The Bioethics-CSR Divide by Caio Caesar Dib

“…On the side of CSR, this period represents, at first, a stronger pact between businesses and society due to more stringent environmental and consumer regulations. …”
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A review of open data for studying global groundwater in social–ecological systems by Xander Huggins, Tom Gleeson, James S Famiglietti, Robert Reinecke, Daniel Zamrsky, Thorsten Wagener, Richard G Taylor, Megan Konar, Claudia Ruz Vargas, Miina Porkka, Lan Wang-Erlandsson, Inge de Graaf, Mark Cuthbert, Sara Lindersson, Yoshihide Wada, Marc F P Bierkens, Yadu Pokhrel, Juan Rocha, Giuliano Di Baldassarre, Matti Kummu, Grant Ferguson, Abhijit Mukherjee, Min-Hui Lo, Bridget R Scanlon, Mark S Johnson, Chunmiao Zheng

“…These insights have revealed groundwater as a dynamic component of the water cycle and social–ecological systems, leading to an expansion in groundwater science that increasingly focuses on groundwater’s interactions with ecological, socioeconomic, and Earth systems. This shift presents many opportunities that are conditional on broader, more interdisciplinary system conceptualizations, models, and methods that require the integration of a greater diversity of data in contrast to conventional hydrogeological investigations. …”
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The pattern of state organization in the new constitution of Lithuania: A third way between the presidential and parliamentary systems? by Andreas Hollstein

“…Interesting conclusions are made. When it regards the present period, the author elevates as the most important the relations between the President and Seimas, apportioning these into three periods: from 1993 up to 1996, from 1996 until the end of 1997 and the election of Valdas Adamkus, and the present, the ongoing period. …”
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SBML Level 3: an extensible format for the exchange and reuse of biological models by Sarah M Keating, Dagmar Waltemath, Matthias König, Fengkai Zhang, Andreas Dräger, Claudine Chaouiya, Frank T Bergmann, Andrew Finney, Colin S Gillespie, Tomáš Helikar, Stefan Hoops, Rahuman S Malik‐Sheriff, Stuart L Moodie, Ion I Moraru, Chris J Myers, Aurélien Naldi, Brett G Olivier, Sven Sahle, James C Schaff, Lucian P Smith, Maciej J Swat, Denis Thieffry, Leandro Watanabe, Darren J Wilkinson, Michael L Blinov, Kimberly Begley, James R Faeder, Harold F Gómez, Thomas M Hamm, Yuichiro Inagaki, Wolfram Liebermeister, Allyson L Lister, Daniel Lucio, Eric Mjolsness, Carole J Proctor, Karthik Raman, Nicolas Rodriguez, Clifford A Shaffer, Bruce E Shapiro, Joerg Stelling, Neil Swainston, Naoki Tanimura, John Wagner, Martin Meier‐Schellersheim, Herbert M Sauro, Bernhard Palsson, Hamid Bolouri, Hiroaki Kitano, Akira Funahashi, Henning Hermjakob, John C Doyle, Michael Hucka, SBML Level 3 Community members, Richard R Adams, Nicholas A Allen, Bastian R Angermann, Marco Antoniotti, Gary D Bader, Jan Červený, Mélanie Courtot, Chris D Cox, Piero Dalle Pezze, Emek Demir, William S Denney, Harish Dharuri, Julien Dorier, Dirk Drasdo, Ali Ebrahim, Johannes Eichner, Johan Elf, Lukas Endler, Chris T Evelo, Christoph Flamm, Ronan MT Fleming, Martina Fröhlich, Mihai Glont, Emanuel Gonçalves, Martin Golebiewski, Hovakim Grabski, Alex Gutteridge, Damon Hachmeister, Leonard A Harris, Benjamin D Heavner, Ron Henkel, William S Hlavacek, Bin Hu, Daniel R Hyduke, Hidde de Jong, Nick Juty, Peter D Karp, Jonathan R Karr, Douglas B Kell, Roland Keller, Ilya Kiselev, Steffen Klamt, Edda Klipp, Christian Knüpfer, Fedor Kolpakov, Falko Krause, Martina Kutmon, Camille Laibe, Conor Lawless, Lu Li, Leslie M Loew, Rainer Machne, Yukiko Matsuoka, Pedro Mendes, Huaiyu Mi, Florian Mittag, Pedro T Monteiro, Kedar Nath Natarajan, Poul MF Nielsen, Tramy Nguyen, Alida Palmisano, Jean‐Baptiste Pettit, Thomas Pfau, Robert D Phair, Tomas Radivoyevitch, Johann M Rohwer, Oliver A Ruebenacker, Julio Saez‐Rodriguez, Martin Scharm, Henning Schmidt, Falk Schreiber, Michael Schubert, Roman Schulte, Stuart C Sealfon, Kieran Smallbone, Sylvain Soliman, Melanie I Stefan, Devin P Sullivan, Koichi Takahashi, Bas Teusink, David Tolnay, Ibrahim Vazirabad, Axel von Kamp, Ulrike Wittig, Clemens Wrzodek, Finja Wrzodek, Ioannis Xenarios, Anna Zhukova, Jeremy Zucker

“…We provide our perspectives on the challenges presented by these developments and how SBML Level 3 provides the foundation needed to support this evolution.…”
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Clinical, genomic, and histopathologic diversity in cerebral cavernous malformations by Jian Ren, Daochao Wang, Leiming Wang, Chendan Jiang, An Tian, Ziwei Cui, Yeqing Ren, Lisong Bian, Gao Zeng, Guolu Meng, Yongzhi Shan, Jiantao Liang, Xinru Xiao, Jie Tang, Yukui Wei, Chuan He, Liyong Sun, Yongjie Ma, Jiaxing Yu, Guilin Li, Ming Ye, Peng Hu, Jingwei Li, Ye Li, Lijian Niu, Qianwen Li, Feng Ling, Jan-Karl Burkhardt, Hongqi Zhang, Tao Hong

“…Abstract Cerebral cavernous malformations (CCMs) are hemorrhagic vascular disorders with varied clinical and radiological presentations, occurring sporadically due to MAP3K3 or PIK3CA mutations or through inherited germline mutations of CCM genes. …”
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Tricin selectively combats KRAS-mutant non-small cell lung cancer by inhibiting the PDGF-BB-induced SRC/MAPK/AP-1/PD-L1 signaling pathway and potentiating the antitumor effect of a... by Jia-Xin Li, Jia-Xin Li, Shi-Yu Tan, Li-Qi Li, Yu-Hong Zheng, Lin Zhao, Hui-Rong Zhu, Hai-Lang He, Yan-Yu Zhang, Run-Ze Li, Tian-Yu Bao, Yi-Zhong Zhang, Xiao-Man Yang, Hao Zhang, Hui-Hui Chen, Bo-Wen Wu, Xin Lin, Xiao-Sheng Lin, Xiao-Sheng Lin, Yin Cheng Lin, Xin-Bing Sui, Ying Xie, Xian-Mei Zhou, Pei-Yu Yan

“…BackgroundKRAS is a commonly mutated gene that is present in approximately 30% of NSCLC patients. Currently, the identification of effective therapies for KRAS-mutant NSCLC is difficult for reasons of the structural and biochemical characteristics of the KRAS protein. …”
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Application of a high-resolution melt assay for monitoring SARS-CoV-2 variants in Burkina Faso and Kenya by Caitlin Greenland-Bews, Sonal Shah, Morine Achieng, Emilie S. Badoum, Yaya Bah, Hellen C. Barsosio, Helena Brazal-Monzó, Jennifer Canizales, Anna Drabko, Alice J. Fraser, Luke Hannan, Sheikh Jarju, Jean-Moise Kaboré, Mariama A. Kujabi, Cristina Leggio, Maia Lesosky, Jarra Manneh, Tegwen Marlais, Julian Matthewman, Issa Nebié, Eric Onyango, Alphonse Ouedraogo, Kephas Otieno, Samuel S. Serme, Sodiomon Sirima, Ben Soulama, Brian Tangara, Alfred Tiono, William Wu, Emily R. Adams, Abdul Karim Sesay, Chris Drakeley, Feiko O. ter Kuile, Issiaka Soulama, Simon Kariuki, David J. Allen, Thomas Edwards

“…Consequently, the molecular epidemiology of SARS-CoV-2 in some LMICs is limited, and there is a need for more cost-accessible technologies to help close data gaps for surveillance of SARS-CoV-2 variants. …”
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Description of Plum Scale Immatures Stages (Sphaerolecanium prunastri (Boyer de Fonscolombe) (Hemiptera: Coccidae) by Gordana ĐUROVIĆ, Selma ÜLGENTÜRK

“…The first–instar, second–instar male and female, and third–instar female of plum scale are redescribed and illustrated. We present diameters, position, distribution, and number of pors (simple, bilocular, trilocular pores, micro–ducts, tubular ducts, spiracular disc–pores), and marginal setae in all immature stages of Plum Lecanium that have not been given descriptions from different authors previously. …”

Protecting the Autonomy of Patients with Severe Mental Illness Through Psychiatric Advance Directive Peer-Facilitation by Nicholas Karasik

“…Cocanour, "Informed Consent-It's More than a Signature on a Piece of Paper," The American Journal of Surgery 214, no. 6 (2017): 993-997, https://doi.org/10.1016/j.amjsurg.2017.09.015…”
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Challenges and Obstacles in the Development of Winter Sports Tourism in the Ski Slopes of Tehran by Siavash Imeni, Leyla Asadpour Shirazi

“…Richards (1993) found that advanced skiers focused more on skiing-related attributes such as snow quality and terrain variety, unlike inexperienced skiers who emphasized price and accommodation. …”
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The sodium-glutamate antagonist riluzole improves outcome after acute spinal cord injury: results from the RISCIS randomised controlled trial analysed using a global statistical an... by Michael G. Fehlings, Karlo M. Pedro, Mohammed Ali Alvi, Ali Moghaddamjou, James S. Harrop, Ralph Stanford, Jonathon Ball, Bizhan Aarabi, Paul M. Arnold, James D. Guest, Shekar N. Kurpad, James M. Schuster, Ahmad N. Nassr, Karl M. Schmitt, Jefferson R. Wilson, Darrel S. Brodke, Faiz U. Ahmad, Albert Yee, Wilson Z. Ray, Nathaniel P. Brooks, Jason Wilson, Diana S-L. Chow, Elizabeth G. Toups, Kevin E. Thorpe, Jiaxin Huang, Peng Huang

“…This strategy fails to adequately capture the full impact of treatment in heterogenous neurological conditions like SCI. A more patient-centric analysis requires assessment of neurological function, functional capacity, and quality of life, incorporating meaningful patient-reported outcomes. …”
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The genomic and epigenomic landscape of iridocorneal endothelial syndrome by Yaoming Liu, Gen Li, Jiaxuan Jiang, Sujie Fan, Lan Lu, Ting Wang, Guigang Li, Wenzong Zhou, Xuequn Liu, Yingjie Li, Hong Sun, Liang Liang, Yuhong Tang, Yang Chen, Jianjun Gu, Fei Li, Xiuli Fang, Tao Sun, Aiguo Lv, Yayi Wang, Peiyuan Wang, Tao Wen, Jiayu Deng, Yuhong Liu, Mingying Lai, Jingni Yu, Danyan Liu, Hua Wang, Meizhu Chen, Li Li, Xiaodan Huang, Jingming Shi, Xu Zhang, Kang Zhang, Lingyi Liang, Xiulan Zhang

“…Among these, 45 recurrent hypomethylated regions (HMRs) in more than 10% of ICE patients showed differential methylation compared to normal controls. …”
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Fusion genes in cancers: Biogenesis, functions, and therapeutic implications by Haiqiong Tang, Qiu Peng, Linda Oyang, Shiming Tan, Xianjie Jiang, Zongyao Ren, Xuemeng Xu, Mengzhou Shen, Haofan Li, Mingjing Peng, Longzheng Xia, Wenjuan Yang, Shizhen Li, Jiewen Wang, Yaqian Han, Nayiyuan Wu, Yanyan Tang, Jinguan Lin, Qianjin Liao, Yujuan Zhou

“…In recent years, the advent of sequencing technology and bioinformatics has led to the discovery of more fusion genes associated with specific types of tumors. …”
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SpecDis: Value Added Distance Catalog for 4 Million Stars from DESI Year-1 Data by Songting Li, Wenting Wang, Sergey E. Koposov, Ting S. Li, Youjia Wu, Monica Valluri, Joan Najita, Carlos Allende Prieto, Amanda Byström, Christopher J. Manser, Jiaxin Han, Carles G. Palau, Hao Yang, Andrew P. Cooper, Namitha Kizhuprakkat, Alexander H. Riley, Leandro Beraldo e Silva, Jessica Nicole Aguilar, Steven Ahlen, David Bianchi, David Brooks, Todd Claybaugh, Axel de la Macorra, John Della Costa, Arjun Dey, Peter Doel, Jaime E. Forero-Romero, Enrique Gaztañaga, Satya Gontcho A Gontcho, Gaston Gutierrez, Klaus Honscheid, Mustapha Ishak, Stephanie Juneau, Robert Kehoe, Theodore Kisner, Anthony Kremin, Martin Landriau, Laurent Le Guillou, Michael Levi, Marc Manera, Aaron Meisner, Ramon Miquel, John Moustakas, Nathalie Palanque-Delabrouille, Will Percival, Claire Poppett, Francisco Prada, Ignasi Pérez-Ràfols, Graziano Rossi, Eusebio Sanchez, David Schlegel, Michael Schubnell, Hee-Jong Seo, Joseph Harry Silber, David Sprayberry, Gregory Tarlé, Benjamin Alan Weaver, Rongpu Zhou, Hu Zou

“…We present the S pec D is value-added stellar distance catalog accompanying DESI Data Release 1. …”
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Effects of di(2-ethylhexyl) phthalate on glucose homeostasis in rats due to impaired autophagy flux of islet β cells mediated by oxidative stress by Hongyang ZHOU, Yuting HU, Xue CHEN, Yunqiang ZHOU, Liping LI, Ling LI, Herong LIU

“…In the 375 and 750 mg·kg−1 DEHP groups, the mitochondria were deformed to varying degrees, and some cristae structures disappeared, presenting vacuolization. Moreover, the chromatin condensation in the nuclei was more severe in the 750 mg·kg−1 DEHP group. …”
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Cosmogenic ³He dating of olivine with tightly retained mantle ³He, Volcano Mountain, Yukon by J. M. Mueller, J. D. Bond, K. A. Farley, B. C. Ward

“…The presence of such unusually small fluid inclusions may relate to the origin of the olivines as disaggregated peridotite xenoliths rather than the more commonly analyzed olivine phenocrysts. We circumvented this problem by step-heating powdered olivine in steps of 800, 1000, and 1400 °C. …”
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Real-world experience with the diagnosis of bile acid malabsorption (BAM) using serum 7-alpha-C4 and 48-hour stool bile acids by G. Mendoza-Domínguez, Z.M. Garrido-Santos, C. Lau, R. Balbuena, A.D. Santana-Vargas, M. Schmulson-Wasserman

“…Lastly, BAM identified by 7αC4 was more frequent in patients with previous cholecystectomy (22.7%) vs. those without (3.8%). …”
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Mapping Antimicrobial Resistance in <i>Escherichia coli</i> and <i>Klebsiella pneumoniae</i> from Complicated Urinary Tract Infections in Oman: Phenotypic and Genotypic Insights by Nawal AL Shizawi, Zaaima AL Jabri, Fatima Khan, Hiba Sami, Turkiya AL Siyabi, Zakariya AL Muharrmi, Srinivasa Rao Sirasanagandla, Meher Rizvi

“…<i>K. pneumoniae,</i> however, was more susceptible to fluoroquinolones at 47% in comparison to <i>E. coli.…”
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Differential expansion of circulating human MDSC subsets in patients with cancer, infection and inflammation by Ang Lin, Sven Brandau, Stephan Lang, Luca Cassetta, Kirsten Bruderek, Joanna Skrzeczynska-Moncznik, Oktawia Osiecka, Xiaoying Hu, Ida Marie Rundgren, Kim Santegoets, Utku Horzum, Ana Godinho-Santos, Gennadiy Zelinskyy, Thalia Garcia-Tellez, Sunčica Bjelica, Bartłomiej Taciak, Astrid Olsnes Kittang, Benedikt Höing, Michael Dixon, Verena Müller, Jochen Sven Utikal, Derya Karakoç, Kerim Bora Yilmaz, Emilia Górka, Lubomir Bodnar, Olympia Evdoxia Anastasiou, Christine Bourgeois, Robert Badura, Monika Kapinska-Mrowiecka, Mirjana Gotic, Mark ter Laan, Esther Kers-Rebel, Magdalena Król, Juan Francisco Santibañez, Michaela Müller-Trutwin, Ulf Dittmer, Ana Espada de Sousa, Güneş Esendağlı, Gosse Adema, Karin Loré, Elisabeth Ersvær, Viktor Umansky, Jeffrey W Pollard, Joanna Cichy

“…PMN-MDSC expansion was more pronounced in cancer compared with infection and inflammation. …”
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Cognitive analysis of the development of human resource competencies in line with the Fourth Industrial Revolution by Habib Zare ahmadabadi, Sayed Heidar Mirfakhraddini, Fatemeh Zamzam, somayeh amirhosseini

“…The obtained findings indicate that the index of willingness of managers and owners of companies to move towards intelligentization and the creation of smart factories is more central than other measures, and as a result, more attention should be paid to it. …”
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