The correlation between serum adiponectin and hypoxia-inducible factor-1 in patients with diabetic nephropathy by ZHANG Zhi-qin, WEI Mao-bi, WANG Bai-ying, CHEN Wei, WU Xiao-yan

“…Diagnostic criteria of diabetic nephropathy referred to Expert Consensus on Prevention and Treatment of Diabetic Nephropathy(2014 edition).The control group(CN) consisted of 23 patients with only oblique hernia or intestinal polyps without other symptoms.The diabetic nephropathy group was divided into macroalbuminuria subgroup(10 patients) and microalbuminuria subgroup(37 patients) according to the urinary protein excretion(UAER).The remaining 18 patients were non-albuminuria.The DKD group meeting the criteria of diabetic retinopathy with any stage of chronic kidney disease was included in the retinopathy group.However,since there was also a retinopathy subgroup in the proteinuria group,the cumulative number of retinopathy subgroup was 26 patients.The standard of the macroalbuminuria subgroup was urinary albumin>300 mg/24 h or(+++)or above,while the standard of the microalbuminuria subgroup was ualbumin <300 mg/24 h or(++)or below.The differences and correlations of serum adiponectin and HIF-1α between the two groups and their subgroups were analyzed to explore their clinical significance.Results Serum adiponectin and HIF-1α levels in the diabetic nephropathy group were higher than those in CN group,and serum adiponectin in the DKD group was 3808 ng/L(3625,4164) vs.CN group 2954 ng/L(2439,3809)(P<0.01);serum HIF-1α in the DKD group was 130.44 ng/L(119.50,143.08) vs.CN group 98.32 ng/L(88.04,117.71)(P<0.01).At the same time,linear regression analysis showed that serum ADPN level was positively correlated with hif-1α,with R correlation coefficient=0.961,slope=26.29,and P<0.01.Moreover,the detection efficiency of serum adiponectin and hif-1 to DKD was 0.747 and 0.776,respectively,and P<0.01.Conclusion Serum adiponectin level is increased and positively correlated with HIF-1α in diabetic nephropathy,and serum adiponectin and HIF-1α may have correlative mechanism worthy of exploration.Serum ADPN may be co-involved in the progression of diabetic nephropathy by relating to hypoxia in the body.…”
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Back to the basics–risk factor identification of pediatric malignant lymphadenopathy proven by pathological studies by Wei-Hsiang Su, Cheng-Che Wu, Chia-Man Chou, Sheng-Yang Huang, Hou-Chuan Chen

“…Weight loss, fixed LAP, firm consistency, and serum lactate dehydrogenase (LDH) exceeding 240 U/L were more related to malignant LAP than other risk factors. Multiple regression analysis revealed two independent risk factors. …”
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Psoriasis is the independent factor for early atherosclerosis: A prospective study of cardiometabolic risk profile by Dinić Miroslav Ž., Zečević Radoš D., Hajduković Zoran, Mijušković Mirjana, Đurić Predrag, Jović Zoran, Grdinić Aleksandra, Petrović Mirjana, Terzić Brankica, Pejović Janko, Kandolf-Sekulović Lidija

“…In multivariate logistic regression analysis, after the adjustment for confounding variables, the most important predictor of CIMT and FIMT was the diagnosis of psoriasis (p < 0.001). …”
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SELF-DISCLOSURE OF ADOLESCENTS AS THE MOST INFLUENTIAL FACTOR IN THE PROVISION OF REPRODUCTIVE HEALTH INFORMATION TO ADOLESCENTS by Tanjung Anitasari Indah Kusumaningrum, Muhamad Taufik Hidayat, Anny Fauziyah, Rahmawati Setyaningrum, Tasya Aulianisa Hidayat, Mayang Widya Saputri

“…Aims: This study aimed to analyze the factors that most influence parent-to-adolescent communication regarding reproductive health. …”
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Prognostic role of epidermal growth factor receptors’ expression in patients with i-ii stage of non-small cell lung cancer by A.P. Kolesnik, A.I. Shevchenko, V.A. Tumansky, A.V. Evseev, M.A. Shishkin

“…Objective: The aim of our work was to determine the connection of clinical and morphological patients’ characteristics with the expression of epidermal growth factor receptors of 1 and 2 types (EGFR, HER-2-neu) and also to analyze the influence of these factors on patients survival with early stages (I-II) of non-small cell lung cancer (NSCLC). …”
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Associations of Urine Epidermal Growth Factor With Kidney and Cardiovascular Outcomes in Individuals With CKD in SPRINT by Merve Postalcioglu, Ronit Katz, Simon B. Ascher, Trenton Hall, Pranav S. Garimella, Stein I. Hallan, Joachim H. Ix, Michael G. Shlipak

“…A linear mixed-effects model was used to investigate the associations of uEGF with the annual eGFR change; Cox proportional hazards regression models were used to analyze its associations with the ≥30% eGFR decline, CVD, and all-cause mortality outcomes. …”
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Large-Scale Embryo Transfer Operation in Dromedary Camels: Retrospective Analysis of the Association Between Key Clinical Factors and the 2-Month Pregnancy Rate by Taher Kamal Osman, Sayed Taha Ismail, Hossam R. El-Sherbiny

“…A total of 4360 embryos were transferred to 2947 recipients in this study. Logistic regression analysis (binary) was applied to evaluate the association between the selected factors and PR in month two. …”
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Analysis of characteristics among unemployed callers to the psychological support hotline in Beijing by Xingxue Li, Xingxue Li, Xingxue Li, Zikang Liu, Zikang Liu, Zikang Liu, Tong Wu, Tong Wu, Tong Wu, Zhe Yuan, Zhe Yuan, Zhe Yuan, Wei Wang, Liting Zhao, Liting Zhao, Shuchang Yang, Hong Liang, Hong Liang

“…This study analyzes characteristics and mental health status of unemployed callers through psychological support hotline data, aiming to identify underlying psychological risk factors.MethodsA retrospective analysis was conducted on the general demographic data, primary concerns, and mental health status of unemployed callers to the Beijing Psychological Support Hotline from 2020 to 2023. …”
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Risk Factors for Acute Exacerbation in Patients with COPD Group E in Ningbo: Risk Analysis of Irregular Review, Cardiovascular Complications, and Lung Function Decline by Qian Y, Sun C, Zhang L, Cai C, Sun M, Zhang J, Huang J, Ma H, Tan L, Zhao Y, Wang S, Lv D

“…Yang Qian,1 Chao Sun,1 Liang Zhang,2 Chenting Cai,1 Mengqing Sun,1 Jiaqian Zhang,1 Jian Huang,3 Hongying Ma,1 Lin Tan,1 Yun Zhao,1 Shanshan Wang,1 Dan Lv1 1The First Affiliated Hospital of Ningbo University, Ningbo, 315010, People’s Republic of China; 2Ningbo Municipal Center for Disease Control and Prevention, Ningbo, 315000, People’s Republic of China; 3School of Big Data and Software Engineering, Zhejiang Wanli University, Ningbo, 315100, People’s Republic of ChinaCorrespondence: Dan Lv, The First Affiliated Hospital of Ningbo University, 59 Liuting Street, Ningbo City, Zhejiang Province, People’s Republic of China, Email fylvdan@nbu.edu.cnObjective: To understand the high-risk factors for disease progression in patients in the chronic obstructive pulmonary disease (COPD) group E in Ningbo, and to explore the impact of and treatment on the prognosis of these patients.Methods: We retrospectively analyzed the clinical data of 101 COPD patients in terms of general demographics, physical baseline data, lung function, disease treatment, and prognosis and used crosstab analysis and logistic regression analysis to understand the characteristics of the population of patients at high risk of acute exacerbation of COPD (AECOPD) and the associated risk factors.Results: Univariate analysis demonstrated that frequent acute exacerbation (AE) in the COPD group E population was significantly associated with more severe airflow limitation, a lower FEF75%, higher mMRC scores, and irregular disease management (P&lt; 0.05). …”
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Trends and factors associated with anemia among women of reproductive age in Mali: analysis of data from 2001 to 2018 Mali demographic and health surveys by Ebenezer Kwesi Armah-Ansah, Eugene Budu, Charity Oga-Omenka, Marina Kolosnitsyna

“…We included a total weighted sample of 18,096 women of reproductive age who had participated in the hemoglobin test. Multilevel regression analysis was employed, and the results were presented as adjusted odds ratio (aOR), with 95% confidence intervals (CIs) and p-values used to show the results. …”
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Empirical Examination of the Interactions Between Healthcare Professionals and Patients Within Hospital Environments—A Pilot Study by Dimitris Charalambos Karaferis, Dimitris A. Niakas

“…According to the findings from the two-stage least squares (2SLS) regression analysis, an essential method for researchers addressing endogeneity challenges in structural equation modeling, an increase of 1 point in the job satisfaction of physicians is associated with a corresponding positive increase of 1.12 points in patient satisfaction. …”
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The grit personality trait, eating behavior, and obesity among Japanese adults: a cross-sectional study by Noriaki Kurita, Takako Maeshibu, Tetsuro Aita, Takafumi Wakita, Hiroe Kikuchi

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Factors of Financial Imbalance in the Compulsory Pension Insurance System: the Case of Russia by A. l. Safonov, Yu. V. Dolzhenkova

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Predicting Olympic Medal Performance for 2028: Machine Learning Models and the Impact of Host and Coaching Effects by Zhenkai Zhang, Tengfei Ma, Yunpeng Yao, Ningjia Xu, Yujie Gao, Wanwan Xia

“…Factor analysis is used to reduce them into three principal components: Factor analysis condenses ten influencing factors into three principal components: the event scale factor (F1), the medal trend factor (F2), and the gender and athletic ability factor (F3). …”
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Analysis of the Clinical Molecular Characteristics and Neoadjuvant Chemotherapy Response in Patients with Human Epidermal Growth Factor Receptor 2-Negative Breast Cancer and Axilla... by Jin-Ping Ma, Yong Zhang, Sheng Fang, Jian Zhang, Jia-Hong Zhang, Teng Wang, Yuan Ma, Hai-Bo Wang

“…Univariate analysis was conducted using the χ2 test, and multivariate analysis was conducted using logistic regression analysis. …”
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Role and Risk Factors of Glycosylated Hemoglobin Levels in Early Disease Screening by Guanqun Chao, Yue Zhu, Liying Chen

“…Logistic regression analysis was used to analyze the risk factors of HbA1c. …”
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Evaluation of Factors Associated with Fatality in Hospitalized Patients with Clostridioides difficile Infection by Sinan Çetin

“…Demographic and clinical data were compared between the two groups. The risk factors for 30 day fatality were analyzed through logistic regression and Kaplan-Meier (KM) survival analysis. …”
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The Relationship of Clinical and Laboratory Factors with Acute Isolated Vertigo and Cerebellar Infarction by Cihan Bedel, Mustafa Korkut

“…The multivariate logistic regression analysis revealed that hyperlipidemia (odds ratio [OR] = 3.233; 95% confidence interval [CI] = 1.144–9.136; P = 0.027) and imbalance (OR = 4.064; 95% CI = 1.271–12.995; P = 0.018) were the strongest indicators of cerebellar infarction in the patients with isolated vertigo. …”
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Factors Associated With the 30-day Readmission Rate in Patients With Heart Failure by Fereshteh Rezvani, Zahra Abbasi Dolatabadi, Maryam Esmaeili, Saman Maroufizadeh, Mohammad Garakyaraghi, Monir Mazaheri

“…The information was collected using a researcher-made form that surveyed sociodemographic characteristics, clinical characteristics, common drug treatments and discharge conditions. The data were analyzed using inferential statistics, including t-test, chi-square test/Fisher’s exact test and multiple logistic regression analysis. …”
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Spatiotemporal dynamics and influencing factors of soil heterotrophic respiration in northeast China. by Dan Liu, Cheng Long Yu, Rui Feng, Shi Ping Yin

“…Using meteorological data, DEM, soil organic carbon density, and other data, we simulated the Rh in Northeast China from 2001 to 2020 using the GSMSR model. We then analyzed its spatialtemporal distribution pattern and examined its spatial-temporal aggregation, differentiation characteristics, and influencing factors at the national level, employing methods such as standard deviation ellipse (a statistical method that describes the spread and direction of data points in space), cold-hot spot analysis, and geographically weighted regression. …”
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