Genetic influence of the brain imaging phenotypes, brain and cerebrospinal fluid metabolites and brain genes on migraine subtypes: a Mendelian randomization and multi-omics study by Ping-An Zhang, Jie-Lin Wang, Mei-Hua Dong, Xiang-Chun Huang, Nai-Jian Li, Run-Dong Qin, Jing Li

“…Mediation analysis revealed five significant mediation pathways were identified. …”
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HGF-rs12536657 and Ocular Biometric Parameters in Hyperopic Children, Emmetropic Adolescents, and Young Adults: A Multicenter Quantitative Trait Study by Jesús Barrio-Barrio, Elvira Bonet-Farriol, Marta Galdós, Susana Noval, Victoria Pueyo, Charles E. Breeze, Jose Luis Santos, Belén Alfonso-Bartolozzi, Sergio Recalde, Ana Patiño-García

“…Several HGF (hepatocyte growth factor) gene variants have been associated with ocular refractive errors and corneal pathology. …”
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Variations of Lipoprotein(a) Levels in the Metabolic Syndrome: A Report from the Maracaibo City Metabolic Syndrome Prevalence Study by Valmore Bermúdez, Joselyn Rojas, Juan Salazar, Luis Bello, Roberto Áñez, Alexandra Toledo, Maricarmen Chacín, Miguel Aguirre, Marjorie Villalobos, Mervin Chávez, María Sofía Martínez, Wheeler Torres, Yaquelin Torres, José Mejías, Edgardo Mengual, Liliana Rojas, Milagro Sánchez de Rosales, Ana Quevedo, Raquel Cano, Mayela Cabrera, Rafael París, Adonías Lubo, María Montiel, Climaco Cano

“…Results were expressed as Mean ± SD, determining differences through Student’s t-test and One-Way ANOVA test. Multiple logistic regression models were utilized for analyzing factors associated with elevated serum Lp(a) levels and MS. …”
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Top-tier ranking university bring worse perception of medical learning environment to students: a cross-sectional study across 12 universities by Runzhi Huang, Xinyue Yang, Yuntao Yao, Yan Gao, Shuyuan Xian, Wei Zhang, Dayuan Xu, Xinya Guo, Yang Chen, Yixu Li, Xirui Tong, Weijin Qian, Bingnan Lu, Min Lin, Meiqiong Gong, Xiaonan Wang, Yue Wang, Wenfang Chen, Chongyou Zhang, Erbin Du, Qing Lin, Zongqiang Huang, Huabin Yin, Jie Zhang, Yifan Liu, Xue Qu, Shizhao Ji

“…Through multivariate logistic regression analysis, we validated university category as an influencing factor (p < 0.001). …”
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Upregulation of TRPS1 promotes proliferation, migration, and invasion in ovarian clear cell carcinoma and correlates with poor patient prognosis by Jingfang Liu, Beier Wu, Shihan Wan, Yanlu Jin, Li Yang, Meijuan Wu, Jie Xing, Jiejie Zhang, Xin Chen, Aijun Yu

“…Statistical methods, including Chi-square tests, Kaplan-Meier survival analysis, and Cox regression, were employed to evaluate the correlation between TRPS1 expression and clinicopathological parameters. …”
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Trends and forecasts of the prevalence and mortality of Alzheimer’s disease and other dementias in China by Mingxuan Hou, Mingxuan Hou, Ling Yang

“…Risk factor analysis highlighted obesity (AAPC = 9.87%) as the leading contributor to AD mortality in China, surpassing global averages. …”
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Prevalence and clinical significance of HBeAg-positive chronic hepatitis B patients with and without anti-HBe antibody by Ruifei Xue, Jian Wang, Jie Zhan, Zhiyi Zhang, Suling Jiang, Jiacheng Liu, Li Wang, Xiaomin Yan, Shengxia Yin, Xin Tong, Weimao Ding, Jie Li, Yuxin Chen, Rui Huang, Chao Wu

“…A total of 840 treatment-naïve HBeAg-positive CHB patients from two medical centres were included. Cox regression analysis was used to analyze factors associated with HBeAg clearance and seroconversion. …”
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ASSOCIATION BETWEEN HEMOGLOBIN LEVEL AND BODY MASS INDEX IN THE FIRST TRIMESTER OF PREGNANCY WITH BIRTHWEIGHT IN TEMBALANG by Saniya Millatina, Nurul Setiyorini, Vannya Dewi Puspitasari, Ani Margawati

“…Low nutrional status, namely low body weight and anemia were the risk factor of LBW incident. Objective: To analyze the association features between hemoglobin levels and body mass index in the first trimester of pregnancy with LBW in Tembalang. …”
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Evaluación del rol del equipo de coordinación de nefrología en la consulta externa específica de acceso vascular. ¿Qué podemos aportar de nuevo? by Néstor Fontseré, Gaspar Mestres, Xavi Yugueros, Daniel Gil, Carla Blanco, Valentín Lozano, Lidia María Rodas, Arantxa Gelabert, Paula Escarcena, Rosa Ramos, Francisco Maduell

“…We compared the differences in the preoperative variables between the groups in which the assessments between the two teams were coincident and non-coincident, and the primary (PP) and secondary (PS) patencies during the follow-up period (Kapplan-Meier curves and Log-rank test, and Cox regression analysis). Significant P≤.05. Results: A total of 605 VA creations or repairs were analyzed: 74 ligations (12.2%), 207 distal arterio-venous fistulaes (AVF) (34.3%), 237 proximal AVF (39.2%), 35 repairs (5.7%), 41 grafts (6.7%) and 11 others (1.9%). …”
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Evaluation the role of the nephrology team in the specific vascular access outpatient clinic. What can we contribute new? by Néstor Fontseré, Gaspar Mestres, Xavi Yugueros, Daniel Gil, Carla Blanco, Valentín Lozano, Lida María Rodas, Arantxa Gelabert, Paula Escarcena, Rosa Ramos, Francisco Maduell

“…We compared the differences in the preoperative variables between the groups in which the assessments between the two teams were coincident and non-coincident, and the primary (PP) and secondary (PS) patencies during the follow-up period (Kapplan-Meier curves and Log-rank test, and Cox regression analysis). Significant P ≤ 0.05. Results: A total of 605 VA creations or repairs were analyzed: 74 ligations (12.2%), 207 distal arterio-venous fistulaes (AVF) (34.3%), 237 proximal AVF (39.2%), 35 repairs (5.7%), 41 grafts (6.7%) and 11 others (1.9%). …”
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Knowledge, attitude, and acceptance of COVID-19 vaccine in pregnant women by Arissara Kuptarak, Vorapong Phupong

“…Univariate and multivariate logistic regression analyses were performed to analyze the data. …”
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Relationship between maternal gingival bleeding during pregnancy and neurodevelopmental delay in their one-year-old children by Xiayu ZHANG, Lianman LEI, Lianjie DOU, Min YU, Min ZHU, Chao ZHANG, Jiahu HAO

“…Multivariable unconditional logistic regression models were used to analyze the relationship between maternal gingival bleeding symptoms during pregnancy and neurodevelopmental delay in their one-year-old children. …”
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Donor-derived cell-free DNA and miRNA monitoring for the early prediction and diagnosis of liver allograft rejection and patient outcomes by Judit Julian, Olga Millán, Olga Millán, Esther Titos, Pablo Ruiz, Yiliam Fundora, Alba Díaz, Alba Díaz, Jordi Colmenero, Jordi Colmenero, Constantino Fondevila, Constantino Fondevila, Joan Anton Puig-Butillé, Mercè Brunet, Mercè Brunet

“…The diagnostic performance of the levels of dd-cfDNA and signature miRNAs was assessed through receiver operating characteristic (ROC) curve analysis and logistic regression models.Resultsdd-cfDNA levels were significantly elevated during acute rejection (AR) episodes, with a median 3.9-fold increase over those in stable patients. …”
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Characteristics of adherent and non-adherent patients with hypertension in a Norwegian cross-sectional study by Eirik Olsen, Lene V. Halvorsen, Stine Rognstad, Arleen Aune, Karl Marius Brobak, Ola Undrum Bergland, Vibeke N. Kjær, Knut Liestøl, Marit D. Solbu, Rune Mo, Eva Gerdts, Morten Rostrup, Sverre E. Kjeldsen, Aud Høieggen, Mimi S. Opdal, Anne Cecilie K. Larstorp, Camilla L. Søraas

“…We found the non-adherent patients to be younger (56.9 vs. 63.7 years, p < 0.001), with higher systolic and diastolic office BP (150.4/91.4 vs. 143.2/82.0 mmHg, p < 0.01) and less likely to be of European ethnicity (82.9% vs. 95.8%, p < 0.001). Factors associated with non-adherence in logistic regression analysis were age, number of antihypertensive pills, non-European ethnicity, and inversely the use of angiotensin receptor blockers. …”
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Effects of the pretransplant obesity on kidney transplant outcomes in Korea: a nationwide cohort study by Eun-Young Cho, You Hyun Jeon, Kyu Ha Huh, Seun Deuk Hwang, Sangil Min, Jaeseok Yang, Myoung Soo Kim, Yu Jin Seo, Jeong-Hoon Lim, Hee-Yeon Jung, Ji-Young Choi, Sun-Hee Park, Yong-Lim Kim, Jang-Hee Cho, Chan-Duck Kim, The Korean Organ Transplantation Registry Study Group

“…Cox proportional hazard regression analysis was employed to assess associations between BMI and posttransplant outcomes. …”
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The influence of buyer knowledge and economic level on sports product purchasing decisions by Ilham Ilham, Raihan Alfarobi Raihan, Bekir Erhan Orhan, Vlad Adrian Geantă Geantă

“…Hypotheses were tested through linear regression analysis with a significance threshold of p < 0.05. …”
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The Effect of Work Motivation and Organizational Culture on Employee Performance at PT. Matahari Department Store Grage Mall Cirebon City by Dea Marina Fenawati, Dwi Septiyani, Muhammad Alwi

“…By using a quantitative approach with a survey method, where data is collected through questionnaires distributed to respondents who are employees of the company. Data analysis was carried out using multiple linear regression methods to test the relationship between independent variables and dependent variables. …”
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Presence of coronary artery disease in adults with newly detected diabetes mellitus by Cheng-Chien Lai, Betty Chia-Chen Chang, Lee-Ching Hwang

“…Using multiple logistic regression analysis, new detection of diabetes mellitus was identified as an independent risk factor for significant coronary artery disease (odds ratio: 2.153, 95% confidence interval: 1.112–4.166). …”
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Significance of serum IgA/C3 ratio in the diagnosis and prognosis of IgA nephropathy by XIE Wei-ji, HONG Gui-tian, XUE Qian, LIN Zhi-jun, XIE Yi, XU Xiao-chang, ZHANG Yi-min

“…The differences of the serum IgA/C3 ratio between IgAN and other related glomerular diseases and the IgA/C3 changes before and after treatment were analyzed. Results(1)The serum IgA/C3 ratio for IgAN,primary non-IgANand LN were 3.0±1.3, 1.9±0.8 and 6.9±4.9,respectively, with statistical significance of the differences of IgAN vs primary non-IgAN(P<0.01)and vs LN(P<0.01).(2) The serum IgA/C3 ratios for the primary non-IgAN subgroups minimal change nephritis(MCD), membranous nephropathy(MN) and focal segmental glomerulosclerosis(FSGS) were 1.9±0.8,1.9 ± 0.8 and 2.1±0.5,respectively.There was statistically significant difference of IgAN vs MCD(P<0.01), vs MN(P<0.01) and vs FSGS IgAN(P<0.01).(3)By multivariate regression analysis, IgA/C3 ratio(OR=2.509,95%CI 1.196～5.262,P=0.015) could be regard as an important risk factor for patients to suffer IgA Ninthe primary glomerular disease group.(4) The serum IgA/C3 ratio sexhibited statistically significant difference of IgAN + dialysis vs non-IgAN +dialysis[(3.7±1.8 vs(1.8±0.6),P=0.011] and vs non-IgAN + non-dialysis[(3.7±1.8) vs(1.9±0.8),P=0.005].(5) In the ROC curve diagnosis for IgAN and primary non-IgAN diseases, the cut point of the serum IgA/C3 ratio was equal to or greater than 2.106 or greater with the area under the curve of 0.775(P<0.01), which assisted to distinguish IgAN with other primary glomerular disease.(6) Among 43 IgAN patients who were followed up, 37 ones acquired remission in proteinuria 24 hours after treatment.The serum IgA/C3 ratios before treatment(with proteinuria remission) and after treatment(without proteinuria remission) were(3.1±1.1) vs(2.3±0.9),with difference of statistical significance(t=3.506,P=0.001).Conclusions Theserum IgA/C3 ratio is of significance in the diagnosis and differential diagnosis of IgAN among primary glomerular diseases, and the decrease of the ratio maybe a positive factor for prognosis of IgAN.…”
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[Artículo traducido] El índice de comorbilidad de Charlson ajustado por la edad en las fracturas acetabulares de los pacientes ancianos by J.M. Bogallo, C. Castillejo, A. Ramirez, J.R. Cano, F. Rivas-Ruiz, E. Guerado

“…Abstract: Objective: This study aimed to analyze factors of comorbidity in older patients with acetabular fracture to know the role of disease in the treatment of this population. …”
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