Immune-Mediated Hemolytic Anemia in Cats with Feline Infectious Peritonitis by Petra Černá, Marieke Knies, Marleen Assink, Samantha Evans, Séverine Tasker, Danièlle A. Gunn-Moore, Katrin Hartmann, Katharina Buchta, Samantha Taylor, Solène Meunier, Regina Hofmann-Lehmann, Nicole Jacque, Allison Koonce, Casandra Jacobs, Ashley Gillett, Michael R. Lappin

“…Although FIP is likely an uncommon cause of associative IMHA, as more cats with FIP are treated with antiviral therapy, it is important to consider IMHA as a possible cause of anemia in cats with FIP.…”
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Efficacy of asfotase alfa in a patient with adult-onset hypophosphatasia without obvious bone lesions: a case report with review of literature by Seiji Nishikage, Masaaki Yamamoto, Takahiro Niikura, Yuiko Inaba, Tomoyuki Akiyama, Risa Harada, Yoshitada Sakai, Kenji Sugawara, Kanako Tachikawa, Toshimi Michigami, Wataru Ogawa, Hidenori Fukuoka

“…We report the case of a 41-year-old woman with a history of Graves’ disease, who presented with progressive joint pain and severe fatigue. …”
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Isolation and Characterization of a Cold-Adapted Bacteriophage for Biocontrol of <i>Vibrio parahaemolyticus</i> in Seafood by Zhixiang Nie, Xiangyu Cheng, Shengshi Jiang, Zhibin Zhang, Diwei Zhang, Hanfang Chen, Na Ling, Yingwang Ye

“…Critically, XY75 reduced <i>V. parahaemolyticus</i> in salmon by more than 5.98 log CFU/g (99.9%) within 6 h at 4 °C, demonstrating exceptional cold tolerance and lytic activity. …”
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The Small Separation A-star Companion Population: Tentative Signatures of Enhanced Multiplicity with Primary Mass by Matthew De Furio, Tyler Gardner, John D. Monnier, Michael R. Meyer, Kaitlin M. Kratter, Cyprien Lanthermann, Narsireddy Anugu, Stefan Kraus, Benjamin R. Setterholm

“…We present updated results from our near-infrared long-baseline interferometry (LBI) survey to constrain the multiplicity properties of intermediate-mass A-type stars within 80 pc. …”
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Long-Term Outcomes of Mild Paravalvular Leak Following Transcatheter Aortic Valve Replacement by Akiva Rosenzveig, MD, Shivabalan Kathavarayan Ramu, MD, Besir Besir, MD, Tamari Lomaia, MD, Judah Rajendran, MD, Osamah Badwan, MD, Ankit Agrawal, MD, Grant Reed, MD, MSc, James Yun, MD, PhD, Rishi Puri, MD, PhD, Amar Krishnaswamy, MD, Samir R. Kapadia, MD

“…Results: Mild PVL was present in 140 patients (5%). Compared to those with no/trace PVL, these patients were older, had a lower body mass index, higher prevalence of concentric left ventricular hypertrophy, and more frequent significant mitral regurgitation. …”
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The Monitoring of European Territorial Cooperation Projects in Italy: Critical Aspects and Innovative Solutions by Viviana Russo, Filippo La Vecchia, Agostina Rita Rocca, Simona Trento, Paolo Galletta

“…In addition, more than half of the funded projects with Italian participation have an Italian Lead Partner. …”
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Biogenic CuO nanoparticles from Camellia sinensis and Pimpinella anisum plant extracts and their role as antimicrobial agents by André Paganotti, Carolina Cunha de Freitas, Roney H. Pereira, Vitor Gonçalves Vital, Giovanna S.M. Paiva, Lucas F. de Lima, Leonardo Longuini da Silva, Elizabeth Teodorov, Ricardo A. Galdino da Silva, Suzan Pantaroto de Vasconcellos, Amedea Barozzi Seabra

“…At the MIC concentration the nanoparticles inhibited 30 % of the bacterial cells of P. aeruginosa biofilm, and at higher concentrations, the CuO NPs achieved complete inhibition, i.e. more than 99 % of the cells. In these concentrations, the nanoparticles did not present significant cytotoxicity to mammal cells. …”
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Performance Evaluation of the New High-Sensitivity Cardiac Troponin I Immunoassay on CL-2600i Mindray Analyzer by Flaminia Tomassetti, Denise Fiorelli, Edoardo Cappa, Alfredo Giovannelli, Martina Pelagalli, Silvia Velocci, Eleonora Nicolai, Marilena Minieri, Marco Alfonso Perrone, Sergio Bernardini, Massimo Pieri

“…The new technology, with more sensitive detection methods, may improve the accuracy and reliability of cardiac biomarker testing, ultimately leading to better outcomes in the management of patients with AMI and other cardiac conditions.…”
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Redo axillary artery cannulation in aortic reoperations: Technical variations and implications for optimal outcomesCentral MessagePerspective by Suguru Ohira, MD, PhD, Gabrielle Amar, BA, Sooyun Caroline Tavolacci, MD, MSCR, Masashi Kai, MD, Ramin Malekan, MD, Junichi Shimamura, MD, PhD, Steven L. Lansman, MD, PhD, David Spielvogel, MD

“…Objectives: Recannulation of the right axillary artery (Redo-AX) is a valuable yet underutilized technique in aortic reoperations. The present study sought to analyze the outcomes of 1 of the largest redo AX cannulations experiences. …”
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The Emotional Anatomy of Diagnosis: A Medical Humanities Approach to Empathy in Pathology by Iuliu Gabriel Cocuz, Raluca Niculescu, Maria Cătălina Popelea, Adrian-Horațiu Sabău, Maria-Elena Cocuz, Martin Manole, Alexandru-Constantin Ioniță, Giordano Altarozzi, Maria Tătar-Dan, Ovidiu Simion Cotoi, Dorina Maria Pașca

“…<b>Conclusions:</b> Empathy is present and relevant in pathology, despite the absence of direct patient interaction. …”
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Hotspotters Project: a study protocol for a stepped wedge cluster RCT on the cost-effectiveness of 12-month proactive, integrated and personalised care for patients with problems o... by Mattijs E Numans, Marc Abraham Bruijnzeels, Rimke C Vos, Elske M van den Akker-van Marle, Mark van der Wel, Vera Tiemes, Kimberley A Leming, Hanneke Borgdorff, Laurens C van Gestel, Marieke A Adriaanse

“…We plan to include 200 patients with (a) problems on two or more life domains and (b) at least two acute care encounters in the previous year. …”
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Protocol for a systematic review and meta-analysis of the prevalence of viral infections in acute apical abscesses by José Ángel Hernández-Mariano, Gustavo Adolfo Sánchez-Ramírez, Guillermo Cano-Verdugo, Myriam Angélica De la Garza-Ramos, Martín Andrés Chávez- Méndez, Claudio Peña-Soto, Mónica Alethia Cureño-Díaz

“…By elucidating the prevalence of viral infections, the findings of this study could enhance diagnostic accuracy and inform more targeted and effective treatment strategies, ultimately improving patient outcomes.…”
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Outcome of SARS-CoV-2 reinfection depends on genetic background in female mice by Gagandeep Singh, Juan García-Bernalt Diego, Prajakta Warang, Seok-Chan Park, Lauren A. Chang, Moataz Noureddine, Gabriel Laghlali, Yonina Bykov, Matthew Prellberg, Vivian Yan, Sarabjot Singh, Lars Pache, Sara Cuadrado-Castano, Brett Webb, Adolfo García-Sastre, Michael Schotsaert

“…K18-hACE2 CD11c+ cells show a strong antiviral defense expression profile whereas 129S1 CD11c+ cells present a more pro-inflammatory response upon restimulation. …”
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Chemokine and Cytokine Cascade Caused by Skewing of the Th1-Th2 Balance Is Associated with High Intracranial Pressure in HIV-Associated Cryptococcal Meningitis by Lijun Xu, Yongzheng Guo, Yizhou Zhao, Yufan Xu, Xiuming Peng, Zongxing Yang, Ran Tao, Ying Huang, Yan Xu, Yaokai Chen, Biao Zhu

“…Conclusion. Overall, the present findings indicated that both pro- and anti-inflammatory cytokines of Th1, Th2, and macrophage origin contributed to the development of HCM. …”
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17β-Estradiol Attenuates LPS-Induced Macrophage Inflammation In Vitro and Sepsis-Induced Vascular Inflammation In Vivo by Upregulating miR-29a-5p Expression by Man-li Zhang, Hui Chen, Zhan Yang, Man-na Zhang, Xia Wang, Kun Zhao, Xuan Li, Nan Xiu, Fei Tong, Ya-xuan Wang

“…Treating RAW 264.7 cells with E2 markedly upregulated the miR-29a-5p expression level. More importantly, we demonstrated that miR-29a-5p repressed NLRP3 expression by directly targeting its 3′-UTR. …”
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Sampling effort for community composition higher by a magnitude compared to species richness in passive acoustic monitoring by Kim Lindner, Sascha Rösner, Dana G. Schabo, Hicham Bellafkir, Markus Vogelbacher, Markus Mühling, Daniel Schneider, Nicolas Friess, Stephan Wöllauer, Bernd Freisleben, Nina Farwig

“…Our study demonstrates the relative importance of greater sampling effort especially for monitoring community composition, requiring more recording locations, duration and intervals in comparison to species richness. …”
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Impact of diabetes mellitus type-2 on the outcomes following mitral transcatheter edge-to-edge repair (TEER): A meta-analysis by Himaja Dutt Chigurupati, Sivaram Neppala, Rahul Chikatimalla, Ayman Fath, Prakash Upreti, Jeffery Bolte, Muhammad Abdullah Naveed, Adishwar Rao, Osama Altaee, Yasar Sattar, Rupak Desai, Ralph A. DeFronzo, Jamal S. Rana, Timir K. Paul

“…Patients with DM were more likely to be obese compared to patients without DM. …”
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Characterization and functional evaluation of JS207, a novel bispecific antibody against human PD-1 and VEGFA by Shihua Lin, Min Hong, Jing Zhang, Wenting Zhao, Ke Li, Chun Wu, Qiuyun Yang, Yi Xiao, Lanqing Huang, Jing Wang, Aijuan Jia, Xujia Wang, Sheng Yao

“…While combining PD-1 and VEGF inhibition has shown promise in enhancing antitumor responses, co-administration of two or more monoclonal antibodies face several challenges, including distinct pharmacokinetics, complex dosing, and toxicity. …”
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Comprehensive mitochondrial genomics of Fasciola gigantica from Sudan: insights into genetic diversity, evolutionary dynamics, and host adaptation by Bashir Salim, Nouh S. Mohamed, Kamal Ibrahim, Saeed Alasmari, Elisha Chatanga, Elisha Chatanga, Yuma Ohari, Nariaki Nonaka, Mohammad A. Alsaad, Faisal Almathen, Ryo Nakao, Ryo Nakao, Ryo Nakao

“…This work enhances understanding of F. gigantica’s genetic landscape and supports the development of more targeted molecular surveillance and control strategies for fascioliasis in endemic regions.…”
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A scenario-based analysis of wetlands as nature-based solutions for flood risk mitigation using the TELEMAC-2D model by Kirk B. Enu, Fabian Merk, Hao Su, Manuel Rauch, Aude Zingraff-Hamed, Karl Broich, Kristian Förster, Stephan Pauleit, Markus Disse

“…Results show that wetland cover declined (59 %) while built-up areas expanded (134 %), leading to reduced cumulative discharge and more intense, shorter-duration floods. The combined scenario (floodplain restoration and wetland creation) achieved consistent peak flow reductions (16–19 %) in prolonged storms, while the ambitious_restoration scenario (restoring the full floodplain network) performed best (24 %) in short-duration events. …”
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