlaw, Geert Jan Biessels

“…Members of these multi‐institute, multidisciplinary consortia provide a prospective on the history and emerging science of VCID and how VCID consortia can address some of the more complex questions in VCID and drive the field forward. …”
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A robust data-driven approach for modeling turbulent transport by R. Varennes, Z.S. Qu, Y.W. Cho, C. Wan, K. Li, R.A. Heinonen, V. Grandgirard

“…This study highlights the importance of assessing the reliability of data-driven models, especially in view of their application to more complex high-fidelity simulations. In particular, a figure of merit is introduced to identify regions of the input space where the model’s predictions cannot be trusted. …”
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Two new records of polychaete genus Pseudonereis Kinberg, 1865 (Polychaeta: Nereididae) from Shamal Bandar (Pasni), Balochistan(Makran) coast of the Northern Arabian Sea by Qadeer Ali, Quratulan Ahmed, Eulogio Oyarzún, Ivan Marin, Hafsa Qazi, Ateeqa Baloch, Shumaila Mubarak, Iqra Shaikh, Levent Bat

“…This study has led to a better understanding of their taxonomic classification and morphological traits and has contributed to a more comprehensive understanding of the polychaete fauna in the Makran region. …”
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Enhancing vaccine effectiveness in the elderly to counter antibiotic resistance: The potential of adjuvants via pattern recognition receptors by Myunghwan Jung, Hongmin Kim, Eunsol Choi, Min-Kyoung Shin, Sung Jae Shin

“…This review demonstrates the phenomenon of immunosenescence and explores various types of adjuvants, including their mechanisms and their potential in improving vaccine effectiveness for the elderly, thereby contributing to developing more effective vaccines for this vulnerable demographic.…”
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Industrial Piping System: Design and Corrosion Protection by David Coverdale Rangel Velasco, Victor Paes Dias Gonçalves, Michel Picanço Oliveira, Noan Tonini Simonassi, Felipe Perissé Duarte Lopes, Carlos Maurício Fontes Vieira

“…The findings are intended to support industry professionals in implementing more effective measures to prevent pipeline failures and improve system reliability, while also presenting recent advances and current demands.…”
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Synthesis of micropaleontological age constraints for the reconstruction of the Tethyan realm in the Lesser Caucasus (Armenia, Karabagh) by Danelian, Taniel, Triantaphyllou, Maria, Seyler, Monique, Galoyan, Ghazar, Grigoryan, Arayik, Sosson, Marc

“…We present new biostratigraphic results from two ophiolite outcrops in Armenia. …”
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Canadian Thoracic Society Recommendations for Management of Chronic Obstructive Pulmonary Disease – 2008 Update – Highlights for Primary Care by Denis E O’Donnell, Paul Hernandez, Alan Kaplan, Shawn Aaron, Jean Bourbeau, Darcy Marciniuk, Meyer Balter, Gordon Ford, Andre Gervais, Yves Lacasse, Francois Maltais, Jeremy Road, Graeme Rocker, Don Sin, Tasmin Sinuff, Nha Voduc

“…Important summary messages for clinicians are derived from the more detailed Update publication and are highlighted throughout the document. …”
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