Motor and Nonmotor Symptoms of Parkinson’s Disease: Antagonistic Pleiotropy Phenomena Derived from α-Synuclein Evolvability? by Yoshiki Takamatsu, Masayo Fujita, Gilbert J. Ho, Ryoko Wada, Shuei Sugama, Takato Takenouchi, Masaaki Waragai, Eliezer Masliah, Makoto Hashimoto

“…Based on the heterogeneity of protofibrillar AP forms in terms of structure and cytotoxicity, we recently proposed that APs might act as vehicles to deliver information regarding diverse internal and environmental stressors. …”
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Review of the Epidemiological Situation on Ixodidae Tick-Borne Borrelioses in the Russian Federation in 2010–2024 and Forecast for 2025 by S. A. Rudakova, O. E. Teslova, N. E. Mutalinova, N. V. Rudakov, N. A. Pen’evskaya, Yu. F. Kuz’menko, D. V. Trankvilevsky

“…Effective control of the ITBB epidemic situation is possible provided that the volume of preventive measures is maintained, and zoological-entomological monitoring of the activity and structure of natural foci is strengthened.…”
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Numerical Investigation of Factors Influencing Multiple Hydraulic Fracture Propagation from Directional Long Boreholes in Coal Seam Roofs by Maolin Yang, Shuai Lv, Yu Meng, Xing Wang, Sicheng Wang, Jiangfu He

“…In this paper, we developed a fluid–structure coupling numerical simulation model for hydraulic fracturing based on the element damage theory, and have systematically examined the effects of both engineering parameters and geological factors on the hydraulic fracture propagation behavior of the segmented fracturing of coal seam roofs. …”
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An Anodic Target Strategy for Microfocused X-Ray Device: Enhancing and Tuning Effects of Molybdenum Nanostructures on Radiation Properties by Fengyuan Liu, Shaozhi Deng, Jia Shi, Yanlin Ke, Fangfei Ming, Shuai Tang, Huanjun Chen, Yan Shen

“…The effective focal spot size decreases when transforming the cylinder structure into a cone, achieving better balance between focal spot and radiation flux at conification degrees <inline-formula> <tex-math notation="LaTeX">$\alpha _{\mathrm {c}} \lt 0.6$ </tex-math></inline-formula>. …”
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Epidemiology, Transmission, and Evolution of Japanese Encephalitis Virus by Chengcheng Peng, Huiling Qin, Fan Yu, Yujia Hao, Yuge Yuan, Wenzhou Ma, Duo Zhang, Pengpeng Xiao, Nan Li

“…E and NS1 were emphatically analyzed for amino acid variation and predicted protein structure. Gene recombination and the evolutionary rate of JEV were analyzed using RDP 4 and BEAST. …”
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Effects of different protein and lipid levels on the growth performance, intestinal health and intestinal microflora of pikeperch (Sander lucioperca) juvenile by Jie Zhao, Yang Liu, Zhipeng Sun, Liansheng Wang, Ze Fan, Tianqi Liu, Kexin Zhang, Yihua Xu, Xianhu Zheng, Cuiyun Lu

“…When the protein level of the feed was 51 % and the lipid level was 18 %, the growth performance of juvenile pikeperch was the best, and there was no obvious tissue damage or inflammatory response. The structure of the intestinal microflora was also relatively stable, indicating that the optimal protein and lipid levels for juvenile pikeperch were 51 % and 18 %, respectively.…”
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Large Language Model–Assisted Surgical Consent Forms in Non-English Language: Content Analysis and Readability Evaluation by Namkee Oh, Jongman Kim, Sunghae Park, Sunghyo An, Eunjin Lee, Hayeon Do, Jiyoung Baik, Suk Min Gwon, Jinsoo Rhu, Gyu-Seong Choi, Seonmin Park, Jai Young Cho, Hae Won Lee, Boram Lee, Eun Sung Jeong, Jeong-Moo Lee, YoungRok Choi, Jieun Kwon, Kyeong Deok Kim, Seok-Hwan Kim, Gwang-Sik Chun

“…Thereafter, readability was assessed using KReaD and Natmal indices, while text structure was evaluated based on character count, word count, sentence count, words per sentence, and difficult word ratio. …”
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Prospective evaluation of CYP19A1-mediated aromatase inhibitors for ER+ breast cancers by ultra-high performance liquid chromatography tandem mass spectrometry supported by in sili... by N.J. Gumede, K. Bisetty, L. Escuder-Gilabert, M.J. Medina-Hernandez, S. Sagrado

“…Docking with metal constraints validated the binding network, revealing strong hydrogen bonds with ASP309, MET374, and a metal ligand coordination between the heme iron atom of CYP19A1 and compound 12. We have performed Structure Activity Relationship (SAR) studies on compound 12, however the results cannot be disclosed for now since they are patent pending. …”
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Separating Subjective from Objective Food Value in the Human Insula: An Exploratory Study Using Intracranial EEG by Benjamin Hébert-Seropian, Olivier Boucher, Daphné Citherlet, Manon Robert, François Richer, Dang Khoa Nguyen

“…<b>Background/Objectives</b>: The human insula is a key structure implicated in integrating internal states and external food cues, yet its precise role remains unclear, in part due to the temporal limitations of neuroimaging techniques like fMRI. …”
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Extended Emission-line Region in a Poststarburst Galaxy Hosting Tidal Disruption Event AT2019qiz and Quasiperiodic Eruptions by Yifei Xiong, Ning Jiang, Zhen Pan, Lei Hao, Zhenzhen Li

“…The high spatial-resolution data reveal a biconical emission structure approximately 3.7 kpc in scale within the galactic center, characterized by a prominent [O iii ] line in the nucleus and significant [N ii ] line emission extending into the EELR. …”
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Melatonin regulated through GhTDC5 enhances tryptophan decarboxylase against drought stress in cotton by Xin Yu, Xiugui Chen, Ning Wang, Maohua Dai, Zhining Yang, Yapeng Fan, Yuping Sun, Xinrui Zhang, Ruize Song, Menghao Zhang, Hao Lan, Fange Wu, Hui Huang, Xiao Chen, Lidong Wang, Xuke Lu, Shuai Wang, Lixue Guo, Junjuan Wang, Lanjie Zhao, Keyun Feng, Jing Jiang, Wuwei Ye

“…This study systematically analyzed the evolutionary relationships of the TDC gene family in four cotton species using bioinformatics approaches, including phylogenetic analysis, chromosomal localization, gene structure, conserved motifs, cis-acting elements, synteny, and expression patterns. …”
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Modeling of Multi-Frequency Microwave Backscatter and Emission of Land Surface by a Community Land Active Passive Microwave Radiative Transfer Modeling Platform by Hong Zhao, Yijian Zeng, Jan G. Hofste, Ting Duan, Jun Wen, Zhongbo Su

“…By assessing CLAP’s performance using in situ and satellite multi-frequency measurements of grassland backscatter and emission at the Maqu site, the impacts of different grass properties (i.e., structure, water, and temperature dynamics) and soil conditions (i.e., varied moisture and temperature profiles) are investigated. …”
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RGB and RGNIR image dataset for machine learning in plastic waste detectionZENODO by Owen Tamin, Ervin Gubin Moung, Jamal Ahmad Dargham, Samsul Ariffin Abdul Karim, Ashraf Osman Ibrahim, Nada Adam, Hadia Abdelgader Osman

“…Moreover, incorporating near-infrared (NIR) spectral data into machine learning models can reveal crucial information about plastic waste composition and structure that remains invisible in standard RGB images. …”
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Microscopic pore-fracture combination types and their impact on exploration and development: in case of deep shale gas reservoirs in the Luzhou area of the Sichuan Basin by Zhiming Hu, Zhiming Hu, Xianggang Duan, Xianggang Duan, Yonghong Fu, Yan Chang, Yan Chang, Jin Chang, Jin Chang, Yuqiang Jiang, Linyao Yu

“…Therefore, during the development of these two types of shale gas reservoirs, it is imperative to enhance and optimize fracturing techniques to create a more intricate fracture network structure, thereby enabling the release of shale gas trapped in poorly connected pores. …”
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Functional transformation of settlements in coal exploitation zones: A case study of the municipality of Stanari in Republic of Srpska (Bosnia and Herzegovina) by Delić Dragica, Gatarić Dragica, Ratkaj Ivan, Mandić Mira, Poljašević Branka Zolak, Sabljić Luka, Lukić Tin

“…The results show a statistically significant association between these decisions and respondents’ spatial affiliation, suggesting possible future changes in the functional structure and hierarchy of the settlement network. …”
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Psychometric Evaluation of the Malay Version of Weight Stigma Exposure Inventory (WeSEI) Among Malaysian Young Adults by Wan Ying Gan PhD, I-Hua Chen PhD, Serene En Hui Tung PhD, Ru-Yi Huang MD, Wai Chuen Poon PhD, Yan-Li Siaw PhD, Wenjia Li PhD, Jung-Sheng Chen PhD, Kerry M. O’Brien PhD, Mark D. Griffiths PhD, Chung-Ying Lin PhD

“…The CFA results supported the 7-factor structure for the WeSEI. All subscales of the WeSEI and the entire WeSEI had good internal consistency (ω > 0.85). …”
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Two Nonsense GLI3 Variants Are Identified in Two Chinese Families With Polydactyly by Yongzhen Qi, Kai Liu, Yuda Wei, Xiaxia Liu, Liangqian Jiang, Juan Teng, Baoqiang Chong, Shuqi Zheng, Xiangyu Zhao, Lin Li

“…Additionally, Swiss Model was utilized to predict the effects of mutations on protein tertiary structure. Results The mutations of GLI3 (NM_000168.6: c.3342dupC; p. …”
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Elongation of Long‐Chain Fatty Acid Family Member 6 (Elovl6)‐Driven Fatty Acid Metabolism Regulates Vascular Smooth Muscle Cell Phenotype Through AMP‐Activated Protein Kinase/Krüpp... by Hiroaki Sunaga, Hiroki Matsui, Saki Anjo, Mas Risky A. A. Syamsunarno, Norimichi Koitabashi, Tatsuya Iso, Takashi Matsuzaka, Hitoshi Shimano, Tomoyuki Yokoyama, Masahiko Kurabayashi

“…Background Fatty acids constitute the critical components of cell structure and function, and dysregulation of fatty acid composition may exert diverging vascular effects including proliferation, migration, and differentiation of vascular smooth muscle cells (VSMCs). …”
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Cleft lip and palate as predictors of EEC syndrome: a clinical case by A. A. Mamedov, S. A. Parshikova, Yu. O. Volkov, L. A. Mazurina, G. Ma, H. Guo, N. V. Gorlova

“…Cleft lip and palate is one of the most common congenital pathologies of the face and ranks 3rd in the structure of all congenital malformations. An isolated form of this pathology occurs in 7,6-41,4% of cases; as part of symptomatic complexes of a cleft lip and palate, 21,1-61,2% are described. …”
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PCM enhanced concrete panels allow to reduce overheating in lightweight buildings by Tomasz Kisilewicz, Anna Zastawna-Rumin, Katarzyna Nowak, Andal Lakshumiah, Annie Sweetlin Jebarani

“…In a very simple modeled object with a light wooden structure, intensively cooled during the night, the influence of the type of internal cladding on the internal thermal comfort in the summer was analyzed. …”
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