Efficacy of fenbendazole against gastrointestinal nematodes in naturally infected goats in Maputo Province, Mozambique using in vivo, in vitro and molecular assessment by Edna F.X. Guinda, Sonia M.S. Afonso, Stefan Fiedler, Eric R. Morgan, Sabrina Ramünke, Marc Borchert, Alsácia Atanásio, Bettencourt P.S. Capece, Jürgen Krücken, Georg von Samson-Himmelstjerna

“…Farmers should regularly test the efficacy of anthelmintics used and consider more sustainable worm control approaches to reduce selection for resistance.…”
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Sequential patterning of dynamic brain states distinguish Parkinson’s disease patients with mild cognitive impairments by Aaron S. Kemp, A. Journey Eubank, Yahya Younus, James E. Galvin, Fred W. Prior, Linda J. Larson-Prior

“…Parkinson’s disease (PD) is a neurodegenerative disease which presents clinically with progressive impairments in motoric and cognitive functioning. …”
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Peer-Assisted Lifestyle (PAL) intervention: a protocol of a cluster-randomised controlled trial of a health-coaching intervention delivered by veteran peers to improve obesity trea... by Stephanie L Orstad, Melanie Jay, Victoria Sweat, Sandra Wittleder, Scott E Sherman, Jeannette M Beasley, Shea Smith, Binhuan Wang, Allison Squires, Laura Wong, Yixin Fang, Paula Doebrich, Damara Gutnick, Craig Tenner

“…Introduction Among US veterans, more than 78% have a body mass index (BMI) in the overweight (≥25 kg/m2) or obese range (≥30 kg/m2). …”
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Wild Vanilla and pollinators at risk of spatial mismatch in a changing climate by Charlotte Watteyn, Charlotte Watteyn, Charlotte Watteyn, Charlotte Watteyn, Tobias Fremout, Adam P. Karremans, Koenraad Van Meerbeek, Koenraad Van Meerbeek, Steven B. Janssens, Steven B. Janssens, Steven B. Janssens, Sander de Backer, Monika M. Lipińska, Monika M. Lipińska, Monika M. Lipińska, Bart Muys, Bart Muys

“…Our models predict a decline in range overlap between animal-pollinated Vanilla species and their pollinators under climate change, and this spatial mismatch was more pronounced for species reliant on a single known pollinator (-60% to -90%). …”
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Self-Perceived Barriers to Pediatric Cancer Care in Sub-Saharan Africa: A Cross-Sectional Multinational Study by Ole Stoeter, Nikolaus C.S. Mezger, Tamara Koenig, Eric Chokunonga, Girum Tessema, Adugna Fekadu Damise, Alda Stevy Makouanzi, Esther Majaliwa, Mahine Ivanga, Bakarou Kamate, Franck Gnahatin, Sarah Nambooze, Ima-Obong A. Ekanem, Toralf Bernig, Biying Liu, Sumit Gupta, Eva Johanna Kantelhardt

“…To assess associated factors, we conducted a multivariable regression analysis presenting the results as odds ratios (ORs).RESULTSA total of 224 patients with CC was included. …”
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Resilience investments under climate change: a regional case study in Southeast Australia by Paul J. Box, Stefanos Xenarios, Stefanos Xenarios, Russell M. Wise, Russell M. Wise, Peter Heinmiller, Chandrama Sarker, Petina L. Pert, Seona Meharg, Gemma Edwards, Russell Gorddard, Sofia Azevedo, Dianne Flett, Nic Mesic, Maryam Ahmad, John Marinopoulos, Greg Parish, Jacqui Montgomery

“…The implementation becomes more challenging in the case of Nature-based Solutions for disaster resilience and climate adaptation where there are significant gaps in understanding and evidence of their effectiveness in the short and long term. …”
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High-throughput LDI MS technology decodes the distinct metabolic landscape of prostate cancer in a large-scale cohort by Xinrong Jiang, Chen Zhang, Jing Le, Jie Zhang, Shuo Cao, Xinran Xu, Xiaoming Chen, Sheng Cheng, Haitao Yu, Haofei Jiang, Ruichen Zang, Kunyu Wang, Weiwu Chen, Haobo Fan, Jianmin Wu, Yanlan Yu, Guoqing Ding

“…Abstract Background Prostate cancer (PCa) remains a leading global malignancy, yet current diagnostic reliance on prostate-specific antigen (PSA) testing is limited by suboptimal sensitivity and specificity for early-stage detection. The present study aims to establish an effective high-throughput screening technique for accurate PCa diagnosis. …”
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Nurse-community health mediator pairs: a promising model for promoting the health of populations in remote areas of the French Amazon by Mélanie Gaillet, Margot Oberlis, Bérengère Bonot, Charlène Cochet, Estelle Jacoud, Céline Michaud, Lionel Amato, Cyril Rousseau, Cécile Caspar, Bastien Boussat, Bastien Boussat, Nicolas Vignier, Nicolas Vignier, Loïc Epelboin, Loïc Epelboin, Brice Daverton

“…In response to the COVID-19 pandemic, the MPHT reached over 6,000 individuals in addition to more than 3,000 participants in a water, hygiene and sanitation education programme. …”
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Trypanosoma cruzi Mexican Strains Differentially Modulate Surface Markers and Cytokine Production in Bone Marrow-Derived Dendritic Cells from C57BL/6 and BALB/c Mice by Cecilia Gomes Barbosa, Tamires Marielem Carvalho Costa, Chamberttan Souza Desidério, Paula Tatiana Mutão Ferreira, Mariana de Oliveira Silva, César Gómez Hernández, Malú Mateus Santos, Rafael Obata Trevisan, Weslley Guimarães Bovi, Virmondes Rodrigues, Juliana Reis Machado, Luiz Eduardo Ramirez, Carlo José Freire de Oliveira, Marcos Vinícius da Silva

“…Dendritic cells (DCs) are a type of antigen-presenting cells that play an important role in the immune response against Trypanosoma cruzi, the causative agent of Chagas disease. …”
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Technical note: Water vapour climatologies in the extra-tropical upper troposphere and lower stratosphere derived from a synthesis of passenger and research aircraft measurements by P. Konjari, P. Konjari, C. Rolf, M. I. Hegglin, M. I. Hegglin, M. I. Hegglin, S. Rohs, Y. Li, A. Zahn, H. Bönisch, P. Nedelec, M. Krämer, M. Krämer, A. Petzold, A. Petzold

“…<p>This study presents a new methodology to derive adjusted water vapour (<span class="inline-formula">H₂O</span>) climatologies for the extra-tropical upper troposphere and lowermost stratosphere (UT/LMS) from regular measurements on board passenger aircraft between 1994 and 2022 within the IAGOS (In-service Aircraft for a Global Observing System) research infrastructure. …”
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HDAC7 induction combined with standard-of-care chemotherapy provides a therapeutic advantage in t(4;11) infant B-cell acute lymphoblastic leukemia by Oriol de Barrios, Ingrid Ocón-Gabarró, Mar Gusi-Vives, Olga Collazo, Ainara Meler, Paola A. Romecín, Alba Martínez-Moreno, Juan Ramón Tejedor, Mario F. Fraga, Pauline Schneider, Michela Bardini, Giovanni Cazzaniga, Rolf Marschalek, Ronald W. Stam, Clara Bueno, Pablo Menéndez, Maribel Parra

“…This treatment drives leukemic pro-B cells towards a more differentiated state and impairs aberrant proliferation in an HDAC7-dependent manner. …”
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Molecular identification of zoonotic taeniids metacestodes in several rodent species trapped in Central Europe by Tomáš Husák, Zuzana Čadková, Ondřej Máca, Ondřej Máca, Marek Kouba, Zdeňka Klimková, Richard Sehnal, Jana Nápravníková, Václava Hrabětová, Ivana Jankovská, Jaroslav Vadlejch, Iva Langrová

“…Further, we also identified co-infection by more metacestode species or haplotypes. No rodent liver samples tested were positive for Echinococcus multilocularis or Hydatigera taeniaeformis sensu stricto, either through morphological or molecular identification methods. …”
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Behaviour change interventions to promote physical activity in people with intermittent claudication: the OPTIMA systematic review by Ukachukwu O Abaraogu, Philippa Dall, Chris Seenan, Sarah Rhodes, Trish Gorely, Joanna McParland, Julie Brittenden, Ebuka M Anieto, Lorna Booth, Cathy Gormal, Jeremy Dearling, Candida Fenton, Sarah Audsley, Kimberley Fairer, Lindsay Bearne, Dawn A Skelton

“…Although some costs were presented, no studies considered the cost of implementation. …”
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Time to endovascular thrombectomy for acute ischaemic stroke in language other than English (LOTE) communities in South-Western Sydney by Dennis Cordato, Peter Thomas, Alan McDougall, Cecilia Cappelen-Smith, Christopher Blair, Nathan Manning, Jing ji, Longting Lin, Mark Parsons, Andrew K Cheung, Daniel Wardman, Chushuang Chen, Suzanne J Hodgkinson, Helen Badge, Vivek Pidugun, Timmy Pham

“…LOTE patients (50.3%) were more likely to have diabetes mellitus (30% vs 16%; p&lt;0.001) and presented with higher stroke severity (median National Institutes of Health Stroke Scale (NIHSS) 17 vs 14; p&lt;0.001). …”
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Hypocalcemia associated with adverse outcomes following severe traumatic injury in the Western Cape of South Africa: a secondary analysis of multicenter data from the Epidemiology... by Christiaan A. Rees, Jessica L. Wild, Mengli Xiao, Lani L. Finck, Jessica B. Oudakker, Hendrick J. Lategan, George Oosthuizen, Shaheem de Vries, Janette Verster, Mohammed Mayet, Lesley Hodsdon, Karlien Doubell, Leigh Wagner, L’Oreal Snyders, Denise Lourens, Elmin Steyn, Julia M. Dixon, Steven G. Schauer, Nee-Kofi Mould-Millman

“…Here, we describe adverse outcomes associated with severe hypocalcemia among a cohort of individuals presenting to emergency care following acute traumatic injury in a resource-limited setting. …”
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A survey of hormone replacement therapy use among resistance-trained women across states of menopause transition – a preliminary analysis by John Holtje, Anna Oelmann, Valeria V. Silva Ramirez, Gretchen Shelton, Landon Shannahan, Nam Nguyen, Jacey Greece, Laura Pyott, Stacy Ann Cunnington, Laurin Conlin, Vonda J. Wright, Bill I. Campbell

“…In the survey, HRT use was defined as taking estrogen or progesterone. Data is presented descriptively.Results A total of 943 subjects identified themselves as post-menopausal. …”
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Regional and whole-brain neurofunctional alterations during pain empathic processing of physical but not affective pain in migraine patients by Dan Liu, Menghan Li, Heng Jiang, Yiqi Mi, Xiaolei Xu, Yali Zhou, Yaxian Hou, Yuquan Shen, Michael Maes, Xiao Xiao, Feng Zhou, Luca Giani, Keith M. Kendrick, Benjamin Becker, Stefania Ferraro

“…Abstract Background Accumulating evidence suggests that migraine patients present abnormal brain responses to salient sensory and emotional stimuli. …”
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Presence and Evolution of Radiological Changes at 6 and 12 Months After COVID-19 Pneumonia and Their Risk Factors by Celia Roig-Martí, Antonio Navarro-Ballester, María-Pilar Fernández-García, Ignacio Pérez-Catalán, Ana Segura-Fábrega, María Varea-Villanueva, Sofía Folgado-Escudero, Germán Herrero-Rodríguez, Elena Domínguez-Bajo, Sergio Fabra-Juana, María-José Esteve-Gimeno, María-Lidón Mateu-Campos, Jorge Usó-Blasco, José-Manuel Ramos-Rincón

“…<i>Conclusions</i>: Parenchymal patterns seem to be more frequent than reticular and fibrotic patterns after COVID-19 pneumonia. …”
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Comparative analysis of data-driven models on detection and classification of electrical faults in transmission systems: Explainability, applicability and industrial implications by Chibueze D. Ukwuoma, Dongsheng Cai, Chiagoziem C. Ukwuoma, Chinedu I. Otuka, Qi Huang

“…These findings highlight the model's potential to improve fault detection accuracy and reliability, contributing to more efficient and secure energy transmission infrastructures.…”
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Combination Cyclophosphamide and Rituximab to Minimize Glucocorticoid Use in Antineutrophil Cytoplasm Antibody–Associated Vasculitis by Tania Salehi, Gavin B. Chapman, Tariq E. Farrah, Fiona A. Chapman, Dan Pugh, Robert W. Hunter, Neeraj Dhaun

“…Methods: In this retrospective, observational, cohort study, we identified patients presenting with AAV between 2011 and 2023 treated with combination cyclophosphamide and rituximab induction therapy. …”
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