Comprehensive analysis of CYP78A family genes reveals the involvement of CYP78A5 and CYP78A10 in fruit development in eggplant by Mengya Zhou, Liying Zhang, Shuangxia Luo, Lijun Song, Shuxing Shen, Jianjun Zhao, Qiang Li, Xueping Chen

“…This classification is consistently supported by their gene structures, domains and conserved motifs. Segmental duplication events were found to contribute to the expansion of the SmCYP78A family. …”
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Deciphering the role of metal ion transport-related genes in T2D pathogenesis and immune cell infiltration via scRNA-seq and machine learning by Zuhui Pu, Zuhui Pu, Tony Bowei Wang, Ying Lu, Ying Lu, Zijing Wu, Zijing Wu, Yuxian Chen, Ziqi Luo, Xinyu Wang, Lisha Mou, Lisha Mou

“…Additionally, we performed a detailed cell-cell communication analysis to identify significant signaling pathways in T2D.ResultsOur analysis identified 1953 DEGs between T2D and ND patients, with the Stepglm[backward] plus GBM model demonstrating high predictive accuracy and identifying 13 hub RMITRGs. Twelve protein structures were predicted using AlphaFold 3, revealing potential functional conformations. …”
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Dead-fallen shrubs improve soil quality and promote herb seedling settlement in an arid sandy land of northern China by Bo Wang, Fei Huang, Rebecca L. Schneider, Stephen J. Morreale, Shaohui Liang, Hongmei Wang, Yulei Ma, Weifeng Liu, Yingge Xie, Gao-Lin Wu, Zhigang Li

“…Regression analysis indicated that seedlings height, density, coverage and biomass were positively correlated with SQI, both in 0–5 cm and 5–10 cm soil. Structural equation modeling revealed that herb seedling settlement at 0–5 cm was driven by physicochemical properties, while at 5–10 cm soil depth relied on physical properties. …”
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Increased vulnerability to psychological distress and suicidal ideation among transgender women with self-reported disabilities in San Francisco, California by Abtin Shafie, Alexis Salvatore, Riley Shea, Eileen Yu, Oyku Ozyucel, Ansharan Akbar, Bow Suprasert, Erin C. Wilson, Willi McFarland, Kelly D. Taylor, Sean Arayasirikul

“…OBJECTIVE: Research among transgender women has found health, but especially mental health, to be shaped by social inequities and multiple, intersectional, structural vulnerabilities. While some studies have shown that transgender adults are also more likely to have a disability than cisgender adults, few studies have explored this intersection. …”
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Clinical profiles and health-related quality of life changes after treatment in advanced colorectal cancer patients: a nationwide study in China by Hongwei Liu, Ziyao Jia, Huifang Xu, Xiaoyang Wang, Hong Wang, Ruihua Kang, Qiong Chen, Xiaoli Guo, Ranran Qie, Mengfei Zhao, Cheng Cheng, Liyang Zheng, Shuzheng Liu, Yin Liu, Shaokai Zhang, China Working Group on Colorectal Cancer Survey

“…The multivariable regressions and structural equation model (SEM) were used to assess the association between characteristics and HRQOL. …”
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Mapping Subalpine Forest Aboveground Biomass in Qilian Mountain National Park Using UAV-LiDAR, GEDI, and Multisource Satellite Data by Yanyun Nian, Siwen Chen, Jie Chen, Minglu Che, Wenhui Zhang, Junejo Sikandar Ali, Hao Zhang, Xingbang Wang, Bingzhi Liao, Xufeng Wang

“…In subalpine forest regions, complex topography and challenging forest inventories introduce significant uncertainties in estimating structural parameters and aboveground biomass. To generate continuous biomass maps over large-scale mountainous forests, it is necessary to extrapolate biomass from sample plots using appropriate models and remote sensing data. …”
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A Comprehensive Description of the Roadmap to Identify and Validate a Myelin Biomarker by Giovanna Capodivento, Davide Visigalli, Andrea Armirotti, Chiara Demichelis, Marinella Carpo, Roberto Fancellu, Erika Schirinzi, Daniele Severi, Diego Franciotta, Fiore Manganelli, Gabriele Siciliano, Alessandro Beronio, Elisabetta Capello, Paola Lanteri, Eduardo Nobile-Orazio, Angelo Schenone, Luana Benedetti, Lucilla Nobbio

“…Given that myelin is enriched in specific lipids and proteins, it is reasonable they could represent eligible candidates as structural damage biomarkers for this characteristic membrane. …”
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Repositioning FDA-Approved Sulfonamide-Based Drugs as Potential Carbonic Anhydrase Inhibitors in <i>Trypanosoma cruzi</i>: Virtual Screening and In Vitro Studies by Eyra Ortiz-Pérez, Adriana Moreno-Rodríguez, Timoteo Delgado-Maldonado, Jessica L. Ortega-Balleza, Alonzo González-González, Alma D. Paz-González, Karina Vázquez, Guadalupe Avalos-Navarro, Simone Giovannuzzi, Claudiu T. Supuran, Gildardo Rivera

“…Future studies should focus on structural modifications to improve selectivity. Integrating docking, parasitological, and enzymatic data is crucial for optimizing drug candidates for Chagas disease.…”
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Predicting leakage of the VERCORS mock-up and concrete containment buildings - a digital twin approach by Laurent Charpin, Jessica Haelewyn, Anass Cherki El Idrissi, Julien Niepceron, Benoît Masson, Charles Toulemonde, Guillaume Boulant, Jean-Philippe Mathieu, François Hamon, Sylvie Michel-Ponnelle, Jean-Marie Hénault, Frédéric Taillade, Jean-Luc Adia, Florian Escoffier

“…An important numerical effort has also been made to implement structural computations of the mock-up and to capitalize these computations as well as their post-processing (so as to compare automatically with the monitoring data) in what can be called a digital twin of the mock-up. …”
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Seasonal drought shapes the relationship between stem CO2 efflux and belowground respiration in an even-age rubber plantation on Hainan Island, China by Xinwei Guo, Bo Song, Rui Sun, Rui Sun, Guoyu Lan, Guoyu Lan, Bangqian Chen, Bangqian Chen, Chuan Yang, Chuan Yang, Zhixiang Wu, Zhixiang Wu

“…Consequently, Ec in both tapped and non-tapped rubber trees displayed an overall single-peak pattern, with significantly lower values during the dry season compared to the wet season, suggesting growth phenology primarily regulates Ec seasonal dynamics. Structural equation modeling revealed that root respiration (Rroot), sap flow flux density (Fd), and soil moisture at 50 cm depth as the primary drivers of the Ec variations during the dry season. …”
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Exploring the G-Quadruplex Formation of AS1411 Derivatives by Pedro Lourenço, David Moreira, André Miranda, Jéssica Lopes-Nunes, Izamara Maocha, Tiago Santos, Pedro L. Ferreira, Fani Sousa, Artur Paiva, Carla Cruz

“…In silico studies reveal structural insights and demonstrate that AS1411 derivatives interact with NCL, establishing multiple interactions with the different domains, thereby further supporting the experimental findings. …”
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A comprehensive phenotypic and genotypic taxonomic review of Leishmania (Leishmania) poncei n. sp. (Kinetoplastea: Trypanosomatidae): a novel agent of cutaneous (non-ulcerated) and... by Fernando Tobias Silveira, Gabriela V. Araujo Flores, Carmen Maria S. Pacheco, Wilfredo Sosa-Ochoa, Thiago Vasconcelos dos Santos, Edivaldo Costa Sousa, Concepción Zúniga Valeriano, Vania Lucia da Matta, Claudia Maria C. Gomes, Patrícia Karla Ramos, Luciana Vieira Lima, Marliane Batista Campos, Carlos Eduardo P. Corbett, Márcia Dalastra Laurenti

“…Molecular findings showed that the Honduran parasite is more ancestral than all known viscerotropic Leishmania species, exhibited an unprecedented structural variation on chromosome 17 with the highest frequency of genomic SNPs, formed a distinct phylogenetic lineage, and displayed a homozygous SNP profile typical of a parental (non-hybrid) parasite. …”
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Tailoring color and antibacterial properties of cotton fabric materials using gold nanoparticles synthesized from Mangifera indica peel extract by Jared Deve P. Delicana, Aldrin R. Lalem, Jay C. Dulog, Ryan M. Lumod, Rolen Brian P. Rivera, Noel Lito Sayson, Gerard Dumancas, Rey Y. Capangpangan, Arnold A. Lubguban, Noel Peter B. Tan, Joe Anthony H. Manzano, Mario A. Tan, Romnick B. Unabia, Jahor L. Omping, Arnold C. Alguno

“…AuNPs were synthesized at different concentrations, producing various colors, and were successfully used to dye cotton threads via a heating method. The structural and optical properties of AuNPs were investigated by Fourier transform infrared (FTIR) spectroscopy, scanning electron microscope (SEM), transmission electron microscope (TEM), ultraviolet–visible spectrophotometer (UV–Vis) and dynamic light scattering (DLS). …”
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Real-time and resource-efficient banana bunch detection and localization with YOLO-BRFB on edge devices by Shuo Wang, Shuo Wang, Shuo Wang, Lijiao Wei, Danran Zhang, Danran Zhang, Ling Chen, Ling Chen, Weihua Huang, Dongjie Du, Kangmin Lin, Zhenhui Zheng, Zhenhui Zheng, Zhenhui Zheng, Jieli Duan

“…Current methods face challenges in achieving high detection accuracy and efficient deployment due to their structural complexity and significant computational demands. …”
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Effective binding sufficiently-small SiO2 nanoparticles within carbon nanosheets framework enables a high-performing and durable anode for lithium-ion batteries by Zhefei Sun, Zhiwen Zhang, Shenghui Zhou, Weicheng Liu, Jianhui Liu, Quanzhi Yin, Jianhai Pan, Xiaoyu Wu, Zilong Zhuang, Dong-Liang Peng, Qiaobao Zhang

“…In-situ transmission electron microscopy and ex-situ microscopic and spectroscopic analyses reveal moderate volume variation and exceptional structural stability during cycling, supported by the formation of a robust solid-electrolyte interphase that underpins its long-lasting performance. …”
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Breaking Staphylococcus aureus biofilms with the antimicrobial lipopeptide humimycin and its synthetic analogs by Md Ramim Tanver Rahman, Florence Henley, Ismail Fliss, Eric Biron

“…In this study, humimycin A 1 and five structural analogs (2-6) were synthesized via solid-phase peptide synthesis and evaluated for antimicrobial and antibiofilm activity against S. aureus ATCC 29213. …”
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Transmission of human herpesvirus-8 through liver transplantation and development of post-transplantation Kaposi sarcoma: A case report by Julius Leander Ross Clemmesen, Nicoline Arentoft, Nicolai Aagaard Schultz, Moises Alberto Suarez-Zdunek, Annika Loft, Nikolai Kirkby, Jens Georg Hillingsø, Gro Linno Willemoe, Michael Perch, Christian Ross Pedersen, Susanne Dam Nielsen

“…Kaposi sarcoma was successfully treated with reduction of immunosuppressive treatment and conversion from tacrolimus to everolimus, resulting in viral clearance and complete metabolic and structural tumour response. A review of the donor post-transplantation revealed multiple risk factors for being infected with HHV-8, with subsequent analysis confirming the donor was positive for HHV-8. …”
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Isolation, characterization, and biomedical potential of phycoerythrin phycobiliprotein from Kappaphycus alvarezii (Doty) L. M. Liao: antimicrobial, antioxidant, and anticancer act... by Harinathan Balasundaram, Parthasarathy Seethapathy, Subbiah Sankaralingam, Shunmugiah Mahendran, Murugan Mareeswaran, Jeyaraj Pandiarajan, Pandiaraj Maheswari, Sakthivel Venkatesh, Malaisamy Arunkumar, Girish R. Pathade, Deepu Pandita, Anu Pandita, Fazal Ullah, Hosam O. Elansary, Muhammad Nazim, Adel A. Fickak, Mohamed A. Rashwan, Ihab Mohamed Moussa

“…The phycoerythrin extract from K. alvarezii demonstrated potent antimicrobial, antioxidant, and anticancer properties, with significant cytotoxicity against lung cancer cells and confirmed apoptosis induction. Structural analysis revealed its bioactive composition, emphasizing its potential as a natural therapeutic agent. …”
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Chronic cerebral hypoperfusion induces venous dysfunction via EPAS1 regulation in mice by Vanessa Kristina Wazny, Aparna Mahadevan, Nhi Nguyen, Hannah Wee, Ashwati Vipin, Tammy Lam, Kai Yi Tay, Jia-Xiang See, Gurveen Sandhu, Yi Jin Leow, Giuseppe D’Agostino, Martin Graf, Aravind Sivakumar, Sichen Lin, Nguyen Cao Thien Phuc, James Xiao Yuan Chen, Sarah R. Langley, Lay Teng Ang, Kyle M. Loh, Nagaendran Kandiah, George J. Augustine, Christine Cheung

“…Through imaging and single-cell transcriptomics of the mouse cortex, we uncover that blood vessel venous cells undergo maladaptive structural changes associated with increased Epas1 expression and activation of developmental angiogenic pathways. …”
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Tuning the Crystalline Phase Transition Temperature of 1T‐TaS2 via Surface Oxidation by Lilin Yang, Shihao Hu, Genyu Hu, Weikang Zhou, Yubo Zhang, Tianyu Dai, Yun Zhang, Jinfeng Zhang, Chen Liu, Jia‐Ou Wang, Jingsi Qiao, Zhilin Li, Yan Shao, Xu Wu

“…The phase transition temperature, corresponding to the stability of the atomic structural phase, is one of the key parameters in the phase engineering study. …”
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