Turbulent Transport Efficiency of Momentum and Sscalar over Forest Canopy in Southern Sichuan by Yi DING, Yu ZHANG, Demin FAN, Youqi SU, Qian ZHANG, Yanqi WANG, Yanqi WANG

“…The turbulent transport characteristics of momentum and scalar over the canopy were studied by using the three levels （20 m， 38 m and 56 m） turbulence data measured at the 60m forest micro meteorological tower in southern Sichuan from May 1 to June 30， 2021.Coherent structure is the main form of turbulent motion， which is composed of updraft （ejection） and downdraft （sweep）.In this paper， the quadrant analysis method is used to analyze the boundary of the roughness sublayer， roughness sublayer and constant flux layer above the forest canopy and the ejection-sweep motion characteristics of the constant flux layer， including the difference of ejection and sweep contribution to flux， the difference between momentum and scalar transport， and the difference between different scalar （T， q， CO2） transport.The results show that under unstable and stable conditions， the ejection dominates the scalar transport at all three levels， while the sweep is the main eddy current motion for scalar transport above the roughness sublayer under neutral conditions.For the momentum flux， under unstable conditions， the ejection dominates at all three levels.Under stable conditions， the ejection dominates at the roughness sublayer and the constant flux layer， while at the boundary of the roughness sublayer and the constant flux layer， the effect of the sweep is greater than that of the ejection.Under neutral conditions， the flux contribution of the sweep is greater than that of the ejection except for the roughness sublayer.The third-order cumulant expansion method （CEM） can more accurately express the flux contribution caused by ejection and sweep， while the incomplete cumulant expansion method （ICEM） is poor in simulating the temperature at the boundary of roughness sublayer and constant flux layer.Through the calculation of transmission efficiency， the difference between momentum and scalar transmission is further quantified.The turbulent transfer efficiency of momentum decreases with increasing instability， while the heat transfer efficiency is the opposite.Atmospheric stability is an important factor controlling momentum and scalar transfer， and the transfer efficiency of water vapor is less affected by atmospheric stability.Under the condition of strong instability， the heat transfer efficiency is more effective than other scalar transfer.…”
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Novel Potent and Selective Dopamine D4 Receptor Piperidine Antagonists as Potential Alternatives for the Treatment of Glioblastoma by Federica Matteucci, Pegi Pavletić, Alessandro Bonifazi, Rian Garland, Hideaki Yano, Consuelo Amantini, Laura Zeppa, Emanuela Sabato, Giulio Vistoli, Valerio Mammoli, Loredana Cappellacci, Fabio Del Bello, Gianfabio Giorgioni, Riccardo Petrelli, Alessia Piergentili, Wilma Quaglia, Alessandro Piergentili

“…<b>Results</b>: Radioligand binding results highlighted that the derivatives bearing a terminal butyl chain showed structure–activity relationships different from those with a benzyl terminal. …”
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Chitosan nanocomposite containing rotenoids: an alternative bioinsecticidal approach for the management of Aedes aegypti by Maria A. A. Bertonceli, Vitor D. C. Cristo, Ivo J. Vieira, Francisco J. A. Lemos, Arnoldo R. Façanha, Raimundo Braz-Filho, Gustavo V. T. Batista, Luis G. M. Basso, Sérgio H. Seabra, Thalya S. R. Nogueira, Felipe F. Moreira, Arícia L. E. M. Assis, Antônia E. A. Oliveira, Kátia V. S. Fernandes

“…Importantly, empty nanoparticles exhibited no adverse effects on larval survival, which is attributed to the biocompatibility and nontoxic nature of chitosan, a biodegradable polysaccharide structurally related to the insect exoskeleton and widely recognized for its environmental safety. …”
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hpCasMINI: An engineered hypercompact CRISPR-Cas12f system with boosted gene editing activity by Shufeng Ma, Kaitong Liao, Kechen Chen, Tong Cheng, Xiaofeng Yang, Peihan Chen, Sijie Li, Mengrao Li, Xin Zhang, Yanqun Zhang, Tao Huang, Xiaobo Wang, Lanfeng Wang, Ying Lin, Zhili Rong

“…Here we introduce an engineered compact CRISPR-Cas12f (hpCasMINI, 554 aa), with hyper editing efficiency in mammalian cells via adding an α-helix structure to the N-terminus of an Un1Cas12f1 variant CasMINI (529 aa). …”
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CD147-high extracellular vesicles promote gastric cancer metastasis via VEGF/AKT/eNOS and AKT/mTOR pathways by Chen-li Zhang, Chan-yuan Zhao, Jia-ming Dong, Cun-pu Du, Bin-sheng Wang, Chen-yu Wang, Wei Liu, Yu-ping Wang, Xiao-yu Zhang, Quan Zhou, Wei Cai, Yun Dang, Li-na Shang, Ai-jun Yang, Min Wang, Min Li

“…However, it remains unclear which effector molecule in the EV structure is the key factor of EV-mediated tumor metastasis and the underlying molecular mechanism. …”
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Experimental Study on Peak Shaving with Self-Preheating Combustion Equipped with a Novel Compact Fluidized Modification Device by Hongliang Ding, Shuyun Li, Ziqu Ouyang, Shujun Zhu, Xiongwei Zeng, Haoyang Zhou, Kun Su, Hongshuai Wang, Jicheng Hui

“…By optimizing burner structure and operational parameters, original NO<i>_x</i> emissions decreased to a minimum of 77.93 mg/m³ with high <i>η</i> of 98.59% at low load of 30%.…”
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CORRECTION OF HYPODINAMY AS A FACTOR OF THE RISK OF OBESITY DEVELOPMENT IN FIRE-RESCUERS by E. V. BURDYUKOVA, A. N. ARKHANGELSKAYA, S. N. ALEKSEENKO, I. A. YAKIREVICH, E. A. DMITRIEVA, O. P. KARAZHELYASKOV, M. V. IVKINA, K. G. GUREVICH

“…A questionnaire was conducted to identify hypodynamia (according to the IPAQ questionnaire) and the nutrition structure (according to the questionnaire on the food label literacy questionnaire, past). …”
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Expert review in diagnostic, therapeutic and follow-up of Fabry disease in Latin America based on patient care standards by Roberto Giugliani, Juan Politei, Ana Martins, Nelson Murillo, Paula Rozenfeld, Mauricio Lopera, Sergio Salgado, Gustavo Quirós, Charles Marques Lourenço, Osvaldo Vieira, Hernán Amartino, Fernando Perretta, Sandra Marques e Silva, Joseph Brooks, Laura Titievsky, Jacobo Villalobos, Cassiano Braga, Harris A. Peñaranda

“…In Latin-American countries, it is difficult to guarantee this comprehensive and coordinated management, due to limited public policies related to orphan diseases diagnosis, treatment and follow up.It is considered crucial to structure support networks specialized in Fabry disease and generate partnerships with health institutions and other health system stakeholders, that would articulate and coordinate patients and relatives counseling and management, establish the specific pharmacological treatment to reduce the progression of the disease and the systemic involvement, deciding between the administration of enzyme replacement therapy or the most recent option of oral management with pharmacological chaperone both with proven effectiveness. …”
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Ginsenoside Rb1 ameliorates post-doxorubicin treatment myocardial hypertrophy via CaN/NFATc4/GATA4 by Jin-Jin Chang, Li-Xia Xu, Wen-Jing Yi, Huan-Huan Zhang, Jun-Wei Zhang, Bin Zheng, Ping-Ying Fu, Rui-Lan He, Rui-Xing Wang, Jian-Feng Jiang, Long-Xin Gui, Min-Xia Wu, Jun-Jin Lin, Zhi-Hong Huang, Jia-Lin Song, Mo-Jun Lin, Hai-Xia Jiao, Zhi-Juan Wu

“…Rb1 also relieved myocardial fibrosis and subcellar structure changes and improved the cardiac hemodynamics of post-DOX treatment mice. …”
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High prevalence and pathogenicity of Cryptosporidium serpentis in snakes in southern China by Falei Li, Xinrui Wang, Lihua Xiao, Yaoyu Feng, Yaqiong Guo

“…In pet snakes infected with C. serpentis, the gastric mucosal epithelial cells were heavily colonised by the parasites, resulting in significant damage to the villus structure. The results of this study indicate that C. serpentis is prevalent in snakes in southern China and has significant pathogenicity to snakes.…”
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Bidirectional associations among positive affect, anhedonia and meaning in life during major depressive episode: ecological momentary assessment study in unipolar and bipolar indiv... by Heidi Ka Ying Lo, Roger S. McIntyre, Iris Wai Tung Tsui, Fiona Yan Yee Ho, Ting Kin Ng, Corine Sau Man Wong, Suet Ying Yuen, Chit Tat Lee, Chun Yin Poon, Inez Myin-Germeys, Ka Fai Chung

“…Multilevel modelling analysis was conducted, with estimation of first-order autoregressive model structure and time-lagged relationship between pleasure and positive affect. …”
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Calcaratarin D, a labdane diterpenoid, attenuates bleomycin-induced pulmonary fibrosis by blocking Wnt/β-catenin signaling pathway by Wupeng Liao, Yuet Ang, Adrian C.L. Kee, Valencia Lim, Albert Y.H. Lim, Christina L.L. Chai, W.S. Fred Wong

“…The antifibrotic action of CalD was shown to be dependent on its α,β-unsaturated γ-butyrolactone structure that is essential for CalD to form covalent interaction with cellular protein targets. …”
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Development and preliminary validation of a Chinese Physical Activity Parenting Practices Scale (3–6 years) by Ren Na, Ying Liang, Haiyue Zhang, Zhe Yang, Nan Li, Wei Zhang, Han Tang, Weiliang Ye, Linyuan Zhang, Xun Jiang, Lei Shang

“…We ultimately developed a formal version of the Chinese Physical Activity Parenting Practices Scale (CPAPPS) using the remaining 30 items. We examined the structure of the scale using factor analysis and evaluated its reliability, validity, and discriminant ability using data from 899 parents of children aged 3–6 years.ResultsThe CPAPPS includes 30 items in 6 dimensions scored on a 5-point Likert scale. …”
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Genome-Wide Identification of <i>G3BP</i> Family in U’s Triangle <i>Brassica</i> Species and Analysis of Its Expression in <i>B. napus</i> by Alain Tseke Inkabanga, Qiheng Zhang, Shanshan Wang, Yanni Li, Jingyi Chen, Li Huang, Xiang Li, Zihan Deng, Xiao Yang, Mengxin Luo, Lingxia Peng, Keran Ren, Yourong Chai, Yufei Xue

“…We then analyzed their gene structure, protein motifs, gene duplication type, phylogeny, subcellular localization, SSR loci, and upstream miRNAs. …”
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Genomic interrogation of invasive group A Streptococcus (iGAS) epidemiology and COVID-19 impacts in Victoria, Australia: a 6-year retrospective studyResearch in context by Jacqueline M. Morris, Jake A. Lacey, Kerrie Stevens, Lamali Sadeesh Kumar, Mathilda Wilmot, Janet Strachan, Marion Easton, Daneeta Hennessy, Tony M. Korman, Andrew J. Daley, Katherine B. Gibney, Adam W.J. Jenney, Steven Y.C. Tong, Benjamin P. Howden, Norelle L. Sherry

“…The identification of the M1Aus sub-lineage emphasises the need for continued genomic surveillance and monitoring of iGAS strains, particularly in the context of emerging global sub-lineages and shifts in population structure. Funding: MDU PHL—Department of Health, Victoria. …”
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Compact Ionized Gas Region Surrounded by Porous Neutral Gas in a Dusty Lyman Break Galaxy at Redshift z = 8.312 by Masato Hagimoto, Yoichi Tamura, Akio K. Inoue, Hideki Umehata, Tom J. L. C. Bakx, Takuya Hashimoto, Ken Mawatari, Yuma Sugahara, Yoshinobu Fudamoto, Yuichi Harikane, Hiroshi Matsuo, Akio Taniguchi

“…Porous interstellar medium (ISM) structure in galaxies at the epoch of reionization gives us a hint to understand what types of galaxies contribute to reionization. …”
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Optical and electrical properties of pristine and transition Metals-doped graphene quantum dots as gas sensors toward H2O and NO2: A first principles study by Hamideh Sharifpour, Naser Hakimi Raad, Ebrahim Nadimi, Negin Manavizadeh, Siavosh Samoodi

“…Our findings indicate that the most favorable doping site within the GQDs structure is the center of a carbon hexagon (hollow site, H). …”
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Tissue-engineered vascular patches: comparative characteristics and preclinical test results in a sheep model by L. V. Antonova, A. V. Mironov, A. R. Shabaev, V. N. Silnikov, E. O. Krivkina, V. G. Matveeva, E. A. Velikanova, E. A. Senokosova, M. Yu. Khanova, V. V. Sevostyanova, T. V. Glushkova, R. A. Mukhamadiyarov, L. S. Barbarash

“…In in vitro experiments, the surface structure, physicomechanical and hemocompatibility properties were evaluated. …”
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Three-dimensional cell sheet model improves in vitro prediction accuracy of osteogenic potential for biodegradable magnesium-based metals by Liangwei Chen, Guanxi Wu, Siyu Liu, Ziyu Yan, Honglei Yue, Jianhua Zhu, Na Ge, Yifei Wang, Qingxiang Li, Guanqi Liu, Tingting Zhang, Haowen Zheng, Shaozhe Xin, Guangyunhao Sun, Chuanbin Guo, Jianmin Han

“…Histological analyses revealed a stable three-dimensional structure with elevated cell-cell interaction proteins, including N-Cadherin, Fibronectin, and Vinculin, along with enhanced osteogenic potential. …”
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Anti-inflammatory effect of glucose—mannose binding lectins isolated from Brazilian beans by A. M. S. Assreuy, M. D. Shibuya, G. J. Martins, M. L. P. De Souza, B. S. Cavada, R. A. Moreira, J. T. A. Oliveira, R. A. Ribeiro, C. A. Flores

“…Because of a lectin domain present in the selectin structure, we investigated the anti-inflammtory activity of six mannose–glucose binding lectins from brazilian beans: Dioclea guianensis-DguiL; D. grandiflora-DgL; Cratylia floribunda-CfL; D. violacea-D.vL; D. virgata-DvirL and Canavalia brasiliensis-ConBr. …”
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