Cost of respiratory syncytial virus hospitalisation in Brazilian infants: a micro-costing study from the perspective of a Brazilian tertiary public hospital, 2020–2023 by Nancy Oliveira dos Santos, Solange Batista da Silva, Edgard Joseph Kiriyama, Caroline Pimenta Nunes, Luís Felipe Batista Hiar, Leonardo Henrique Fiuza de Meireles, Francisco Neves Pereira, Ancelmo Honorato Ferraz de Sousa, Lital Moro Bass, Adriana Cristina D’Ornelas, Carla Souza Behr Pitoli, Rodrigo Fernandes Alexandre, Paulo Henrique Ribeiro Fernandes Almeida, Ana Paula Flora, Daniela Vianna Pachito, Sebastian Vernal

“…Hospitalisation episodes with intensive care unit admission were significantly more expensive, with the higher costs concentrated in the younger group (< 2 months old). …”
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Assessment of bone mineral density in epileptic patients with long-term antiepileptic therapy: pilot data by N. A. Sivakova, I. V. Abramova, V. P. Rybasova, O. D. Bolshunova, E. D. Kasyanov, G. V. Rukavishnikov, M. A. Khobeysh, M. Yu. Sorokin, L. V. Lukina, N. I. Ananyeva, R. F. Nasyrova, V. A. Mikhailov, G. E. Mazo

“…One of the most unfavorable changes in bone tissue associated with anticonvulsant use is osteoporotic disorders, which result in a loss of bone density, making the bones more fragile and prone to fractures. The problem of decreased bone mineral density and frequent fractures in patients with epilepsy is an important and understudied issue that significantly reduces quality of life and involves significant economic costs for the treatment and rehabilitation of epileptic patients. …”
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Satellites unveil long-term phenological shifts and environmental drivers of algal blooms in plateau lakes of southwestern China by Hechuan Wang, Tianci Qi, Feng Chen, Jing Li, Jiachang Wei, Honghua Cao

“…In recent years, the ecosystems of plateau lakes have encountered notable challenges characterized by a surge in the frequency of algal blooms (ABs), thereby presenting a substantial threat to both human well-being and ecosystem integrity. …”
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Landslide activation during deglaciation in a fjord-dominated landscape: observations from southern Alaska (1984–2022) by J. Walden, J. Walden, M. Jacquemart, M. Jacquemart, B. Higman, R. Hugonnet, R. Hugonnet, R. Hugonnet, A. Manconi, A. Manconi, D. Farinotti, D. Farinotti

“…By showing that glacier mass loss is associated with increased landslide movement across various settings in Alaska, we suggest that glacier–landslide interactions in coastal settings deserve special attention and further substantiate the need for establishing broader and more systematic paraglacial hazard monitoring in a warming world.…”
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Efficacy and cost-effectiveness of an ACT and compassion-based intervention for women with breast cancer: study protocol of two randomised controlled trials {1} by Inês A. Trindade, Andreia Soares, David Skvarc, Diogo Carreiras, Joana Pereira, Óscar Lourenço, Filipa Sampaio, Bruno de Sousa, Teresa C. Martins, Paula Boaventura, Joana Marta-Simões, Mind Project Team, Helena Moreira

“…Methods Participants will be women diagnosed with breast cancer randomly assigned to the Mind programme or a support group intervention (active control) in a 1:1 ratio for study 1, while study 2 includes one more arm (treatment as usual; inactive control) and a 2:2:1 ratio. …”
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Association of anthropometric indices with rs9939609 FTO gene polymorphism among overweight/obese women with breast cancer: a case-control study by Huma Naqeeb, Bismillah Sehar, Sami Siraj, Ali Madi Almajwal, Bibi Hajira, MoezAlIslam Faris, Sharifa AlBlooshi, Ali Saad R. Alsubaie, Mahpara Safdar, Iftikhar Alam, Falak Zeb

“…The odds ratio for BC was 2.4 (CI = 1.09–5.3, p &lt; 0.05), indicating that women with the AA genotype were more susceptible to BC compared to those with the wild-type TT genotype. …”
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Effectiveness and Safety of Endovascular Treatment in Large Vessel Occlusion Stroke with an NIHSS Score of ≤5 Exhibiting Predominant Cortical Signs by Chulho Kim, Seung Joon Oh, Jae Jun Lee, Jong-Hee Sohn, Joo Hye Sung, Yerim Kim, Minwoo Lee, Mi Sun Oh, Kyung-Ho Yu, Hee Jung Mo, Sang-Hwa Lee

“…These findings suggest that cortical signs should be a key factor in EVT decision-making for mild stroke cases, thereby advocating for a more individualized approach in acute stroke management.…”
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Percutaneous left ventricular assist device as a short-term mechanical circulatory support before heart transplantation in patients with high pre-transplant pulmonary hypertension... by V. N. Poptsov, V. V. Slobodyanik, E. A. Spirina, N. V. Petukhov, A. K. Solodovnikova, V. Yu. Voronkov, A. A. Dogonasheva, A. A. Skokova

“…In predominantly left-ventricular (LV) dysfunction, the use of isolated coronary artery bypass, especially amidst high pulmonary hypertension (PH), seems to be a more physiological method of short-term MSC.Objective: to present the results of a series of clinical cases of the use of percutaneous left ventricular assist device (pLVAD) before HTx in potential recipients with predominantly LV dysfunction and concomitant high PH.Materials and methods. …”
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NeSyDPP-4: discovering DPP-4 inhibitors for diabetes treatment with a neuro-symbolic AI approach by Delower Hossain, Delower Hossain, Ehsan Saghapour, Ehsan Saghapour, Jake Y. Chen, Jake Y. Chen, Jake Y. Chen

“…These challenges highlight the urgent need for efficient in-silico approaches to facilitate the discovery and optimization of safer and more effective DPP-4 inhibitors.MethodologyQuantitative Structure-Activity Relationship (QSAR) modeling is a widely used computational approach for evaluating the properties of chemical substances. …”
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Tuberculosis infection control in MDR-TB designated hospitals in Jiangsu Province, China by Honghuan Song, Guoli Li, Zhuping Xu, Feixian Wang, Xiaoping Wang, Bing Dai, Xing Zhang, Jincheng Li, Yan Li, Limei Zhu

“…Background: Hospital-acquired Tuberculosis (TB) infections among healthcare workers (HCWs) and patients present a significant challenge due to the increased risk of TB infection within healthcare settings. …”
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Retinal ischemia due to different stages of atherosclerosis - insights from a retrospective study on central retinal artery occlusion by Felix Schlachetzki, Ina Feistenauer, Michael Ertl, Mustafa Kilic, Fabian Aden, David Pollinger, Horst Helbig, Christina Wendl, Karin Pfister, Lars Krenkel, Maria Andreea Gamulescu, Ralf Andreas Linker, Sibylle Wilfling

“…Methods We performed a retrospective analysis on the detailed cardiovascular risk factors and neuroimaging data in patients with IR presenting between 2009 and 2023. Based on OCCS findings, CRAO were further divided into hyperechoic (“spot sign positive”, ssCRAO) or hypoechoic CRAO (heCRAO). …”
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Bullying victimisation and perpetration and the association with mental disorders among adolescents in Kenya, Indonesia, and Vietnam: Findings from the National Adolescent Mental H... by Holly E. Erskine, Joemer C. Maravilla, Shoshanna L. Fine, Astha Ramaiya, Mengmeng Li, Amirah Ellyza Wahdi, Yohannes Dibaba Wado, Vu Manh Loi, Harvey A. Whiteford, David Lawrence, Hannah J. Thomas, James G. Scott

“…Adolescents experiencing bullying victimisation were significantly more likely to have a mental disorder than those who had not been bullied in all three countries (Kenya: aOR 2.17, 95% CI 1.50–3.15; Indonesia: aOR 3.55, 95% CI 1.47–8.59; Vietnam: aOR 4.71, 95% CI 1.82–12.21). …”
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Intravitreal Corticosteroids in the Management of Refractory Macular Edema in Birdshot Chorioretinopathy by Alves Ambrósio J, Pestana Aguiar C, Teixeira PC, Miranda V, Chibante Pedro J, Ruão M

“…Recurrent CME episodes were more pronounced in the OS, where CFT varied from 328 to 637 μm, while OD values ranged from 304 to 576 μm. …”
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Clinical, electromyographic, and biophysical characterization of the rare Nav1.4 channel mutation SCN4A L1436P by François Charles Wang, François Charles Wang, Olivier Bouquiaux, Olivier Bouquiaux, Isabelle Lievens, Bernard Lakaye, Laura Vandries, Margaux Poleur, Samira Abdou Ide, Nurcan Inci, Vincent Seutin

“…Our experimental data indicates a relatively milder biophysical phenotype for L1436P as compared to R1448H, which becomes more pronounced at lower temperatures, consistent with the clinical phenotype of a majority of patients.…”
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THE INFLUENCE OF HEART RATE VARIABILITY ON CLINICAL COURSE OF CHRONIC HEART FAILURE AND RENAL FUNCTION IN ATRIAL FIBRILLATION PATIENTS by E. A. Polyanskaya, S. V. Mironova, N. A. Koziolova

“…In patients with permanent AF comorbid with CHF of ischemic origin the risk of sudden cardiac death, estimated by SDNN, is in U-shaped relation with mean 24 hour heart rate. More prominent decrease of HRV reflecting the increase of sudden death risk was found in a range of 24 hour heart rate &gt;110 bpm. …”
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Effects of X-ray-based diagnosis and explanation of knee osteoarthritis on patient beliefs about osteoarthritis management: A randomised clinical trial. by Belinda J Lawford, Kim L Bennell, Dan Ewald, Peixuan Li, Anurika De Silva, Jesse Pardo, Barbara Capewell, Michelle Hall, Travis Haber, Thorlene Egerton, Stephanie Filbay, Fiona Dobson, Rana S Hinman

“…A total of 617 people aged ≥45 years, with and without chronic knee pain, were recruited from the Australian-wide community. Participants were presented with a hypothetical scenario where their knee was painful for 6 months and they had made an appointment with a general practitioner (primary care physician). …”
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Standards of specialized diabetes care. Edited by Dedov II, Shestakova MV (6th edition) by Ivan Ivanovich Dedov, Marina Vladimirovna Shestakova, Andrey Alexeevich Aleksandrov, Gagik Radikovich Galstyan, Olga Rafael'evna Grigoryan, Rosa Mikhailovna Esayan, Victor Yur'evich Kalashnikov, Tamara Leonidovna Kuraeva, Dmitriy Valentinovich Lipatov, Alexander Yur'evich Mayorov, Valentina Alexandrovna Peterkova, Olga Mikhailovna Smirnova, Elena Georgievna Starostina, Elena Viktorovna Surkova, Olga Yur'evna Sukhareva, Alla Yur'evna Tokmakova, Minara Shamkhalovna Shamkhalova, Ivona Renata Yarek-Martynova

“…Dear Colleagues!. We are glad to present the 6th Edition of Standards of Diabetes Care. …”
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Aspirin in the Treatment of Cancer: Reductions in Metastatic Spread and in Mortality: A Systematic Review and Meta-Analyses of Published Studies. by Peter C Elwood, Gareth Morgan, Janet E Pickering, Julieta Galante, Alison L Weightman, Delyth Morris, Mark Kelson, Sunil Dolwani

“…A mutation of PIK3CA was present in about 20% of patients, and appeared to explain most of the reduction in colon cancer mortality by aspirin. …”
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Distribution of 10-year cardiovascular disease risk levels in Mongolia: results from nation-wide health screening program by Bayarbold Dangaa, Batzorig Bayartsogt, Ariuntuya Tuvdendorj, Enkhbold Sereejav, Khurelbaatar Nyamdavaa, Damdindorj Boldbaatar, Enkhtur Yadamsuren, Otgonbat Altangerel, Oyuntugs Byambasukh, Narantuya Davaakhuu, Tumur-Ochir Tsedev-Ochir, Mijidsuren Ganbat, Munkhtulga Gantulga, Davaalkham Dambadarjaa, Oyunsuren Enebish

“…According to the CVD charts published by the WHO, about 48% (n = 17,282) of the study population had a low 10-year CVD risk (&lt;10%), 41% (n = 14,554) had a mild risk (10–20%), 12% (n = 3,502) had a moderate risk (20–30%), and 1% (n = 431) had a high risk (&gt;30%).ConclusionMore than half of the screening program participants were identified as having a 10-year CVD risk greater than 10%. …”
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The construction and evaluation of a prognostic risk score model for HCC based on MPT-related lncRNAs by Zerun Lin, Jianda Yu, Zhijian Chen, Jingyi Chen, Xiaobin Chi, Honghuan Lin, Yongbiao Chen, Yongbiao Chen

“…A preliminary discussion is presented on the potential biological significance of risk scores in HCC.…”
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