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90661
A Peptide Antagonist of the ErbB1 Receptor Inhibits Receptor Activation, Tumor Cell Growth and Migration In Vitro and Xenograft Tumor Growth In Vivo
Published 2010-01-01“…The epidermal growth factor family of receptor tyrosine kinases (ErbBs) plays essential roles in tumorigenesis and cancer disease progression, and therefore has become an attractive target for structure-based drug design. ErbB receptors are activated by ligand-induced homo- and heterodimerization. …”
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90662
Effects of swimming training on cecum microorganisms and metabolites in rats with high fat diet
Published 2025-08-01“…The results show that feeding high-fat diet can cause tissue and organ lesions, cecal microbe and metabolite structure changes in rats. However, swimming training increased the content of beneficial microorganisms and metabolites in rats’ cecum. …”
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90663
Network analysis of headache diagnoses using international classification of headache disorders, 3rd edition
Published 2025-01-01“…In this study, we aim to elucidate how the hierarchical structure of ICHD-3 shapes the understanding of interconnectivity among headache disorders.MethodsA network comprises elements known as “nodes,” with the connections between them referred to as “edges.” …”
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90664
Characterization of porous cellulose triacetate derived from kapok fibres (Ceiba pentandra) as a tool to enhance crude oil absorption
Published 2025-02-01“…Polyvinylidene fluoride (PVDF) membranes are known for their hydrophobicity, chemical resistance, and thermal stability, but they are hindered by naturally low porosity due to the high-density polymer structure. To address this limitation, a porous polymer with synergistic properties was required. …”
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90665
DEVELOPMENT OF COMPLEX EQUIPMENT FOR PLASMA SPRAY CERAMIC COATINGS
Published 2017-01-01“…Methods of research is based on studies of structural elements composite plasma coatings system ZrO2 – Y2O3 obtained using developed complex equipment. …”
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90666
Effect of consuming blood-substitute feed on the transcriptome of the medicinal leech, Hirudo orientalis Utevsky and Trontelj, 2005 (Clitellata: Hirudinida)
Published 2024-12-01“…While leeches in the genus Hirudo have long been models for neurobiology, the molecular underpinnings of nervous system structure and function in this group remain largely unknown. …”
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90667
Application of the Christiansen Dividing-wall Column Configuration for Multicomponent System Separation
Published 2024-12-01“…While this simplified structure offers advantages in terms of implementation, its structural limitations lead to a reduced degrees of freedom for process control. …”
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90668
Virtual simulation analysis and verification on working stability of sugarcane tail-breaking mechanism
Published 2015-07-01“…According to the optimal structural parameters, the physical prototype verification test was operated with the whole stalk sugarcane harvester with anti-movement tail-breaking mechanism. …”
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90669
Sterol Biosynthesis Pathway as Target for Anti-trypanosomatid Drugs
Published 2009-01-01“…Sterols are constituents of the cellular membranes that are essential for their normal structure and function. In mammalian cells, cholesterol is the main sterol found in the various membranes. …”
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90670
Examining the genetic links between clusters of immune-mediated diseases and psychiatric disorders
Published 2025-07-01“…We utilized Genomic Structural Equation Modeling (Genomic SEM) to establish a factor structure across 11 immune-mediated diseases. …”
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90671
Slow Relaxation of the Magnetisation in a Two-Dimensional Metal–Organic Framework with a Layered Square Lattice
Published 2024-12-01“…Herein, we present the synthesis and structural characterisation of two layered MOFs with the asymmetric ligand 3-chloro,6-cyano-2,5-dihydroxy-1,4-benzoquinone dianion (C<sub>6</sub>O<sub>4</sub>(CN)Cl<sup>2−</sup> = chlorocyananilato). …”
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90672
Matrix Stiffness Affects Spheroid Invasion, Collagen Remodeling, and Effective Reach of Stress into ECM
Published 2025-06-01“…The extracellular matrix (ECM) provides structural support to cells, thereby forming a functional tissue. …”
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90673
Deep Learning-Based Denoising for Optical Coherence Tomography: Evaluating Self-Supervised and Generative Models Across Retinal Datasets
Published 2025-05-01“…The DnCNN and U-Net Autoencoder exhibited moderate performance, with slightly higher loss values, likely due to their sensitivity to fine structural variations. SwinIR Transformer performs comparably to convolutional-based models but slightly underperforms on structurally complex conditions such as macular holes and central serous retinopathy. …”
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90674
Research Progress on the Potential Pathogenesis of Persistent Postural–Perceptual Dizziness
Published 2025-01-01“…Recent studies have shown that the brain structure, activity, structural connectivity, and even cerebral perfusion of patients with PPPD differ from those of healthy individuals. …”
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90675
Automation of aeronautical information processing based on multi-agent technologies
Published 2022-02-01“…To achieve this goal, the problem-structural methodology of hybrid systems synthesis, which allows us to create self-organizing models, was selected. …”
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90676
Supporting Cardiovascular Risk Factor Management in Primary Care Clinics: The Relationship Between External Linkages and Organizational Change Preparedness
Published 2025-07-01“…However, primary care clinics that were linked structurally were associated with lower levels of change preparedness. …”
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90677
Blood atherogenic potential as a predictor of arterial hypertension among children living in ecologically unsafe territories of the Moldova Republic
Published 2013-06-01“…According to WHO, arterial hypertension (AH) determines the structure of morbidity, mortality, and disability of adult populations. …”
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90678
Cloning and expression analysis of maize fucosyltransferase gene SPINDLY
Published 2024-12-01“…Its secondary and tertiary structure is largely composed of alpha helix and random coil.(4)The subcellular localization of ZmSPY is predominantly observed in the nucleus.(5)The expression of ZmSPY is induced by phytohormones including GA, IAA, 6BA and ABA, and exhibits various expression patterns. …”
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90679
Evaluation of safflower varieties for productivity and quality in the arid conditions of the Northern Caspian region
Published 2023-11-01“…In a dry continental climate, safflower has an undeniable advantage over grains and oilseeds due to its morphological structure. The main advantage of this crop is that it is capable of extracting water from deep layers of soil with its developed root system, and due to the structural features of the vegetative mass, it can use it economically, while forming stable yields. …”
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90680
Research and application of bolter miner airborne drilling rig
Published 2025-03-01“…Based on the analysis of the excavation face’s working conditions and functional requirements, the overall structure design and operation process design of the new DR were completed. …”
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