SYMPTOMS OF INNER DISORDERS OF TEMPOROMANDIBULAR JOINTS BASED ON PATIENTS’ EXAMINATION OF TEMPOROMANDIBULAR DYSFUNCTION by R.V. Kulinchenko, A.V. Dvornyk, Yu. O. Kinash

“…Even if a pain was present, it mostly had a local (82,35±9,53% in pain sufferers) than irradiating character (17,65±9,53%). …”
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Toll interacting protein gene polymorphisms in patients with systemic sclerosis: association with interstitial lung disease, outcome, and survival by Niels Schröder, Jitka Andrä, Diana Knuth-Rehr, Silke Leja, Nicolas Hunzelmann, Pia Moinzadeh, Konrad Frank, Eda Börner, Francesco Bonella

“…From baseline.ResultsThe TOLLIP rs5743890 minor Allele (C) was more frequent in HC than in SSc patients (41% vs. 16%, p = 0.021). …”
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Evaluation of arthrodesis and cervical alignment in the surgical results of cervical discectomy using polymethylmetacrylate Avaliação da artrodese e do alinhamento cervical após di... by Marcelo Luis Mudo, Andrea Vieira Amantea, Andrei Fernandes Joaquim, Mirto Nelso Prandini, Sérgio Cavalheiro

“…CONCLUSIONS: Cervical alignment was more important than fusion to achieve good surgical results in CDD.…”
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Morbidity and health seeking behavior among children and adolescents (0–19 years): a household survey assessment in Northwestern Tanzania by Sophia Kagoye, Jim Todd, Milly Marston, Mark Urassa, Eveline T. Konje, Ties Boerma

“…Types of illnesses reported were similar across age groups, with Fever/Malaria accounting more than two-thirds, followed by respiratory tract illnesses. …”
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Long-term trajectories of apolipoprotein A1 and major adverse cardiovascular events and mortality in a community cohort by Yang Chen, Yun-Yu Chen, Kuo-Liong Chien, Yenn-Jiang Lin, Fang-Yi Chen, Yu-Cheng Hsieh, Gregory Y. H. Lip, Shih-Ann Chen

“…Dynamic monitoring of ApoAI may serve as a valuable tool for early risk stratification in high-risk populations, facilitating more individualised interventions.…”
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Evaluation of psychotropic effects of a novel chromone-containing allylmorpholine derivative in BALB/c mice by M. M. Puchik, D. D. Shitc, Yu. I. Sysoev, N. M. Chernov, I. A. Titovich, S. V. Okovityi

“…The present study investigated the effects of 33a on anxiety behavior, cognitive functions, and grip strength of BALB/c mice after acute and chronic administration.Materials and methods. …”
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Tissue-engineered vascular patches: comparative characteristics and preclinical test results in a sheep model by L. V. Antonova, A. V. Mironov, A. R. Shabaev, V. N. Silnikov, E. O. Krivkina, V. G. Matveeva, E. A. Velikanova, E. A. Senokosova, M. Yu. Khanova, V. V. Sevostyanova, T. V. Glushkova, R. A. Mukhamadiyarov, L. S. Barbarash

“…PHBV/PCL/VEGF patches have better biocompatibility and are more suitable for vascular wall reconstruction than PHBV/PCL/RGD patches.…”
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Industrial heat island and carbon emissions: machine learning-based environmental impact assessment in Cilegon, Indonesia by Agus Suprijanto, Yumin Tan, Muhammad Kamran Lodhi, Rodolfo Domingo Moreno Santillan, Isiaka Lukman Alage, Gonzalo Rodolfo Pena Zamalloa

“…The results reveal a staggering increase in carbon emissions, with Industrial Area 2 emitting 107 times more carbon than Industrial Area 1 due to coal-fired power plants. …”
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The effects of moderate-intensity continuous training and high-intensity interval training during a ketogenic diet on serum levels of irisin, PGC-1α and UCP1 in overweight and obes... by Behnam Behravan, Kazem Khodaei, Mohammadreza Zolfaghardidani

“…However, no significant between-group differences were observed in serum levels of PGC-1α, total cholesterol and low-density lipoprotein (p>0.05).Conclusion: Based on the findings of the present study, it seems that performing both types of continuous aerobic exercise with moderate intensity and intense interval along with the ketogenic diet is more effective than the ketogenic diet in terms of activating the browning pathways of adipose tissue and improving the blood lipid profile, in overweight and obese women. …”
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Comparison of telemedicine-assisted psychotherapy, exercise therapy, or a combination of both in patients with post-COVID-19 syndrome (TelPoCo): study protocol for a randomized con... by Sebastian Beyer, Mariel Nöhre, Isabell Pink, Sebastian Häckl, Nele Henrike Thomas, Frank Klawonn, Uwe Tegtbur, Martina de Zwaan, Sven Haufe

“…Abstract Background Post-COVID-19 syndrome (PCS) presents in a multitude of ways, with fatigue, physical constraints, and diminished quality of life being common symptoms. …”
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Single cell RNA sequencing reveals the reshaping effect of perfluorooctanoic acid on the intestinal microenvironment of mice by Ya Gao, Jiayun Guan, Rui Zhou, Zewei Li, Tianyang Chen, Kaican Yang, Rong Huang, Yue Huang, Siting Zheng, Zhenhua Huang, Xiaoxiang Rong

“…Histopathological analysis revealed that PFOA induced intestinal damage in both sexes, with a more severe impact observed in female mice. scRNA-seq analysis demonstrated that PFOA treatment triggered abnormal proliferation of intestinal epithelial cells, particularly the expansion of Adahigh enterocyte cells, suggesting their potential role in injury repair process. …”
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Considering Theory-Based Gamification in the Co-Design and Development of a Virtual Reality Cognitive Remediation Intervention for Depression (bWell-D): Mixed Methods Study by Mark Hewko, Vincent Gagnon Shaigetz, Michael S Smith, Elicia Kohlenberg, Pooria Ahmadi, Maria Elena Hernandez Hernandez, Catherine Proulx, Anne Cabral, Melanie Segado, Trisha Chakrabarty, Nusrat Choudhury

“…ConclusionsIn this paper, we present a process for the application of gamification that includes characterizing what was applied in a standardized way and identifying the underlying mechanisms that are targeted. …”
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FeNO as a biomarker of interstitial and fibrotic pulmonary sequelae in patients admitted for severe SARS-CoV-2 pneumonia by Diego Ferrer-Pargada, Carlos A. Amado, Beatriz Abascal-Bolado, Sandra Tello Mena, Pilar Alonso Lecue, Carlos Armiñanzas, Francisco Arnaiz de las Revillas, Miguel Santibáñez, Juan Agüero, Víctor Fernández Lobo, J. Gonzalo Ocejo-Vinyals, José Manuel Cifrian

“…The joint predictive ability of the overall model with the 6 more predictive variables was higher than 0.8: AUC (Use of systemic corticosteroids + peak C-reactive Protein at admission + Age + Endotracheal intubation + Diffusing Capacity for CO (DLCO) + FeNO as quantitative continuous) = 0.81; 95%CI (0.77–0.86). …”
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O modelo SASIS: validação da simulação da irrigação por sulco The SASIS model: validation of furrow irrigation simulation by Roberto V. Pordeus, Carlos A. V. de Azevedo, José Dantas Neto, Vera L. A. de Lima, Márcia R. de Q. A. Azevedo, José de A. de Matos

“…For most field data studied, the simulations of the advance phase by SASIS model presented discrepancies in the advance time at the end of the area, being inferior to the ones given by SIRMOD model, in relation to field measurements. …”
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Harnessing Actinobacteria secondary metabolites for tuberculosis drug discovery: Historical trends, current status and future outlooks by Luana Layse Câmara de Almeida, Sayoane Pessoa Fernandes, Genil Dantas de Oliveira, Marcelly da Silveira Silva, Thalisson Amorim de Souza, Valnês S. Rodrigues-Junior, Samuel Paulo Cibulski

“…Furthermore, hundreds of antimycobacterial metabolites have been isolated from Actinomycetota and can serve as effective drugs or useful agents for the discovery of new lead compounds to combat TB. The present review covers more than 171 isolated substances as potential antimycobacterial agents discovered between the years 1972 to 2024. …”
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Characterization of Chilean patients with sporadic colorectal cancer according to the three main carcinogenic pathways: Microsatellite instability, CpG island methylator phenotype... by Ana María Wielandt, Claudia Hurtado, Mauricio Moreno C, Cynthia Villarroel, Magdalena Castro, Marlene Estay, Daniela Simian, Maripaz Martinez, Maria Teresa Vial, Udo Kronberg, Francisco López-Köstner

“…Group 3: [MSI/CIN/CIMP]-low/negative tumors (30%) are left-sided, and 39% have KRAS mutations; Group 4: CIMP-high tumors (15%) were more frequent in men and left side colon, with 27% KRAS and 7% presented BRAF mutations. …”
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Correlations of oral behaviors, pain, and psychological distress among patients with temporomandibular disorders: clinical investigation of axial II evaluation by Yan Yu, Yan Yu, Lili Wang, Lili Wang, Chunxia Chen, Chunxia Chen, Mengmeng Wang, Mengmeng Wang, Shuai Nie, Shuai Nie, Lin Fu, Lin Fu

“…Within the TMD group, participants diagnosed with MPDS were found to have more psychological symptoms than those diagnosed with internal derangement and osteoarthritis. …”
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Heparin anticoagulation versus regional citrate anticoagulation for membrane therapeutic plasma exchange in patients with increased bleeding risk by Jing Jiao, Yan Yu, Suijiao Wei, Xiujuan Tian, Xiaoxia Yang, Shidong Feng, Yajuan Li, Shiren Sun, Peng Zhang, Ming Bai

“…However, for patients with increased bleeding risk, there were controversial opinions on the use of HA versus regional citrate anticoagulation (RCA) for mTPE. Our present study aimed to evaluate the efficacy and safety of HA vs. …”
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Clinical and laboratory characteristics of measles in children in St. Petersburg during a rise in incidence 2023–2024 by N. S. Tian, I. V. Babachenko, Yu. V. Nesterova, K. V. Zhdanov

“…Objective: to present the clinical and laboratory characteristics of measles in hospitalized children during the period of rising incidence in 2023-2024 in St. …”
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Medical on-call handbook for foundation doctors: a quality improvement project at Barts Health NHS Trust, London, UK by Carola Maria Bigogno, Francesca Bladt, Amy Edwards, Priyanka Sivakumaran, Lamin King

“…Conclusion: This quality improvement project demonstrated that a structured on-call handbook can significantly support and enhance FY1 doctors' confidence in managing emergencies, directly contributing to improved patient care and safety.5 Given its success, future developments will focus on creating a mobile app for easy accessibility, tailoring handbooks to specific hospital sites within the trust (Royal London Hospital, St Bartholomew’s, Newham University Hospital and Whipps Cross Hospital), and supplementing learning with a YouTube teaching series for more complex topics. These findings support the wider recommendations by the General Medical Council regarding the importance of structured educational interventions to support newly qualified doctors.3…”
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