Predictive modeling of ADME properties using M-polynomial based topological indices for biocompatible polysaccharides by W. Eltayeb Ahmed, Muhammad Naeem, Muhammad Kamran Siddiqui, Mohamed Abubakar Fiidow

“…Abstract Dextran and chitosan, two natural polysaccharides, are recognized for their biocompatibility, biodegradability, and structural adaptability. Dextran, composed of glucose units with predominant $$\alpha$$ -(1 $$\rightarrow$$ 6) linkages, exhibits flexible conformations influenced by branching and molecular weight. …”
Get full text

全基因组关联分析标准化流程的构建与扩展应用(Development and Extended Applications of Standardized Processes for Genome-Wide Association Studies) by 许喆1，2，石延枫1，2，张杰1，2，姜明慧1，2，刘阳1，2，李昊1，2，3，廖晓凌4，程丝1，2，3(XU Zhe1,2, SHI Yanfeng1,2, ZHANG Jie1,2, JIANG Minghui1,2, LIU Yang1,2, LI Hao1,2,3, LIAO Xiaoling4, CHENG Si1,2,3)

“…Association analysis module: using software such as PLINK, SAIGE, and Regenie, GWAS was performed utilizing generalized linear models and generalized linear mixed models. …”
Get full text

High-Frequency Ultrasonography As An Innovative Diagnostic Method in Dermatology by Aneta Rasińska, Piotr Rzyczniok, Anna Rzyczniok, Weronika Rasińska, Justyna Jachimczak, Filip Grydź, Joanna Filipow, Anna Rebizak, Paulina Bala, Aneta Rostkowska, Sebastian Kupisiak, Natalia Pasierb, Justyna Matusik, Mateusz Kopczyński

“…The physical conditions of  HFU make it possible  to estimate the parameters of the skin structure, such as thickness and echogenicity (a feature related to the center) of its layers in relation to the surrounding tissues. …”
Get full text

Short-term PM1 exposure and sleep duration: a nationwide study using consumer-grade wearable devices by Jiajun Liu, Mintao Su, Junxiong Ma, Qinfeng Zhou, Hanxu Shi, Yujie Shi, Shuyu Huang, Yuchuan Tang, Peining Zhou, Kunyao Yu, Rui Su, Rui Zhou, Jing Wei, Jing Ma, Zhenyu Zhang

“…Although individual sleep duration changes appear modest, the cumulative impact of PM _1 on sleep structure, especially in vulnerable populations, poses significant public health risks in physiological restoration. …”
Get full text

Association between neutrophil-percentage-to-albumin ratio and periodontitis: insights from a population-based study by Ziyang Zheng, Ziyang Zheng, Ziyang Zheng, Xinyu Xie, Xinyu Xie, Xinyu Xie, Lan Wang, Lan Wang, Lan Wang, Mingzhang Xu, Mingzhang Xu, Mingzhang Xu, Jiaqi He, Jiaqi He, Yunyi Deng, Yunyi Deng, Yunyi Deng, Ke Yu, Ke Yu, Ke Yu

“…BackgroundPeriodontal diseases, characterized by the loss of tooth-supporting structures, are highly prevalent in the general population. …”
Get full text

Improvement of the perovskite photodiodes performance via advanced interface engineering with polymer dielectric by Andrey P. Morozov, Lev O. Luchnikov, Sergey Yu. Yurchuk, Artur R. Ishteev, Pavel A. Gostishchev, Sergey I. Didenko, Nikita S. Saratovsky, Dmitry O. Balakirev, Ivan V. Dyadishchev, Andrey A. Romanov, Ekaterina A. Ilicheva, Anton A. Vasilev, Sergey S. Kozlov, Dmitry S. Muratov, Yuriy N. Luponosov, Danila S. Saranin

“…The integration of P(VDF-TrFE) into the perovskite film didn’t affect the morphology and crystal structure, but significantly changed the charge transport and device performance. …”
Get full text

Experimental and machine learning-driven assessment of IS 2062 steel under double-base propellant combustion conditions by Hari Singh, Dola Sundeep, C. Chandrasekhara Sastry, Eswaramoorthy K Varadharaj

“…Conversely, Test-07 exceeded 355–372 ksc with burn rates surpassing 41 mm/s, exhibiting erosive burning and accelerated steel erosion.Material characterization techniques, including X-ray Diffraction (XRD), Fourier Transform Infrared Spectroscopy (FTIR), Raman Spectroscopy, Field Emission Scanning Electron Microscopy (FESEM), and Energy Dispersive Spectroscopy (EDS), revealed significant oxidation, scale formation, and localized surface degradation, in high-temperature regions around 2500 Kelvinat the nozzle throat inducing structural changes. To enhance predictive accuracy, machine learning models Linear Regression, Random Forest Regression, Support Vector Machines (SVM), K-Means Clustering, and Artificial Neural Networks (ANN) were employed to analyze combustion-induced degradation trends, confirming Test-06 as the optimal balance of stability and high performance. …”
Get full text

All-on-chip reconfigurable generation of scalar and vectorial orbital angular momentum beams by Weike Zhao, Xiaolin Yi, Jieshan Huang, Ruoran Liu, Jianwei Wang, Yaocheng Shi, Yungui Ma, Andrew Forbes, Daoxin Dai

“…Abstract Structured light carrying angular momentum, such as spin angular momentum (SAM) and orbital angular momentum (OAM), has been at the core of new science and applications, driving the need for compact on-chip sources. …”
Get full text

Clinical analysis of vitrectomy combined with dexamethasone intraveal implant in the treatment of epiretinal membrane by WU Kunfang, GUO Meimei, LI Xiang, WANG Dingding

“…Both surgical methods can improve the structure, function, and microcirculation disorders in the macular area. …”
Get full text

Model Optimization for High-Yield Biocrude in Co-Hydrothermal Liquefaction of Municipal Sludge by Botian HAO, Yunfei DIAO, Ya WEI, Donghai XU

“…The RSM established a predictive model based on a second-order polynomial equation, achieving an R2 value of 0.9833 and demonstrating excellent linear fitting capability. In contrast, the ANN employed a three-layer topological structure (3-node input layer, 10-node hidden layer, and 1-node output layer). …”
Get full text

Isolation and identification of an alginate lyase-producing marine bacterium strain and its enzymological characteristics by TANG Haiqing, OU Changrong, ZHENG Xiaodong

“…Alginate polysaccharide produced by marine brown algae or certain Gram-negative bacteria is a linear anionic binary copolymer of β-D-mannuronic acid (M) and α-L-guluronic acid (G) residues. …”
Get full text

Climate Change and Its Impacts on the Planting Regionalization of Potato in Gansu Province, China by Yulan Lu, Junying Han, Guang Li, Zhengang Yan, Lixia Dong, Zhigang Nie, Qiang Liu

“…The findings of this study can provide a scientific foundation for optimizing and adjusting the potato planting structure, considering the backdrop of climate change. …”
Get full text

Effects of nitrogen levels on soil respiration of sympodial bamboo plantation and factor analysis by LI Weicheng, WANG Shuguang, SHENG Haiyan, ZHENG Youmiao, WANG Shudong, ZHONG Zheke

“…Subsequently, what will happen to the soil structure and how to balance soil nutrient environment in the situation of chemical fertilizer abuse?…”
Get full text

INFLUENCE OF MICROSTRUCTURED COLLAGEN HYDROGEL ON PANCREATIC ISLET CELL CULTURES by L. A. Kirsanova, N. V. Baranova, G. N. Bubentsova, G. N. Skaletskaya, N. V. Perova, V. I. Sevastianov, N. N. Skaletskiy

“…The presence of the microstructured collagen hydrogel matrix during the incubation of floating islet cell cultures promoted long-term preservation of the structural integrity and hormonal activity. Simultaneously the formation of cultures of pancreatic progenitor cells (islet cells precursors) was observed. …”
Get full text

Assessing brain morphological correlates of premenstrual symptoms in young healthy females by Sara B. Marjanovic, Madelene Christin Holm Bukhari, Rikka Kjelkenes, Irene Voldsbekk, Claudia Barth, Lars T. Westlye

“…Premenstrual symptoms have been partly attributed to the brain's sensitivity to menstrual cycle-related hormonal fluctuations, which may be modulated by individual differences in the structural characteristics of the brain. In a population-based sample of 292 non-pregnant females aged 23–43 years, we tested for associations between self-reported premenstrual symptom load and T1-weighted MRI based brain measures of cortical thickness, volume, and surface area as well as subcortical volumes, not controlling for menstrual cycle phase. …”
Get full text

Strike-slip kinematics from crustal to outcrop-scale: the impact of material properties on analogue modelling by L. Massaro, J. Adam, E. Jonade, S. Negrão, Y. Yamada, Y. Yamada

“…<p>Strike-slip fault zones commonly display complex kinematics and 3D geometries, with high structural variability along strike and with depth. …”
Get full text

Circular RNA vaccines: Pioneering the next-gen cancer immunotherapy by Uddalak Das, Soupayan Banerjee, Meghna Sarkar, Fathah Muhammad L, Tanveen Kaur Soni, Madhumita Saha, Gayatri Pradhan, Bhaskarjyaa Chatterjee

“…This review delved into the fundamental principles underlying circRNA biology, highlighting their unique structural advantages and translational potential. We examined recent advancements in circRNA vaccine design, focusing on their application in oncology. …”
Get full text

Association Between Shift Working and Brain Morphometric Changes in Workers: A Voxel-wise ComparisonKey Messages by Joon Yul Choi, Sungmin Kim, Yongho Lee, Dohyeon Kim, Wanhyung Lee

“…To investigate the association of structural changes between shift workers and non-shift workers, a general linear model and threshold-free cluster enhancement were used with covariates, including total intracranial volume, age, and sex. …”
Get full text

Role of Oxygen Concentration in Reactive Sputtering of RuO₂ Thin Films: Tuning Surface Chemistry for Enhanced Electrocatalytic Performance by Swapnil Nalawade, Ebenezer Vondee, Mengxin Liu, Ikenna Chris-Okoro, Sheilah Cherono, Dhananjay Kumar, Shyam Aravamudhan

“…The impact of Ar/O₂ ratios on the structural, chemical, and optical properties of sputtered RuO₂ films is systematically investigated. …”
Get full text

Lutetium Copper@Hexagonal Boron Nitride Nanocomposite Electrode System for Sensing and Signalling Ciprofloxacin by Collen Nepfumbada, Prof. Bhekie B. Mamba, Prof. Bart M. Bartlett, Prof. Jorge F. Fernández‐Sánchez, Prof. Usisipho Feleni

“…A simple hydrothermal method was used to synthesize the nanocomposite. The structural and morphological characteristics of the as‐prepared nanocomposite were investigated using various analytical techniques such as Fourier transform infrared spectroscopy (FTIR), X‐ray diffraction (XRD), scanning electron microscopy (SEM), and X‐ray photoelectron spectroscopy (XPS). …”
Get full text