Differentiating Pulmonary Nodule Malignancy Using Exhaled Volatile Organic Compounds: A Prospective Observational Study by Guangyu Lu, Zhixia Su, Xiaoping Yu, Yuhang He, Taining Sha, Kai Yan, Hong Guo, Yujian Tao, Liting Liao, Yanyan Zhang, Guotao Lu, Weijuan Gong

“…Results A total of 267 participants were enrolled, including 210 with low‐risk and 57 with moderate‐risk pulmonary nodules. Univariate analysis identified 11 exhaled VOCs associated with nodule malignancy, alongside two lifestyle factors (smoke index and sites of tobacco smoke inhalation) and one clinical metric (nodule diameter) as independent predictors for moderate‐risk nodules. …”
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Characterization and Detection Strategy Exploration in Cryptogenic Hepatocellular Carcinoma: Insights From a Super‐Aged Region in Japan by Takaaki Sugihara, Takakazu Nagahara, Takuya Kihara, Suguru Ikeda, Yoshiki Hoshino, Yukako Matsuki, Takuki Sakaguchi, Hiroki Kurumi, Takumi Onoyama, Tomoaki Takata, Tomomitsu Matono, Hajime Isomoto

“…In the multivariate regression analysis, age and women emerged as independent factors associated with c‐HCC. …”
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The global impact of non-alcoholic fatty liver disease (including cirrhosis) in the elderly from 1990 to 2021 and future projections of disease burden. by Siying Huang, Weitao Hu, Taiyong Fang

“…This dataset includes incidence rates of NAFLD. The Joinpoint regression model was utilized to detect turning points in the epidemiological trends of NAFLD, and decomposition analysis was performed to analyze the factors influencing these trends. …”
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Biomarkers reflecting disturbed gut barrier under treatment with TNF inhibitors in radiographic axial spondyloarthritis by Denis Poddubnyy, Hildrun Haibel, Fabian Proft, Mikhail Protopopov, Valeria Rios Rodriguez, Murat Torgutalp, Judith Rademacher, Laura Spiller, Christine Maria Hempel

“…We analysed the longitudinal association between biomarkers and disease activity, and the relationship between biomarkers and treatment response with regression analysis.Results 121 patients with r-axSpA were compared with 63 controls. …”
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Examining the relationship between oral health indicators, obesity, and Xerostomia in older adults by Raziyehsadat Rezvaninejad, Mahdie Zeinali, Amirreza Fatemi, Maryam Alsadat Hashemipour

“…Data were collected using a structured questionnaire consisting of five sections: (I) demographic information, (II) oral health (issues such as loose teeth, tooth loss, use of dentures/implants, bleeding gums - self based on reported questionnaires and dental examination), (III) general health, (IV) overweight and/or obesity ( based on BMI- Height and weight measurement by a final year dental student), and (V) xerostomia (self-reported questionnaires). Statistical analysis was performed using the SPSS 24 software, with methods including T-test, Kruskal-Wallis, ANOVA, Chi-Square test, Pearson correlation coefficient, and logistic regression. …”
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Elevated effluent lactate independently predicts the adverse outcomes of peritoneal dialysis associated peritonitis by Xiao Yu, Jingyuan Wang, Changna Liang, Zhao Li, Wanhong Lu, Jing Lv, Ying Ma

“…We used logistic regressions and receiver operating characteristic curve (ROC) analysis to assess factors linked to outcomes and the lactate level predictive accuracy for PDAP adverse outcomes, respectively. …”
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Association Between Preoperative Cognitive Performance and Postoperative Delirium in Older Patients: Results From a Multicenter, Prospective Cohort Study, and a Mendelian Randomiza... by Rao Sun, Shiyong Li, Changming Yang, Guiming Huang, Chunrong Tang, Wei Li, Zhongyuan Xia, Mingzhang Zuo, Ning Yang, Huiyu Luo, Kun Zhang, Huajun Li, Qingfeng Zeng, Chun Chen, Lan Wang, Rui Xia, Chuanbin Dong, Junmin He, Qiaoqiao Xu, Xinhua Li, Biyun Zhou, Shangkun Liu, Fang Luo, Zhiqiang Zhou, Ailin Luo

“…ABSTRACT This study evaluated the association between preoperative cognitive performance and postoperative delirium (POD) using a multicenter prospective cohort, and explored potential causality using Mendelian randomization (MR) analysis. We analyzed data from 2257 patients aged ≥ 75 years undergoing elective noncardiac and noncranial surgeries across 16 Chinese medical centers. …”
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Relationship between breastfeeding duration, lifestyle and obesity in children aged 3–16 years: a cross-sectional study by Yu Liu, Yiyao Gu, Jie Mu, Zhi Duan, Xixiang Wang, Xiuwen Ren, Lu Liu, Jingjing Xu, Chi Zhang, Shaobo Zhou, Ning Ma, Linhong Yuan, Ying Wang

“…Assigned and calculated the score of lifestyle habits and the total score of lifestyle habits and breastfeeding. Logistic regression was used to analyze the risk of obesity with breastfeeding and/or lifestyle habits scores, and ROC curves were applied to evaluate the accuracy of the models. …”
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Therapeutic effects of children with refractory epilepsy after vagus nerve stimulation in Taiwan by Sung-Tse Li, Nan-Chang Chiu, Kun-Long Hung, Che-Sheng Ho, Yung-Ting Kuo, Wen-Hsiang Wu, Chuan-Yu Wang, Yung-Ting Kuo, Huei-Shyong Wang, Kuang-Lin Lin, Po-Cheng Hung, Ying-Chao Chang, Pi-Lien Hung, Pi-Chuan Fan, Wang-Tso Lee, Rei-Cheng Yang, Fang-Jong Ko, Lung-Chang Lin, Po-Ching Chou, Jeng-Dau Tsai, Kun-Long Hung, Hui-Ju Chen, Kai-Ping Chang, Ting-Rong Hsu, Che-Sheng Ho, Nan-Chang Chiu, Shyi-Jou Chen, Hueng-Chuen Fan, Hsu-Tung Lee, Ein-Yiao Shen, Huang-Tsung Kuo, Ming-Yuh Chang, Tung-Ming Chang, Sung-Tse Li, Geng-Chang Yeh

“…This study aimed to use Taiwanese nationwide registry data to analyze the therapeutic effects of VNS in children with refractory epilepsy (RE) and try to explore predictive factors of VNS treatment effectiveness. …”
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Effects of otolaryngological diseases on sleep quality, anxiety, and depression: a multicenter observational study by Cheng-Lin Qi, Qin-Ying Wang, Mi Wang, Lin-Bin Cai, Meng-Qing Shen, Kan Liu, Jin-Long Zhu, Cong Wang, Qi-Bing Chen, Ting-Ting Wu, Shui-Hong Zhou, Jin-Hua Pan

“…Multivariable polynomial linear regression models explored the impact of different otolaryngological diseases on anxiety, depression and sleep quality, and mediation analysis explored the interaction mechanisms. …”
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The association of pesticide exposure on anthropometric parameters among under-five children in Magelang Regency, Central Java Province, Indonesia: a cross-sectional study by Sani Rachman Soleman, Fresti Oktanindi, Shofiati Ashfia, Emi Azmi Choironi, Muhammad Fathi Banna Al Faruqi, Desvialin Ulfa Talitha, Afifah Az Zahra, Syifa Nurul Asma

“…Introduction: As endocrine disruptor chemicals, pesticides pose hormone-associated diseases, such as growth and developmental pathologies, in children through IGF-1 modulators. This study aims to analyze pesticide exposure on anthropometry status in under-five children and related factors that contribute to them. …”
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The Influence of Pelvic Bone Dose-volume Parameters on Bone Marrow Suppression During Radiation Therapy in Patients With Stage I to III Rectal Cancer Based on Real-world Data by Botian Huang, MD, Jiansheng Lv, MM, Jianqi Xiong, MM, Fang Peng, MD, Liyang Zhuo, MM, Zhuangzhuang Yang, MM, Xiaowu Deng, MD, Yong Bao, PdD, MM, Shaoqing Niu, MD, PhD

“…The primary endpoint was grade ≥ 2 HT (HT2+), including leukopenia, neutropenia, anemia, thrombocytopenia, and total HTs. Logistic regression was employed to analyze the associations of HT2+ with dosimetric parameters and clinicopathologic characteristics. …”
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Correlation Between the Online Visiting Time and Frequency Increase in Telemedicine Services Offered by Health Care Providers Before, During, and After the COVID-19 Pandemic in Chi... by Weiyi Wang, Yuntian Chu, Fangfang Cui, Xiaobing Shi, Xu Zhang, Dongxu Sun, Jinming Shi, Jie Zhao

“…Chi-square tests were applied to compare general differences in the between-group telemedicine frequency. Regression models were performed to analyze correlations between the frequency change and the time spent in online versus in-person visits. …”
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Impact of Subjective and Objective Green Space Characteristics on Mental Health Benefits: An Explainable Machine Learning Approach by Ke LI, Yipei MAO, Yongjun LI

“…Specifically, perceived attractiveness is the most important contributing factor, followed by perceived greenness and perceived noise. …”
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Mediating roles of corneal biomechanical and topographic parameters in eye rubbing and keratoconus based on the Chinese keratoconus cohort study by Kaili Yang, Kaili Yang, Runqi Tu, Liyan Xu, Liyan Xu, Yuwei Gu, Qi Fan, Shanshan Yin, Yi Yuan, Anqi Chang, Yifan Wang, Chenchen Yin, Yonghao Zang, Chenjiu Pang, Daniela Oehring, Yibin Hao, Shengwei Ren, Shengwei Ren

“…The Spearman correlation and generalized linear regression models were used to analyze the associations between the time of eye rubbing, -SPA1, Kmax, and KC. …”
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Surgical complications of vagus nerve stimulation surgery: A 14-years single-center experience by Jouke van Schooten, Jacco Smeets, Sander MJ. van Kuijk, Sylvia Klinkenberg, Olaf E.M.G. Schijns, Jeske Nelissen, Louis G.L. Wagner, Rob P.W. Rouhl, Marian H.J.M. Majoie, Kim Rijkers

“…Univariable and multivariable logistic regression analysis were performed to analyze possible risk factors, in case of a small sample size, an independent-samples t-test and Fisher's exact test or Pearson's X2-test were used. …”
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Sedentary Behavior and Physical Activity Are Independent Predictors of Successful Aging in Middle-Aged and Older Adults by Shilpa Dogra, Liza Stathokostas

“…Methods. 9,478 older (M = 4,245; F = 5,233) and 10,060 middle-aged (M = 4.621; F = 5,439) adults from the Healthy Aging cycle of the Canadian Community Health Survey were analyzed. Multivariate logistic regressions were conducted with SA and its three components as outcomes while physical activity and sedentary behavior were entered as main exposures. …”
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A novel vasculogenic mimicry-related nomogram predicts prognosis in hepatocellular carcinoma by Yun Zhong, Yun Zhong, Yun Zhong, Yun Zhong, Fadian Ding, Fadian Ding, Fadian Ding, Fadian Ding, Han Zhang, Han Zhang, Han Zhang, Han Zhang, Denghan Zhang, Denghan Zhang, Denghan Zhang, Denghan Zhang, Xiang Zhang, Xiang Zhang, Xiang Zhang, Xiang Zhang, Shangeng Weng, Shangeng Weng, Shangeng Weng, Shangeng Weng

“…Biological process (BP), Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analysis, and gene set enrichment analysis (GSEA) were applied to analyze the biological function of the hub genes. …”
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Dynamics of HDL-Cholesterol Following a Post-Myocardial Infarction Cardiac Rehabilitation Program by Carlos Bertolín-Boronat, Héctor Merenciano-González, Víctor Marcos-Garcés, María Luz Martínez-Mas, Josefa Inés Climent Alberola, Nerea Pérez, Laura López-Bueno, María Concepción Esteban-Argente, María Valls Reig, Ana Arizón Benito, Alfonso Payá Rubio, César Ríos-Navarro, Elena de Dios, Jose Gavara, Juan Sanchis, Vicente Bodi

“…Changes in lipid profiles were evaluated, and predictors of failure to increase HDL-C levels were identified by binary logistic regression analysis. …”
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The effects of Tripterygium wilfordii Hook F on renal outcomes in type 2 diabetic kidney disease patients with severe proteinuria: a single-center cohort study by Yaqi Cheng, Yuhao Liu, Liling Lin, Danni Li, Liying Peng, Ke Zheng, Jianling Tao, Mingxi Li

“…Kaplan-Meier curves and Cox regression analyses were performed to analyze prognostic factors for renal outcomes.Results By the end of the follow-up, renal outcomes were observed in 23 and 11 patients in the non-TwHF and TwHF groups, respectively (p = 0.006). …”
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