Ultrasound therapy inhibits knee osteoarthritis progression in rabbits by activating the PPARs pathway: a pilot study by Qinglu Luo, Ruike Zhang, Zhizhao Liang, Yanhua Wen, Yi Zhang, Jinyi Liu, Zhongmin Ouyang, Hongbo Wu

“…The mechanism by which US therapy inhibits KOA was studied using GW6471 (PPAR-α antagonist) and Mifobate (PPAR-γ antagonist).Results MRI revealed that US therapy slowed cartilage thinning and improved cartilage structure in the KOA model. Concurrently, US therapy effectively reduced chondrocyte damage and degradation via modulating mRNA and protein levels of PPARs-related signaling pathways in both cartilage and synovial tissues. …”
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Ethnomedicinal documentation of plants used for gastrointestinal disorders in Sahiwal District Pakistan by Nidaa Harun, Muhammad Waheed, Syeda Sitwat Rubab, Madeeha Arshad, Shiekh Marifatul Haq, Fahim Arshad, Syeda Maryam Hussain, Imrana Bukhari, Muhammad Shoaib, Kaneez Fatima, Rainer W. Bussmann, Abeer Hashem, Adel M. Al-Saif, Elsayed Fathi Abd-Allah

“…The interviews of 125 respondents were conducted during August 2021–January 2022 via a semi-structured questionnaire. Floristic analysis yielded a total of 73 plant species in 65 genera and 35 families. …”
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Finding New Hot Subdwarf Stars in SDSS Images by Jiangchuan Zhang, Yude Bu, Huili Wu, Yuhang Zhang, Shanshan Li, Zhenxin Lei, Zhenping Yi, Xiaoming Kong, Meng Liu

“…Hot subdwarf stars, located at the end of the blue horizontal branch, have a burning helium core, and are crucial for studying stellar structure. Currently, the number of known hot subdwarf star is relatively small. …”
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A Compact Shared-Aperture Antenna With 2-Transmit and 2-Receive Highly-Isolated Ports for Full-Duplex MIMO Systems by Junhui Rao, Zhaoyang Ming, Jichen Zhang, Zan Li, Chi-Yuk Chiu, Ross Murch

“…A novel “inverted mushroom” (IMR) structure, composed of a metallic pillar fence connecting two layers of optimized metal tiles, is introduced at the antenna’s center to suppress the Tx ports MC and ensure effective radiation for Rx ports. …”
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Development of a Method and a Scheme for the Use of a Live Recombinant Vaccine "GamLPV". Safety and Tolerability of Double Intranasal Vaccination of Healthy Adult Volunteers by G. I. Karataev, A. Yu. Medkova, E. G. Semin, L. N. Sinyashina, R. A. Sioundioukova, S. V. Kulikov, N. A. Snegireva, I. N. Chernishova, M. V. Gavrilova, K. K. Bushkova, A. A. Lidzhieva, L. V. Kolobukhina, I. S. Kruzhkova, L. N. Merkulova, M. G. Rusanova, M. V. Bazarova, N. A. Antipyat, S. V. Smetanina, E. A. Smolyarchuk, I. N. Dyakov

“…The choice of the scheme and method of administration of the drug is justified. The serological structure of the population of adults aged 18–40 years living in Moscow and the Moscow region is characterized.Aim. …”
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Strain and contact-dependent metabolomic reprogramming reveals distinct interaction strategies between Laccaria bicolor and Trichoderma by Prasath Balaji Sivaprakasam Padmanaban, Pia Stange, Baris Weber, Andrea Ghirardo, Karin Pritsch, Tanja Karl, J. Philipp Benz, Maaria Rosenkranz, Jörg-Peter Schnitzler

“…Interactions between the mycoparasitic Trichoderma spp. and beneficial ectomycorrhizal fungi such as Laccaria bicolor (Hydnangiaceae, Basidiomycota) can influence the structure of fungal communities and plant symbioses. …”
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Determinants of indiscriminate antimicrobial use in commercial chicken farms in Bangladesh and their impact on food safety and public health by Mehedi Hasan, Tiasha Ali, A. K. M. Dawlat Khan, Monjurul Islam, Arif Khan, Abu Sayeed, Zulqarnine Ibne Noman, Abdullah Al Mamun, Shariful Islam, Mohammad Mahmudul Hassasn, Cameron E. F. Clark, Tahmina Shirin, Ariful Islam

“…Data were collected using in-person interviews with a pre-tested semi-structured questionnaire. Statistical analyses were performed, including descriptive statistics to understand farmer demographics and AMU practices, a Chi-square test to evaluate farmers’ knowledge, attitudes and practices (KAP), and logistic regression analysis to determine the factors associated with AMU. …”
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Polymorphisms in SAA alter intrarenal amyloid distribution of AA amyloidosis in cats by Natsumi Kobayashi, Masahiro Kaneda, Mitsuhiro Ikeda, Hirotaka Kondo, Susumu Iwaide, Yoshiyuki Itoh, Miki Hisada, Yuka Kato, Niki Sedghi Masoud, Kohji Nomura, Machie Tsuneyasu, Tomoko Akamine, Tomoaki Murakami

“…Moreover, this study is the first report of such a complex pattern of amyloid deposition in the organ of the same individual, emphasizing that the primary structure of the amyloid precursor protein determines amyloid distribution.…”
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Machine learning and response surface methodology forecasting comparison for improved spray dry scrubber performance with brine sludge-derived sorbent by B.J. Chepkonga, L. Koech, R.S. Makomere, H.L. Rutto

“…The computational framework utilized experimental variables structured by CCD software as input metadata. Model performance was evaluated through generalization and accuracy measurements, including the coefficient of determination (R²), root mean square error (RMSE), mean square error (MSE), and mean squared logarithmic error (MSLE). …”
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Vericiguat improves cardiac remodelling and function in rats with doxorubicin‐induced cardiomyopathy by Wen Chen, Ying Wu, Wei Li, Meiyan Song, Kaizu Xu, Meifang Wu, Liming Lin

“…In this study, we investigated the effects of vericiguat on cardiac structure and function in rats with DIC as well as their potential mechanisms of action. …”
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Improving aboveground biomass density mapping of arid and semi-arid vegetation by combining GEDI LiDAR, Sentinel-1/2 imagery and field data by Luis A. Hernández-Martínez, Juan Manuel Dupuy-Rada, Alfonso Medel-Narváez, Carlos Portillo-Quintero, José Luis Hernández-Stefanoni

“…Moreover, uncertainties remain about the type of GEDI footprint that best penetrates the canopy and yields accurate vegetation structure metrics. This study estimates forest biomass of arid and semi-arid zones in two stages. …”
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Postoperative functional training program for vascularised Iliac flap donor site in jaw defect reconstruction based on the Delphi method by Li Li, Qian He, Na Zhou, Zhaoxia Zhang, Xiaoming Lv, Jie Zhang

“…., restrictions on flexion < 90°, and bans on squatting or cross-legged sitting). PFT is structured into six progressive phases, with exercise intensity tailored to assessment outcomes. …”
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Validation of the Spanish Version of the Headache Impact Test (HIT‐6) in Patients With Episodic Migraine by Yaiza Colorado‐Martín, Daniel Pecos‐Martín, Nerea deMiguel‐Hernando, Rubén Cámara‐Calmaestra, Daniel Rodríguez‐Almagro, Alejandro Ferragut‐Garcías, Eduardo Castro‐Martín, Alexander Achalandabaso‐Ochoa

“…Results The principal component analysis revealed a two‐component structure. The overall HIT‐6 scale demonstrated strong test‐retest reliability ([ICC = 0.89; 95% CI = 0.83–0.92]), with high reliability for the indirect subscale [(ICC = 0.87; 95% CI = 0.81–0.91)] and excellent reliability for the direct subscale [(ICC = 0.90; 95% CI = 0.85–0.93)]. …”
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Straw retention drives microbial community succession to improve soil C/N cycling: insights from a multi-year rice-based system by Shu Jia, Yue-Dong Li, Hang Qu, Bo Li, Ying-hua Juan, Yue-hua Xing, Yan Liu, Hong-jing Bao, Wen-tao Sun

“…The present study aimed to elucidate the dynamic responses of soil microbial community structure and function to rice straw retention using a multi-year field experiment. …”
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Hedgehog inhibitor in the treatment of basal cell skin cancer: case report by Sh. I. Musin, N. А. Sharafutdinova, A. V. Sultanbaev, S. V. Osokin, B. A. Ibragimov, K. V. Menshikov, R. T. Ayupov

“…Background. In the structure of malignant neoplasms, basal cell skin cancer (BCC) occupies a leading position. …”
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Development and validation of the internet gaming disorder scale-9 short form Japanese version for children for early screening in elementary school children by Azusa Ogiso, Takeshi Inoue, Tasuku Kitajima, Tasuku Kitajima, Yuta Ujiie, Yuji Oto, Ryoichi Sakuta

“…Confirmatory factor analysis indicated a unidimensional structure with acceptable model fit indices (GFI = 0.942, CFI = 0.931, RMSEA = 0.085). …”
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Review of the Epidemiological Situation on Ixodidae Tick-Borne Borrelioses in the Russian Federation in 2010–2024 and Forecast for 2025 by S. A. Rudakova, O. E. Teslova, N. E. Mutalinova, N. V. Rudakov, N. A. Pen’evskaya, Yu. F. Kuz’menko, D. V. Trankvilevsky

“…Effective control of the ITBB epidemic situation is possible provided that the volume of preventive measures is maintained, and zoological-entomological monitoring of the activity and structure of natural foci is strengthened.…”
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Facilitators and barriers to participation of patients with treatment resistant depression in a randomised controlled trial of two forms of personalised magnetic resonance imaging... by Clement Boutry, Lucy Webster, Louise Thomson, Delilah Harding, Isabel Reid, Peter Bates, John Gledhill, Rebecca McNaughton, Jane Eastham, Joanne Ooi, Andy Willis, Sonal Marner, Richard Morriss

“…Methods Nineteen participants from the BRIGhTMIND RCT of two forms of MRI personalised TMS, completed semi-structured interviews exploring the reasons behind the uptake and experience of TMS. …”
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Effects of different protein and lipid levels on the growth performance, intestinal health and intestinal microflora of pikeperch (Sander lucioperca) juvenile by Jie Zhao, Yang Liu, Zhipeng Sun, Liansheng Wang, Ze Fan, Tianqi Liu, Kexin Zhang, Yihua Xu, Xianhu Zheng, Cuiyun Lu

“…When the protein level of the feed was 51 % and the lipid level was 18 %, the growth performance of juvenile pikeperch was the best, and there was no obvious tissue damage or inflammatory response. The structure of the intestinal microflora was also relatively stable, indicating that the optimal protein and lipid levels for juvenile pikeperch were 51 % and 18 %, respectively.…”
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Development prospects of “Internet + medical and health services” in Shandong: application status and public acceptance by YingJie Gao, YaQiong Wang, XiaoLin Yan, GuanNan Sun, Cong Chen, Xiang Gao

“…BackgroundThe integration of Internet technology into healthcare has led to the birth of the “Internet + medical and health services” model-a transformative approach to improving accessibility and efficiency in healthcare delivery.ObjectiveThis study aims to assess the current status, challenges, and user perceptions of the “Internet + medical and health” services platform among individuals in Shandong, China.MethodsThe cross-sectional survey was conducted between September 2023 and October 2023 on patients from public medical institutions in Shandong Province. A structured questionnaire was employed to gather information on the general characteristics of the respondents and information about platform usage and user experiences.ResultsOf the 400 distributed questionnaires, 353 were valid. …”
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