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104621
Insights into Natural Products from Marine-Derived Fungi with Antimycobacterial Properties: Opportunities and Challenges
Published 2025-07-01“…Several compounds exhibit potent activity through uncommon mechanisms, including the inhibition of mycobacterial protein tyrosine phosphatases (MptpB/MptpA), protein kinase PknG, ATP synthase and the disruption of mycobacterial DNA via G-quadruplex stabilization. Structure–activity relationship (SAR) trends are highlighted for the most potent agents, illuminating how specific functional groups underpin target engagement and potency. …”
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104622
Repeated evolution on oceanic islands: comparative genomics reveals species-specific processes in birds
Published 2024-11-01“…Our results suggest that the genomic mechanisms involved in the divergence upon island colonization—such as chromosomal inversions, and historical factors like recurrent selection—differ in each species, despite the highly conserved structure of avian genomes and the similar selective factors involved. …”
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104623
Incidence rate and related factors of depression in older adult patients with somatization symptoms
Published 2025-07-01“…Predictors of incident depressive symptoms were identified using purposeful multivariable logistic regression, with Firth correction applied for small-cell bias. Confounding structure was guided by a directed acyclic graph (DAG), and internal consistency was assessed (SSS: Cronbach’s α = 0.89; PHQ-2: α = 0.78).ResultsDuring the 12-month follow-up, 20.37% of participants (n = 33) developed clinically significant depressive symptoms. …”
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104624
The medical student stressor questionnaire (MSSQ): validation and reliability in Turkish students
Published 2025-08-01“…Conclusion In conclusion, this study has provided preliminary evidence for the validity and reliability of a Turkish version of the MSSQ. The six-factor structure was confirmed by CFA. We propose using the Turkish version of MSSQ to evaluate the stress level of medical students. …”
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104625
Intensive Care Outcomes and Differences Between Survivors and Deceased Patients in a Terminal Coma: A Retrospective Observational Study
Published 2022-12-01“…Statistical processing of the obtained study results was carried out via nonparametric techniques using Microsoft Excel 10 (Microsoft, USA) and Statistica 6.0 (StatSoft, USA).Results. The mortality structure against the background of a terminal coma in the following diagnosis: polytrauma — 54%, hemorrhagic stroke — 56%, isolated traumatic brain injury — 37%, acute cerebrovascular accidents (ischemic type) — 33% and acute posthypoxic dyscirculatory encephalopathy — 11%. …”
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104626
Comparative analysis of protocols for decellularization of corneal lenticular tissue
Published 2021-07-01“…However, the Trypsin-EDTA protocol led to significant damage to the extracellular matrix structure, which negatively affected the transparency of corneal tissue-engineered constructs. …”
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104627
Transcriptome analysis of aerotolerant and aerosensitive Campylobacter jejuni strains in aerobic conditions
Published 2025-07-01“…When category S was excluded, COG category J (translation, ribosomal structure, and biogenesis) had the highest number of DEGs between aerobic vs. microaerobic conditions with downregulated genes occurring at most timepoints in the two strains. …”
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104628
The Impact of Health Consciousness and Environmental Awareness on Sports Enthusiasts’ Purchase Intentions for Sustainable Sports Products
Published 2025-02-01“…The collected data were analyzed using SPSS and AMOS software to systematically evaluate the research hypotheses and the model’s applicability. (3) Results: The model exhibited excellent fit indices, with a χ<sup>2</sup>/df value of 2.129, an RMSEA value of 0.053, an RMR value of 0.029, and GFI, CFI, NFI, and NNFI values all exceeding 0.90, indicating that the model structure adequately explained the relationships among latent variables. …”
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104629
Epidemiological characteristics of papillomavirus infection of anogenital localization in Tatarstan republic
Published 2022-10-01“…The analysis of long-term dynamics of incidence of the population as a whole and in age and sex groups is carried out. The structure of the incidence of anogenital warts was assessed. …”
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104630
Importance of abiotic factors and hydroperiod for the zooplankton community from ponds with different hydrological dynamics
Published 2025-06-01“…Hydroperiod can influence the structure of aquatic ecosystems and the factors determining species occurrence in these water bodies. …”
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104631
Novel candidate genes may be possible predisposing factors revealed by whole exome sequencing in familial esophageal squamous cell carcinoma
Published 2017-04-01“…Bioinformatics software applications were utilized to exploit statistical algorithms to demonstrate protein structure and variants conservation. Polymorphic regions were excluded by false-positive investigations. …”
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104632
ASSESSMENT OF ENTRY LEVEL OF MARKETOLOGIST LEADERSHIP COMPETENCE FORMATION
Published 2021-06-01“…Criteria (motivational, cognitive, activity and personality) and indicators for the assessment of leadership competence level of future marketologists according to its structure were developed and described, diagnostic methods revealed, identified and the levels of competence formation (high, sufficient, low) described. …”
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104633
Synthesis, physical-chemical and biological properties of 7-benzyl-3-methyl-8-thioxanthine derivatives
Published 2017-12-01“…Under short-time heating up of the initial 7-benzyl-3-methyl-8-thioxanthine with alkyl, alkenyl, benzyl halides or heteroalkylchlorides in a water-propanol-2 mixture in the presence of an equimolar amount of sodium hydroxide leads to the formation of 8-S-substituted of 7-benzyl-3-methylxanthines. Structure of synthesized compounds was definitely proved by NMR-spectroscopy. …”
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104634
International and Russian Legal Regulation of the Turnover of Crypto-assets: Conceptual-Terminological Correlation
Published 2023-08-01“…Objective: to assess the Russian legislation for its compliance with the international-legal approaches to shaping symmetrical regulation of crypto-assets and possibility to complement it with new internationallegal categories reflecting the in-depth changes in the global economy and structure of international finance, determined by the broad introduction of new financial technologies based on distributed ledger technologies.Methods: the methodological basis of the research is a set of general scientific methods of scientific cognition, among which of utmost importance are special-legal (formal-legal and comparative-legal) methods, complemented with risk-oriented approach, legal modeling and juridical forecasting. …”
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104635
YOLO-DAFS: A Composite-Enhanced Underwater Object Detection Algorithm
Published 2025-05-01“…The backbone incorporates a DualBottleneck module to enhance feature extraction, replacing the standard bottleneck structure in C3k, thus enhancing the feature extraction and the channel aggregation. …”
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104636
Quality Evaluation of Whole Wheat Sourdough Fermented at Different Temperatures and Diversity Analysis and Breeding Selection of Lactic Acid Bacteria
Published 2025-04-01“…To investigate the impact of fermentation temperature on the quality and biodiversity of lactic acid bacteria (LAB) in whole wheat sourdough, full-length high-throughput sequencing technology was applied to systematically analyze the community structure and succession patterns of bacterial communities in sourdough samples fermented at different temperatures during the maturation process. …”
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104637
Exploring the effect on marine fish of electric fields of a fish‐protection
Published 2022-12-01“…Some differences on the reproductive system of the fish species studied in the structure of gonads and reactivity of cells were noted under the influence of the electric barrier. …”
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104638
Preparation of Double-Layered Nanofiber Film Loaded with Bayberry Pomace Anthocyanin Extract and Its Application in Shrimp Freshness Monitoring
Published 2025-05-01“…In this study, a double-layered nanofiber film (ZG/PUL-PVA-BAE) was prepared by incorporating a hydrophobic layer consisting of zein and gelatin (ZG) onto PUL-PVA-BAE, and its physical properties, structure, color response, stability, and application were studied. …”
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104639
Effect of Grain Sizes on Temperature Hysteresis of Ceramic Barium Titanate
Published 2025-05-01“…The influence of synthesis processes on the structure and grain size of ceramic barium titanate, as well as its dielectric properties, were studied. …”
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104640
Electrochemical diffusion signatures of solid-solution and phase-separating active materials in Li-ion batteries
Published 2025-01-01“…This study presents a comparative analysis of the electrochemical responses of these two classes of active materials using a multi-particle phase-field model, the structure and description of which are designed to promote easy interpretation by non-modelling experts. …”
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