Single-chamber pacemakers: with or without leads? Cost-effectiveness and cost-utility analyses by José Ramón Lago-Quinteiro, Francisco Reyes-Santias, Manel Antelo, Vicent Caballer-Tarazona, José Luis Martinez-Sande, Javier Garcia-Seara, Moisés Rodriguez-Manero, Jose Ramon Gonzalez-Juanatey

“…Introduction The evolution in pacemaker technologies has led to improvements in size, weight, functionality, and durability, even as the battery and electrode-based structural configuration has remained essentially the same.Objective To compare the cost-effectiveness and cost-utility of conventional and leadless pacemakers.Material and methods We conducted a retrospective observational study of 403 patients randomly implanted with a conventional or leadless pacemaker (1 June 2015–31 January 2020) in the Hospital-University Complex of Santiago de Compostela (Galicia, NW Spain).Results Conventional and leadless pacemakers were implanted in 244 and 159 patients, respectively. …”
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Design, Development, and Testing of a Compact Underwater ROV for Inspection and Exploration by Mohd Shahrieel Mohd Aras, Teoh Yi Xin, Fauzal Naim Zohedi, Mohd Bazli Bahar, Mohamad Haniff Harun, Alias Khamis, Zairi Ismael Rizman

“…The ROV is designed using Fusion 360 software, with finite element analysis (FEA) ensuring structural integrity under underwater pressure. Key performance metrics, including buoyancy, acceleration, velocity, and stability, are evaluated to validate the system's operation. …”
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Modular synthesis of CF2-containing compounds with PhSO2CF2H reagent through difluoromethylene radical anion synthon strategy by Shuo Sun, Rulong Jia, Xin Zhou, Zhongyi Wang, Jian Rong, Chuanfa Ni, Jinbo Hu

“…The generation of radicals (•CF2R) via visible light-promoted homolytic cleavage of C−S bonds in (phenylsulfonyl)difluoromethylated derivatives (PhSO2CF2R) is the linchpin in the diFRAS strategy to construct gem-difluorides (R1-CF2-R2) with structural complexity.…”
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Analyzing the impact of fear of missing out on the psychological well-being of students in Ho Chi Minh City by Ngô Thị Kim Phượng, Lê Xuân Tùng, Nguyễn Thúy Lan Anh, Phạm Minh

“…Partial Least Squares Structural Equation Modeling (PLS-SEM) showed that FoMO reduces individuals’ psychological well-being. …”
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The complete chloroplast genome of Oxytropis monophylla (Fabaceae): insights into genome features and evolutionary relationships by Chaopan Zhang, Shenglin Zhao, Almira Ablat, Xiaodong Ding, Wenchao Hu

“…The results showed that the O. monophylla cp genome exhibited atypical structural characteristics due to the absence of an IR region. …”
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The main protease (Mpro) from SARS-CoV-2 triggers plasma clotting in vitro by activating coagulation factors VII and FXII by Anna Pagotto, Federico Uliana, Elena Cavedon, Giulia Nordio, Andrea Pierangelini, Laura Acquasaliente, Maria Ludovica Macchia, Massimo Bellanda, Barbara Gatto, Giustina De Silvestro, Piero Marson, Dario Gregori, Paolo Simioni, Paola Picotti, Vincenzo De Filippis

“…Overall, integrating biochemical, proteomics and structural biology experiments, we unveil a novel mechanism linking SARS-CoV-2 infection to thrombotic complications in COVID-19.…”
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Variants of RBM20 gene in pediatric patients with dilated cardiomyopathy by A. M. Kiselev, T. L. Vershinina, S. I. Tarnovskaya, E. V. Yakovleva, L. Butish, Yu. V. Fomicheva, P. A. Fedotov, A. A. Kozyreva, Yu. A. Vakhrushev, A. K. Latypov, A. А. Morozov, I. A. Kozyrev, T. M. Pervunina, E. S. Vasichkina, A. A. Kostareva

“…Three cases of childhood DCMP development, associated with structural disorders in the RBM20 gene, are particularly described. …”
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Phase-transfer-catalyst enabled enantioselective C–N coupling to access chiral boron-stereogenic BODIPYs by Xue-Qing Zhang, Xiao-Juan Lv, Luying Guo, Juan Ma, Bin Su, Yuefei Hu, Lijuan Jiao, Zhong-Yuan Li, Erhong Hao

“…Chiral BODIPYs have attracted increasing attention owing to not only their distinctively photophysical properties and applications in circularly polarized luminescence (CPL) materials, but also diversely structural modification. In this·work, we present a phase-transfer-catalyst enabled enantioselective C–N coupling reaction of BODIPYs with diverse nucleophiles. …”
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Multiscale computational framework linking alloy composition to microstructure evolution via machine learning and nanoscale analysis by Jaemin Wang, Hyeonseok Kwon, Sang-Ho Oh, Jae Heung Lee, Dae Won Yun, Hyungsoo Lee, Seong-Moon Seo, Young-Soo Yoo, Hi Won Jeong, Hyoung Seop Kim, Byeong-Joo Lee

“…Abstract Achieving targeted microstructures through composition design is a core challenge in developing structural materials for high-performance applications. …”
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Neural propensity for trait rumination in adolescents: A cross-sectional study with Voxel-Based Morphometry by Diane Joss, Anna O. Tierney, Kristina Pidvirny, Nigel M. Jaffe, Hannah Goodman, Nicholas J. Carson, Zev Schuman-Olivier, Christian A. Webb

“…Despite prior research on the neuroscience of rumination in adults, more research is needed regarding the underlying structural neural correlates associated with adolescent rumination. …”
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The disordered p53 transactivation domain is the target of FOXO4 and the senolytic compound FOXO4-DRI by Benjamin Bourgeois, Emil Spreitzer, Daniel Platero-Rochart, Margret Paar, Qishun Zhou, Sinem Usluer, Peter L. J. de Keizer, Boudewijn M. T. Burgering, Pedro A. Sánchez-Murcia, Tobias Madl

“…Here, we solve the solution NMR structural models of the p53 transactivation domain in complex with the FOXO4 forkhead domain and in complex with FOXO4-DRI. …”
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Matrix-induced nuclear remodeling and mechano-therapeutics by Jung-Hwan Lee, Yeo Gyun Yun, Hae-Won Kim

“…Summary: The extracellular matrix (ECM) provides structural support and mechanical cues that profoundly influence cellular behavior via nuclear mechanotransduction. …”
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In vitro investigation of cartilage regeneration properties of polymeric ceramic hybrid composite by Mingchao Zhang, Yuejiao Liu, Yonggang Zhou, Yan Wang, Suresh Mickymaray, Abdulaziz S. Alothaim, Moorthy Kannaiyan, Xiaodong Li

“…FTIR, XRD, and SEM-EDAX were used to perform morphological and structural studies. The prepared composite's surface feature was investigated and discovered by HRTEM-SAED analysis, and it observed porous nature. …”
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Effect of SiC Content and Hot Compaction on the Microstructure, Thermal, Mechanical, and Tribological Characteristics of Aluminum Matrix Nanocomposites Produced via Powder Metallur... by ahmed Elmashad, A. Hassan, Mohamed El-Sheikh, Moustafa Mohammed, Mohamed Okail, Osama Irfan, A. Abu-Oqail

“….% SiC reinforcement and 600 °C compaction temperature offer an optimal balance of properties for structural applications, highlighting the significance of processing parameters in tailoring composite behaviour.…”
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Enhancing magnetic and electrochemical properties of cobalt modified ZnS nanoparticles: A facile synthesis approach by Pawan Kumar Pathak, Devendra Kumar, Santosh J. Uke, Amit Kumar Singh, Manika Chaudhary, Neha V. Brahmankar, Subodh Kumar Sharma, Beer Pal Singh, Ashwani Kumar

“…The Co doping-dependent structural, morphological, magnetic, optical, and electrochemical properties of the ZnS nanostructures were systematically explored. …”
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Recent Progress of Biomaterial-Based Hydrogels for Wearable and Implantable Bioelectronics by Baojin Chen, Yan Zhu, Renjie Yu, Yunxiang Feng, Zhenpeng Han, Chang Liu, Pengcheng Zhu, Lijun Lu, Yanchao Mao

“…Among the various materials explored for bioelectronic applications, hydrogels derived from natural biopolymers have emerged as highly promising candidates, owing to their inherent biocompatibility, mechanical compliance akin to biological tissues, and tunable structural properties. This review provides a comprehensive overview of recent advancements in the design and application of protein-based hydrogels, including gelatin, collagen, silk fibroin, and gluten, as well as carbohydrate-based hydrogels such as chitosan, cellulose, alginate, and starch. …”
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Unravelling the human taste receptor interactome: machine learning and molecular modelling insights into protein-protein interactions by Harry Zaverdas, Filip Stojceski, Rocío Romero-Zaliz, Lampros Androutsos, Pantelis Makrygiannis, Lorenzo Pallante, Vanessa Martos, Gianvito Grasso, Marco A. Deriu, Konstantinos Theofilatos, Seferina Mavroudi

“…To this end, we propose a comprehensive machine learning approach to accurately predict and quantify protein-protein interactions using an ensemble evolutionary algorithm. 1,647,374 positive and 894,213 negative experimentally verified protein-protein interactions were mined and characterized using 61 functional orthology, sequence, co-expression and structural features. The binary classifier significantly improved the accuracy of existing methods, reconstructing the full taste receptor interactome and was combined with a regressor that estimates the binding strength of positive interactions. …”
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A Drosophila ecdysone-deficient model to assess the endocrine disruptor activity of Bisphenol A by Patricia Vega-Cuesta, Diego Pulido, David Abia, Sandra Herrera, Ana Lopez-Varea, Ana Ruiz-Gómez, Paloma Fernández-Freire, Ana Peropadre, Jose F. de Celis

“…Furthermore, through in silico structural predictions of the Ecdysone receptor's ligand binding domain, we identified a protein domain capable of accommodating with different affinities ecdysone, Ponasterone A and BPA molecules. …”
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Carbon Fiber Composites of Pure Polypropylene and Maleated Polypropylene Blends Obtained from Injection and Compression Moulding by D. Pérez-Rocha, A. B. Morales-Cepeda, F. Navarro-Pardo, T. Lozano-Ramírez, P. G. LaFleur

“…The crystallisation behaviour of the composites was studied by differential scanning calorimetry. Morphological and structural features of these samples were observed by atomic field microscopy and Fourier-transform infrared spectroscopy, respectively. …”
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Unlocking playful dimensions: Developing and validating a scale for assessing video game-related hedonic experiences by Amir Zaib Abbasi, Ding Hooi Ting, Helmut Hlavacs, Bradley Wilson, Mousa Albashrawi, Yogesh K. Dwivedi

“…In the second phase, the partial least squares structural equation modeling (PLS-SEM) is applied to a sample of 444 Malaysian gamers to validate the scale at a higher-order level and evaluate the conceptual model’s acceptability. …”
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