Utilization and dose optimization of beta-blockers in chronic heart failure therapy: a mixed-methods study by Sisay Sitotaw Anberbr, Tilaye Arega Moges, Abebech Tewabe Gelaye, Aragaw Dagnew Lakew, Samuel Berihun Dagnew, Gebremariam Wulie Geremew, Getachew Yitayew Tarekegn, Fisseha Nigussie Dagnew

“…Data were collected through structured questionnaires capturing socio-demographic details, clinical characteristics, and medication usage. Quantitative analysis was performed using SPSS version 27.0, applying binary logistic regression to identify factors associated with BB utilization and optimal dosing. …”
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Clinical characteristics and short-term outcomes of migraine with patent foramen ovale: a comparative study by Yongfei Sun, Nanqu Huang, Fei Feng, Yiman Xie, Tao Xu, Yuekui Sun, Yong Luo, Jian Zhan

“…Abstract Objective To analyze the clinical features and prognosis of migraine with PFO and explore their short-term prognostic factors. …”
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Prognostic Value of Spontaneous Potential in Left Atrial Posterior Wall Isolation and Radiofrequency Ablation for Non-Paroxysmal Atrial Fibrillation by Chen ZY, Zhong YH, Gong KZ, Chen XH, Xu Z, Zhang FL

“…Multivariate logistic regression analysis indicated that the duration of AF and the presence of left atrial posterior wall SP were independent risk factors for post-ablation recurrence in patients with NPAF.Conclusion: The presence of SP post-left atrial posterior wall isolation suggests a better long-term outcome in patients with NPAF following PVI+BOX catheter ablation.Keywords: left atrial posterior wall, non-paroxysmal atrial fibrillation, pulmonary vein isolation, radiofrequency ablation, spontaneous potential…”
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Outcomes of Pediatric Cardiopulmonary Resuscitation: A Retrospective Cross-Sectional Study from a Single Center by Saqan RS, Raffee LA, Zaitoun KJ, Zaitoun G, Tahtamoni SO, Alawneh KZ, Alawneh RK, Yasawy MA, AlAzab R

“…The Mann–Whitney U-test, Chi-Square test, and Fisher’s exact tests were used for analysis. Survival-associated factors were analyzed using univariate and multivariate logistic regression, and p < 0.05 was considered significant.Results: Patients were separated into a less than one year age group and a greater than one year age group, with similar gender distributions. …”
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Plasma-based transcriptomic non-coding signature for predicting relapse in pediatric acute lymphoblastic leukemia by Yaping Wang, Xiaopeng Ma, Huimin Li, Ji'ou Zhao, Meiyun Kang, Liucheng Rong, Yao Xue, Jiali Wang, Junwei Tang, Yongjun Fang

“…Logistic regression analysis revealed the superior predictive ability of the combined non-coding RNA panel compared to individual groups. …”
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Role of Artificial Intelligence and Deep Learning in Easier Skin Cancer Detection through Antioxidants Present in Food by Sreevidya R. C., Jalaja G, Sajitha N, D. Lakshmi Padmaja, S. Nagaprasad, Kumud Pant, Yekula Prasanna Kumar

“…After that, a linear regression analysis was carried out to obtain t and p values. …”
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Is It Enough to Stop Distal Fusion at L3 in Mild to Moderate Lenke 5C Adolescent Idiopathic Scoliosis Patients? by Chenkai Li, Xiaohan Ye, Haoran Zhang, Yang Yang, You Du, Yiwei Zhao, Shengru Wang, Jianguo Zhang

“…Demographics, radiological parameters, postoperative complications, and clinical outcomes were recorded. Univariate analysis and multivariate logistic analysis were used to identify the risk factors for postoperative complications in patients with L3 as the LIV. …”
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Association of Nutritional Intake with Physical Activity and Handgrip Strength in Individuals with Airflow Limitation by I Re Heo, Tae Hoon Kim, Jong Hwan Jeong, Manbong Heo, Sun Mi Ju, Jung-Wan Yoo, Seung Jun Lee, Yu Ji Cho, Yi Yeong Jeong, Jong Deog Lee, Ho Cheol Kim

“…However, in the multivariate logistic regression analysis, no significant associations were observed between nutritional intake and active aerobic PA or HGS. …”
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Single-cell sequencing and spatial transcriptomics reveal the evolution of glucose metabolism in hepatocellular carcinoma and identify G6PD as a potential therapeutic target by Deyang Xi, Deyang Xi, Yinshuang Yang, Jiayi Guo, Jiayi Guo, Mengjiao Wang, Mengjiao Wang, Xuebing Yan, Chunyang Li

“…High-throughput sequencing and experimental validation further suggested that G6PD-mediated regulation of HCC cell proliferation, migration, and invasion is likely associated with glutathione metabolism and ROS production. Finally, Cox regression analysis cofirmed G6PD as an independent prognostic factor for overall survival in HCC patients.ConclusionOur study provides novel insights into the changes in glucose metabolism in HCC from both temporal and spatial perspectives. …”
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A Survey-Based Study of Medication Safety Competence and Its Relationship with Safe Nursing Care among Nurses by Maryam Aghabarary, Fariba Katebi, Mostafa Bijani

“…To predict safe nursing care based on medication safety competency, multiple linear regression analysis was performed using the simultaneously (Enter) method. …”
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Expression of CSTF2 in oral squamous cell carcinoma and its relationship with immune infiltration and poor prognosis by Zumulaiti Aierken, Muertiza Muhetaer, Zhang Lei, Ainiwaerjiang Abudourousuli, Ainiwaerjiang Abudourousuli

“…The relationship between the infiltration of various immune cells and CSTF2 expression levels was assessed using single-sample gene set enrichment analysis (ssGSEA). Ultimately, the prognostic significance of CSTF2 was evaluated through Kaplan–Meier survival analysis, in conjunction with univariate and multivariate Cox regression analyses, as well as receiver operating characteristic (ROC) curves.ResultsHigh CSTF2 expression was observed in OSCC and associated with unfavorable clinicopathological variables, including histological grade and lymphnode neck dissection. …”
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Pulse pressure after thrombectomy predicts functional outcomes and mortality in acute ischemic stroke with large artery occlusion by Shandong Jiang, Zhongju Tan, Jianru Li, Peizheng Guo, Yuan Yuan, Jun Yu, Liang Xu, Xu Li, Xianyi Chen, Bing Fang, Lingling Yu, Jing Xu, Cong Qian, Chaohui Jing, Yunmei Yang

“…In this study, we systematically analyzed 12 post-procedure BP parameters from 826 acute ischemic stroke patients within 24 h after EVT; 587 cases were included in the final analysis. …”
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Healthy dietary patterns, biological aging, and kidney stones: evidence from NHANES 2007–2018 by Chengcheng Wei, Qian Yang, Qian Yang, Jingke He, Yu Luo, Kun Han, Junkun Li, Shuai Su, Shuai Su, Jindong Zhang, Hongxing Wang, Hongxing Wang, Delin Wang

“…Machine learning with Shapley Additive Explanations (SHAP) was used to determine the relative importance of dietary factors. Sensitivity analysis was conducted to validate the stability of the results.ResultsA higher healthy dietary score was significantly associated with a reduced risk of kidney stone prevalence, as indicated by the Alternative Healthy Eating Index (AHEI) (OR = 0.76, 95% CI 0.69–0.84), the Dietary Approaches to Stop Hypertension Index (DASHI) (OR = 0.67, 95% CI 0.58–0.77), the Healthy Eating Index 2020 (HEI-2020) (OR = 0.80, 95% CI 0.72–0.89), and the Mediterranean Diet Index (MEDI) (OR = 0.81, 95% CI 0.73–0.89). …”
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INBRX-106: a hexavalent OX40 agonist that drives superior antitumor responses via optimized receptor clustering by William L Redmond, Yoshinobu Koguchi, Melissa J Kasiewicz, Annah S Rolig, Nisha Holay, Bryan Becklund, Anya Polovina, Sae Jeong Ahn, Brendan P Eckelman, Rashi Yadav, Thi Staebler, Noah D Simons, Yaiza Diaz de Durana

“…Costimulatory agonists like OX40 (CD134), a tumor necrosis factor receptor family member critical for T-cell survival and differentiation, have shown preclinical promise but limited clinical success due to suboptimal receptor activation. …”
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Positive mental health literacy and job well-being among palliative care nurses: the mediating effect of job crafting by Haiyang Lin, Cunqing Deng, Zhuoxi Xie, Wenjie Zeng, Yumei Li, Yanping Hao

“…Analyses included hierarchical regression analysis, Pearson correlation analysis, and mediation analysis were also performed to analyze the data, using IBM SPSS25.0 and PROCESS V4.2. …”
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Impact of Tricuspid Regurgitation Severity on Accuracy of Echocardiographic Estimation of Systolic Pulmonary Artery Pressure in Patients With Pulmonary Arterial Hypertension by Jiawang Xiao, Jianming Wang, Shuai Huang, Jingsong Geng, Lili Meng, Zhongchao Wang, Qiguang Wang

“…A difference in sPAP of less than 10 mmHg between echocardiographic estimation by peak TR velocity and RHC measurement was defined as accurate, with a difference ≥10 mmHg considered inaccurate. The factors affecting the accuracy of echocardiographic sPAP estimation were analyzed by univariate and multivariate analysis. …”
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Effect of deterioration of swallowing functions on the frailty status in older adults: a longitudinal cohort study by En-Chih Weng, Yoko Hasegawa, Tasuku Yoshimoto, Ma. Therese Sta. Maria, Koutatsu Nagai, Naoko Sato, Kana Tokumoto, Kazuhiro Hori, Hiroshi Kusunoki, Hiromitsu Kishimoto, Ken Shinmura

“…In contrast, logistic regression analysis of frailty progression showed that impaired swallowing function was a significant explanatory variable (OR, 1.53; 95% CI: 1.04–2.21). …”
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Soluble galectin-4 in colorectal cancer is associated with tumor progression, but is not a predictor of the disease outcome by Elena Y. Yakunina, Olga V. Kovaleva, Ruslan A. Zukov, Alexey N. Gratchev, Sergey S. Salamatin, Sofya O. Kochkina, Zaman Z. Mammadli, Nikolay E. Kushlinskii

“…The galectin-4 levels were higher at advanced stages of the disease (p = 0.002) and in the presence of distant metastases (p 0.0001). Cox regression analysis showed that tumor size and distant metastases were independent prognostic factors (hazard ratio (HR) = 3.87; p = 0.0439; HR = 720.4; p = 0.0062, respectively) associated with decreased survival. …”
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Relationship Between Internet Use and Cognitive Function Among Middle-Aged and Older Chinese Adults: 5-Year Longitudinal Study by Bowen Chen, Chun Yang, Shanshan Ren, Penggao Li, Jin Zhao

“…We used a fixed effects model to assess the relationship between internet use and cognitive decline and further validated it using multiple linear regression analysis, generalized estimating equations, propensity score matching, inverse probability of treatment weighting, and overlap weighting. …”
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Electrocardiographic findings for predicting the left anterior descending artery chronic total occlusion in patients with inferior ST-segment elevation myocardial infarction by Xiaobin Zheng, Zhaofu Zhang, Bingqi Yao, Haiyan Wu

“…Multivariate logistic regression analysis indicated that QRS V4 (OR = 1.062, P = 0.003), ST V4↓- ST III↑ (OR = 1.641, P = 0.050), and Killip classification (OR = 2.115, P = 0.004) were all independent risk factors for LAD occlusion. …”
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