COLEDOCOCELE en adulto mayor: una causa inusual de pancreatitis aguda a repetición. Reporte de caso by Eduardo Segovia-Vergara, María Goitia-Inojosa, MD, Sebastián Bravo-Cuvia, MD, Renato Carrasco-Farías, MD, Rodrigo Mansilla-Vivara, MD, MHA

“…They have an incidence of 1 in 100,000-150,000 individuals, being more common in women. Twenty percent are diagnosed in adulthood and may complicate various pancreatobiliary diseases, including recurrent acute pancreatitis. …”
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Early intravenous beta-blockers injection in patients with acute STEMI: the results of the Russian registry REGION-IM by T. S. Sukhinina, M. A. Terenicheva, R. G. Gulyan, R. M. Shakhnovich, O. V. Stukalova, O. A. Saygina, I. S. Yavelov, D. V. Pevsner

“…Oral forms of BB were used to initiate therapy 61 times more often than IVF of BAB (p<0.0001). Hospital mortality among all patients with STEMI was 4.3% (n=328). …”
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Trends and factors associated with anemia among women of reproductive age in Mali: analysis of data from 2001 to 2018 Mali demographic and health surveys by Ebenezer Kwesi Armah-Ansah, Eugene Budu, Charity Oga-Omenka, Marina Kolosnitsyna

“…Multilevel regression analysis was employed, and the results were presented as adjusted odds ratio (aOR), with 95% confidence intervals (CIs) and p-values used to show the results. …”
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Riboflavin Status in Pregnancy and Its Relationship with Blood Pressure, Heart Rate and Risk of Hypertension: Findings from the OptiPREG Observational Study by Bethany Duffy, Helene McNulty, Mary Ward, Elina Psara, Emma O’Sullivan, Geraldine Horigan, Kristina Pentieva

“…Clinical riboflavin deficiency is common in low- and middle-income countries, whilst sub-optimal riboflavin status may be much more prevalent globally than generally recognized, including in high-income countries. …”
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Lassa fever prevention in Nigeria: A study of a multi-disciplinary mix of healthcare workers in a referral treatment centre in Nigeria by Osarhiemen Iyare, Sadiku Saidu, Chukwuma David Umeokonkwo, Ijeoma Nkem Okedo-Alex, Sandra Chizoba Mba, Abdulhakeem Abayomi Olorukooba

“…The majority had good knowledge of clinical presentations, the transmission of Lassa fever and Lassa fever prevention and control (316/386, 81.9%). …”
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Case Report: Multi-cancer early detection utilizing blood-based genomics: Single-institution case series of novel cancer screening by Somya Khare, Jason C. Burton, Francis De Asis, Saron Mekonnen, Mason J. Stewart-McLellan, Diana Potts, Tiffani L. Howard, Nima Nabavizadeh, Nima Nabavizadeh

“…Four of 12 were recurrent cancers in participants more than three years from cancer therapy. There were 15 signal positives without cancer diagnoses (false positives), with one patient receiving extensive work-up for possible uterus, breast or lung cancer origin. …”
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A secure end-to-end communication framework for cooperative IoT networks using hybrid blockchain system by Suresh Babu Erukala, Dimitar Tokmakov, Anoosha Perumalla, Rajesh Kaluri, Anna Bekyarova-Tokmakova, Nevena Mileva, Slavi Lubomirov

“…Hence, the proposed framework improves over existing approaches regarding linear computing complexity, increased cryptographic methods, and a more efficient consensus process.…”
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Content validity testing of the INTERMED Self‐Assessment in a sample of adults with rheumatoid arthritis and rheumatology healthcare providers by Kiran Dhiman, Marc Hall, Trafford Crump, Alison M. Hoens, Diane Lacaille, James A. Rankin, Karen L. Then, Glen Hazlewood, Cheryl Barnabe, Steven Katz, Jason Sutherland, Erika Dempsey, Claire E. H. Barber

“…Results Three main reparative themes were identified: (1) Lack of item clarity and standardisation including problems with item phrasing, inconsistency of the items and/or answer sets and noninclusive language; (2) item barrelling, where items asked about more than one issue, but only allowed a single answer choice; and (3) timeframes presented in the item or answer choices were either too long or too short, and did not fit the lived experiences of patients. …”
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Reversal of Rocuronium Induced Muscle Relaxation with Sugammadex versus Neostigmine in Patients Undergoing General Anaesthesia: A Randomised Controlled Trial by Ankur Garg, Kirti Gupta, Richa Chandra, Jyoti Pathania, Malti Agrawal

“…Conclusion: The study concluded that sugammadex reverses rocuronium-induced muscle relaxation faster and more effectively, with fewer haemodynamic changes and adverse effects compared to the neostigmine-glycopyrrolate combination. …”
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Nanomedicine: How nanomaterials are transforming drug delivery, bio-imaging, and diagnosis by Fatma Kurul, Hasret Turkmen, Arif E. Cetin, Seda Nur Topkaya

“…We investigate theranostics, where nanoparticles integrate diagnostic imaging and treatment capabilities in a single platform, enabling more effective cancer therapies through targeted drug delivery. …”
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Case Report: Role of hypoglycemia in seizure aggravation in a case of focal epilepsy: revealing a missing link between diabetes and dementia by Hiroya Ohara, Masami Yamanaka, Kiyoko Inoue, Hironori Shimizu, Naohiko Iguchi, Naohiko Iguchi, Keiko Tanaka, Abilash Valsala Gopalakrishnan, Balachandar Vellingiri, Masako Kinoshita

“…The number of evolving BIRDs per epoch was significantly higher during more severe hypoglycemia when the cut-off values were set at 60 mg/dL (2.00 ± 0.71 vs. 0.38 ± 0.70, mean ± SD, p < 0.05, Mann–Whitney U test) and 50 mg/dL (2.33 ± 0.47 vs. 0.44 ± 0.68, p < 0.05). …”
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Bisphosphonate-Conjugated Sitafloxacin for Treatment of <i>Staphylococcus aureus</i> Infection Associated with Cortical Bone Screws: Case Series in Sheep Model by Niels Vanvelk, James Tapia-Dean, Stephan Zeiter, Karen de Mesy Bentley, Chao Xie, Frank Hal Ebetino, Shuting Sun, Jeffrey Neighbors, Edward M. Schwarz, Thomas Fintan Moriarty

“…Small animal studies supported further development, but the feasibility of HBCS treatment in a more clinically relevant and larger animal model is unknown. …”
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Individual Attitude and Youth Unemployment in Nyakagyeme Sub-County Rukungiri District. by Ainamani, Viola

“…Descriptive analysis was used to determine the proportions and frequency of the variables. The results were presented in the form of frequency tables and percentages. …”
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Lilac (Syringa oblata) genome provides insights into its evolution and molecular mechanism of petal color change by Bo Ma, Jing Wu, Tian-Le Shi, Yun-Yao Yang, Wen-Bo Wang, Yi Zheng, Shu-Chai Su, Yun-Cong Yao, Wen-Bo Xue, Ilga Porth, Yousry A. El-Kassaby, Ping-Sheng Leng, Zeng-Hui Hu, Jian-Feng Mao

“…Lilac (Syringa oblata), a well-known woody ornamental plant with obvious petal color changes, is an ideal model. Here, we presented chromosome-scale genome assembly for lilac, resolved the flavonoids metabolism, and identified key genes and potential regulatory networks related to petal color change. …”
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Gut-derived bacterial flagellin induces beta-cell inflammation and dysfunction by Torsten P.M. Scheithauer, Hilde Herrema, Hongbing Yu, Guido J. Bakker, Maaike Winkelmeijer, Galina Soukhatcheva, Derek Dai, Caixia Ma, Stefan R. Havik, Manon Balvers, Mark Davids, Abraham S. Meijnikman, Ömrüm Aydin, Bert-Jan H. van den Born, Marc G. Besselink, Olivier R. Busch, Maurits de Brauw, Arnold van de Laar, Clara Belzer, Martin Stahl, Willem M. de Vos, Bruce A. Vallance, Max Nieuwdorp, C. Bruce Verchere, Daniël H. van Raalte

“…Flagellin is part of the bacterial locomotor appendage flagellum, present in gut bacteria including Enterobacteriaceae, which we show to be more abundant in the gut of individuals with T2D. …”
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Investigating an Erupting Metric-decimetric Radio Depression and Its Physical Origin by B. T. Wang, X. Cheng, J. Y. Yan, C. Xing, W. T. Fu, L. Wu, L. Deng, A. L. Lan, Y. Chen, C. Wang, M. D. Ding

“…We present direct metric-decimetric radio imaging observations of a fascinating quiescent filament eruption on 2024 March 17 using data from the DAocheng Radio Telescope, with a combination of the Solar Dynamics Observatory and the Chinese H α Solar Explorer. …”
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Roadblocks of Urinary EV Biomarkers: Moving Toward the Clinic by Marvin Droste, Maija Puhka, Martin E. vanRoyen, Monica S. Y. Ng, Charles Blijdorp, Gloria Alvarez‐Llamas, Francesc E. Borràs, Anja K. Büscher, Benedetta Bussolati, James W. Dear, Juan M. Falcón‐Pérez, Bernd Giebel, Cristina Grange, Ewout J. Hoorn, Janne Leivo, Metka Lenassi, Alicia Llorente, Fabrice Lucien, Inge Mertens, Harald Mischak, Desmond Pink, Tobias Tertel, Swasti Tiwari, Dolores Di Vizio, Peter S. T. Yuen, Natasa Zarovni, Guido Jenster, Dylan Burger, Elena S. Martens‐Uzunova, Uta Erdbrügger

“…ABSTRACT Despite remarkable interest in the biomarker potential of urinary extracellular vesicles (uEVs) and the identification of numerous promising candidates, their clinical translation still presents multiple challenges. The opportunities for successful translation are obvious, yet the main roadblocks on the way have hardly been systematically considered and more coordinated approaches are needed to overcome them. …”
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Optimizing maize systems with raised beds: boosting productivity, profitability, and sustainability by Raj Kumar Jat, Vijay Singh Meena, Vijay Singh Meena, Illathur R. Reddy, R. K. Sohane, R. N. Singh, Shubham Durgude, Suneel Kumar, S. Pazhanismy, Sunita Kumari Meena, Kumari Sharda, Susheel Singh, Rama Kant Singh, Rama Kant Singh, Seema Kumari, Seema Kumari, K. M. Singh, Govind Kumar, Amit Kumar Lenka, Asheesh Chaurasiya, Asheesh Chaurasiya, Raghubar Sahu, Raghubar Sahu, Gopal Lal Choudhary, Paras Nath, Pankaj Kumar Yadav, Abhay Kumar, Ratnesh Kumar Jha, Ujjwal Kumar, Anup Das, Anil Kumar Jha, Dhananjay Pati Tripathi, Swati Sagar

“…The raised bed planting (RBP) system was more profitable as well, where net return increased by 20% compared to the FB system. …”
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ASURA-FDPS-ML: Star-by-star Galaxy Simulations Accelerated by Surrogate Modeling for Supernova Feedback by Keiya Hirashima, Kana Moriwaki, Michiko S. Fujii, Yutaka Hirai, Takayuki R. Saitoh, Junichiro Makino, Ulrich P. Steinwandel, Shirley Ho

“…Massive stars with a zero-age main-sequence mass of more than about 10 M _⊙ explode as core-collapse supernovae (CCSNe), which play a critical role in galaxy formation. …”
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Biosynthesis of a dual growth factors (GFs) functionalized silk sericin hydrogel to promote chronic wound healing in diabetic mice by Hanxin Deng, Fangyu Wang, Yujuan Zhou, Hexu Lei, Hongji Zhou, Siyu Chen, Zihan Meng, Mengyao He, Ding Tu, He Wang, Xian Li, Qingyou Xia, Xueming Li, Feng Wang

“…However, limited resource, high cost, and instability in vivo greatly hindered their clinical applications. In present study, two silk gland bioreactor silkworm stains were generated to successfully synthesize functional silk fibers incorporating high expressions of EGF and PDGF-BB. …”
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