Do Long-Acting Injectable Antipsychotics Influence Serum Levels of Brain-Derived Neurotrophic Factor in People With Schizophrenia and Schizoaffective Disorder? by Mirko Manchia, Ulker Isayeva, Roberto Collu, Diego Primavera, Luca Deriu, Edoardo Caboni, Maria Novella Iaselli, Davide Sundas, Massimo Tusconi, Clement C. Zai, Maria Scherma, Alessio Squassina, Donatella Congiu, Pasquale Paribello, Federica Pinna, Claudia Pisanu, Anna Meloni, Walter Fratta, Paola Fadda, Bernardo Carpiniello

“…Four tag single nucleotide polymorphisms (SNPs) within the BDNF gene (rs1519480, rs11030104, rs6265 [Val66Met], and rs7934165) were selected using standard parameters and analyzed with polymerase chain reaction (PCR). Mixed-effects linear regression models (MLRMs) were used to analyze longitudinal data. …”
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Worsening of Controlled Attenuation Parameter and Metabolic Profile After HCV Cure in People with HIV as a Sign of Steatosis by Alessia Siribelli, Sara Diotallevi, Laura Galli, Camilla Muccini, Giulia Morsica, Riccardo Lolatto, Tommaso Clemente, Emanuela Messina, Costanza Bertoni, Caterina Uberti-Foppa, Antonella Castagna, Hamid Hasson

“…Univariate and multivariate mixed linear models were calculated to estimate crude mean changes in CAP, metabolic parameters, and weight; slopes were reported with the corresponding 95% confidence intervals (95% CI). …”
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Traumatic brain injury and anger proneness: results from the Atherosclerosis Risk in Communities (ARIC) study by Connor A. Law, Holly Elser, Alexa E. Walter, Thomas H. Mosley, Keenan Walker, Rebecca F. Gottesman, Andrea L. C. Schneider, Andrea L. C. Schneider

“…We performed 3 analyses: cross-sectional associations of prior TBI with anger proneness (Visit 2, 1990–1992, N = 13,694), associations of interval TBI with change in anger proneness (Visit 2, 1990–1992 to Visit 4, 1996–1998, N = 9,022), and prospective associations of baseline anger proneness with incident TBI (Visit 2, 1990–1992 to 12/31/2020, N = 11,713). Adjusted Tobit, linear, and Cox-proportional hazards regression models estimated associations, respectively.ResultsOverall, participants were a mean age of 57 years at Visit 2, 55% were female, and 24% were Black. …”
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Effect of Short‐Term Exposure to Ambient Temperatures on Parkinson's Diseases Mortality Among Elderly Aged 60 Years and Above in China, 2013–2020 by Rui Zhang, Ainan Jia, Huan Zheng, Yonghong Li, Chaonan Wang, Siyuan Wu, Songwang Wang, Qing Guo, Yu Wang, Peng Bi, Jing Wu

“…A combination of conditional logistic regression and distributed lag non‐linear model was employed to analyze the data, and the mortality burden attributed to ambient temperatures was quantified. …”
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Sex differences in proteomics of cardiovascular disease – Results from the Yale-CMD registry by Yihan Liu, Zuoheng Wang, Sean P. Collins, Jeffery Testani, Basmah Safdar

“…Differential protein expression was assessed using linear regression models, adjusting for age, race, body mass index, diabetes, dyslipidemia, hypertension, or smoking. …”
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Future Habitat Shifts and Economic Implications for Ophiocordyceps sinensis Under Climate Change by Liangliang Chen, Hongfen Teng, Songchao Chen, Yin Zhou, Dan Wan, Zhou Shi

“…This study utilizes a comprehensive dataset on O. sinensis occurrences and employs a multi‐model approach (constructed by Classification Tree Analysis [CTA], Flexible Discriminant Analysis [FDA], Generalized Boosted Model [GBM], Generalized Linear Models [GLM], Multivariate Adaptive Regression Splines [MARS], Random Forest [RF], and MaxEnt models) to simulate its potential suitable habitat distribution on the TP under current and future climate change scenarios (SSP1‐2.6 and SSP5‐8.5). …”
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Profiling of Circulating Cell-free DNA Methylation Patterns Identifies Aberrant Methylated CTBP1 Promotor Sites for Prediction of Alzheimer’s Disease by Zhiwu Dong, Kewen Zhao, Hongjun Gu, Wenwei Yang, Xin Zhang

“…Methods: The Illumina Infinium array was utilized to detect the methylation patterns of circulating cell-free DNA from AD patients and healthy controls. The R Bioconductor Linear Models for Microarray Data (LIMMA) package was employed to identify methylation variable positions (MVPs), and Probe Lasso was used to pinpoint differentially methylated regions (DMRs) linked to AD. …”
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Applications of Advanced Imaging for Radiotherapy Planning and Response Assessment in the Central Nervous System by Liam S. P. Lawrence, Rachel W. Chan, Amit Singnurkar, Jay Detsky, Chris Heyn, Pejman J. Maralani, Hany Soliman, Greg J. Stanisz, Arjun Sahgal, Angus Z. Lau

“…Methods: Recent articles were selected for discussion, covering the following topics: advanced imaging on MRI-linear accelerators for early response assessment in glioma; PET for guiding treatment planning and response assessment in glioma; and contrast-enhanced imaging and metabolic imaging for differentiating tumor progression and radiation necrosis for brain metastasis treatment. …”
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Violence and harassment against healthcare workers: a psychological-clinical perspective on a survey in a Policlinic Hospital by Ermanno Vitale, Francesca Vella, Serena Matera, Silvia Mazzeo, Chiara Farrauto, Veronica Filetti, Venerando Rapisarda, Venerando Rapisarda, Giorgia Farruggio, Noemi Maria Vitale, Eleonora Uccelli, Abdulnaser Fakhrou, Lucia Rapisarda, Giorgio Bertolazzi, Davide Matera, Pasquale Caponnetto, Pasquale Caponnetto

“…Statistical analyses included descriptive statistics, linear regression and ANOVA (p < 0.05).Results27% of HCWs reported experiencing at least one form of WPV in the past 12 months. …”
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Oral enzyme combination therapy reduces systemic inflammation, urinary CTXII and pain in knee osteoarthritis: a proof-of-mechanism, randomised, crossover, double-blind, placebo-con... by Thomas Pap, Odd Erik Johansen, Yves Henrotin, Valérie Badot, Stefanie Rau, Maximilian von Eynatten, Jean-Emile Dubuc, Siddhartha Lieten, Didier Urbin-Choffray, Karl Brabants

“…Data from the modified intention-to-treat population (mITT) were analysed using a generalised linear mixed model. No correction for multiple comparisons was made due to the exploratory nature of the study.Results Altogether, 45 patients were randomised; 43 completed both treatment sequences (mITT; mean age: 63.3 years; mean BMI: 27.4 kg/m2; mean global Knee injury and Osteoarthritis Outcome Score (KOOS): 48.7). …”
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Health in Spanish older people: Dietary habits, lifestyles and related socioeconomic factors by Elisa Amo-Saus, Isabel Pardo-García, Ana Pilar Martínez-Valero, Francisco Escribano-Sotos

“…Methods: To estimate diet quality, we used the Healthy Eating Index for Spanish Population (IASE). A multiple linear regression analysis (regression coefficients and 95 % CIs) was used to determine the relationship between socio-demographic, health and lifestyle factors and IASE. …”
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Cesarean section diverticulum area predicting the intraoperative hemorrhage at suction curettage for cesarean scar pregnancy after focused ultrasound ablation surgery by Jun-rong Huang, Li-ya Sun, Ying Tang, Ming-bo Wen, Ming-tao Yang, Fan Xu, Qiuling Shi, Hui-quan Hu

“…The ROC curve was plotted to identify the optimal cutoff values.Results The median CSD area size in Group 3 (336.8 mm2) was significantly greater than in Groups 1 (128.6 mm2) and 2 (121.6 mm2) (p < .05). Using multiple linear regression analysis, CSD area was associated with intraoperative blood loss (p < .05). …”
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Spatial Variation and Uncertainty Analysis of Black Sea Level Change from Virtual Altimetry Stations over 1993–2020 by Yuxuan Fan, Shunqiang Hu, Xiwen Sun, Xiaoxing He, Jianhao Zhang, Wei Jin, Yu Liao

“…The results show that sea level changes are non-linear over time and exhibit spatial variability in the Black Sea. …”
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Effects of taxane-anthracycline and taxane only treatment on cardiac function in breast cancer—a retrospective cohort study by Árpád Kézdi, Emese Szelke, Magdolna Dank, Dorottya Mühl, Gyöngyvér Szentmártoni, Gergely Szabó, Dominic Joseph Fogarasi, István Takács, Viktor J Horváth, Ádám G Tabák

“…Trajectories of ejection fraction and diastolic function associated markers over the follow-up periods were analysed by linear mixed models. Results Mean age of the anthracycline plus taxane group was 52.7 ± 14.1 years, of the single taxane group 55.2 ± 13.1 years. …”
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A Randomized, Placebo-Controlled, Double-Blind Trial to Assess the Effects of <i>Apocynum venetum</i> L. (<i>A. venetum</i>) Venetron^® on Sleep and Stress in Those Expre... by Kaitlyn P. White, Susan Hewlings, Corey Bryant, Megan Moseley, Christopher R. D’Adamo, Christopher S. Colwell, Jeff Chen, Emily K. Pauli

“…Perceived stress, sleep quality, and cognitive function were evaluated at baseline and weekly using validated assessments. A linear mixed-effects regression model was used to compare the change in health outcome scores between active and placebo groups. …”
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Anatomic and Functional Outcomes of Lamellar Macular Hole and Epiretinal Membrane Foveoschisis Surgery: Predictive Factors and Associated Complications &mdash; A Retrospective Inte... by Er-reguyeg Y, Doukkali S, Hébert M, You EL, Bourgault S, Caissie M, Tourville É, Dirani A

“…Variables associated with final BCVA were assessed using a multiple linear regression model.Results: 51 subjects presented with ERMF, while 39 presented with LMH. …”
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Green tea silver nanoparticles improve physiological motor and cognitive function in BALB/c mice during inflammation by Herbert Izo, Ninsiima, Ejike, Daniel Eze, Kenneth, Ssekatawa, Halima, Nalugo, Caroline, Asekenye, David, Onanyang, Edson Ireeta, Munanura, Moses, Ariong, Kevin, Matama, Gerald, Zirintunda, Ngala Elvis, Mbiydzenyuy, Fred, Ssempijja, Adam Moyosore, Afodun, Ibe Michael, Usman, Oscar Hilary, Asiimwe, Julius, Tibyangye, Keneth Iceland, Kasozi

“…Hypersensitivity was measured through the temperature sensation experiment and a non-linear regression analysis was done. Here, synthesized green tea AgNPs registered anabsorbance band at 460 nm, phytochemicals due to presence of organic functional groups of O––C––O of oxycarbons, of C––C of a conjugate alkene, C––O of a stretching bond of a secondary alcohol. …”
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Investigating the cost of mechanized unpaved road maintenance operations in Uganda by Obeti, Andrew Moses, Byaruhanga, Chris Bic, Muhwezi, Lawrence, Kakitahi, John Muhumuza

“…A USD to Ugx conversion rate of 3,800 was used. Two linear regression cost models with a 0.679 and 0.687 R 2 value were computed, and these can be used in preliminary road maintenance cost prediction. …”
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463 Identification of molecular and cellular events during recurrence of focal segmental glomerulosclerosis in human allografts by Haseeb Zubair, Thomas V Rousselle, Amol C Shetty, Azim Shafquat, Akalin Enver, Manish Talwar, Daniel G Maluf, Gallon Lorenzo, Valeria R Mas

“…Our findings reveal that podocyte detachment is driven by metabolic and structural dysregulation rather than cell death, increasing VEGFA expression and disrupting glomerular endothelial cell growth and permeability. …”
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Cyanide in cassava: unveiling health risks in the lens of unsustainable food systems in Sub-Saharan Africa – a systematic review by Gareth Osman, Wyson Maleta, Kingsley Masamba, Tinna Ng'ong'ola-Manani, Alexander A. Kalimbira

“…This systematic review synthesizes evidence on the health impacts of cyanide exposure from cassava consumption in SSA and examines how these risks are shaped by structural vulnerabilities in food systems.MethodsA comprehensive literature search was conducted across four databases: PubMed, Scopus, JSTOR, and AJOL. …”
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