Effect of Ticagrelor on Glycaemic Parameters and Inflammatory Mediators in High Fat Diet and Streptozotocin Induced Diabetic Rats: An Experimental Study by Sachin Patel, Nayana K Hashilkar, Vidya Mahalmani

“…Furthermore, ticagrelor (35 mg/kg) was found to be more efficacious across all trial variables compared to Ticagrelor (16.2 mg/kg).…”
Get full text

Risk Factors for Multidrug-resistant Tuberculosis by Cleopas Martin Rumende

“…There is higher chance of TB bacilli persistence to be present in sputum of pulmonary TB patient with DM than TB-only patient after 5 months treatment, and this persistence made it necessary for more longer treatment. …”
Get full text

Cirque Hors Piste à l’ère Covid-19 : une histoire de contraintes et d’opportunités by Mathilde Eva Perahia

“…Lastly, the article aims to offer a broader reflection on the future of CHP, and more generally on the place of social circus in the future of the circus world.…”
Get full text

UNDERSTANDING EDUCATORS’ EXPERIENCE AND ATTITUDE TO GAMIFIED LEARNING APPLICATIONS by Anastasiia V. Tokarieva, Inna V. Сhyzhykova

“…The ability of GLAs to motivate, entertain and to create “communities of learning” are on the second place according to our data; 4) more than a half of the interviewed educators expressed their willingness to use gamified learning applications in their practice. …”
Get full text

Blade optimal design parameters determination by N. T. Surashov, R. B. Asmatulaev, D. N. Tolymbek

“…Increasing the blade height allows more material to be moved and reduces spillage through the top of the blade. …”
Get full text

MODERN METHODS OF DIAGNOSIS AND TREATMENT IN PATIENTS WITH DENTITION DEFECTS COMPLICATED OF DISORDERS OF THE TEMPOROMANDIBULAR JOINT by R. Ozhohan, M. Rozhko, Z. Ozhohan

“…About periodontal treatment in general included 70%, but about more detailed inspection was only 28.3%. About preorthodontic treatment was 33.3% and young patients in details was only 21.7%.The largest percentage amounted the information about the orthopedic treatment was 83.3%, and in details aware the features about the previous orthopedic treatment was 61.7% of patients. …”
Get full text

Prevalence of oral HPV infection and genotype distribution in Iranian children during the early ages of life by Mona Sadat Larijani, Amir Javadi, Alireza Fahimzad, Rahim Soleimani, Farbod Tabatabaei, Amir Houshang Nejadeh, Mahboubeh Jamshidi, Anahita Bavand, Ladan Moradi, Fatemeh Ashrafian, Amitis Ramezani

“…Conclusion The present research indicates that oral HPV infection is quite common in early ages of Iranian children. …”
Get full text

FIELDING’S “AMELIA”. THEMATIC PLURALITY OF THE NOVEL by Svetlana A. Vatchenko

“…According to the declared problem the author of the present article uses historical and literary, sociocultural and hermeneutic approaches in the synthesis with the technique of close reading…”
Get full text

Development of prediction models for screening depression and anxiety using smartphone and wearable-based digital phenotyping: protocol for the Smartphone and Wearable Assessment f... by Sujin Kim, Ah Young Kim, Yu-Bin Shin, Seonmin Kim, Min-Sup Shin, Jinhwa Choi, Kyung Lyun Lee, Jisu Lee, Sangwon Byun, Heon-Jeong Lee, Chul-Hyun Cho

“…The findings will be presented at local, national and international conferences in relevant fields, such as psychiatry, psychology and digital health. …”
Get full text

GEOGRAPHICAL RELATIONS OF DARKLING BEETLES (COLEOPTERA: TENEBRIONIDAE) OF THE PALAEARCTIC TETHYS DESERT-STEPPE REGION WITH THE HISTORICAL REVIEW by G. M. Abdurakhmanov, M. V. Nabozhenko, A. G. Abdurakhmanov, Yu. Yu. Ivanushenko, M. G. Daudova

“…Two early allocated super-regions are more or less clearly revealed on all dendrograms. …”
Get full text

Rice kernel morphometrics: Exploring the physical dimensions of indigenous traditional landrace diversity through physio metric studies by S. Manju Devi1, M. Raveendran2, R. Pushpam3, S.Muthuramu4, R. Pushpa5, N. Sritharan6, R. Suresh6 and A. John Joel1*

“…During cooking, grain expands in all the dimensions but usually more in length. The gelatinization temperature based on alkali digestion values showed that 16 rice genotypes had low alkali spreading values, leading to stickier rice. …”
Get full text

The association of a single-nucleotide variant in the microRNA-146a with advanced colorectal cancer prognosis by Jéssica Silva dos Santos, Gabriella Lucatto Zunta, Amanda Binatto Negrini, Marina Silva Guinda Ribeiro, Carlos Augusto Real Martinez, Marcelo Lima Ribeiro, Gustavo Jacob Lourenço, Manoela Marques Ortega

“…However, patients with tumors in advanced stage with miR-146a GG genotype had 2.41 more chance of dying than GC or CC genotypes. In addition, tumor tissues of patients with GG genotype presented higher miR-146a ( p  = 0.02) and lower BRCA1 ( p  = 0.01) and BRCA2 ( p  < 0.0001) levels when compared to those with GC or CC genotypes. …”
Get full text

Effectiveness of Radiomics-Based Machine Learning Models in Differentiating Pancreatitis and Pancreatic Ductal Adenocarcinoma: Systematic Review and Meta-Analysis by Lechang Zhang, Dewei Li, Tong Su, Tong Xiao, Shulei Zhao

“…However, systematic evidence supporting the feasibility of these models is insufficient, presenting a notable challenge for clinical application. …”
Get full text

Experiences of People Diagnosed with High Levels of LDL Cholesterol and Atherosclerotic Cardiovascular Disease: Results from a Multinational Qualitative Study by Neil Johnson, Joe Vandigo, Fernanda de Carvalho, Celina Gorre, Tanya Hall, Susan E. Hennessy, Dhruv S. Kazi, Kornelia Kotseva, Patsy Petrie, David Kelly, Ankita Saxena, Elisabeth M. Oehrlein

“…Patients’ qualitative insights about experiences, priorities, and needs are essential for creating more targeted, patient-centered quality improvement interventions. …”
Get full text

Detection of EGFR Mutations (Ex19Del, T790M, S768I, C797S, Ex20ins, G719X, L858R, L861Q) in Non-small Cell Lung Carcinoma and its Association with Various Clinicopathological Param... by Aditya A Mundra, Abha Mathur, Ram Mohan Jaiswal, Maneesh Vijayvargiya, Neha Sethi, Manoj Sharma, Shweta Bansal, Shikha Goyal

“…Conclusion: Adenocarcinomas are more commonly seen in non smoking females. Exon 19 deletion is the most common type of EGFR mutation seen in lung adenocarcinomas. …”
Get full text

Prevention of Infectious Complications in Acute Pancreatitis by A. A. Kashintsev, A. A. Zavrajnov, N. Yu. Kokhanenko, V. Yu. Proutski, I. A. Solovyev, A. A. Nadeeva, M. V. Antipova, E. L. Belyaeva, O. V. Zaitsev, M. A. Ilyina, A. V. Koshkina, V. Yu. Podshivalov, M. A. Protchenkov, Yu. V. Radionov, D. B. Rusanov, Yu. A. Pakhmutova, A. M. Spirina, A. Yu. Boyarko, G. G. Nakopia, D. V. Shankin, O. G. Vavilova

“…Several Russian clinics are currently conducting the research approved by local ethics committees. This article presents preliminary results from the data analysis. …”
Get full text

MUSEQuBES: The Column Density, Covering Fraction, and Mass of O vi-bearing Gas in and Around Low-redshift Galaxies by Sayak Dutta, Sowgat Muzahid, Joop Schaye, Nicolas F. Bouché, Sebastiano Cantalupo, Hsiao-Wen Chen, Sean Johnson

“…We present a study of O vi -bearing gas around 247 low-mass (median ${\mathrm{log}}_{10}({M}_{\star }/{M}_{\odot })$ = 8.7) galaxies at low redshifts (0.1 < z < 0.7) using background quasars as part of the MUSE Quasar-fields Blind Emitters Survey (MUSEQuBES). …”
Get full text

Development and Application of a Senolytic Predictor for Discovery of Novel Senolytic Compounds and Herbs by Jinjun Li, Kai Zhao, Guotai Yang, Haohao Lv, Renxin Zhang, Shuhan Li, Zhiyuan Chen, Min Xu, Naixue Yang, Shaoxing Dai

“…Additionally, voclosporin was found to extend the lifespan of <i>C. elegans</i> more effectively than metformin, demonstrating the value of our model for drug repurposing. …”
Get full text

The need for advancing algal bloom forecasting using remote sensing and modeling: Progress and future directions by Cassia B. Caballero, Vitor S. Martins, Rejane S. Paulino, Elliott Butler, Eric Sparks, Thainara M. Lima, Evlyn M.L.M. Novo

“…Under current climate change scenarios, algal blooms may become more frequent and intense, and it is crucial to continuously develop and advance algal bloom research to support coastal and inland water management.…”
Get full text

High angular resolution diffusion-weighted imaging and higher order tractography of the white matter tracts in the anterior thalamic area: Insights into deep brain stimulation targ... by Ruhunur Özdemir, Kai Lehtimäki, Eetu Siitama, Timo Möttönen, Joonas Haapasalo, Soila Järvenpää, Hannu Eskola, Jukka Peltola

“…A hypothetical model of neuronal networks affected by different DBS lead contact locations is proposed. A more profound understanding of neuroanatomic characteristics may guide stereotactic implantation and subsequent programming to optimize outcomes.…”
Get full text