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4581
Association of myeloid-derived suppressor cells with hematopoietic recovery after high-dose chemotherapy in multiple myeloma
Published 2023-06-01“…According to the data of multivariate analysis of variance, the number of transplanted CD34+ cells/kg and the number of M-MDSCs were significant factors for the duration of leukopenia. At the same time, such clinical parameters as the depth of response and minimal residual disease status before high-dose chemotherapy and hematopoietic stem cell transplantation, as well as the MM stage, did not affect the duration of hematopoietic recovery. …”
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4582
Association between menopause-related symptoms and muscle mass index among perimenopausal and postmenopausal women and the mediating role of estrogen levels
Published 2025-07-01“…After controlling for confounding factors such as age, educational level, menopausal stage, history of hypertension, follicle-stimulating hormone (FSH), and E2, KMI was negatively correlated with MMI (β=-1.612, 95% CI: -2.677 to -0.546, p=0.003). …”
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4583
Correlation Between the Online Visiting Time and Frequency Increase in Telemedicine Services Offered by Health Care Providers Before, During, and After the COVID-19 Pandemic in Chi...
Published 2025-02-01“…Chi-square tests were applied to compare general differences in the between-group telemedicine frequency. Regression models were performed to analyze correlations between the frequency change and the time spent in online versus in-person visits. …”
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4584
PREDICTORS OF THE DEVELOPMENT OF HYPOXIC-ISHEMIC ENCEPHALOPATHY IN FULL-TERM AND PREMATURE INFANTS BORNFROM MOTHERS WITH METABOLIC SYNDROME IN THE EARLY NEONATAL PERIOD
Published 2025-07-01“…Particular emphasis has been placed on the involvement of nitric oxide (NO) in the pathophysiology of HIE Objective: to analyze and identify risk factors for hypoxic-ischemic encephalopathy in full-term and premature infants born to mothers with metabolic syndrome, to build clinical prognostic models. …”
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4585
Real world treatment patterns for recurrent and metastatic head and neck cancer in the post-KEYNOTE 048 era
Published 2025-05-01“…Treatment group differences were assessed with chi-squared and t-tests, and selection factors were analyzed with logistic regressions. Survival was assessed with Kaplan-Meier curves, log-rank tests, and Cox regressions.ResultsOf 2577 patients included, Anti-PD1 monotherapy (n=1410) improved survival over cetuximab+chemotherapy (n=577, median survival 14.6 vs. 12.6 months, p=0.015), while anti-PD1+chemotherapy (n=590) showed a nonsignificant trend towards improvement (median survival 14.3 vs. 12.6 months, p=0.053). …”
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4586
Polymorphisms in the GNAS Gene as Predictors of Ventricular Tachyarrhythmias and Sudden Cardiac Death: Results From the DISCOVERY Trial and Oregon Sudden Unexpected Death Study
Published 2016-12-01“…Background Population‐based studies suggest that genetic factors contribute to sudden cardiac death (SCD). …”
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4587
Analysis of the inflammatory storm response and heparin binding protein levels for the diagnosis and prognosis of sepsis-associated encephalopathy
Published 2025-02-01“…In addition, the GCS score and serum cholinesterase levels in the SAE group were lower than in the non-SAE group (P < 0.05). Subsequently, Multi-factor logistic regression analysis revealed that ultra-high IL-6 (> 5000 pg/ml), IL-10 (> 1000 pg/ml), and HBP (> 300 ng/ml) levels and elevated SOFA and APACHE-II scores were risk cytokines for the development of SAE (P < 0.05). 28-day mortality was significantly higher in patients in the SAE group and in the IL-6 > 5000 pg/ml group compared to patients in the USAE and IL-6 < 5000 pg/ml groups(P < 0.001).The four screened predictors of HBP > 300 ng/ml, IL-6 > 5000 pg/ml, decreased GCS score, and decreased APACHEII score were combined into a new predictive data model (risk score).In the SAE group, patients with high risk scores had a higher 28-day mortality rate compared with the low risk score group (P < 0.001). …”
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4588
Long-term air pollution exposure and cardiovascular disease progression in rheumatoid arthritis: A prospective cohort study using multi-state model analysis
Published 2025-05-01“…However, the impact of environmental factors on RA progression remains unclear. This study aimed to explore the link between long-term air pollution exposure and the multi-stage progression from a healthy status to RA onset, then CVD development, and finally death. …”
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4589
Association Between Systemic Immune-Inflammation Index in Early Pregnancy and Preeclampsia: A Multicenter Cohort Study
Published 2025-06-01“…Multivariable logistic regression and smooth fitting curves were used to analyze the relationship between SII and PE. …”
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4590
Prognostic value of a lncRNA signature in early-stage invasive breast cancer patients
Published 2025-06-01“…Subsequently, employing the LASSO Cox regression model with five lncRNA features as covariates, we constructed a five-lncRNA signature. …”
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4591
The Serum Level of IL-1B Correlates with the Activity of Chronic Pulmonary Aspergillosis
Published 2018-01-01“…Then, 381 cases with factors significantly affecting IL-1B expression was excluded through multiple linear regression; the remaining 88 patients were divided into high IL-1B group and low IL-1B group, according to the median value of serum IL-1B, for subgroup analysis. …”
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4592
Steroids combined with anticoagulant in acute/subacute severe cerebral venous thrombosis
Published 2025-08-01“…After adjusting for confounding factors, the result remained consistent. Pulsed steroid therapy did not increase mortality during hospitalization or follow-up, nor did it lead to severe steroid-related complications (all P >0.05). …”
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4593
The global impact of non-alcoholic fatty liver disease (including cirrhosis) in the elderly from 1990 to 2021 and future projections of disease burden.
Published 2025-01-01“…This dataset includes incidence rates of NAFLD. The Joinpoint regression model was utilized to detect turning points in the epidemiological trends of NAFLD, and decomposition analysis was performed to analyze the factors influencing these trends. …”
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4594
Endoscopic management of large laterally spreading colorectal tumors (LSTs): a comparative study of techniques and outcomes
Published 2025-06-01“…To compare EMR, pEMR, ESD, and hybrid ESD with respect to complication rates (bleeding, perforation), recurrence, and influencing factors. Materials and methods. In this single-center, retrospective-prospective study, 100 adult patients with non-invasive LSTs larger than 20 mm were enrolled. …”
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4595
Dietary attribution to burden of chronic disease in Australia: a systematic analysis of the Australian Institute of health and welfare 2024 national burden of disease datasetResear...
Published 2025-09-01“…Since the 2024 death counts were missing, total mortality attributable to dietary risks was expressed as the percentage change from 2003 to 2018. Joinpoint Regression was performed to assess DALYs, YLLs, and YLDs of NCDs from 2003 to 2024, analyze the contribution of various dietary risk factors to the disease burden and conduct subgroup comparisons based on sex. …”
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4596
Navigating the shadows: the impact of mindfulness, cognitive fusion, and coping strategies on psychological distress among mental health workers in Timor Leste
Published 2025-08-01“…Descriptive statistics, Pearson correlation coefficients, and multiple regression analyses were used to analyze the data. Results Significant positive correlations were found between Depression and Anxiety (Spearman’s rho = 0.649, p < 0.001), and between Depression and Stress (Spearman’s rho = 0.753, p < 0.001). …”
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4597
Spatial variations and determinants of modern contraceptive utilization among sexually active rural women in Ethiopia using mini EDHS 2019 data: spatial and multilevel analysis
Published 2025-05-01“…Multilevel multivariable logistic regression was employed to identify factors associated with modern family planning utilization in Ethiopia. …”
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4598
[Artículo traducido] El índice de comorbilidad de Charlson ajustado por la edad en las fracturas acetabulares de los pacientes ancianos
Published 2025-07-01“…Abstract: Objective: This study aimed to analyze factors of comorbidity in older patients with acetabular fracture to know the role of disease in the treatment of this population. …”
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4599
Global, regional and national burden of echinococcosis in 204 countries and territories from 1990 to 2021: A systematic analysis based on the Global Burden of Disease Study 2021
Published 2025-08-01“…The study aimed to systematically analyze the burden of echinococcosis from 1990 to 2021. …”
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4600
Cropping Practices and Effects on Soil Nutrient Adequacy Levels and Cassava Yield of Smallholder Farmers in Northern Zambia
Published 2021-01-01“…To explain yield differences within the same cassava growth stage group, the data were grouped into low- and high-yield categories using the median, before applying a nonparametric test for one independent sample. Stepwise regressions were performed on each growth stage and the whole dataset to determine factors affecting tuber yield. …”
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