Feasibility and acceptability of self-directed, remote dim-light melatonin onset collection in pediatric patients diagnosed with chronic pain by Nicole Tacugue, Jessica J. Love, Jessica J. Love, Jessica J. Love, Jakob M. Cherry, Jakob M. Cherry, Jacqueline Lane, Jacqueline Lane, Jacqueline Lane, Jacqueline Lane, Joe Kossowsky, Joe Kossowsky

“…With supplementary research validating this optimized approach to measure endogenous circadian phase, more specific aspects of sleep can be targeted in pain intervention strategies to further optimize clinical outcomes in a greater population of pediatric patients.…”
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Normal serum protein electrophoresis and mutated IGHV genes detect very slowly evolving chronic lymphocytic leukemia patients by Jasmine Chauzeix, Marie‐Pierre Laforêt, Mélanie Deveza, Liam Crowther, Elodie Marcellaud, Paco Derouault, Anne‐Sophie Lia, François Boyer, Nicolas Bargues, Guillaume Olombel, Arnaud Jaccard, Jean Feuillard, Nathalie Gachard, David Rizzo

“…Abstract More than 35 years after the Binet classification, there is still a need for simple prognostic markers in chronic lymphocytic leukemia (CLL). …”
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In silico evaluation of N-aryl-1,10-phenanthroline-2-amines as potential inhibitors of T. cruzi GP63 zinc-metalloprotease by docking and molecular dynamics simulations by Priscila Goes Camargo, Ramon Borges da Silva, Aline Araujo Zuma, Simon J. Garden, Magaly Girão Albuquerque, Carlos Rangel Rodrigues, Camilo Henrique da Silva Lima

“…Ligand-protein consensus docking simulations using four GOLD scoring functions revealed that N-(R-phenyl) derivatives (R = CH3, OCH3, CF3, CN, NO2, F, Cl, and Br) presented poses with higher fitness scores than the N-naphthyl ones, with the six para-substituted derivatives (Phen4, p-CH3; Phen7, p-OCH3; Phen10, p-CN; Phen14, p-F; Phen17, p-Cl; and Phen18, p-Br) being more favorable than the ortho or meta ones. …”
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Molecular genetic diagnosis and surgical management in a cohort of children with 46,XY disorders/differences of sex development by Yuenshan Sammi Wong, Yuenshan Sammi Wong, Ho Ming Luk, Ho Chung Yau, Lap Ming Wong, Sarah Wing Yiu Poon, Joanna Yuet Ling Tung, Yuk Him Tam, Yuk Him Tam

“…A total of 20/21 patients underwent one or more surgical procedures including hypospadias repair (n = 10), gonadectomy (n = 11), gonadal biopsy (n = 4), hernia repair (n = 4), orchidopexy (n = 1), and feminizing genitoplasty (n = 1). …”
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Morphological Variations of the Anterior Cerebral Artery: A Systematic Review with Meta-Analysis of 85,316 Patients by George Triantafyllou, Ioannis Paschopoulos, Katerina Kamoutsis, Panagiotis Papadopoulos-Manolarakis, Juan Jose Valenzuela-Fuenzalida, Juan Sanchis-Gimeno, Alejandro Bruna-Mejias, Andres Riveros-Valdés, Nikolaos-Achilleas Arkoudis, Alexandros Samolis, George Tsakotos, Maria Piagkou

“…The predominant variation identified was the accessory ACA (aACA) (1.99%), followed by unilateral absence of the A1 segment (1.78%), with the latter being more frequently recognized in imaging studies (<i>p</i> < 0.0001). …”
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Phenotyping the Responses to Systemic Corticosteroids in the Management of Asthma Attacks (PRISMA): protocol for an observational and translational pilot study by Simon LeClerc, Samuel Lemaire-Paquette, Simon Levesque, Pierre Larivée, Simon Couillard, Carlos Andrés Celis-Preciado, Martine Duval, Dominic O. Cliche, Andréanne Côté, Philippe Lachapelle

“…Ultimately, this pilot study will serve to plan a larger trial comparing the clinical and biological response to systemic corticosteroids according to inflammatory biomarkers, offering valuable guidance for more personalised therapeutic strategies in asthma attacks.Ethics and dissemination The protocol has been approved by the Research Ethics Committee of the CIUSSS de l'Estrie–CHUS, Sherbrooke, Quebec, Canada (#2023-4687). …”
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Domestication of the African regional biosafety and biosecurity legislative framework – Lessons learned from the first four countries: Zambia, Botswana, Lesotho, and Sierra Leone by Christine Fortunate Rebecca Mutesi, Talkmore Maruta, Noelina Nantima, Jacqueline Lichoti Kasiiti, Zikan Koroma, Kilinda Imanuel Kilie, Tsaletseng Siimane, Mosito Tsoeunyane, Maruping Maruping, Patrick Masokwane, Samantha Letsholo, Powell Chonga, Musonda Mandona, Jaures Arnaud Kenfack Noumedem, Idosie Kenfack, Patricia Nabwami, Agnes Asele, Laura Ngumama’anwi Ambe, Donewell Bangure, Bethlehem Arega, Yenew Kebede Tebeje

“…The initiative’s main objective is to improve biosafety and biosecurity (BSBS) systems in African Union Member States. This paper presents the initiative’s strategic plan for the next five years, which outlines five priority areas. …”
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Performance of a low-cost optical particle counter (Alphasense OPC-N3) in estimating size-resolved dust emission flux using eddy covariance by S. Dupont, E. Lamaud, M. R. Irvine, J.-M. Bonnefond, A. González-Romero, A. González-Romero, A. Alastuey, C. González-Flórez, X. Querol, K. Kandler, M. Klose, C. Pérez García-Pando, C. Pérez García-Pando

“…<p>The recent development of low-cost optical particle counters (OPCs) presents new opportunities for improving spatial coverage of particle concentration in the atmosphere as they are more affordable, compact, and energy efficient than traditional OPCs. …”
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Association between 45T/G Polymorphism of Adiponectin Gene and Coronary Artery Disease in an Iranian Population by Somaye Sabouri, Majid Ghayour Mobarhan, Mohsen Moohebati, Mitra Hassani, Jamal Kassaeian, Farnoosh Tatari, Fatemeh Mahmoodi-kordi, Habib A. Esmaeili, Shima Tavallaie, Roghayeh Paydar, Amirhossein Sahebkar, Shahireh Omidvar Tehrani, Gordon Ferns, Javad Behravan

“…Among 464 patients (age: 18–75 years), recruited from individuals who underwent coronary angiography, 135 patients had less than 50% reduction of coronary artery diameter and were classified as the CAD- group and 329 patients had more than 50% reduction of coronary artery diameter and were classified as the CAD+ group. …”
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Global Burden of Cardiovascular Disease Attributable to Sugar‐Sweetened Beverages in Middle‐Aged Adults: An Age‐Period‐Cohort Modelling Study by Xiao Liu, Jie Bai, Xinrui Qi, Yifan Wu, Jitao Ling, Xinyu Liu, Tiangang Song, Jing Zhang, Zhiwei Yan, Deju Zhang, Peng Yu

“…Background Cardiovascular disease (CVD) presents a significant burden among middle‐aged adults (aged 35–64). …”
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Histone Deacetylase 6 Brain PET in Amyotrophic Lateral Sclerosis‐Frontotemporal Spectrum Disorder by Greet Vanderlinden, Charles Carron, Donatienne Van Weehaeghe, Joke De Vocht, Fouke Ombelet, Pegah Masrori, Caro De Weerdt, Rebecca E. James, Lauren T. Evans, Frederick A. Schroeder, Jacob M. Hooker, Michel Koole, Janice E. Kranz, Tonya M. Gilbert, Philip Van Damme, Koen Van Laere

“…For ALS‐FTSD, reductions were more widespread in both gray and white matter. No differences in VT were found between pwALS with and without a C9orf72 mutation. [18F]EKZ‐001 VT was not correlated with ECAS scores, age, or disease duration. …”
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Dynamic mechanical stimulation of alveolar epithelial-fibroblast models using the Flexcell tension system to study of lung disease mechanisms by Safiya Al Yazeedi, Tony Ju Feng Guo, Tony Ju Feng Guo, Joban Sohd, Filsan Ahmed Abokor, Janaeya Zuri Baher, Logan Yee, Chung Cheung, Don D. Sin, Emmanuel Twumasi Osei, Emmanuel Twumasi Osei

“…We developed mechanically strained 2D and more complex three-dimensional (3D) alveolar epithelial-fibroblast co-cultures and organoids using the Flexcell cell stretching bioreactor. …”
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Systematic literature review and trial-level meta-analysis of aromatase inhibitors vs tamoxifen in patients with HR+/HER2− early breast cancer by Wolfgang Janni, Michael Untch, Nadia Harbeck, Joseph Gligorov, William Jacot, Stephen Chia, Jean-François Boileau, Subhajit Gupta, Namita Mishra, Murat Akdere, Andriy Danyliv, Giuseppe Curigliano

“…Conclusions: This trial-level meta-analysis demonstrated a significant DFS benefit with AI vs TAM for patients with HR+/HER2− EBC, which was more pronounced in premenopausal women.…”
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In vitro model of retinoblastoma derived tumor and stromal cells for tumor microenvironment (TME) studies by Emily Alefeld, André Haase, Dario Van Meenen, Bettina Budeus, Oliver Dräger, Natalia Miroschnikov, Saskia Ting, Deniz Kanber, Eva Biewald, Nikolaos Bechrakis, Nicole Dünker, Maike Anna Busch

“…RB tumor cells cultivated in serum containing medium were more differentiated compared to RB tumor cells grown in serum-free medium displaying a stem cell like phenotype. …”
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Identification of microbial exopolymer producers in sandy and muddy intertidal sediments by compound-specific isotope analysis by Hubas, Cédric, Gaubert-Boussarie, Julie, D’Hondt, An-Sofie, Jesus, Bruno, Lamy, Dominique, Meleder, Vona, Prins, Antoine, Rosa, Philippe, Stock, Willem, Sabbe, Koen

“…Our study reveals that EPS sources are more diverse in sandy sediments than in muddy sediments. …”
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Successful treatment of severe monkeypox case with advanced HIV infection using plasma from smallpox‐vaccinated healthy population: A case report by Chuming Chen, Weiming Yao, Siran Huang, Ling Peng, Shiyan Feng, Weibo Wu, Yunlan Yi, Zhiqiang Cheng, Yang Yang, Yan Yang, Liuqing Yang, Hongzhou Lu, Fuxiang Wang

“…In this study, we report a case of severe monkeypox in a patient with HIV. The patient presented with skin lesions that started on his face and around the penis and persisted for several months. …”
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Evaluación del riesgo de ruptura de aneurismas de aorta abdominal personalizados mediante factores biomecánicos/Patient-specific abdominal aortic aneurysms rupture risk assessment... by Ariel Zúñiga‐Reyes, Leorlen Rojas‐Mazaira, Guillermo Vilalta‐Alonso, María Elena Montesinos‐Otero, Jayme Pinto‐Ortiz, Melchor Rodríguez‐Madrigal, Carlos Vaquero

“…The AAA rupture is mostly associated with fatal consequences. The lack of more reliable criteria for rupture riskassessing, results in a problem in the clinical management of the disease. …”
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Surviving Japan – An Insider’s View of the Land of Bushido by Marko Lukić

“…The strongly titled chapters “Core Concepts of Bushido” and “Killing as an Art Form” necessitate a lighter narrative tone not only due to the attempt to simplify complex philosophical and existential paradigms, but also to more successfully expose the intricate cultural undertones which characterize Japanese martial traditions. …”
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Mapping the Epidemiologic Features of Endotracheal Tube ObstructionTake-Home Points by Vimal Bhardwaj, MD, FNB(Critical Care), EDIC, Abhishek Samprathi, MD, DrNB, EDIC, Manu M.K. Varma, MD, DM, Kingshuk Saha, MSc, Ross Prager, MD, John Basmaji, MD, Nicolas Orozco, MD, Srirang Ramamoorthy, MSc, Jose Chacko, MD, EDIC, Arjun Alva, MD

“…Interpretation: Moderate ETB was more prevalent in patients in the ICU, with significant factors including coagulopathy, closed suction practice, and mechanical ventilation duration. …”
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Personality Type D and Psychophysiological Stress Reactivity During Mental Stress in Young Healthy Individuals by Alexey N. Sumin, Natalia N. Zagorskaya, Anna V. Shcheglova, Anatoly A. Shipilov, Daniil Z. Kostylbaev, Elena A. Shikanova, Ingrid Y. Prokashko

“…Individuals with type D personality showed more pronounced sympathetic activation in response to mental stress and a slower recovery at rest. …”
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