Effect of a single-dose denosumab on mineral homeostasis in infertile men: insights from a pilot intervention study and a randomized controlled trial by Sam Kafai Yahyavi, Rune Holt, Li Juel Mortensen, Ida Marie Boisen, Lív Bech Árting, Anne Jørgensen, Anders Juul, Martin Blomberg Jensen

“…Methods Secondary data from two clinical trials designed to test the effect on semen quality were used: (1) a pilot intervention study with 12 men receiving a single-dose of 60 mg denosumab and (2) a single-center, double-blinded, randomized clinical trial, where 100 infertile men were randomized 1:1 to receive denosumab 60 mg once sc. or placebo. A linear mixed model for repeated measures was employed to analyze data from follow-up samples. …”
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Dynamic relationship between gut microbiota and post-necrotizing pancreatitis: insights from a multi-stage 16S rRNA sequencing study by Jiongdi Lu, Jiongdi Lu, Zhe Wang, Zhe Wang, Feng Cao, Feng Cao, Jia Li, Guofeng Ji, Guofeng Ji, Fei Li, Fei Li

“…Gut microbial diversity and composition were assessed using 16S rRNA sequencing, followed by bioinformatic analyses such as Alpha and Beta diversity metrics, linear discriminant analysis effect size (LEfSe), and functional pathway predictions. …”
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Association of Apgar score at 5 minutes with academic performance and intelligence in youth: A cohort study by Agnes Kielgast Ladelund, Frederik Jager Bruun, Julie Anna Slavensky, Steen Ladelund, Ulrik Schiøler Kesmodel

“…Associations between Apgar score at 5 minutes and school graduation, grades and attendance, and intelligence scores from conscription were analyzed using univariate and multivariate logistic and linear regressions. Results No association was found between Apgar score and graduating primary school. …”
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Judgment on the degree of fatty liver in different color livers for edible grass carp, Ctenopharyngodon idella by TIAN Juan, WEN Hua, ZENG Ling-bing, WU Fan, JIANG Ming, LIU Wei

“…The degree of hepatocyte fatty degeneration in normal liver, motley liver, blushing liver and yellowing liver was 1.10±0.30, 2.30±0.20, 3.40±0.50 and 4.00±0.20, respectively. After doing linear regression analysis, liver fat contents (Y) were negatively correlated with its moisture contents (X): Y = -1.089 9 X + 82.035 7, R² = 0.989 (P< 0.01); the positive area ratio (Y) were positively correlated with its crude fat content (X): Y = 0.970 2 X -0.209 0, R² = 0.973 (P<0.05); the crude fat content (Y) were positively correlated with the degree of hepatocyte fatty degeneration (X): Y = 3.662 4 X -1.788 6, R² = 0.985 (P< 0.01); the positive area ratios (Y) were also positively correlated with the degree of hepatocyte fatty degeneration (X): Y = 3.622 4 X -2.130 6, R² = 0.996 (P<0.01). …”
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County-level association between modifiable health behaviors and premature mortality in the United States by Abdul Mannan Khan Minhas, Kashvi Gupta, Erin D. Michos, Andrew J. Sauer, Laurence Sperling, Vijay Nambi, Layla Abushamat, Christie M. Ballantyne, Dmitry Abramov

“…Counties were divided into deciles based on the percentage of adults with physical inactivity, insufficient sleep, and current smoking (separate decile for each metric) from Behavioral Risk Factor Surveillance System in 2019. Multivariable linear regression were used to evaluate the association of premature AADR with physical inactivity, insufficient sleep, and current smoking (lowest deciles as reference), controlling for median county income as a social determinant of health.Results: A total of 3082 counties were included in the analysis. …”
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Joint Effect of Central Obesity and Family History on Hypertension in Type 2 Diabetes: A Cross-Sectional Study in China by Chen X, Chen L, Hu R, Yao W, Ma Z, Zhong J

“…WC was positively correlated with SBP (r = 0.25, P< 0.001) and DBP (r=0.27, P< 0.001), and showed a linear association with hypertension in both sexes (P for non-linearity> 0.05). …”
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Associations between within-day step accumulation pattern and clinical measures of physical function: a change-for-change analysis of longitudinal data in community-dwelling older... by Melvyn Hillsdon, Alexander Schoenfelder, Brad Metcalf, Afroditi Stathi, Max J. Western, Joss Langford

“…We used the frequency of stepping bouts, the time between them (mean and standard deviation) and their burstiness (short bursts of stepping bouts clustered together), to examine the daily patterns of step accumulation. Linear mixed-effects models were used to assess trends in stepping variables and their association with changes in objectively measured physical function (short physical performance battery: SPPB) over the two-year period. …”
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A Personalized, Texting-Based Conversational Agent to Address Sleep Disturbance in Individuals Who Have Survived Breast Cancer: Protocol for a Pilot Waitlist Randomized Controlled... by Chi-shan Tsai, Warren Szewczyk, Michelle Drerup, Jason Liao, Alexi Vasbinder, Heather Greenlee, Jaimee L Heffner, Rachel Yung, Kerryn W Reding

“…Quantitative analysis, such as t test, Fisher exact tests, and generalized linear models, will be used to assess feasibility, baseline group differences, and the outcomes of the intervention. …”
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Associations between trajectories of depressive symptoms and cognitive performance in Chinese adolescents by Zhen Xiang, Pei Xiao, Haoxue Wang, Kaiheng Zhu, Qi Jiang, Yanan Feng, Han Xiao, Ranran Song

“…The 6-year depressive symptom trajectories of adolescents were identified by the latent class mixed model. Linear regression models and Generalized Estimating Equation models were applied to test the associations between depressive symptom trajectories and cognitive performance. …”
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Exploring the Determinants of Physical and Mental Health among Patients with Non Specific Chronic Low Back Pain and Movement Control Impairment: A Cross-sectional Study by Manju Kaushik, Irshad Ahmad

“…The Pearson’s correlation test, univariate and multiple linear regression analysis were performed for the outcomes of physical and mental health domains at p-value of <0.05. …”
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Characterization of Stability Regions in the Discrete PID Gain Space via D-Partition Approach by Chun-Chong Fu, Chyi Hwang, Li-Shin Lu

“…In the study of linear control systems, D-partition theory provides a powerful technique for controller design by dividing the controller parameter space into stability regions, within which the number of unstable characteristic roots remains invariant. …”
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A rig for in vitro testing of the lumbar spine and pelvis simulating posterior, anterior and oblique trunk muscles by Georg Matziolis, Leah Bergner, Harun Hawi, Leandra Bauer, Matthias Woiczinski, Patrick Strube, Sophia Vogt

“…Three paired muscles were combined by individual linear actuators and simulated under force control (posterior, anterior and oblique trunk muscles). …”
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A New Method to Determine Central Wavelength and Optimal Bandwidth for Predicting Plant Nitrogen Uptake in Winter Wheat by Xin-feng YAO, Xia YAO, Yong-chao TIAN, Jun NI, Xiao-jun LIU, Wei-xing CAO, Yan ZHU

“…The plant N uptake index (PNUI) based on NDVI of 807 nm combined with 736 nm was selected as the optimal vegetation index, and a linear model was developed with R2 of 0.870 and RMSE of 1.546 g N m−2 for calibration, and R2 of 0.834, RMSE of 1.316 g N m−2, slope of 0.934, and intercept of 0.001 for validation. …”
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Adherence to the Mediterranean diet is associated with lower cancer-related fatigue: a cross-sectional analysis from NHANES 2017–2020 by Xueqin Xia, Xuehua Cao, Chen Gong, Yi Liu, Xiaoyuan Zhang, Limei Liao

“…AMED scores were calculated based on data from 24-h dietary recall interviews conducted on both day one and day two. Multiple linear regression modeling was used to explore the association between AMED scores and cancer-related fatigue, as well as the relationship between AMED scores and fatigue in the general population.ResultsA total of 6,413 adults aged 20 years and older were included in the study, with 707 identified as cancer patients. …”
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Public assistance program and food diversity among older people: a cross-sectional study using the Japan Gerontological Evaluation Study data by Kotone Tanaka, Daisuke Nishioka, Atsushi Nakagomi, Keiko Ueno, Kazushige Ide, Shiho Kino, Nobuko Murayama, Katsunori Kondo

“…To assess the relationship between receiving public assistance and the DVS, we calculated the unstandardized coefficient (β) and p values using a general linear model. Additionally, the interaction between public assistance and eating together was examined. …”
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Comparative analysis of four nutritional scores in predicting delirium in ICU patients by Chunchun Yu, Lefu Chen, Xiong Lei, Zhixiao Xu, Hongjun Zhao, Chengshui Chen, Chengshui Chen

“…Using area under the curve (AUC) evaluated the discriminatory ability of the adjusted models.ResultsThe RCS shows a strong linear connection between delirium and PNI (P for nonlinear = 0.66), as well as between delirium and CONUT score (P for nonlinear = 0.32). …”
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Assessing delays in accessing and completing radiotherapy for cervical cancer treatment: A multicenter survey of oncology providers in go further-funded countries in Sub-Saharan Af... by Caroline G. Kernell, Megan Kassick, Jessica M. George, Chidinma P. Anakwenze, Edward L. Trimble, Surbhi Grover

“…Nearly half (46.3 %) reported wait time of ≥two months for chemoradiotherapy consultation. 93.3 %, 71.4 %, 53.7 % and 73.3 % had access to at least one CT, linear accelerator, cobalt, and brachytherapy machine, respectively. …”
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Traffic injury as a medical and sanitary consequence of an emergency of man-made nature in Ukraine. Report four: analysis and characterization of the array of victims depending on... by S.O. Guryev, V.A. Kushnir, O.S. Soloviov, H.P. Kushnir

“…It was found that a large amount of damage in general causes a greater threat to the life of a victim of traffic accidents, but the trend is non-linear, that is, the survival is affected by other risk-creating factors. 2. …”
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Acupuncture versus cognitive behavioral therapy for anxiety among cancer survivors with insomnia: An exploratory analysis of a randomized clinical trial by Eunbin Kwag, Xiaotong Li, Sheila Garland, Karolina Bryl, Lauren Taylor, Qing S. Li, Lindsay Amann, Jun J. Mao, Kelly M. McConnell

“…Anxiety was assessed at baseline, week 8, and week 20 using HADS-A. A linear mixed-effects model was used to examine mean change in HADS-A scores. …”
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CD8-positive lymphocyte infiltration as a marker of anti-tumor immune response in rectal cancer: pre- and post-neoadjuvant radiotherapy comparison by Samaneh Salarvand, Romina Abyaneh, Abdorreza Raee, Mahdieh Yaghooti-Khorasani, Fariba Mohammadjani, Fatemeh Nili, Mahdi Aghili, Reza Ghalehtaki

“…An increase in CD8+ TILs was observed in both groups, with LCRT showing a median post-to-pre-treatment count ratio of 2.77 and SCRT showing 3.1 (P = 0.127). A generalized linear multivariate model adjusting for mucinous histology, surgical grade, and pathological stages revealed that SCRT was associated with a significantly higher post-to-pre-treatment CD8+ count ratio compared to LCRT (P = 0.03). …”
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