Master protocols in low- and middle-income countries: a review of current use, limitations and opportunities for precision medicine by Jingky Lozano-Kuehne, Shaun Hiu, James M S Wason, Theophile Bigirumurame, Luke O Ouma, Sarah Al-Ashmori, Samuel Sarkodie, Lou Whitehead, Ann Breeze Konkoth, Dorcas Njeri Kareithi, Marzieh Shahmandi

“…Most trials were pharmaceutical industry-sponsored studies (60/102, 58.8%), conducted in oncology settings (56/102, 54.9%), currently ongoing (69/102, 67.6%) in early phase (phase I and II) settings (70/102, 68.6%) and have been planned or launched in the last 5 years (93/102, 91.2%), mainly with international collaborations in high-income countries. China was a site to more than half of all master protocols (53/102, 52%), and only a small proportion of trials (5/102, 4.9%) launched exclusively in LMICs excluding China and European middle-income countries. …”
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Bacterial profile and antimicrobial susceptibility pattern of uropathogens among suspected patients attending Bule Hora University Teaching Hospital, southern Ethiopia by Alo Edin, Dagnamyelew Tilahun, Berhanu Adula Jara, Angefa Ayele

“…Regular surveillance of uropathogenic bacteria’s sensitivity to antibiotics can help clinicians make better treatment choices. More research is needed on both gram-positive and gram-negative bacteria, focusing on the molecular characterization of resistant genes.…”
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Genetic variants in HLA-DQA1/DQB1 genes modulate the risk of gestational diabetes mellitus in a southern Chinese population by Lijie Nie, Yan Sun, Ruiqi Li, Qiulian Liang, Guocun Deng, Xinyu He, Yifei Zeng, Hui Zheng, Xinhe Xiao, Xiaodong Ding, Jian Huang, Xiangyuan Yu, Xiangyuan Yu

“…Furthermore, stratified analysis revealed that the increased GDM risk was more likely to occur in individuals with higher blood pressure and TG, and lower HDL-c levels (P<0.05). …”
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PENGARUH PERAN KEPEMIMPINAN DAN DISIPLIN KERJATERHADAP KINERJA KARYAWAN PADA PERUSAHAAN DAERAH AIR MINUM (PDAM) KABUPATEN KARAWANG by Cecep Hermana, Uswatun Nurhasanah

“…The partial influence of leadership role on employee performance is 7.6% lower than work discipline that is equal to 59.9% so it can be stated that work discipline contributes more to employee performance than leadership role. …”
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Mutational landscape and DNA methylation-based classification of squamous cell carcinoma and urothelial carcinoma by Min Ren, Midie Xu, Chen Chen, Ran Wei, Qianlan Yao, Liqing Jia, Peng Qi, Qifeng Wang, Qianming Bai, Xiaoli Zhu, Sheng Wu, Qinghua Xu, Xiaoyan Zhou

“…The methylation-based classification results of the remaining two samples were more compatible with the results of the clinical evaluation. …”
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Follow‐up of renal transplant recipients after acute COVID‐19—A prospective cohort single‐center study by Nikolina Basic‐Jukic, Ivana Juric, Vesna Furic‐Cunko, Lea Katalinic, Josipa Radic, Zrinka Bosnjak, Bojan Jelakovic, Zeljko Kastelan

“…In 47 patients (45.2%), clinical complications were present, while 74 patients (71.2%) had one or more laboratory abnormalities. …”
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PO40 | Management of paediatric patients affected by mild factor VII deficiency undergoing surgery

“…Even if the bleeding is present only in the not-treated group, the difference between the two groups was not statistically significant (p=0.29). …”
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Evaluation of Free-Living Motor Symptoms in Patients With Parkinson Disease Through Smartwatches: Protocol for Defining Digital Biomarkers by Carlos Polvorinos-Fernández, Luis Sigcha, María Centeno-Cerrato, Guillermo de Arcas, Miriam Grande, Mayca Marín, Isabel Pareés, Juan Carlos Martínez-Castrillo, Ignacio Pavón

“… BackgroundMonitoring motor symptoms in patients with Parkinson disease (PD) presents significant challenges due to the complex nature of symptom progression, variations in medication responses, and the fluctuations that can occur throughout the day. …”
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The Role of the Amygdala in Facial Trustworthiness Processing: A Systematic Review and Meta-Analyses of fMRI Studies. by Sara Santos, Inês Almeida, Bárbara Oliveiros, Miguel Castelo-Branco

“…Six articles/studies showed that posterior cingulate and medial frontal gyrus present positive correlations with increasing facial trustworthiness levels. …”
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NEUROBLASTOMAS OF MAXILLOFACIAL LOCALIZATION OF A NEWBORN CHILD by P. I. Tkachenko, M. O. Cholovskyi, O. B. Dolenko, S. O. Belokon, Y. V. Popelo

“…Attention is drawn to the difficulties encountered in establishing a clinical diagnosis, to address questions about this, it is recommended that modern, highly informative methods of examination be more widely involved in examining such children, preferably in the early stages of the disease. …”
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A channel selection methodology for enhancing volcanic SO₂ monitoring using FY-3E/HIRAS-II hyperspectral data by X. Li, L. Zhu, H. Sun, J. Li, X. Lv, C. Qi, H. Yan

“…A positive difference between near-surface atmospheric temperature and surface temperature enables the infrared band to capture more SO<span class="inline-formula">₂</span> information in the lower and middle layers. …”
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Effects of xylanase and phytase supplementation in diets containing Moringa oleifera leaf meal on intestinal morphology and the relative size and weight of internal organs of layin... by Gabriel Miranda Macambira, Carlos Bôa-Viagem Rabello, Hélia Sharlane de Holanda Oliveira, Marcos José Batista dos Santos, Apolônio Gomes Ribeiro, Oziel Saturnino Lins Júnior, Lucas Delano Nascimento de Sousa, Igor Luiz Carvalho Máximo, Lucas Rannier Ribeiro Antonino Carvalho, Odrey Mesa Fleitas

“…Xylanase, especially when combined with MOL, enhanced villus height, crypt depth, V:C ratio, and mucosal length across all intestinal segments, while phytase had more variable effects depending on diet context. …”
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Long-term conservation agriculture to enhance soil properties and quality in rice–wheat cropping system by Amit K. Dash, Mahesh C. Meena, Shrila Das, Abir Dey, Seema Sangwan, R. S. Bana, Kaustav Aditya, Md. Basit Raza, Dhaneshwar Padhan, Saloni Tripathy, Tannishtha Bardhan, H. S. Jat, Adarsh Kumar, Nadhir Al-Ansari, Ali Salem, Mohamed A. Mattar

“…Abstract Conservation agriculture (CA) presents a promising substitute to the tillage-intensive rice–wheat cropping system (RWS) prevalent in the Indo-Gangetic plains (IGPs). …”
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Morphophysiological attributes of AMF inoculated tomato (Lycopersicon esculentum Mill.) ameliorated by resorcinol, biochar and nanobiochar by Sakina Bibi, Rehman Ullah, Tanvir Burni, Zakir Ullah, Jamal Uddin, Mohammad Nur-e-Alam, Mohsin Kazi

“…The current agricultural production system cannot solve this challenge, forcing crop growth to experience more adverse conditions. To promote the long-term sustainability of crop production and reduce reliance on excessive agrochemical use, the implementation of integrated nutrient management systems that involve the combination of chemical and biological fertilizers represents an enormous challenge. …”
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Trajectory-Ordered Objectives for Self-Supervised Representation Learning of Temporal Healthcare Data Using Transformers: Model Development and Evaluation Study by Ali Amirahmadi, Farzaneh Etminani, Jonas Björk, Olle Melander, Mattias Ohlsson

“… BackgroundThe growing availability of electronic health records (EHRs) presents an opportunity to enhance patient care by uncovering hidden health risks and improving informed decisions through advanced deep learning methods. …”
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Evaluating the MPM III and SAPS III prognostic models in a war-affected, resource-limited setting: a prospective study from the Gaza Strip by Belal Aldabbour, Ahmed J. H. Elhissi, Hamza Abudaqqa, Jaser Alqrinawi, Mohammed Badran, Mohammed Sulaiman, Yousef Alsoos, Yousef Altartour, Mohammed Abulebda, Mohammed Muhaisen, Omar Alsafadi, Zuhair Assaf

“…The intense conflict in the Gaza Strip presents an opportunity to evaluate the performance of local ICUs and validate the performance of the MPM and SAPS models within a resource-limited and highly stressed healthcare system. …”
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Organizational Methods of Furniture and Their Aesthetic Relationships in Interior Design by Akram Faraedon Hamaamen, Alwand Dlshad Najib

“…Van Droh "less is more". In the 20th century, the styles were launched from the movement and contemporary trends and were characterized by many scientific and technological events that had a direct impact on aesthetic relationships in the form of architecture and interior space and then the design of furniture and styles, most notably abstract and dismantling, and pop art. …”
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Thirty years of declining stunting in Tanzania: Trends and ongoing challenges. by Ester Elisaria, Bet Caeyers, Esther Nkuba, Laura van der Erve, August Kuwawenaruwa

“…Frequencies and percentages were calculated and presented in tables and graphs as cross-sectional data points. …”
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An Explainable Machine Learning Approach for IoT-Supported Shaft Power Estimation and Performance Analysis for Marine Vessels by Yiannis Kiouvrekis, Katerina Gkirtzou, Sotiris Zikas, Dimitris Kalatzis, Theodor Panagiotakopoulos, Zoran Lajic, Dimitris Papathanasiou, Ioannis Filippopoulos

“…The results demonstrate the robustness and interpretability of tree-based methods, offering a data-driven alternative to traditional performance estimation techniques and supporting the maritime industry’s transition toward more efficient and sustainable operations.…”
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Immunotherapy in Glioblastoma: An Overview of Current Status by Sarfraz Z, Maharaj A, Venur VA, Lathia JD, Odia Y, Ahluwalia MS

“…Advances in biomarker analysis and genomics are supporting more personalized immunotherapy approaches. In addition, combination strategies involving ICIs, CAR T-cells, vaccines, and oncolytic viruses are being developed to enhance immune response. …”
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