Spatial Analysis of the Concentration of Knowledge-Based Firms in Iran by Najmoddin Yazdi, Mahdi Fateh-rad, Jamal Kadkhodapour, Siamak Tahmasbi

“…Additionally, larger urban populations typically offered more potential customers, a larger talent pool for skilled labor, and better access to services and amenities, all of which were attractive factors for knowledge-based companies. …”
Get full text

Unveiling the Complex Jet Dynamics in the Blazar 2021+317 through Multiepoch Very Long Baseline Interferometry Observations by Haitian Shang, Wei Zhao, Xiaoyu Hong, Leonid I. Gurvits, Ailing Zeng, Tao An, Xiaopeng Cheng

“…We present an investigation of the compact structure of the active galactic nucleus 2021+317 based on multiepoch very long baseline interferometry (VLBI) observations at 15, 22, and 43 GHz in the period from 2013 through 2024. …”
Get full text

Case Report: Successful transplantation of a living donor kidney with five renal arteries procured via laparoscopy and back-table vascular reconstruction using the recipient's inte... by Chenzhen Yu, Chenzhen Yu, Chenzhen Yu, Limin Zhang, Limin Zhang, Limin Zhang, Chunhui Lv, Chunhui Lv, Chunhui Lv, Sheng Chang, Sheng Chang, Sheng Chang, Gang Chen, Gang Chen, Gang Chen, Zhishui Chen, Zhishui Chen, Zhishui Chen, Weijie Zhang, Weijie Zhang, Weijie Zhang, Daqiang Zhao, Daqiang Zhao, Daqiang Zhao

“…While cases with up to seven renal arteries have been reported, the occurrence of kidneys with more than three renal arteries is extremely rare. …”
Get full text

Evolution of the Inner Accretion Flow and the White Dwarf Spin Pulse during the 2023 Outburst in GK Persei by Mariko Kimura, Takayuki Hayashi, Yuuki Wada, Wataru Iwakiri, Shigeyuki Sako, Martina Veresvarska, Simone Scaringi, Noel Castro-Segura, Christian Knigge, Keith C. Gendreau, Zaven Arzoumanian

“…We present our X-ray and optical observations performed by NICER, NuSTAR, and Tomo-e Gozen during the 2023 outburst in the intermediate polar GK Persei. …”
Get full text

Carfilzomib modulates tumor microenvironment to potentiate immune checkpoint therapy for cancer by Qian Zhou, Jinxia Liang, Tong Yang, Jin Liu, Bo Li, Yingchang Li, Zhenzhen Fan, Weida Wang, Wensheng Chen, Sujing Yuan, Meng Xu, Qigui Xu, Zhidong Luan, Zhongjun Xia, Penghui Zhou, Yadong Huang, Liang Chen

“…In vivo, Carfilzomib effectively rewired tumor microenvironment through reprogramming TAMs into M1‐like macrophages and shrank autochthonous lung cancers in transgenic mouse model. More importantly, Carfilzomib synergized with PD‐1 antibody to almost completely regress autochthonous lung cancers. …”
Get full text

The average accumulated effective doses (1986-2016) for the population of the settlements of the Russian Federation attributed to the zones of radioactive contamination according t... by G. Ya. Bruk, A. B. Bazyukin, A. A. Bratilova, A. Yu. Vlasov, A. V. Gromov, T. V. Zhesko, A. N. Kaduka, M. V. Kaduka, O. S. Kravtsova, I. K. Romanovich, K. A. Saprykin, V. S. Stepanov, N. V. Titov, V. A. Yakovlev

“…Nowadays, there are adout 4000 settlements with the total population of more than 1.5 million in the radioactively contaminated areas of the Russian Federation. …”
Get full text

Oral ENPP1 inhibitor designed using generative AI as next generation STING modulator for solid tumors by Congying Pu, Hui Cui, Huaxing Yu, Xin Cheng, Man Zhang, Luoheng Qin, Zhilin Ning, Wen Zhang, Shan Chen, Yuhang Qian, Feng Wang, Ling Wang, Xiaoxia Lin, David Gennert, Frank W. Pun, Feng Ren, Alex Zhavoronkov

“…In this study, we use several artificial intelligence techniques and patient-based multi-omics data to show that Ectonucleotide Pyrophosphatase/Phosphodiesterase 1 (ENPP1), which hydrolyzes STING-activating cyclic GMP-AMP (cGAMP), is a safer and more effective STING-modulating target than direct STING agonism in multiple solid tumors. …”
Get full text

Effect of cooling temperature on machinability and hole quality in cryogenic drilling of CFRP/Ti stacks by Shunuan Liu, Zhijian Meng, Shiming Liang, Tao Wang, Hao Niu, Bin Luo, Kaifu Zhang

“…Specifically, as the cooling temperature drops, Ti chips not only tend to break but also become more irregular, particularly at −50 °C, exacerbating CFRP entrance delamination and hole wall scratches. …”
Get full text

Asteroseismic Characterization of 142 Solar-like Oscillators Hosting Confirmed Exoplanets by Wen-Xu Lin, Sheng-Bang Qian, Li-Ying Zhu, Fu-Xing Li, Qi-bin Sun, Wen-Ping Liao, Ping Li, Xiang-Dong Shi, Ting Li

“…We present the largest catalog of exoplanet host stars with solar-like oscillations compiled to date, providing a powerful resource for refining stellar and planetary characterization via asteroseismology. …”
Get full text

Definitive treatment in squamous cell carcinoma of head and neck: A retrospective analysis of chemoradiotherapy in a university hospital setting by Hádila Silva Veras Sousa, Vivian Naomi Horita, Davi Magalhães Leite Novaes, Matheus Yung Perin, Daniel Naves Araújo Teixeira, Joyce Gruenwaldt, Eduardo Baldon Pereira, Carlos Takahiro Chone, Gustavo Jacob Lourenço, Ligia Traldi Macedo, Carmen Silvia Passos Lima

“…Results: Half of patients presented toxicities grade 3 or 4, with nausea/vomiting and nephrotoxicity being more common in RT and CDDP group and anemia and neutropenia in RT and Carbo group. …”
Get full text

An ACE2 decamer viral trap as a durable intervention solution for current and future SARS-CoV by Hailong Guo, Bomsoo Cho, Paul R. Hinton, Sijia He, Yongjun Yu, Ashwin Kumar Ramesh, Jwala Priyadarsini Sivaccumar, Zhiqiang Ku, Kristen Campo, Sarah Holland, Sameer Sachdeva, Christopher Mensch, Mohamed Dawod, Annalis Whitaker, Philip Eisenhauer, Allison Falcone, Rebekah Honce, Jason W. Botten, Stephen F. Carroll, Bruce A. Keyt, Andrew W. Womack, William R. Strohl, Kai Xu, Ningyan Zhang, Zhiqiang An, Sha Ha, John W. Shiver, Tong-Ming Fu

“…Lastly, this molecule is stable at ambient temperature for more than twelve weeks and can sustain physical stress from aerosolization. …”
Get full text

Co-producing a transition model of care for eating disorders: lessons learned from a multi-perspective qualitative study with young people, carers and mental health professionals by Maria Livanou, Anya Heneghan, Grace Hill, Alanta McKenzie, Marta Marlais, Francesca Marshall, Zara Smalley, Eleni Xanthopoulou, Nora Kornai, Jessica Wilks, Ailsa McKay, Jun Teh, Isabel Taylor, Charlotte Burton, Julian Baudinet

“…Abstract Background The transition from Child and Adolescent Mental Health Services (CAMHS) to Adult Mental Health Services (AMHS) presents significant challenges for young people with eating disorders and their families. …”
Get full text

Fully automated MRI‐based analysis of the locus coeruleus in aging and Alzheimer's disease dementia using ELSI‐Net by Max Dünnwald, Friedrich Krohn, Alessandro Sciarra, Mousumi Sarkar, Anja Schneider, Klaus Fliessbach, Okka Kimmich, Frank Jessen, Ayda Rostamzadeh, Wenzel Glanz, Enise I. Incesoy, Stefan Teipel, Ingo Kilimann, Doreen Goerss, Annika Spottke, Johanna Brustkern, Michael T. Heneka, Frederic Brosseron, Falk Lüsebrink, Dorothea Hämmerer, Emrah Düzel, Klaus Tönnies, Steffen Oeltze‐Jafra, Matthew J. Betts

“…DISCUSSION Although we found excellent performance, further evaluations on more diverse datasets from clinical cohorts are required for a conclusive assessment of ELSI‐Net's general applicability. …”
Get full text

Extreme Anisotropies in Deep Layers of an Exploding Star: Overabundance of Cr in the Northeastern Jet of Cassiopeia A by Vincenzo Sapienza, Marco Miceli, Masaomi Ono, Shigehiro Nagataki, Takashi Yoshida, Emanuele Greco, Salvatore Orlando, Fabrizio Bocchino

“…Core-collapse supernovae (CCSNe) drive nucleosynthesis under extreme thermodynamic conditions, and complex mechanisms are at work prompting the transport of heavy elements from deep stellar interiors into outer layers. We present spatially resolved X-ray spectroscopy of the northeastern (NE) jet of Cassiopeia A (Cas A) using the archival 1 Ms Chandra/ACIS observations, and focusing on three fingers of the jet. …”
Get full text

The Radio Spectral Energy Distribution and Star Formation Calibration in MIGHTEE-COSMOS Highly Star-forming Galaxies at 1.5 < z < 3.5 by Fatemeh Tabatabaei, Maryam Khademi, Matt J. Jarvis, Russ Taylor, Imogen H. Whittam, Fangxia An, Reihaneh Javadi, Eric J. Murphy, Mattia Vaccari

“…With a mean value of α _nt ≃ 0.7, the synchrotron spectral index flattens with both redshift and specific SFR, indicating that cosmic rays are more energetic in the early Universe due to higher star formation activity. …”
Get full text

A Facile Route Of Acid Treatment For Enhanced Performance Of Cryptomelane In Catalytic Oxidation Of Airborne Toluene by Hoang-Huy Nguyen, Nhat-Truong Truong, Thanh-Ha Ho-Vu, Dung Van Nguyen, Long Quang Nguyen, Tuyet-Mai Tran-Thuy

“…Besides, Cu-cryptomelane presented a co-existence of orthorhombic Cu(OH)2 nanorods leading to a hydrogen reduction peak centered at 180 °C for converting Cu2+ species into metallic copper. …”
Get full text

Improving the high stress abrasive wear resistance of medium carbon quenched and partitioned bainitic steel by controlling the phase transformation sequence by Qiangguo Li, Wandong Li, Mingwei Li, Minghua Su, Zhihua Hu, Hongbo Ma, Zhengyun Wang, Tong Li, Yanan Zhang

“…The results revealed that the transformation sequence of bainite followed by martensite (B-Q&P process) is more favorable for obtaining a finer multiphase microstructure comprising bainite-martensite-retained austenite than the reverse sequence of martensite followed by bainite transformation. …”
Get full text

Clinical Characteristics of Peripheral Neuropathy in Eosinophilic Granulomatosis with Polyangiitis: A Retrospective Single-Center Study in China by Zhaocui Zhang, Suying Liu, Ling Guo, Li Wang, Qingjun Wu, Wenjie Zheng, Yong Hou, Xinping Tian, Xiaofeng Zeng, Fengchun Zhang

“…Notably, ANCA positivity, arthritis or joint pain, and higher BVAS were found to be independent associated factors for PN in EGPA. Patients with PN more frequently need glucocorticoid pulses and intravenous infusion of cyclophosphamide. …”
Get full text

Differences in volatility and organoleptic characteristics of mixed and sequential fermentation of mulberry fruit juices by Weissella confusa and Pichia kudriavzevii using metabolo... by Changqi Cai, Fuchao Yan, Junhong Li, Baochang Du, Qingshen Sun, Xiaoyun Han

“…HPLC-MS analysis indicated a 52.69% increase in sour amino acids in MLF juice, with umami amino acids being 2.23 times higher compared to PWF, resulting in a more pronounced taste profile. Additionally, succinic acid, citric acid, lactic acid, tartaric acid, and malic acid exhibited reductions of 20%, 50%, 12.66%, 75%, and 43.18%, respectively. …”
Get full text

Anthocyanin-loaded complexes of glycated dual milk-derived proteins: thermal stability, storage stability, and simulated digestion by Shuangshuang Wang, Zhenzhu Li, Qingshuang Qiu, Huilin Lv, Haokun Zhang, Hang Wang, Rongzu Nie, Wupeng Ge, Peifeng Li

“…Nonetheless, their limited stability and bioavailability present significant challenges to practical applications. …”
Get full text