Innovative gene delivery systems for retinal disease therapy by Hongguang Wu, Ling Dong, Shibo Jin, Yongwang Zhao, Lili Zhu

“…By systematically outlining these factors, our goal is to guide the selection of the optimal delivery tool for a specific retinal disease, which will enhance treatment efficacy and improve patient outcomes while paving the way for more effective and targeted therapeutic interventions.…”
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Unmasking the Fake: Machine Learning Approach for Deepfake Voice Detection by Muhammad Usama Tanveer Gujjar, Kashif Munir, Madiha Amjad, Atiq Ur Rehman, Amine Bermak

“…These MFCC features are then enhanced through a transformation process that employs a Gaussian Naive Bayes (GNB) model in conjunction with Non-Negative Factorization, creating a more discriminative feature set for subsequent analysis. …”
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A collaborative immunohistochemical study of Drp1 and cortactin in the epithelial dysplasia and oral squamous cell carcinoma by Marina Nader, Samar Soliman, Shaimaa M. Yussif, Azza Abbas El-Sissi

“…Abstract Objectives Oral squamous cell carcinoma (OSCC) accounts for more than 90% of oral malignancies. The poorly understood molecular and cellular mechanisms underlying the pathogenesis of OSCC remain a subject of paramount importance. …”
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Self-Care Practice and Associated Factors among Hypertensive Patients in Ethiopia: A Systematic Review and Meta-Analysis by Adam Wondmieneh, Getnet Gedefaw, Addisu Getie, Asmamaw Demis

“…Conclusion. In this study, more than half of hypertensive patients had poor hypertensive self-care practice in Ethiopia. …”
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Neutrino oscillation tomography of the Earth with the Hyper-Kamiokande detector by C. Jesús-Valls, S. T. Petcov, J. Xia

“…Considering the case of normal ordering (NO) of neutrino masses, we present results which illustrate the dependence of sensitivity to the core, lower and upper mantle average densities on the energy and zenith angle resolutions and on the value of $$\theta _{23}$$ θ 23 . …”
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Synthesis, physico-chemical studies and biological evaluation of new metal complexes with some pyrazolone derivatives by Ahmed M. Ramadan, Asma A. Alshehri, Samir Bondock

“…A series of N-substituted-4-thiocarbamoyl-5-pyrazolone derivatives (HL1-HL4) is presented as chelating agents for complexation with Fe(III), Ni(II) and Cu(II) metal ions. …”
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Modernization of operating chicory factories using continuous pulsating extractors by D. P. Iovlev, M. I. Farakhov, R. R. Akberov, I. R. Stekolshchikov, A. V. Akhmerov

“…A lower extraction temperature (up to 85°C) combined with a shorter extraction time (up to 1 hour) may help retain more inulin and other nutrients as compared to conventional methods. …”
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Pattern of depression among patients in a Nigerian family practice population by Muhammed O. Afolabi, Emmanuel A. Abioye-Kuteyi, Femi O. Fatoye, Ibrahim S. Bello, Abiodun O. Adewuya

“…Substance use was also significantly more common among depressed subjects than the non-depressed group. …”
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Wheat Protein Aggregation and Disaggregation Behaviors and Their Effects on Dough Rheological Properties and Noodle Qualities by Xiangke YU, Yuanxiao LIU, Jianli WANG, Shaoying LI, Xiaoning WANG, Tingjing ZHANG, Erqi GUAN

“…Enhanced aggregation behavior of wheat proteins leads to the formation of a more compact gluten network, which imparts the resultant dough with higher elasticity, water-holding capacity, and cohesiveness. …”
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Effect of concomitant use of hypertonic saline injection with anal cerclage for treatment of idiopathic partial rectal prolapse in children: a double hit therapy by Belal elezaby, Ahmed Arafat, wesam mahmoud, Sherif Kaddah, Mostafa Gad

“…Treatment starts usually by conservative management, but if it fails, physicians search for more effective methods for treatment such as sclerotherapy or surgical intervention. 15% hypertonic saline is one of the safe, cost effective and technically available sclerosants that could be injected, but it has a relatively high recurrence rate. …”
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Evaluation of Wear Resistance of a Modified Radial Bearing Design Taking into Account Compressibility and Viscosity of the Lubricant by E. A. Bolgova, M. A. Mukutadze, V. M. Prikhodko, I. A. Kolobov

“…The new model predicted the bearing capacity of the part by 8–10% more accurately, and the coefficient of friction — by 7–9%. …”
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Instrument-supported gait analysis characterizes gait domain changes in patients with suspected normal pressure hydrocephalus by Carolin Semmler, Veronika Wunderle, Taylan D. Kuzu, Oezguer A. Onur, Christian Grefkes, Michael T. Barbe, Gereon R. Fink, Peter H. Weiss

“…Notably, instrument-supported gait analysis validated this criterion by providing a more comprehensive characterization of gait disturbances compared to the 10 m walk test. …”
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Computed Tomographic Features of Bezoars and Other Gastrointestinal Foreign Bodies in Dogs and Cats: A Comparative Analysis by Jongwon Koo, Kidong Eom, Jaehwan Kim, Jeongyun Jeong, Hongji Yoon, Minsu Lee, Jinsoo Park, Jongmun Cho

“…This study presents a comparative analysis of the computed tomographic (CT), radiographic, and ultrasonographic (US) characteristics of gastrointestinal foreign bodies, including bezoars, in dogs and cats, and evaluates their association with complications and clinical outcomes. …”
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Monitoring water crisis from space across a Mediterranean region by Wassim Mohamed Baba, Abdelghani Chehbouni, Youness Ouassanouan, Simon Gascoin, Marc Paganini, Giuseppe Ottavianelli, Zoltan Szantoi

“…Abstract Water scarcity, driven by climate change and increased drying trends in the Mediterranean region, presents severe water availability and agricultural production shortages, particularly in North Africa. …”
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Critical Role of p38α MAPK Subclass in the Development of Pain Hypersensitivity After Hind Paw Incision by Ishikawa D, Yamakita S, Oh-Hashi K, Amaya F

“…Daiki Ishikawa,1 Shunsuke Yamakita,1 Kentaro Oh-Hashi,2– 4 Fumimasa Amaya1 1Department of Anesthesiology, Kyoto Prefectural University of Medicine, Kyoto, Japan; 2United Graduate School of Drug Discovery and Medical Information Sciences, Gifu University, Gifu, Japan; 3Center for One Medicine Innovative Translational Research (COMIT), Gifu University, Gifu, 501-1193, Japan; 4Department of Chemistry and Biomolecular Science, Faculty of Engineering, Gifu University, Gifu, 501-1193, JapanCorrespondence: Fumimasa Amaya, Department of Anesthesiology, Kyoto Prefectural University of Medicine, Kajii-Cho 465, Kamigyo-Ku, Kyoto, 602-0841, Japan, Tel +81-75-251-5633, Email ama@koto.kpu-m.ac.jpBackground: Deeper understanding of the mechanisms of postoperative pain is critical for developing more effective pain management strategies. The present animal study explored the function of four p38 mitogen-activated protein kinase (MAPK) subclasses (α, β, γ, and δ) in dorsal root ganglion (DRG) in the development of post-incisional pain hypersensitivity.Methods: The amount of p38 MAPK subclass mRNA in the DRG of male Sprague-Dawley rats was quantified using real-time PCR. …”
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Epidemiological Study of Hepatitis B, C and HIV Cases among the Foreigners Visiting Sulaimani City from 2013 Through 2016 by Mohammed Omer Mohammed, Asan Baram Hasan, Fenk Bakir Maarouf

“…Hepatitis B, C and HIV infections present a great public health problem worldwide. More than 350 million of world's populations have chronic HBV infection and near 1 million people are dying due to this infection each year. …”
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Switching to Faricimab for Polypoidal Choroidal Vasculopathy with Real-World Outcomes in Refractory Cases – The FAR-PEARL Study Report 1 by Fong KC, Wong WJJ, Wong HS, Ling KP, Fong SN, Shunmugam M

“…PED resolved in 53% after the first dose, and in those needing repeat injections, the interval peaked after the fourth dose with no SRF, IRF, nor PED.Conclusion: The differential response to faricimab in PCV depends on disease type, with recurrent cases requiring fewer injections and recalcitrant cases requiring more intensive initial treatment; however, even recalcitrant eyes can achieve extended intervals after initial doses.Keywords: polypoidal choroidal vasculopathy, faricimab, refractory neovascular AMD, anti-VEGF resistance, visual and anatomical outcomes, real-world study…”
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Bibliometric analysis of scientific literature on the use of suppositories in the treatment of prostate cancer patients by I. V. Bushuieva, M. V. Parchenko, O. O. Maliuhina

“…Statistical data from various literary sources indicate that more than 130,000 people in Ukraine receive this diagnosis as a sentence every year. …”
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Comprehensive Assessment of the Characteristics of Pediatric Patients with Diabetic Ketoacidosis: 11 Years of Data from a Tertiary Center by Selin İnce Açıcı, Esra Deniz Papatya Çakır

“…Conclusion: This study presents a comprehensive dataset concerning pediatric patients with DKA, and identifies multiple factors associated with DKA and its severity.…”
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Antimicrobial Treatment of Infective Endocarditis, Caused by <i>Enterococcus Faecalis by E. V. Shikh, T. E. Morozova, V. N. Drozdov, N. B. Lazareva, D. A. Shatsky, T. B. Andrushchyshina, M. V. Lukina, O. A. Vartanova

“…The incidence of IE morbidity is recorded in all countries of the world and in the Russian Federation more than 40 people per 1 million population get sick. …”
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