Serologic biomarker discovery for differentiating Lyme disease from diseases with similar clinical symptoms using broad profiling of antibody binding by Tingting Zhang, Laurie Baert, Neal W. Woodbury, Laimonas Kelbauskas, Laimonas Kelbauskas

“…A combination of antibody binding to a library of linear, diverse peptides and machine learning methods revealed a panel of biomarker proteins from the proteome of the Borrelia burgdorferi bacterium (LD causing pathogen) that can be used to differentiate between LD and other diseases.ResultsA subset of the biomarkers was independently validated and demonstrated to show robust differentiating power. …”
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The Secular Evolution of Planetary Nebula IC 418 and Its Implications for Carbon Star Formation by Albert A. Zijlstra, Quentin A. Parker

“…In this Letter we provide direct evidence for such a case. A secular, linear, factor of ∼2.5 increase is found in the strength of the [O iii ] lines relative to H β over an 130 yr period in the young, well-known, low-excitation planetary nebula IC 418. …”
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Prognostic Survival Analysis for AD Diagnosis and Progression Using MRI Data: An AI-Based Approach by T. Deenadayalan, S. P. Shantharajah

“…By integrating survival analysis with deep learning, the framework addresses limitations in previous work, such as reliance on linear assumptions and limited classification capabilities, and provides actionable insights for clinical workflows, supporting personalized treatment and early intervention strategies. …”
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Walking cadence as a measure of activity intensity and impact on functional capacity for prefrail and frail older adults. by Daniel S Rubin, Anthony Hung, Emi Yamamoto, Donald Hedeker, David E Conroy, Megan Huisingh-Scheetz, Jennifer S Brach, Nancy W Glynn, Margaret K Danilovich

“…Our primary outcome was improvement in 6-minute walk test distance above the minimally clinical important difference. We performed linear and logistic mixed-effects regressions to analyze our aims. 102 participants were included in the final analysis with 56 in the CSW group and 46 in the HIW group. …”
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Productivity and quality of Mombasa grass under fertilization with pig deep-litter and NPK by Marina da C. Guerrero, Tiago R. de Sousa, Saulo A. de Oliveira, Rômulo R. Caldeira, Adilson Pelá

“…PDL doses associated with mineral fertilization led to linear increases from 52 to 282% in the analyzed variables and better bromatological composition. …”
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HUBUNGAN ANTARA ASUPAN KARBOHIDRAT DENGAN PROFIL LIPID PADA PASIEN PENYAKIT JANTUNG KORONER by Risky Wijaya Utami, Sefri Noventi Sofia, Etisa Adi Murbawani

“…Uji bivariat menggunakan uji korelasi Pearson, Independent sampel T-test dan One way anova, sedangkan untuk uji multivariat menggunakan uji regresi linear. Hasil: Uji korelasi Pearson untuk hubungan antara asupan karbohidrat dengan profil lipid (kolesterol total, kolesterol HDL, kolesterol LDL, dan trigliserida) menunjukkan nilai p sebesar 0,051; 0,771; 0,106; 0,143 yang menyatakan bahwa tidak ada hubungan bermakna antara asupan karbohidrat dengan profil lipid. …”
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Internalized stigma mediates the relationship between pelvic pain severity and both depression and anxiety in women with chronic pelvic pain by Sarah E. Francis, Jamey T. Brumbaugh, Jeongwi An, Emily J. Bartley, Daniel W. McNeil

“…Methods: A sample of 241 adult women with CPP from the United States completed a series of questionnaires via an online survey. Hierarchical linear regression models and moderation analyses were used to determine associations among the variables of interest (i.e., CPP, depression, anxiety sensitivity, and internalized stigma). …”
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Concentrating solar power technology in Bangladesh: Potential and challenges for large-scale implementation by Md. Abdu Rabbir Rasul, Nafeem Yasar, Nahid-Ur-Rahman Chowdhury

“…Utilizing the System Advisor Model (SAM) software, a thorough analysis of the technical and economic aspects of implementing a 50 MW Parabolic Trough CSP Plant, Linear Fresnel CSP Plant, and the Solar Power Tower CSP Plant in the districts of Munshiganj, Sunamganj, Dinajpur, Cox’s Bazar, and Pabna was conducted. …”
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Association between hearing loss and insulin resistance as measured by metabolic score for insulin resistance in NHANES 1999 to 2018 by Lingxin Wu, Huifen Yang, Zhaoran Ding, Qingqing He

“…Individuals with METS-IR in the highest tertile had higher risks of SFHL with OR of 1.814 (95% CI: 1.180–2.790) than those in the lowest tertile. Linear relationships were found between METS-IR and sensorineural HL. …”
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LOCAL/GLOBAL RELATIONS OF THE ENVIRONMENTAL DIMENSION IN THE ACADEMIC VIEW by Julia Marques dos Santos, Liliana Angel Vargas

“…Conclusão: Esta pesquisa nos permite afirmar que a reflexão aqui proposta é ainda periférica dentro do processo de formação dos futuros profissionais de enfermagem, que abordam a questão de forma pontual e linear. No entanto, entendemos que a intrínseca relação entre o global e o local torna fundamental uma leitura integral destes aspectos, em cuja interseção se expressa o processo saúde-doença em diversas escalas territoriais.…”
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Association between prescription medication and erectile dysfunction: results from NHANES dataset and mendelian randomization study by Jian Cai, Juan Zhao, Hao Tan, Hang Yang

“…Multivariable generalized linear models (GLM) and weighted logistic regression were employed to evaluate the relationship between prescription medication use and ED. …”
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Ontogeny of Toll-like receptor mediated cytokine responses of human blood mononuclear cells. by Nathan P Corbett, Darren Blimkie, Kevin C Ho, Bing Cai, Darren P Sutherland, Arlene Kallos, Juliet Crabtree, Annie Rein-Weston, Pascal M Lavoie, Stuart E Turvey, Natalie R Hawkins, Steven G Self, Christopher B Wilson, Adeline M Hajjar, Edgardo S Fortuno, Tobias R Kollmann

“…Our data contradict the notion of a linear progression from an 'immature' neonatal to a 'mature' adult pattern, but instead indicate the existence of qualitative and quantitative age-specific changes in innate immune reactivity in response to TLR stimulation.…”
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Factors associated with nursing students’ satisfaction with simulation-based assessments: interaction between psychological safety and gender in a cross-sectional study by Minjung Kyung, Hieun Kim, Jung-Hee Kim

“…Based on the NLN/Jeffries Simulation Framework, multiple linear regression was employed to analyze the relationships between satisfaction in SBL and variables such as demographics, psychological safety, and simulation design features. …”
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An innovative method to determine the stress-dependency of Poisson’s ratio of granitic rocks by Samad Narimani, László Kovács, Balázs Vásárhelyi

“…Additionally, the Poisson’s rate follows a linear increase with stress, up to the point of unstable crack propagation stress. …”
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Participatory science methods to monitor water quality and ground truth remote sensing of the Chesapeake Bay. by Patrick Neale, Shelby Brown, Tara Sill, Alison Cawood, Maria Tzortziou, Jieun Park, Min-Sun Lee, Beth Paquette

“…In validation samples, HydroColor turbidity and Aquafluor in vivo chlorophyll and CDOM fluorescence were linear estimators of standard analytical measures of turbidity, chlorophyll and CDOM, respectively, with R2 values ranging from 0.65 to 0.85. …”
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Application of Repetitive Control to Grid-Forming Converters in Centralized AC Microgrids by Hélio Marcos André Antunes, Ramon Ravani Del Piero, Sidelmo Magalhães Silva

“…Additionally, the proposed control was implemented on a Texas Instruments TMS320F28335 digital signal processor and validated through hardware-in-the-loop (HIL) simulation using the Typhoon HIL 600 platform, considering multiple scenarios with both linear and nonlinear loads. The main results highlight that the RC improves voltage regulation, mitigates harmonic distortion, and increases power delivery capability, thus validating its effectiveness for GFC operation.…”
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Determining Body Condition of Dairy Cows for Early Diagnosis of Physiological Diseases by D. Yu. Pavkin, S. S. Yurochka, A. A. Polikanova, I. M. Dovlatov

“…(Results and discussion) The sample and the dependence are proved to be representative as the Pearson correlation coefficient equals R=0.849, which shows a strong linear relationship between the body condition score and live weight. …”
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Home settings are associated with less functional decline among older adults compared to community-care foster homes and skilled nursing facilities in Hawaii. by Hua Zan, Yanyan Wu, Yan Luo, John P Barile, Joshua R Holmes, Joy Agner

“…To increase comparability despite these differences, we matched older adults (n = 852) on baseline functional status, age, sex, marital status, and race/ethnicity using propensity score matching and performed sensitivity analyses on cognitive status. After matching, linear mixed-effects modeling revealed a notably slower rate of functional decline at home compared to nursing homes or foster homes. …”
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Effect of radiobiological parameters on the TCP for breast cancer radiotherapy by Luany Nobre Furlan, Mairon Marques dos Santos, Thatiane Alves Pianoschi

“…These parameters informed the calculation of the fraction of cells surviving irradiation via the linear-quadratic model, facilitating an assessment of treatment efficacy through the Poissonian TCP model. …”
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Outer Macular Microvascular Supply in Retinitis Pigmentosa Examined using Optical Coherence Tomography Angiography by Mingsheng Hong, Jiquan Wen, Jixian Lou, Jiehui Xu, Tingjun Xu

“…The DCP was significantly reduced in the parafovea region between the macular intact and defect groups P<0.05, except in the fovea and nasal regions. After linear regression, the DCP/SCP ratio in the whole, fovea, and parafovea regions was closely related to the DCP vessel density P<0.05, and CRT in the fovea and parafovea was not related to the whole DCP (P=0.186 and P=0.539). …”
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