Advances and challenges in plant spatial metabolomics research(植物空间代谢组学研究的进展与挑战) by 张韵千(ZHANG Yunqian), 蔡圣冠(CAI Shengguan)

“…In addition, this paper conducted an in-depth analysis of the technical challenges currently faced by spatial metabolomics, and explored improvement strategies, aiming to provide the theoretical support and practical reference for advancing the development of spatial metabolomics in plants. . …”
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Investigating the vertical and lateral heterogeneity in an Iranian carbonate reservoir using advanced petrophysical logs, petrographic data and image processing techniques by Saeed Yarmohammadi, Abdolrahim Javaherian, Mohammad Sharifi, Mohammad Reza Saberi, Hadi Mahdavi Basir

“…The models developed through this workflow enhance decision-making in reservoir characterization and offer practical applications for field studies. Despite limitations like imaging resolution and data availability, this approach remains integral to advancing the understanding of heterogeneity and guiding further improvements. …”
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A study of traveling wave solutions and modulation instability in the (3+1)-dimensional Sakovich equation employing advanced analytical techniques by Jamshad Ahmad, Maham Hameed, Zulaikha Mustafa, Farah Pervaiz, Muhammad Nadeem, Yahya Alsayaad

“…Not only does this thorough study advance theoretical insight but also increase practical applications in areas like optical fiber communication and engineering. …”
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Assessment of Factors Limiting Advanced Technology Adoption in Maize Cultivation in Uganda: A Case Study of Kabale District South Western Uganda. by Asiimwe, Moses

“…The role of policy interventions in facilitating the uptake of advanced technology practices is also a critical aspect of this study. …”
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The Development of a Forceps-Adaptable Pressure Device for Instrumental Delivery: A Proof-of-Concept Study for Clinical and Educational Applications by Mathieu Hivert, Cyril Bengler, Julien De Jonckheere, Franck Gaultier, Marie Pécout, Olivier Mayeur, Chrystèle Rubod

“…Conclusions: The developed device represents a significant advancement, as no existing system measures the pressure exerted by forceps blades on the fetal head. …”
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Technical Advances of Temporary Facilities for the Failure Prevention of Large-Span Cantilever Casting Construction of Mountainous Concrete Box-Type Arch Bridges by HongJu Han, JiPing Guo, JiJin Zhang, Yuan Sun

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Enhancing emergency response efficiency through advanced urban logistics: The role of driver psychophysiology and vehicle dynamics in mitigating socio-economic impacts by Yurii Davidich, Dávid Földes, Andrii Galkin

“…The outcomes of this study have practical implications for policy formulation and the operational structuring of emergency units, emphasising the need for strategic planning that incorporates driver welfare and advanced logistics management. …”
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Optimizing Pharmaceutical Inventory and Investment Strategies During Pandemics: A Dynamic Approach Integrating Environmental Emission Rates and Advanced Optimization Algorithms by Vinita Dwivedi, Mamta Keswani, Uttam Kumar Khedlekar, Lalji Kumar

“…Theoretical analysis and numerical experiments under a fuzzy learning environment provide a robust foundation for the model. Sensitivity analysis offers practical insights, guiding decision-makers in adapting strategies to real-world challenges. …”
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Cost-effectiveness analysis of penpulimab combined with paclitaxel and carboplatin as first-line treatment for advanced squamous non-small cell lung cancer by Xiaoyan You, Xiaoyan You, Jiali Qin, Jiali Qin, Xiaomei Wang, Xiaomei Wang, Xianying Wang

“…The immaturity of the OS data increased the extrapolation uncertainty, which could potentially alter the economic conclusions.ConclusionPenpulimab, in combination with paclitaxel and carboplatin, demonstrates a cost-effectiveness advantage over placebo as a first-line treatment for advanced or metastatic squamous NSCLC in China, provided that long-term survival benefits align with extrapolations from the base case model. …”
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Navigating perinatal mental health integration in maternal and child health services: progress and priorities for research and practices in Pakistan by Waqas Hameed, Atif Rahman

“…We synthesise perinatal mental health (PMH) evidence and provide recommendations for future research and practices in Pakistan. …”
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Synergistic Integration of LQR Control and PSO Optimization for Advanced Active Suspension Systems Utilizing Electro-Hydraulic Actuators and Electro-Servo Valves by Trong Tu

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Thoughts and Practices on the Development of Forensic Medicine Discipline in the Perspective of Building a Regional High-Level Medical University by CHEN Guang, WANG Rong-shuai, SU Li, ZHANG Yue, LIU Xue-xia, FANG Shi-yong, LIU Zhan-zhan, XU Ya-jun, XU Xiang

“…Combined with the experiences of carrying out forensic medicine education in our college, this paper supplies our thoughts and practices on improving the discipline system, enhancing the ability to serve society, perfecting the talent cultivation model and promoting forensic culture, to provide reference and inspiration for the development of forensic medicine in other universities, jointly promote the advancement of forensic medicine in China to a new stage, and contribute the wisdom and strength of forensic medical experts to the construction of a law-based China, a safe China and a healthy China.…”
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Enhancing Teacher Creativity through Educational Game Tools at TK Negeri Pembina, Kediri: A Practical Approach by Intan Prastihastari Wijaya

“…The training program encompasses theoretical teachings, interactive discussions, and practical exercises in designing and implementing educational games. …”
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Anticoagulant Therapy as a Tool for the Prevention of Cognitive Impairment Associated with Atrial Fibrillation by O. D. Ostroumova, A. I. Kochetkov, S. P. Korchagina, T. M. Ostroumova, M. S. Chernyaeva, A. A. Kirichenko

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Pharmacoeconomic efficacy of atesolizumab compared with other PD-1 inhibitors in patients with advanced non-small cell lung cancer after chemotherapy by S. K. Zyryanov, I. N. Diyakov

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Lower respiratory tract microbiome dysbiosis impairs clinical responses to immune checkpoint blockade in advanced non‐small‐cell lung cancer by Yong Zhang, Xiang‐Xiang Chen, Ruo Chen, Ling Li, Qing Ju, Dan Qiu, Yuan Wang, Peng‐Yu Jing, Ning Chang, Min Wang, Jian Zhang, Zhi‐Nan Chen, Ke Wang

“…Conclusions This study provided a microecological landscape of the lower respiratory tract with advanced NSCLC to ICI interventions and presented a multidimensional perspective with favoured outcomes that may improve the predictive capacity of the localized microbiome in clinical practices. …”
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Codeless Development of a Customized SMILE Nomogram Using a Large Language Model: A Practical Framework for Clinicians by Hye Won Jun, Sun Young Ryu, Tae Keun Yoo

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Participatory approaches for developing a practical handbook integrating health information for supporting individuals with mild cognitive impairment and their families by Yujiro Kuroda, Aya Goto, Taiki Sugimoto, Kosuke Fujita, Kazuaki Uchida, Nanae Matsumoto, Hiroyuki Shimada, Rei Ohtsuka, Minoru Yamada, Yoshinori Fujiwara, Aya Seike, Madoka Hattori, Gabin Ito, Hidenori Arai, Takashi Sakurai

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Implementation and effectiveness of advance care planning in hospitalized older adults with chronic heart failure: a mixed-methods systematic review and meta-analysis by Li Chen, Li Chen, Yuqiu Cheng, Yuqiu Cheng, Jun Qu, Zhangyi Wang

“…Meta-aggregation showed that the ACP intervention has a positive impact on participants, promotes their knowledge and understanding, and makes them share their decision-making with their families.ConclusionACP is a promising and feasible intervention that can help older adults with CHF accurately understand ACP and express their wishes timely. This study provides insights and empirical evidence to improve ACP, and valuable guidance and reference for future clinical practice.Systematic review registrationhttps://www.crd.york.ac.uk/PROSPERO/, PROSPERO, identifier: CRD42024580814.…”
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