Tuberculosis Treatment Outcomes and Its Predictors among Tuberculosis Patients Registered at Tefera Hailu Memorial General Hospital, Sekota Town, Northeast Ethiopia: A Seven-Year R... by Habtu Debash, Jemberu Nega, Habtye Bisetegn, Gebru Tesfaw, Daniel Getacher Feleke, Hussen Ebrahim, Alemu Gedefie, Mihret Tilahun, Ousman Mohammed, Ermiyas Alemayehu, Melaku Ashagrie Belete, Abdurahaman Seid, Agumas Shibabaw

“…Data were entered, cleaned, and analyzed using SPSS version 25. Descriptive statistics and logistic regression analysis were employed. …”
Get full text

Socio-psychological distress, violence, and food insecurity in women undergoing gynecological examinations: insights from a cross-sectional study of an Italian Tertiary ClinicAJOG... by Tina Pasciuto, PhD, Francesca Moro, PhD, Drieda Zace, PhD, Lidia Borzì, MSc, Katiuscia Patrizi, MSc, Roberta Di Battista, MSc, Francesca Ciccarone, MD, Floriana Mascilini, PhD, Elena Teodorico, MD, Giulia Zinicola, MD, Maria Luisa Di Pietro, PhD, Giovanni Scambia, PhD, Antonia Carla Testa, PhD

“…Multivariable logistic regression models for predicting outcomes were performed including those parameters that were statistically significant at univariable analysis (p value <.05). …”
Get full text

Peripheral blood metabolic composite score based on peripheral blood metabolism can be used as an assessment of recurrence after surgery in patients with locally advanced gastric c... by Ning Meng, Zhiqiang Wang, Yaqi Peng, Xiaoyan Wang, Wenju Yue, Le Wang, Jingxia Lv, Jingxia Lv, Jingxia Lv, Wenqian Ma, Wenqian Ma, Wenqian Ma

“…Peripheral blood metabolic indicators, including low-density lipoprotein/high-density lipoprotein (LHR), cholesterol/high-density lipoprotein (TCHR), triglycerides/high-density lipoprotein (TGHR), and triglycerides × fasting blood glucose (TyG), were used to assess metabolic status. Multivariable regression and survival analysis were performed to assess the prognostic value of these markers. …”
Get full text

Prediction model for cytomegalovirus infection following hematopoietic stem cell transplantation in patients with β-thalassemia major by Lin Pan, Zhenbin Wei, Yanni Xie, Zhaoping Gan, Hongwen Xiao, Lianjin Liu, Lingling Shi, Zhongming Zhang, Meiqing Wu, Yinghua Chen, Yanye Liu, Xuemei Zhou, Chan Li, Chunjie Qin, Yongrong Lai, Rongrong Liu

“…Methods: Clinical data from 291 β-thalassemia major patients undergoing hematopoietic stem cell transplantation were retrospectively analyzed. Independent risk factors identified via univariate and multivariate logistic regression analyses formed the basis of a predictive nomogram. …”
Get full text

A novel prognostic model utilizing TMTV and SUVmax from 18F-FDG PET/CT for predicting overall survival in patients with extranodal NK/T- cell lymphoma by Hua Wang, Demei Feng, Yiwen Mo, Huangming Hong, Yingying Hu, Li Huang, Xiaolei Wei, Yajun Li, Haibin Huang, Runhui Zheng, Yonghua Li, Hui Zeng, Robert Peter Gale, Tian Ying, Jing Guo, Zhenshu Xu, Wei Fan, Tongyu Lin

“…Optimal cut-off values were determined using the Youden’ index. Cox regression analysis identified significant prognostic factors. …”
Get full text

Associations between red cell distribution width and in-hospital mortality in congestive heart failure patients with chronic obstructive pulmonary disease: a retrospective cohort s... by Mixia Li, Kai Zhang, Yu Shi, Tianyi Cai, Zhao Xuan Gu, Yu Han, Fang Ming Gu, Tian Qi Zhang, Min Gao, Bo Li, Dan Cui, Kexiang Liu

“…The impact of RDW at ICU admission on in-hospital mortality was analyzed through multivariable logistic regression models, generalized additive models, and subgroup analysis.ResultsWe enrolled 6,309 patients with congestive heart failure and concomitant chronic obstructive pulmonary disease, with an in-hospital mortality rate of 12.4% (783/6,309). …”
Get full text

TyG-BMI as a predictor of ischemic stroke over 10 years in middle-aged and older adults: findings from the China cardiometabolic disease and cancer cohort (4C) study by Ying Miao, Ying Miao, Ying Miao, Ying Miao, Ying Miao, Yu Wang, Yuting He, Pijun Yan, Pijun Yan, Pijun Yan, Pijun Yan, Pijun Yan, Qin Wan, Qin Wan, Qin Wan, Qin Wan, Qin Wan

“…The Log-rank test revealed a significant increase in the cumulative incidence of IS across increasing TyG-BMI quartiles (p &lt; 0.01). Furthermore, Cox regression analysis identified a significant correlation between TyG-BMI levels, as a risk factor, and the occurrence of IS. …”
Get full text

Mapping the Epidemiologic Features of Endotracheal Tube ObstructionTake-Home Points by Vimal Bhardwaj, MD, FNB(Critical Care), EDIC, Abhishek Samprathi, MD, DrNB, EDIC, Manu M.K. Varma, MD, DM, Kingshuk Saha, MSc, Ross Prager, MD, John Basmaji, MD, Nicolas Orozco, MD, Srirang Ramamoorthy, MSc, Jose Chacko, MD, EDIC, Arjun Alva, MD

“…Multivariable regression analysis showed only Ppeak (β = 1.65 [95% CI, 1.28-2.02]; P < .01), coagulopathy (β = 8.02 [95% CI, 3.26-12.79]; P < .01) and larger number of days receiving invasive mechanical ventilation (β = 0.02 [95% CI, 0.01-0.03]; P < .01) to be significant factors associated with ETB percentage. …”
Get full text

Evaluating the value of machine learning models for predicting hematoma expansion in acute spontaneous intracerebral hemorrhage based on CT imaging features of hematomas and surrou... by Tianyu Yang, Tianyu Yang, Zhen Zhao, Yan Gu, Shengkai Yang, Yonggang Zhang, Lei Li, Ting Wang, Zhongchang Miao

“…CT images were segmented using United Imaging uAI software and both imaging features and clinical characteristics were extracted. Independent risk factors were identified through univariate analysis and least absolute shrinkage and selection operator (LASSO) regression. …”
Get full text

Impact of spinal cord anomalies on defecation and quality of life in children with anorectal malformations by FAN Linxiao, FENG Wei, XIANG Chenzhu

“…The relationship between these factors and defecation function as well as quality of life was then analyzed. …”
Get full text

A polymorphism in the glucocorticoid receptor gene is associated with refractory hypotension in premature infants by Kei Ogasawara, Maki Sato, Koichi Hashimoto, Takashi Imamura, Hayato Go, Mitsuaki Hosoya

“…The following primary clinical outcomes were assessed: refractory hypotension in the acute phase and/or severe bronchopulmonary dysplasia, maximum dopamine and dobutamine doses administered, and total hydrocortisone dose administered in the first 48 h of life. Multivariate analysis with logistic regression was used to assess the association between clinical factors and refractory hypotension. …”
Get full text

Study on the electrocatalytic CO2 reduction performance of covalent organic framework materials based on machine learning by Zhang Xiangying, Wang Sitan

“…In order to accurately predict the catalytic performance of covalent organic framework materials (COFs) for electrocatalytic carbon dioxide and analyze the influencing factors affecting the catalytic effect, this study collected COFs structure data and experimental data from 44 literatures, and used machine learning methods. …”
Get full text

The Effect of Brand Image, Price, and Marketing Content on Buying Interest of Erigo Products in Surabaya by Bagas Branahda Putra Agung, Maharani Ikaningtyas

“…Data collection was carried out through the distribution of online questionnaires. The data analysis technique used was multiple linear regression to determine the effect of each independent variable on the dependent variable. …”
Get full text

The response to anti-seizure medications and the development of pharmacoresistant epilepsy in malformations of cortical development by Pu Miao, Meiping Ying, Ruotong Chen, Yuyu Yang, Yao Ding, Junming Zhu, Jianhua Feng, Jin Wang, Thandar Aung, Shuang Wang, Bo Jin

“…The clinical features of group I and group II were compared. Factors associated with PRE were analyzed. The time to development of PRE with different ASMs was assessed using Kaplan–Meier survival analysis. …”
Get full text

Investigating mortality trends and disparities in tricuspid valve disorder: a U.S. nationwide study from 1999 to 2023 by Yusra Ansari, Adarsh Raja, Sandesh Raja, Sheikh Muhammad Ebtehaj Ali, Farman Ali, Isma Noor, Amber Siddique, Saad Shakil, Abdullah, Mahnoor Asghar Keen, Bayan Zafar, Maheera Farooqi, Nabeeha Essam, Muhammad Sami Khan, Muhammad Hamza Shuja, Biruk Demisse Ayalew

“…Joinpoint regression analysis was conducted to assess annual percent changes (APCs) in mortality rates. …”
Get full text

Efficacy and safety outcomes of PD-1/PD-L1 inhibitors in recurrent cholangiocarcinoma: a real-world, multicenter and retrospective study by Lihui Lin, Yansong Lin, Wei Chen, Xia Yang, Xianwen Guo, Yanqin Wu, Xiaoyu Yin, Zhen Ding, Jingping Yun

“…Cox regression analyses were conducted to assess prognostic factors associated with the efficacy of PD-1/PD-L1 inhibitors in recurrent CCA. …”
Get full text

The Chain Mediation Role of Self-Efficacy, Health Literacy, and Physical Exercise in the Relationship Between Internet Use and Older Adults’ Health: Cross-Sectional Questionnaire S... by Weizhen Liao, Chengyu Ma, Xiqiao Liu, Ziwei Sun

“…However, the role of individual factors such as self-efficacy, health literacy, and physical exercise in the chain of influence between internet use and the health of older adults is unclear. …”
Get full text

Construction and validation of risk prediction models for different subtypes of retinal vein occlusion by Chunlan Liang, Lian Liu, Wenjuan Yu, Qi Shi, Jiang Zheng, Jun Lyu, Jingxiang Zhong

“…Predictors encompassed clinical histories and laboratory indices. Multivariate regression identified independent risk factors, and model performance was evaluated using the area under the receiver operating characteristic curve (AUC), calibration plots, and decision curve analysis (DCA). …”
Get full text

The predictive value of mean platelet volume to platelet count ratio combined with APACHEⅡs for short-term prognosis of patients with acute kidney injury treated by continuous rena... by TANG Ying-ying, NI Xun, Lv Jian-nong

“…Objective To investigate the predictive value of mean platelet volume(MPV)to platelet count(PLT)ratio(MPR)combined with acute physiology and chronic health evaluation Ⅱ(APACHE Ⅱ)scoring for the short-term prognosis of patients with acute renal injury(AKI)treated with continuous renal replacement therapy(CRRT).Methods A total of 138 AKI patients who received CRRT in our hospital from January 2016 to October 2019 were retrospectively included.According to their survival conditions at discharge,they were divided into survival group(n=80)and death group(n=58).The value of MPR,APACHE Ⅱ score and their combination for predicting the death of AKI patients was analyzed by ROC curve.The independent risk factors for poor prognosis were evaluated by multivariate logistic regression analysis.Results(1)MPV,MPR and APACHE Ⅱ scores of patients in the death group were significantly higher than those in the survival group[(11.9±1.1)fl vs.(11.0±1.1)fl,P<0.01;0.11(0.09,0.14)vs.0.08(0.06,0.11),P<0.01;(25.0±3.5)score vs.(19.5±3.4)score,P<0.01].PLT count of patients in death group was significantly lower than that of survival group[(108.9±28.0)×10~9/L vs.(146.8±41.4)×10~9/L,P<0.01].(2)The cutoff values of MPR,APACHE Ⅱ score and the combination to predict the death of AKI patients were 0.08,24 points and 0.54,respectively.The AUC of death in AKI patients predicted by MPR combined with APACHE Ⅱ was significantly higher than that of MPR and APACHE Ⅱ alone[0.892(0.828-0.938)vs.0.737(0.656-0.809),P<0.01;0.892(0.828-0.938)vs.0.838(0.766-0.896),P<0.05].(3)APACHE Ⅱ score(≥24),MPR combined with APACHE Ⅱ score(APACHE Ⅱ score≥24,and MPR≥0.08),diuretics administration were the independent risk factors for poor prognosis in AKI patients[HR(95%CI):2.311(1.034-5.166),3.533(1.541-8.098),34.816(7.475-162.149),all P< 0.05].Conclusions MPR combined with APACHE Ⅱ score can well predict the short-term prognosis of AKI patients treated with CRRT.…”
Get full text

One-step ahead: evaluating the efficacy of single-visit rabies pre-exposure prophylaxis against conventional multi-visit protocol: a randomized non-inferiority clinical trial by Aman Dev Singh, Simmi Oberoi, Rohit Batish, Kanwardeep Singh, Maninder Kaur, Shailpreet Kaur Sidhu, Avneet Kaur, Prabhasees Singh

“…Both groups showed significant increases in antibody seroconversion (OD)titres from baseline (p = 0.0038 for Group A, p < 0.0001 for Group B). Regression analysis indicated no significant influence of demographic factors on antibody levels. …”
Get full text