Predictive value of preclinical models for CAR-T cell therapy clinical trials: a systematic review and meta-analysis by Sebastian Kobold, Carsten Marr, David Andreu-Sanz, Lisa Gregor, Emanuele Carlini, Daniele Scarcella

“…While the logistic regression model accurately predicted clinical outcomes based on clinical or preclinical features (Macro F1 and area under the curve (AUC)>0.8), it failed in predicting preclinical outcomes from preclinical features (Macro F1<0.5, AUC<0.6), indicating that preclinical studies may be influenced by experimental factors not accounted for in the model.Conclusion These findings underscore the need to better understand the experimental factors enhancing the predictive accuracy of mouse models in preclinical settings.…”
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Determinants of residential satisfaction: an actual-aspiration gap theory analysis in low-cost condominium housing, Addis Ababa, Ethiopia by Lissanework Sileshi Alemu, Wubshet Berhanu, Daniel Lirebo Sokkido

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Long‐term survival analysis of patients with non‐small cell lung cancer complicated with type 2 diabetes mellitus by Gaoxiang Wang, Xuejiao Li, Ran Xiong, Hanran Wu, Meiqing Xu, Mingran Xie

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Assessing urban spatial vitality in post-port areas: a multimodal data analysis of Shanghai, Liverpool, and Marseille by Chen Zeng, Tianchen DAI, Feng Wang, Jiangyue Wu

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Subject-Independent Cuff-Less Blood Pressure Monitoring via Multivariate Analysis of Finger/Toe Photoplethysmography and Electrocardiogram Data by Seyedmohsen Dehghanojamahalleh, Peshala Thibbotuwawa Gamage, Mohammad Ahmed, Cassondra Petersen, Brianna Matthew, Kesha Hyacinth, Yasith Weerasinghe, Ersoy Subasi, Munevver Mine Subasi, Mehmet Kaya

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A latent profile analysis of cancer survivors’ return to work adaptability and the associations between its’ categories and financial toxicity by Xiaoyun Hu, Weiya Dong, Hongya Zhao, Ying Chen, Yue Shi, Qigang Zhou, Suyun Huang

“…Cancer survivors’ return to work adaptability was categorized using potential profile analysis. Financial toxicity was analyzed using multivariate logistic regression in potential categories. …”
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Treatment and outcomes in children with multidrug-resistant tuberculosis: A systematic review and individual patient data meta-analysis. by Elizabeth P Harausz, Anthony J Garcia-Prats, Stephanie Law, H Simon Schaaf, Tamara Kredo, James A Seddon, Dick Menzies, Anna Turkova, Jay Achar, Farhana Amanullah, Pennan Barry, Mercedes Becerra, Edward D Chan, Pei Chun Chan, Domnica Ioana Chiotan, Aldo Crossa, Peter C Drobac, Lee Fairlie, Dennis Falzon, Jennifer Flood, Medea Gegia, Robert M Hicks, Petros Isaakidis, S M Kadri, Beate Kampmann, Shabir A Madhi, Else Marais, Andrei Mariandyshev, Ana Méndez-Echevarría, Brittany Kathryn Moore, Parpieva Nargiza, Iveta Ozere, Nesri Padayatchi, Saleem- Ur-Rehman, Natasha Rybak, Begoña Santiago-Garcia, N Sarita Shah, Sangeeta Sharma, Tae Sun Shim, Alena Skrahina, Antoni Soriano-Arandes, Martin van den Boom, Marieke J van der Werf, Tjip S van der Werf, Bhanu Williams, Elena Yablokova, Jae-Joon Yim, Jennifer Furin, Anneke C Hesseling, Collaborative Group for Meta-Analysis of Paediatric Individual Patient Data in MDR-TB

“…All data were from published or unpublished observational cohorts. We analyzed demographic, clinical, and treatment factors as predictors of treatment outcome. …”
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Analysis of age-related survival differences in advanced non-small cell lung cancer patients based on real-world data by Feiyang Li, Fang Li, Haowei Lu, Dong Zhao

“…Median cancer-specific survival was 21 months for the ≥ 70 years group and 17 months for the < 70 years group (HR = 0.892, 95% CI 0.716–1.112, P = 0.298). Cox regression analyses revealed that age was not an independent prognostic factor for survival. …”
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Oncological outcomes, survival analysis, and failure patterns in patients with resectable squamous cell carcinoma of the oral tongue treated with glossectomy by Hadi A. Al-Hakami, Atheer Ali Al-Talhi, Bassam AlRajhi, Mohammad A. Alshareef, Baraa I. Awad, Tanvir Hussain, Mohammed Al-Garni

“…Data on demographics, clinical characteristics, treatment modalities, and oncological outcomes were collected and analyzed. Statistical analyses including Kaplan–Meier survival curves and Cox regression were employed to evaluate survival and recurrence. …”
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Analysis of the diagnostic value of NLR and PLR in cervical lymph node metastasis of tongue squamous cell carcinoma before surgery by CHENG Longlong, ZHANG Shihan, MENG Xin, ZHANG Jingrui, ZHOU Ying, WANG Yonggong

“…Multivariate logistic regression analysis showed that NLR is an independent influencing factor for cervical lymph node metastasis in TSCC patients. …”
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Burn Injuries in Primary School Children: A Multicenter Epidemiological Study Between 2009 and 2023 by Abdolkhalegh Keshavarzi, S. Yasamin Parvar, Mandana Goodarzian, Aram Maaroufi, MReza Goodarzian, Gholam Reza Motazedian, Mitra Zardosht

“…Data were extracted from the burn research data center and analyzed using univariate and multivariate logistic regression analyses to identify independent survival predictors in children aged 7–14 years over a 14‐year period admitted to the Amir‐al‐Moemenin and Ghotb al‐Din‐e‐Shirazi burn hospitals. …”
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Identification of Pyroptosis-Relevant Signature in Tumor Immune Microenvironment and Prognosis in Skin Cutaneous Melanoma Using Network Analysis by Yun Zhu, Dan Han, Hongjue Duan, Qi Rao, Yike Qian, Qiaoyun Chen, Xiao Du, Huanyu Ni, Siliang Wang

“…In addition, a prognostic pyroptosis-related signature (PPRS) model was constructed by performing Cox regression, weighted gene coexpression network analysis (WGCNA), and least absolute shrinkage and selection operator (LASSO) analysis to score SKCM patients. …”
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Thyroiditis and human blood metabolites: A mendelian randomization study by Shao Lijie, Liu Siqi, Song Yongfu, Han Shaoyu, Ma Yue, Kunpeng Yang, Zhang Jingbin, Qi Bingxue, Guo Yan, Lu Xiaodan

“…Background: The risk factors for thyroiditis, an inflammatory disease with a complex etiology, remain poorly understood. …”
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Global and regional burden of four drug use disorders in the elderly, 1990 to 2021: an analysis of the global burden of disease study by Bochao Jia, Rui Wei, Zhiqi Li, Meiyu Feng, Mengxue Wang, Chongjun Zhao, Yi Wei, Zhenquan Liu, Yuanhui Hu

“…High-income North America, represented by the United States, shows a higher burden of disease. Decomposition analysis shows that population growth is the main factor affecting the change in the burden of DUDs in most regions, and high-income North America is mainly affected by epidemiological changes. …”
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Changes in prescribing patterns and access to immune checkpoint inhibitors in german lung cancer patients – a claims data analysis by Julia Walter, Blerina Resuli, Laura Sellmer, Diego Kauffmann-Guerrero, Toki Bolt, Chukwuka Eze, Jürgen Behr, Amanda Tufman

“…We included pre-treated patients with advanced disease. Factors potentially influencing the adoption of ICI therapies were analyzed, including demographics, residence type, hospital size, comorbidities, and metastasis location. …”
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Clinical prognosis evaluation of alpha-fetoprotein-positive gastric cancer: comprehensive analysis and development of a novel nomogram for survival prediction by Fei Zuo, Yunyan Tan, Wenjun Mao, Zhaoqing Tang, Tianping Luo

“…Multivariate Cox regression confirmed AFP positivity as an independent prognostic factor (adjusted HR = 1.8, 95% CI: 1.03–3.14, p =0.04), alongside T4-stage, N3-stage, and distant metastasis. …”
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Integrating mindfulness and physical activity: a meta-analysis of mindful movement interventions for symptoms of anxiety and depression among university students by Xinjian Xu, Borhannudin Bin Abdullah, Shamsulariffin Bin Samsudin, Yongneng Tan

“…It supports treating mindful movement as a unified approach to analyzing its impact on mental health. Residual heterogeneity highlights the need for further research on specific intervention elements and intervention and participant-related factors. …”
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Global inequalities in arts, music or educational organization membership: an epidemiological analysis of 73,825 adults from 51 countries by Hei Wan Mak, Jessica K. Bone, Taiji Noguchi, Joeun Kim, Rina So, Emma Walker, Calum Smith, Marlee Bower, Ferdi Botha, Nisha Sajnani, Nils Fietje, Daisy Fancourt

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Impact of tertiary lymphoid structure-associated biomarkers on pancreatic cancer via a dual-disease analysis of psoriasis and pancreatic cancer by Hao Yu, Quan Yuan, Liu-Xing Feng, Jia-Huan Xu, Shen-Yuan Zhan, Zhi-min Li, Shuang-Jia Wang

“…Gene expression profiles from public databases were analyzed, and TLS-associated genes were subjected to Cox regression and Kaplan-Meier analyses. …”
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Decomposition analysis of public health service utilization and health disparities among urban and rural older adult migrants in China by Bo Dong, MengHan Jiang, Jing Zong

“…However, their self-reported health status was significantly lower (76.88% vs. 79.12%). Regression analysis revealed that age, mobility range, education level, income, health insurance coverage, and geographic region were significant factors influencing both service utilization and health outcomes. …”
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