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3001
A Genome-wide study on the genetic and causal effects of smoking in neurodegeneration
Published 2025-07-01“…Genetic correlations were evaluated using linkage disequilibrium score regression (LDSC), and causal relationships were assessed through multiple Mendelian randomization methods including inverse-variance weighted (IVW), MR-Egger regression, weighted median (WME), weighted mode (WM), and simple mode (SM). sensitivity analyses were performed to examine heterogeneity, horizontal pleiotropy, and conduct leave-one-out analysis. …”
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3002
The association between triglyceride-glucose index, atherogenic index of plasma, systemic immune-inflammation index, and mortality in patients with acute coronary syndrome: the dir...
Published 2025-07-01“…Additionally, multivariable logistic regression, RCS models, and mediation analysis were used to assess associations and pathways.ResultsElevated TyG index linearly increased mortality risk in ACS patients (Odds Ratio (OR) = 1.64, 95% Confidence Interval (CI):1.07–2.52) and AMI subgroups (OR = 1.56, 95% CI:1.00–2.42), with minimal SII mediation (ACS:3.97%; AMI: non-significant).The AIP index directly increased mortality risk (ACS: Beta coefficient (β) = 0.076; AMI: β = 0.091, p < 0.001), partially offset by SII's negative mediation (ACS:−6.6%; AMI:−7.8%). …”
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3003
Serum LEAP2 Levels Across the Spectrum of Metabolic Dysfunction-Associated Fatty Liver Disease: A Potential Noninvasive Biomarker for Severity Stratification
Published 2025-07-01“…Multivariate logistic regression identified serum LEAP2 as an independent factor associated with MAFLD presence (OR=1.14, 95% CI 1.03– 1.26; P=0.014), alongside BMI and ALT, while HDL was protective. …”
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3004
Spatio-temporal distribution of zooplankton inhabiting Nile River in Qena Governorate, Egypt using Geomatics approach
Published 2025-03-01“…It also assesses and analyze the relationship between environmental variables and zooplankton distribution focusing on four major groups: Cladocera, Copepoda, Rotifera, and Ostracoda. …”
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3005
Low ALT levels and a new diagnosis of congestive heart failure following COVID-19 infection
Published 2025-08-01“…It is vital to identify factors associated with CHF post COVID so as to improve outcomes. …”
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3006
Dual trajectory of insomnia and depressive symptoms in women from early pregnancy to 6 months postpartum: a prospective cohort study
Published 2025-05-01“…Group-based trajectory modelling and binary logistic regression modelling were used to analyze the data (n = 436). …”
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3007
Aging in smog: How air pollution and inequality shape relocation decisions among China's older adult
Published 2025-06-01“…Regression analysis was conducted to quantify the mediation effects of urban characteristics and individual attributes on health risk perceptions among older adults.ResultsThe findings indicate that air quality dissatisfaction significantly predicts the willingness to relocate, especially in cities with high concentrations of pollutants like PM2.5, NO2, SO2, and CO. …”
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3008
Association of lysosomal protein transmembrane 4 beta gene polymorphism with pancreatic carcinoma susceptibility in the Chinese population
Published 2017-05-01“…The χ 2 test was used to analyze the differences of categorical variables and Hardy–Weinberg equilibrium. …”
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3009
The Influence of Principal Leadership and Teacher Self-Development on the Professional Competence of Public High School Teachers
Published 2025-08-01“…Employing a quantitative research approach with a correlational ex post facto design and a survey method, data were collected through validated Likert-scale questionnaires from a sample of 214 teachers, selected using purposive and proportionate stratified random sampling from a total population of 460 teachers. The data were analyzed using SPSS through simple and multiple linear regression, correlation, and coefficient of determination analysis. …”
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3010
Uncivil customers and work-family spillover: examining the buffering role of ethical leadership
Published 2025-07-01“…Methods We conducted a two-wave, time-lagged survey among 586 full-time service sector employees in South Korea. The data were analyzed using confirmatory factor analysis and hierarchical regression to test the hypothesized relationships between customer incivility, burnout, work-family conflict, and ethical leadership. …”
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3011
Neuropsychiatric adverse events in people with HIV initiating a new integrase strand transfer inhibitor-based regimen in Italy: findings from the NEURO-INSTI study
Published 2025-05-01“…IRs were calculated as number of first occurrences/100 person-years follow-up (PYFU). To identify risk factors for CNS/NP AEs occurrence, a Cox regression analysis for competing risks was used (hazard ratio, HR, and 95% CI), including variables associated with the outcome at a p level < 0.20 in the univariate analysis. …”
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3012
The role of irregular eating behaviors in metabolic dysfunction-associated steatotic liver disease: evidence from a multicenter cross-sectional study in China
Published 2025-08-01“…We employed logistic regression models to calculate the odds ratios (ORs) for MASLD associated with skipping breakfast, late dinner consumption, and their combination, after adjusting for key demographic, lifestyle, and metabolic factors. …”
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3013
Survival expectations in melanoma patients: a molecular prognostic model associated with aging
Published 2025-02-01“…The immunohistochemical analysis revealed that reduced expression of Epidermal Growth Factor Receptor (EGFR), along with increased expression of Activating Transcription Factor 2 (ATF2) and DNA Polymerase Delta 1 (POLD1), was linked to a worse prognosis. …”
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3014
Frecuencia de adenomas serrados sésiles en pacientes con antecedente de cáncer colorrectal detectados durante colonoscopias de vigilancia
Published 2025-07-01“…Logistic regression was carried out to search for factors related to SSA. …”
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3015
PD-1/PD-L1 inhibitors monotherapy vs. combination therapy in elderly advanced NSCLC: a real-world study and nomogram for survival prognosis
Published 2025-07-01“…Cox regression identified combination therapy as a protective factor (HR = 0.54, P < 0.001), while ECOG PS ≥ 2 (HR = 1.87, P = 0.002), liver metastasis (HR = 1.62, P = 0.013), bone metastasis (HR = 1.84, P < 0.001), and malignant pleural effusion (HR = 1.64, P < 0.001) independently worsened prognosis. …”
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3016
Serum PTH Associated with Malnutrition Determined by Bioelectrical Impedance Technology in Chronic Kidney Disease Patients
Published 2022-01-01“…High levels of PTH are an independent risk factor for developing low SMI in CKD patients.…”
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3017
Global Burden of Alzheimer’s Disease Attributable to High Fasting Plasma Glucose: Epidemiological Trends and Machine Learning Insights
Published 2025-04-01“…All rates were age-standardized. Joinpoint regression, age-period-cohort models, and ARIMA were employed to analyze trends and make future predictions. …”
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3018
ACO-NM hybrid optimization calculation method for transit time of oxygen activation logging in CO2 injection profile
Published 2025-08-01“…However, activation spectrum peaks in CO2 injection often exhibit single-peak tailing and double-peak overlapping, influenced by statistical fluctuations in activated gamma-ray count rates, fluid properties, multi-layer string structure, and other factors. As a result, accurately determining the transit time of activation spectra and evaluating the amount of CO2 uptake in each small layer becomes challenging.To minimize errors in transit time calculation caused by overlapping peak separation and activation peak boundary selection, the morphological characteristics of activation peaks under varying influences were analyzed meticulously. …”
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3019
Association of SNPs in carbohydrate metabolism genes with insulin resistance indicators in the Mexican population
Published 2025-07-01“…Associations between SNPs and metabolic traits were analyzed using logistic regression models adjusted for relevant covariates. …”
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3020
Predicting Postoperative Blood Transfusion in Elderly Patients Undergoing Total Hip and Knee Arthroplasty Using Machine Learning Models
Published 2025-05-01“…This study aimed to develop predictive models for postoperative transfusion in elderly patients undergoing THA or TKA, identify key risk factors, and create an online prediction tool.Patients and Methods: We retrospectively analyzed 1,520 elderly patients who underwent THA (659) or TKA (861). …”
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