Predicting recurrence of non-muscle invasive bladder urothelial carcinoma: predictive value of the optimal cut-off value of Ki67 by Rende Peng, Yaoyu Zhang, Mingzhu Jia, Xinping Yi, Xiaoyao Yi, Shadan Li, Jiangchuan Pi, Wenjun Meng

“…Univariate and multivariate regression analysis were used to analyze the relationship between the expression of Ki67 and postoperative recurrence of NMIBUC. …”
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25-hydroxyvitamin D as a predictor of reduced heart rate variability in elderly patients with diabetes mellitus by Tiantian Tang, Xinyu Sun, Xiaoxiang Zhang, Jiaojiao Li, Manjie Wang, Cancan Hui, Yuwei Cheng, Xiaoming Kong, Yan Sun

“…Statistical analyses included χ² test, independent t-test, Mann-Whitney U test, and multivariate logistic regression to identify risk factors for HRV reduction. …”
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The influence of buyer knowledge and economic level on sports product purchasing decisions by Ilham Ilham, Raihan Alfarobi Raihan, Bekir Erhan Orhan, Vlad Adrian Geantă Geantă

“…Hypotheses were tested through linear regression analysis with a significance threshold of p < 0.05. …”
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BDNF/TrkB signaling in stable coronary artery disease by O. V. Atamas, M. V. Antonyuk, T. P. Novgorodtseva, T. A. Gvozdenko, O. Yu. Kytikova

“…Cluster, correlation, and regression analyzes were used.Results. In patients with CAD, a wide range of variations in BDNF concentrations was observed. …”
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Impact of long working hours on insomnia, anxiety, and depression symptoms among employees of eight manufacturing enterprises in Shenzhen by Yingping XIANG, Juntao HE, Zihuang XIE, Wei ZHOU, Yeen HUANG

“…Participants were classified into two groups based on working hours: long working hours (≥55 h per week) and normal working hours (35-40 h per week). Binary logistic regression was used to analyze the association between long working hours and the occurrences of insomnia, anxiety, and depression symptoms.ResultsA total of 1491 manufacturing industry employees were included in the study (response rate: 97.8%). …”
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Burdens of sense organ diseases across global, regional, and national levels from 1990 to 2021 and projections for 2050 by Min-Jun Zhao, Jian-Li Yin, Yang-Shuo Ge, Jia-Ying Ding, Chun-Meng Huang, Ting-Ting Meng, Cai Zhang, Xu-Bo Wu, Jian-Ju Liu, Dao-Fang Ding

“…Methods We analyzed prevalence, disability-adjusted life years (DALYs), and age-standardized rates using Joinpoint regression and age-period-cohort (APC) models to separate the effects of age, period, and birth cohort. …”
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A correlation research of Ki67 index, CT features, and risk stratification in gastrointestinal stromal tumor by Huali Li, Gang Ren, Rong Cai, Jian Chen, Xiangru Wu, Jianxi Zhao

“…The multivariate logistic regression analysis revealed that the tumor size [P = 0.043 Exp (B) = 1.150] and the presence of ulceration [P = 0.011, Exp (B) = 3.669] were effective variables in distinguishing between the groups with Ki67 ≤ 5% and >5%. …”
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A longitudinal study on sleep quality of patients with stage 4 chronic kidney disease,subject to hemodialysis and peritoneal dialysis by LUO Min-hong, YUAN Li-ping, CHEN Qiu-lian, ZHU Lang-jing, ZENG Hai-ou, CHEN Zhen-wei, WU Qiang, YANG Tie-cheng

“…Objective A longitudinal research was conducted in our center to observe the dynamic change of sleep quality of patients with stage 4 chronic kidney disease(CKD),subject to hemodialysis and continuous ambulatory peritoneal dialysis(CAPD) and to investigate the associated factors.Methods Patients with CKD stage 4(n = 43),hemodialysis(n = 41) and CAPD(n = 44) were included and followed up for 1 year.Pittsburgh Sleep Quality Index(PSQI) and laboratory parameters were evaluated every 6 months.The univariate and multivariate Logistic regression analysis was used to analyze the associated factors.Results There was no significant difference in age,sex,socio-economic factors,smoking,BMI,Charlson comorbidity index and primary renal disease among the three groups(P>0.05).At the baseline and sixth month,the PSQI scores in hemodialysis and CAPD groups were significantly higher than those in CKD stage 4 group(P<0.05).At the twelfth month,there was no significant difference in PSQI scores among the three groups(P<0.05).As compared with the baseline values,the PSQI scores among the three groups at the sixth month were all significantly increased(P<0.05).As compared with the values at sixth month,the PSQI scores in CKD stage 4 group at the twelfth month were significantly increased(P<0.05),and those in hemodialysis and CAPD groups had no significant change.With the dynamic changes of the total PSQI score,hemoglobin,calcium and phosphorus product,intact parathyroid hormone and high-sensitivity C-reactive protein also changed in the three groups.Age(OR=1.83,P=0.01),hemoglobin(OR=1.46,P=0.01),calcium and phosphorus product(OR=1.25,P=0.02),intact parathyroid hormone(OR=1.17,P=0.03),and high sensitivity C-reactive protein(OR=1.32,P=0.04)were significantly related to poor sleep.Conclusions The sleep quality of patients with CKD stage 4,subject to hemodialysis and CAPD progressively deteriorated.Older age,anemia,the disorders of calcium phosphate metabolism and the microinflammatory status are the independent risk factors of poor sleep quality.…”
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The association between a body shape index and diabetic kidney disease in early-onset type 2 diabetes: evidence from a two-center study by Mengdie Chen, Yiyun Wang, Ping Feng, Lijing Wu, Hanying Liu, Yao Liang, Mengyao Yang, Qidong Zheng

“…BackgroundEarly-onset type 2 diabetes mellitus (T2DM) is closely associated with an increased risk of diabetic kidney disease (DKD), and obesity is a well-recognized contributing factor. Traditional measures like body mass index (BMI) have limitations in capturing visceral fat distribution. …”
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HBXIP suppression reduces cell proliferation and migration and its overexpression predicts poor prognosis in non-small-cell lung cancer by Yixuan Wang, Nan Li, Shuanlong Che, Tiefeng Jin, Junjie Piao, Shuangping Liu, Zhenhua Lin

“…Moreover, multivariate analysis suggested that HBXIP emerged as a significant independent prognostic factor along with clinical stage in patients with non-small-cell lung cancer. …”
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Prognostic Significance of Inflammatory and Nutritional Indices for Serous Ovary Cancer by Yan Han, Weiqin Lv, Jianfei Guo, Yun Shang, Fan Yang, Xiaomin Zhang, Keyuan Xiao, Liang Zong, Wenqing Hu

“…The survival of the patients was assessed utilizing the Kaplan-Meier method to analyze overall survival (OS). Additionally, a multivariate analysis employing the Cox proportional hazard regression model was conducted to identify the independent prognostic factors for SOC. …”
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Making the connection: social networks and type 2 diabetes among Black/African American Men: mixed-methods study protocol by Tyler Prochnow, Tyler Prochnow, Tyler Prochnow, Matthew Lee Smith, Matthew Lee Smith, Matthew Lee Smith, Megan S. Patterson, Jeong-Hui Park, Ledric D. Sherman, Ledric D. Sherman

“…Quantitative data will be analyzed using multivariate and multilevel regression techniques, while qualitative data will undergo thematic analysis. …”
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Impact of mixed plantation strategies on the nutrient concentrations of green and senescent leaves and their nutrient resorption efficiencies in temperate forests of the Loess Hill... by Senbao Lu, Senbao Lu, Senbao Lu, Senbao Lu, Yunming Chen, Yunming Chen, Yunming Chen, Jordi Sardans, Jordi Sardans, Josep Peñuelas, Josep Peñuelas

“…Further, a random forest model analysis showed that soil available P was main factor driving GLNC for individual rather than all species. …”
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Cytokine Signatures as Biomarkers of Clinical Remission in Rheumatoid Arthritis by Su W, Xiao Y, Chen X, Wu Y, Wu B, Yang Q, Peng B, Tang J, Yang Y

“…All the 12 cytokines examined were significantly associated with non-remission of RA in both Spearman correlation analysis (ρ=0.28~0.58, P&lt; 0.017) and univariate logistic regression analysis (OR=1.005~1.546, all P&lt; 0.05). …”
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Thirty-Year Trends (1991-2020) in Breast Cancer Incidence Rates: Hanoi, Vietnam by Giang Nguyen Huong, Hoa L. Nguyen, Robert J. Goldberg, Mara M. Epstein, Jeroan J. Allison, Loc Quang Pham, Le Minh Giang, Sang Minh Nguyen, Ngoc Dac Nguyen, Linh Thi Thuy Nguyen, Quang Le Van, Thuan Tran Van, Tran Thanh Huong

“…PURPOSEBreast cancer is the most common cancer in Vietnam, yet there are limited data on long-term trends and factors influencing its incidence. This study examines 30-year trends (1991-2020) in breast cancer incidence among women in Hanoi, focusing on age, period, and cohort effects.METHODSData from 28,298 breast cancer cases registered in the Hanoi Cancer Registry between 1991 and 2020 were analyzed. …”
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Elevated CD4⁺/CD8⁺ ratio and D-dimer as diagnostic biomarkers for Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis versus infectious mononucleosis in children: a re... by Yun Cheng, Wenjia Tong, Wangqiang Li, Yuanyuan Duan, Jingjing Jin, Biquan Chen

“…These parameters, along with clinical and laboratory features, were compared between the EBV-IM and EBV-HLH groups. Binary logistic regression was used to analyze the risk factors for the progression of EBV infection to EBV-HLH. …”
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Impact of pelvic lymph node dissection on survival outcomes in non-muscle invasive bladder cancer: a multicenter retrospective study by Shiwang Huang, Kaipeng Jia, Jingmin Cui, Jianfei Duan, Xiaosong Li, Wang Chai, Chong Shen, Zhe Zhang, Huitong Chen, Shan Liang, Jingwen Han, Jianing Guo, Zhouliang Wu, Yunkai Qie, Hailong Hu

“…Survival outcomes, including cancer-specific survival (CSS) and recurrence-free survival (RFS), were compared using Kaplan-Meier analysis and Cox proportional hazards models, while factors associated with upstaging were examined through logistic regression. …”
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A nomogram integrating clinical stage and pre-EBV DNA to identify the cycles of induction chemotherapy for locoregionally advanced nasopharyngeal carcinoma by Sunqin Cai, Zongwei Huang, Zihan Chen, Ying Li, Jingjing Su, Ronghui Chen, Siqi Xu, Jing Wang, Sufang Qiu

“…Prognostic determinants were identified through multivariate cox regression analysis. A nomogram model was constructed to quantify individualized prognosis. …”
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Maize Plant Morphology Affects Resistance to Stalk Breaking by Affecting Plant Stress by Yujie Cao, Ming Tian, Shang Gao, Bo Ming, Keru Wang, Haibing Yu, Shaokun Li, Jun Xue

“…Maize lodging resistance is determined by the plant’s wind-induced stress and the stalk’s mechanical strength, yet the factors influencing plant stress remain unclear. This study analyzed the quantitative relationship between plant leaf area, weight, and stalk base torque by implementing different leaf-cutting and ear-removal treatments. …”
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Treatment of blunt splenic injury in children in China by Wu Wang, Wu Wang, Haiyan Lei, Wenhan Zhang, Wenhai Li, Hongqiang Bian, Hongqiang Bian, Hongqiang Bian, Jun Yang, Jun Yang

“…The dataset included demographics, mechanism of injury, injury grade, associated injuries, therapeutic measures, and outcomes, which were subjected to statistical analysis. Factors influencing length of hospital stay and treatment regimen were also analyzed.ResultsA total of 88.5% of patients underwent NOM, with 11% requiring splenic embolization due to hemodynamic instability or arterial hemorrhage. …”
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