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105941
Molecular epidemiology of Neisseria gonorrhoeae isolates in Russia, 2015–2023: current trends and forecasting
Published 2025-02-01“…Two clusters of isolates pose a particular threat to Russia: NG-MAST G2212, linked to MLST 1901/1902, carries a mosaic structure in the penA gene; G12302, linked to MLST 9363, contains mosaic alleles in the mtrR and mtrD genes. …”
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105942
Historic and contemporary selection define conservation units for a short-range endemic within an anthropogenically-altered riverscape
Published 2025-10-01“…Yet these are much less apparent in range-restricted forms where anthropogenic impacts, topography, and population structure are minimized. Here, short-range-endemics (SREs) are noteworthy for having historic habitats abridged, temporal recolonizations curtailed, and anthropogenic extinctions accelerated. …”
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105943
DIAGNOSTICS, TREATMENT, ASSOCIATED CARDIOVASCULAR AND CONCOMITANT NON-CARDIAC DISEASES IN PATIENTS WITH DIAGNOSIS OF “ATRIAL FIBRILLATION” IN REAL OUTPATIENT PRACTICE (ACCORDING TO...
Published 2015-09-01“…Aim. To study the structure of risk factors and associated cardiovascular and concomitant non-cardiac diseases in patients with atrial fibrillation (AF) on the base of the data of registry, and to estimate diagnostics and treatment quality in real outpatient practice in the Ryazan region with high cardiovascular mortality rate.Material and methods. …”
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105944
Genome-wide analysis of RAD23 gene family and a functional characterization of AcRAD23D1 in drought resistance in Actinidia
Published 2025-05-01“…In this study, we identified six AcRAD23 genes in kiwifruit and further analyzed their phylogenetic relationships, gene structure, conserved motif composition and cis-acting element in the promoter. …”
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105945
Chromatin-associated cullin-RING E3 ubiquitin ligases: keeping transcriptionally active NF-κB in check
Published 2025-04-01“…Our recent work demonstrates that WSB1 and WSB2 (WSB1/2), two additional SOCS-box proteins with structurally similar WD40 repeat domains, function as substrate-recognizing subunits of ECSWSB1/2 to specifically mediate the ubiquitination and degradation of chromatin-associated RelA methylated at Lys314/315. …”
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105946
Fruit-derived bioactive compounds of Malus domestica as novel therapeutic inhibitors against Monkeypox and Marburg virus: A computational based drug discovery study
Published 2025-06-01“…Molecular docking studies confirmed stable interactions between the selected compounds and viral target proteins, 4QWO, a protein structure associated with monkeypox virus, and 4OR8, related to the Marburg virus. …”
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105947
The Oxidation–Deuteration Processes of Large, Astronomically Relevant Cationic Polycyclic Aromatic Hydrocarbons
Published 2025-01-01“…Furthermore, the oxidized–deuterated TNPP cations ([C _40 H _m D _n O _x ] ^+ ) are well formed upon simultaneous reaction with O and D atoms. The structure of the oxidized–deuterated TNPP cations and the bonding energy for these reaction pathways were investigated with theoretical calculations. …”
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105948
Results of preclinical trials in a sheep model of biodegradable small-diameter vascular grafts
Published 2022-09-01“…The physical and mechanical properties of the studied matrix groups were evaluated, the surface structure of vascular grafts before and after implantation was assessed. …”
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105949
Clostridium butyricum enhances cognitive function in APP/PS1 mice by modulating neuropathology and regulating acetic acid levels in the gut microbiota
Published 2025-08-01“…While not altering the overall gut flora structure, CBM588 increased acetate-producing bacteria and decreased pro-inflammatory genera, reducing lipopolysaccharide levels. …”
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105950
dyphAI dynamic pharmacophore modeling with AI: a tool for efficient screening of new acetylcholinesterase inhibitors
Published 2025-02-01“…Experimental results revealed that molecules, 4 (P-1894047), with its complex multi-ring structure and numerous hydrogen bond acceptors, and 7 (P-2652815), characterized by a flexible, polar framework with ten hydrogen bond donors and acceptors, exhibited IC₅₀ values lower than or equal to that of the control (galantamine), indicating potent inhibitory activity. …”
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105951
Association between mitophagy and NLRP3 inflammasome in uric acid nephropathy
Published 2024-12-01“…H&E staining assessed renal structure, ROS levels were measured with 2, 7-dichlorofluorescin diacetate, and ELISA measured serum markers (creatinine, UA, cystatin C, NGAL, IL-1β, IL-18). …”
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105952
The professional careers of former Portuguese football players: a sociodemographic and professional approach
Published 2025-07-01“…Quantitative data was collected from a validated semi-structure interview guide. Results and Discussion: Former Portuguese players had a career of 15.2 ± 3.1 years with more 6.4 ± 2.2 years of youth federated formation. …”
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105953
Discovery of populations of the critically endangered coral Rhizopsammia wellingtoni in the Galápagos mesophotic zone
Published 2025-08-01“…Video transects conducted at 10 m depth intervals above 50 m failed to encounter any corals. Size structure varied considerably: 74% of the corals found at the southernmost site of Cuatro Hermanos were large colonies composed of multiple polyps, while 26% were solitary individuals. …”
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105954
H2MV (v1.0): global physically constrained deep learning water cycle model with vegetation
Published 2025-05-01“…The proposed model is open-source and has a highly flexible and modular structure to facilitate future integration of carbon and energy cycles, advancing toward a hybrid land surface model.…”
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105955
The Association of Lipoprotein(a) and Stroke Recurrence: A Systematic Review and Meta-Analysis
Published 2025-05-01“…Background and Purpose Lipoprotein(a) [Lp(a)] is a lipoprotein structurally similar to low-density lipoprotein and is considered a genetically determined risk factor for cardiovascular disease. …”
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105956
Whole exon screening of SLC2A4 gene and the association of rs5435 with type 2 diabetes in a Bangladeshi case-control study
Published 2025-09-01“…Additionally, in silico analysis revealed that the rs5435 variant introduces an additional loop in the mRNA secondary structure, which is energetically less stable and therefore may interfere with the protein’s biological function and play a role in the pathogenesis of T2D. …”
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105957
Parameterised analysis of blade profiles within electric submersible pump for enhancing energy conversion efficiency
Published 2025-12-01“…A major challenge in ESP design is that the multi-stage series structure promotes the propagation and interaction of unsteady flow between stages, which can significantly reduce efficiency and operational reliability and presents substantial difficulties for effective optimisation. …”
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105958
An overall study on efficient Cr (VI) adsorbents for improving of the application value of Chlorella pyrenoidosa
Published 2025-09-01“…The results show that a porous structure with sufficient active functional groups (O-H, pyrrole N, CO, C-O-C, C-O and pyridine N) and remarkable surface area can be well realized. …”
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105959
Crucial areas of the economic analysis of public cancer care
Published 2020-02-01“…In addition, we focused on significant studies conducted either on the national or international level.Results and discussion. In principle, the structure of total costs is determined by the health policy regarding the cancer care system. …”
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105960
Green synthesis and characterization of silver-doped ZnO nanoparticles using tobacco leaf extract: A novel hydrothermal approach for antibacterial and antifungal applications
Published 2025-04-01“…FTIR confirmed functional groups, while x-ray diffraction (XRD) validated the hexagonal wurtzite ZnO structure. SEM imaging revealed a nanosheet morphology. …”
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