Equitable access to COVID-19 vaccines in Botswana: a scoping review by John T. Tlhakanelo, John T. Tlhakanelo, John Ele-Ojo Ataguba, John Ele-Ojo Ataguba, John Ele-Ojo Ataguba, John Ele-Ojo Ataguba, Vincent Pagiwa, Nankie Ramabu, Khutsafalo Kadimo, Dintle Molosiwa, Grace Njeri Muriithi, Daniel Malik Achala, Elizabeth Naa Adukwei Adote, Chinyere Ojiugo Mbachu, Senait Alemayehu Beshah, Senait Alemayehu Beshah, Nyasha Masuka, Chijioke Osinachi Nwosu, James Akazili, James Akazili, Chikezie Ifeanyi

“…COVID-19 vaccine delivery relied on existing Expanded Program on Immunization (EPI) structures and therefore experienced to existing EPI challenges including, lack of transport, shortage of human resources, and vaccine stock-outs.ConclusionsUnder-performance of immunization programs at the district level, characterized by declining immunization coverage and inadequate outreach services, exacerbates disparities in vaccine access. …”
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Premature ageing of lung alveoli and bone marrow cells from Terc deficient mice with different telomere lengths by Rosa Guerrero-López, Cristina Manguán-García, Carlos Carrascoso-Rubio, M. Luz Lozano, Marta Toldos-Torres, Laura García-Castro, Rebeca Sánchez-Dominguez, Omaira Alberquilla, Isabel Sánchez-Pérez, Maria Molina-Molina, Juan A. Bueren, Guillermo Guenechea, Rosario Perona, Leandro Sastre

“…Abstract Telomeres are terminal protective chromosome structures. Genetic variants in genes coding for proteins required for telomere maintenance cause rare, life-threatening Telomere Biology Disorders (TBDs) such as dyskeratosis congenita, aplastic anemia or pulmonary fibrosis. …”
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Therapeutic Effects of Cynodon dactylon (C. dactylon) against Polycystic Ovary Syndrome Induced by Letrozole in Adult Rats: Ovarian and Uterine Aspects by Masoumeh Ahmadi, Afshin Zare, Mohammad Reza Jafarzadeh Shirazi, Samaneh Askari, Arezoo Khoradmehr, Nadiar M Mussin, Asset A Kaliyev, Farzad Mohammad Rezazadeh, Saman Saedi, Mohammad Dadpasand Taromsari, Alidad Boostani, Nader Tanideh, Kulyash R. Zhilisbayeva, Ramazon Safarzoda Sharofiddin, Amin Tamadon

“…Ovarian and uterine structures were improved including reducing theca layer thickness, enhancing antral follicular areas, and a significant decrease in the luminal area of the perimetrial layer, endometrial glands, and the total uterine area when compared to the PCOS group. …”
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New Bioactive Polyketides from the Mangrove-Derived Fungus <i>Daldinia eschscholzii</i> HJX1P2 by Miao Yu, Yikang Qiu, Shiji Chen, Jueying Shi, Xiu Gong, Jiayi Feng, Fangru Lin, Weinv Zeng, Wenyuan Kang, Caijuan Zheng, Guolei Huang

“…Three new naphthalene–chroman dimer derivatives, daldinaphchromes A–C (<b>1</b>–<b>3</b>), two new chroman derivatives, daldichromes A (<b>5</b>) and B (<b>6</b>), along with five known compounds (<b>4</b>, <b>7</b>–<b>10</b>) were isolated from the mangrove-derived fungus <i>Daldinia eschscholzii</i> HJX1P2. Their structures and stereochemistries were elucidated through detailed NMR and MS analyses, calculated electronic circular dichroism, and comparison with previously reported data. …”
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Salivary attenuated total reflectance-fourier transform infrared spectroscopy combined with chemometric analysis: A potential point-of-care approach for chronic kidney disease scre... by Kamonchanok Tangwanichgapong, Poramaporn Klanrit, Patutong Chatchawal, Molin Wongwattanakul, Cholatip Pongskul, Rajda Chaichit, Doosadee Hormdee

“…Results: Second derivative spectroscopic analysis of ATR-FTIR spectra revealed distinctive spectral patterns in dried ESRD saliva samples, including characteristic peak shifts observed in both the amide I secondary structures (from 1636 cm-1 in controls to 1629 cm-1 in ESRD) and carbohydrate (from 1037 cm-1 in controls to 1042 cm-1 in ESRD) regions. …”
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Urban pertussis epidemiological patterns in a highly vaccinated megacity: Policy impacts and control strategies in Chongqing, China, 2005-2024 by Rui Shen, Jiawei Xu, Yugang Li, Jianxing Yu, Na Sun, Zilu Xu, Xueying Xu, Xiao Liu, Yang Liu, Bosong Li, Li Qi, Luzhao Feng

“…Methods: Using population-based surveillance data (2005-2024) from Chongqing (population 32.1 million; DTP3 coverage >97%), we conducted hierarchical Bayesian spatial modeling and age-structured Susceptible-Infected-Recovered-Vaccinated transmission analysis. …”
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Genotypic, functional, and phenotypic characterization in CTNNB1 neurodevelopmental syndrome by Nina Žakelj, David Gosar, Špela Miroševič, Stephan J. Sanders, Alicia Ljungdahl, Sayeh Kohani, Shouhe Huang, Lok I Leong, Ying An, Miou-Jing Teo, Fiona Moultrie, Roman Jerala, Duško Lainšček, Vida Forstnerič, Petra Sušjan, Leszek Lisowski, Andrea Perez-Iturralde, Jasna Oražem Mrak, Ho Yin Edwin Chan, Damjan Osredkar

“…In this cross-sectional cohort study, individuals diagnosed with CTNNB1 neurodevelopmental syndrome underwent structured interviews using standardized scales to evaluate motor skills, speech, communication, feeding abilities, visual function, neurodevelopment, and psychopathology. …”
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What Changes are Mandatory in Breast Surgery Training? An International Survey and Recommendations of the French Academy of Surgery and the Senologic International Society by Tolga Ozmen, Caroline Bouche, Megane Buttignol, Bolivar Arboleda-Osorio, Mauricio Magalhaes Costa, Henry Coudane, Darius Dian, Xishan Hao, Shigeru Imoto, Olivier Jardé, Hubert Johanet, Esther Meka, Alexander Mundinger, Ruben Orda, Vahit Ozmen, Tadeusz Pienkowski, Schlomo Schneebaum, Charlotte Vaysse, Susie Brousse, Atilla Soran, Carole Mathelin

“…Evidence shows that structured programs with volume thresholds, multidisciplinary approach, and modern surgical techniques improve patient survival and satisfaction. …”
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Properties of Celery Soluble Dietary Fiber and Its Synergistic Effect with TG Enzyme to Improve Gel Properties of Nemipterus virgatus Unrinsed Surimi by Shengnan TONG, Jinmei WANG, Xingsheng MA, Shumin YI, Xuepeng LI, Jianrong LI, Guangren JI

“…Addressing the issue of poor gelation and easy deterioration of unrinsed surimi, the basic properties (average particle size, solubility, water holding capacity, oil holding capacity, swelling capacity), antioxidant properties (DPPH radical scavenging activity, ·OH scavenging activity, reducing power) and structural properties (infrared spectroscopy, microstructure) of celery soluble dietary fibers (SDF), were determined after extraction. …”
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Quantifying of spatio-temporal variations in the regional gravity field and the effectiveness of earthquake prediction: A case study of MS ≥ 5.0 earthquakes in the Sichuan-Yunnan r... by Weimin Xu, Shi Chen, Yongbo Li, Jiangpei Huang, Bing Zheng, Yufei Han, Zhaohui Chen, Qiuyue Zheng, Hongyan Lu, Linhai Wang, Honglei Li, Dong Liu

“…Reportedly, crustal mass transfer, which is affected by stress state and structural environment, alters the characteristics of the regional gravity field, thus serving as an indicator for locations of moderate to strong earthquakes and a seismology-independent predictor for regions at risk for strong earthquakes. …”
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Comparative analysis of corpus callosum lipidome and transcriptome in schizophrenia and healthy brain by Maria S. Osetrova, Olga I. Efimova, Marina D. Zavolskova, Elena A. Stekolschikova, Gleb N. Vladimirov, Dmitry A. Senko, Tatiana A. Zhuravleva, Anna Y. Morozova, Yana A. Zorkina, Denis S. Andreyuk, George P. Kostyuk, Evgeniy N. Nikolaev, Philipp E. Khaitovich

“…BACKGROUND: Functional and structural studies of the brain highlight the importance of white matter alterations in schizophrenia. …”
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Coaching unified sports: associations between perceived athlete improvement, barriers, and coach attitudes across five European countries by Maciej Wilski, Piotr Urbański, Roxana Ossian, Gabriela Papp Eniko, Nina Bracanovic Milovic, Ivan Radovic, Veronica Sedlackova, Eva Gazova, Nadira Sabanovic, Kada Delic Selimovic, Velibor Srdic, Srboljub Vukovic, Damir Ahmic, Vaiva Abramaviciute, Daiva Dabriliene, Ausra Kriskovieciene, Anna Nadolska

“…Although institutional, social, and logistical barriers to Unified Sports were widely recognized by participants, these factors did not independently predict attitudes once other variables were controlled for.ConclusionThe findings underscore the motivational role of observed progress among athletes with disabilities in shaping coach engagement and suggest that experiential factors such as previous involvement and personal ties may carry unanticipated emotional or structural challenges. These insights point to the importance of designing coach education and support programs that not only promote technical competence but also address emotional resilience and contextual demands. …”
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Innovative strategies for bone organoid: Synergistic application and exploration of advanced technologies by Xu Lou, Qirong Zhou, Zhenglin Dong, Long Bai, Jiacan Su, Hua Yue

“…While 3D bioprinting enhances spatial precision and structural complexity, artificial intelligence accelerates organoid optimization through data-driven approaches. …”
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Exploration of the Possible Relationships Between Gut and Hypothalamic Inflammation and Allopregnanolone: Preclinical Findings in a Post-Finasteride Rat Model by Silvia Diviccaro, Roberto Oleari, Federica Amoruso, Fabrizio Fontana, Lucia Cioffi, Gabriela Chrostek, Vera Abenante, Jacopo Troisi, Anna Cariboni, Silvia Giatti, Roberto Cosimo Melcangi

“…ALLO treatment rescued these parameters in both the colon and hypothalamus but only partially restored mucosal and BBB structural integrity, as well as the NF-κB/PPARγ pathway. …”
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A Comprehensive Study on the Development of an Isotonic Sports Drink Preserved by UV-C Light Assisted by Mild Heat and Loaded with Yerba Mate (<i>Ilex paraguariensis</i> St. Hill.)... by María Luz Kozono, Magdalena Durán Cassiet, Antonella Andreone, Marcela L. Schenk, Sandra N. Guerrero

“…The TEM and SEM micrographs showed that AA evidenced sustained severe structural damage. Furthermore, UV-C/H completely inactivated the native microbiota, while YME incorporation increased the initial aerobic mesophilic and mold-and-yeast populations by 0.48 and 0.70 log cycles, remaining stable during storage. …”
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Investigating the role of environmental factors in the French highly pathogenic avian influenza epizootic in 2022–2023 by Maryem Ben Salem, Mathieu Andraud, Stéphanie Bougeard, Virginie Allain, Morgane Salines, Rodolphe Thomas, Audrey Schmitz, Legrand Saint-Cyr, Karine Fiore, Sophie Le Bouquin, Axelle Scoizec

“…A random forest analysis was further used to hierarchize the relative role of each variable in the clustering process, to assess the importance of the farm structural and environmental conditions on the outbreak occurrence. …”
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HDL from 36-h fasted participants potently promotes efflux of cholesteryl ester from activated microglia by Joanne K. Agus, Oscar M. Muñoz Herrera, Oscar M. Muñoz Herrera, Christopher H. Rhodes, Jack Jingyuan Zheng, Chenghao Zhu, Maurice Wong, Xinyu Tang, Izumi Maezawa, Lee-Way Jin, Carlito B. Lebrilla, Danielle J. Harvey, Angela M. Zivkovic

“…These findings collectively suggest that prolonged fasting induces structural, compositional, and functional alterations in HDL particles, and influences their capacity to attenuate the effects of excess cholesterol and AβO in microglia.…”
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Changes in Temporal and Spatial Patterns of Intrinsic Brain Activity and Functional Connectivity in Upper-Limb Amputees: An fMRI Study by Bingbo Bao, Lei Duan, Haifeng Wei, Pengbo Luo, Hongyi Zhu, Tao Gao, Xiaoer Wei, Jing Li, Yuehua Li, Yimin Chai, Changqing Zhang, Xianyou Zheng

“…The aim of this study was to better understand how local and global structural plasticity in sensory-motor cortical networks changes temporally and spatially after upper-limb amputation. …”
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Effects of light therapy on amygdala connectivity and serotoninergic system in young adults with subthreshold depression by Pan Chen, Guanmao Chen, Guixian Tang, Zibin Yang, Wenhao Ma, Chao Chen, Shilin Sun, Yuan Zhang, Shu Zhang, Zhangzhang Qi, Wenjie Fang, Lijun Jiang, Li Huang, Junxian Ma, Qian Tao, Ying Wang

“…Depression severity was assessed using HAM-D, Centre for Epidemiologic Studies Depression Scale (CES-D) and Beck Depression Inventory (BDI) pre-/post-8-week intervention. Structural/resting-state fMRI scan was conducted. Seed-based static FC (sFC) and dynamic FC (dFC) analyses of the bilateral amygdala and their subfields were conducted.Results Compared to placebo, BLT showed reduced depression scale, and increased sFC of right basolateral amygdala (BLA)/superficial amygdala (SFA)-right middle temporal gyrus (MTG) and dFC of right centralmedial amygdala (CMA) and right inferior orbital frontal gyrus, and decreased sFC of right amygdalostriatal transition/CMA- left thalamus and dFC of right SFA- right medial prefrontal cortex after intervention; while the whole amygdala and its subnuclei volume did not change significantly after BLT. …”
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An Experimental Study of Glycerol Carbonate Synthesis over g-C₃N₄ Catalysts by Mirna Lea Charif, Dragoș Mihael Ciuparu, Ioana Lavinia Lixandru Matei, Gabriel Vasilievici, Ionuț Banu, Marian Băjan, Dorin Bomboș, Cristina Dușescu-Vasile, Iuliana Veronica Ghețiu, Cașen Panaitescu, Rami Doukeh

“…The results indicated that doping significantly enhanced the catalytic performance, most likely due to improved electron charge transfer and structural distortions within the g-C₃N₄ framework. …”
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